Category: alcohols-buliding-blocks

Vorcakova, Katarina published the artcileSynthesis and characterization of new inhibitors of cholinesterases based on N-phenylcarbamates: In vitro study of inhibitory effect, type of inhibition, lipophilicity and molecular docking, Formula: C12H20O6, the publication is Bioorganic Chemistry (2018), 280-289, database is CAplus and MEDLINE.

Based on current treatment of Alzheimer’s disease, where the carbamate inhibitor Rivastigmine is used, two series of carbamate derivatives were prepared: (i) N-phenylcarbamates with addnl. carbamate group and (ii) N-phenylcarbamates with monosaccharide moiety. All compounds were tested for the inhibitory effect on both of the cholinesterases, elec. eel acetylcholinesterase (eeAChE) and butyrylcholinesterase from equine serum (eqBChE) and the inhibitory activity (expressed as IC₅₀ values) was compared with that of the established drugs Galanthamine and Rivastigmine. The compounds with two carbamate groups revealed higher inhibitory efficiency on both cholinesterases in compared with monosaccharide derived carbamates and with Rivastigmine. The significant decrease of inhibitory efficiency on eqBChE (also for eeAChE but in less manner) was observed after deacetalization of monosaccharide. Moreover, the type of inhibitory mechanism of five chosen compounds was studied. It was found, that compounds with two carbamate groups act presumably via a mixed inhibitory mechanism and the compounds with monosaccharide moiety act as noncompetitive inhibitors. The lipophilicity of tested compounds was determined using partition coefficient Specific positions of the inhibitors in the binding sites of cholinesterases were determined using mol. modeling and the results indicate the importance of phenylcarbamate orientation in the catalytic gorges of both enzymes.

Bioorganic Chemistry published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C8H10S, Formula: C12H20O6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Tomic, L. published the artcileTris(dipivaloyemethanato)holmium induced NMR shifts, Recommanded Product: 1-Methylcyclobutan-1-ol, the publication is Croatica Chemica Acta (1971), 267-9, database is CAplus.

The NMR of 1-methylcyclobutanol and 1-octanol were studied by means of complexes of Ho and Pr with 2,2,6,6-tetramethyl-3,5-heptanedione (DPM). The complex Ho(DPM)3 is a more powerful NMR shift reagent than Eu(DPM)3 and Pr(DPM)3, but introduces considerably stronger line broadening, spin-spin splittings being observable only for the most distant protons from the coordination site.

Croatica Chemica Acta published new progress about 20117-47-9. 20117-47-9 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic cyclic hydrocarbon,Alcohol, name is 1-Methylcyclobutan-1-ol, and the molecular formula is C17H18N2O6, Recommanded Product: 1-Methylcyclobutan-1-ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Horie, Masaki published the artcileCyclopentadithiophene based polymers; a comparison of optical, electrochemical and organic field-effect transistor characteristics, SDS of cas: 239075-02-6, the publication is Journal of Materials Chemistry (2010), 20(21), 4347-4355, database is CAplus.

A series of cyclopentadithiophene based polymers have been synthesized by oxidative polymerization or palladium-catalyzed coupling reactions. Polymers have been prepared with backbones containing benzothiadiazole, benzoxadiazole, 2,2′-bithiophene, Ph and fluorene units. The backbone structure is shown to have a large effect on the film morphol., and the optical and electrochem. properties in solution and the solid state. We show that the polymer composition can be used to tune the band gap over the entire visible spectrum. Spin-coated films of these polymers have been used as the active layer of organic field effect transistors and hole mobilities up to 3.7 × 10^-3 cm² V^-1 s^-1 have been measured under ambient conditions.

Journal of Materials Chemistry published new progress about 239075-02-6. 239075-02-6 belongs to alcohols-buliding-blocks, auxiliary class Thiophene,Boronic acid and ester,Boronate Esters, name is 5,5′-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,2′-bithiophene, and the molecular formula is C20H28B2O4S2, SDS of cas: 239075-02-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Dindarloo Inaloo, Iman published the artcileN-Arylation of (hetero)arylamines using aryl sulfamates and carbamates via C-O bond activation enabled by a reusable and durable nickel(0) catalyst, Safety of Thiophen-3-ol, the publication is New Journal of Chemistry (2020), 44(31), 13266-13278, database is CAplus.

An effective and general aryl amination protocol has been developed using a magnetically recoverable Ni(0) based nanocatalyst. This new stable catalyst was prepared on Fe₃O₄@SiO₂ modified by EDTA and investigated by FT-IR, EDX, TEM, XRD, DLS, FE-SEM, XPS, NMR, TGA, VSM, ICP and elemental anal. techniques. The reaction proceeded via carbon-oxygen bond cleavage of (hetero)aryl carbamates and sulfamates under simple and mild conditions without the use of any external ligands. This method demonstrated functional group tolerance in the N-arylation of various nitrogen-containing compounds as well as aliphatic amines, anilines, pyrroles, pyrazoles, imidazoles, indoles, and indazoles with good to excellent yields. Furthermore, the catalyst could be easily recovered by using an external magnetic field and directly reused at least six times without notable reduction in its activity.

New Journal of Chemistry published new progress about 17236-59-8. 17236-59-8 belongs to alcohols-buliding-blocks, auxiliary class Thiophene,Alcohol, name is Thiophen-3-ol, and the molecular formula is C4H4OS, Safety of Thiophen-3-ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Tawfic, Medhat L. published the artcileNatural abundant prodegradant for Oxo-degradation of polymers, Recommanded Product: Pentane-1,5-diol, the publication is Journal of Polymer Research (2022), 29(2), 60, database is CAplus.

In the present study, novel polypentane maleate (PPM)/linear low-d. polyethylene (LLPE) composites for potential medical disposables application as biodegradable pads were prepared Polypentane maleate as biodegradable polyester was prepared by adding stoichiometric amounts of maleic acid and pentane diol in presence of titanium tetrabutoxide as a catalyst. FT-IR, ¹HNMR and GPC were performed to elucidate the chem. structure of the prepared polymer. Preparation of oxo-degradable polymers (OBP) were achieved by compounding PPM, cellulosic fibers (CF) and LLPE. Synthetic prodegradant such as benzophenone and promising natural prodegradant such as extracted chlorophyll were added to the prepared composites. The polymeric composites were exposed to UV irradiation for different period to evaluate their oxo-degradation behavior. Carbonyl indexes were calculated for oxo-degradable polymers using FT-IR spectroscopy. Furthermore, X- Ray diffraction and differential scanning calorimetry (DSC) were conducted to follow up the crystallinity of the prepared samples. Mech. properties for polymeric composites were evaluated before and after UV exposure. Morphol. of the polymeric composites was investigated by scanning electron microscope. DSC anal. showed that chlorophyll enhances the decrease of crystallinity rather than benzophenone. As well as, mech. results revealed that chlorophyll lowers tensile strengths after 20 days of UV exposure less than in case of benzophenone. These results confirm that chlorophyll is efficient prodegradant.

Journal of Polymer Research published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C7H10O4, Recommanded Product: Pentane-1,5-diol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Li, Chunbao published the artcileEffect of triisopropanolamine on chloride binding of cement paste with ground-granulated blast furnace slag, Category: alcohols-buliding-blocks, the publication is Construction and Building Materials (2020), 119494, database is CAplus.

Chloride was one of important factors resulting in steel bar corrosion in reinforced concrete when using sea resources. In this paper, an attempt to promote the chloride binding capacity of the cement-ground-granulated blast furnace slag (GGBS) system was made by adding triisopropanolamine (TIPA). The paste was prepared by 70 wt% cement and 30 wt% GGBS, sodium chloride, TIPA (0.03%, 0.06% and 0.10%, by weight of binder) and water. The paste was cured for 7 d and 60 d, and the chloride binding ratio (CBR) were measured. The hydration heat and compressive strength were examined, then the hydrates and pore structure of the hardened paste were also analyzed; and the effect of TIPA on aluminum and ferric dissolution of GGBS was also studied. The results showed that TIPA could promote CBR at both 7 d and 60 d. The reason was ascribed to three aspects: (1) TIPA facilitate the formation of FS, which contribute to chem. binding; (2) TIPA promoted the formation of C-S(A)-H gel, which would increase the phys. binding; (3) TIPA refined the pore structure and increased fractal dimension, which could enhance the migration resistance. Furthermore, TIPA promoted cement hydration and pozzolanic reaction of GGBS by facilitated the dissolution of aluminum and ferric in GGBS. Addnl., the formation of Friedel’s salt was promoted due to the transformation of ettringite to AFm-like phase promoted by TIPA. Such results suggested a new way to improve chloride binding capacity of cementitious materials by adding alkanolamine.

Construction and Building Materials published new progress about 122-20-3. 122-20-3 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment, name is Triisopropanolamine, and the molecular formula is C9H21NO3, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Liu, Xiaohai published the artcileImprovement in chloride immobilization of cement-metakaolin system by triisopropanolamine, Product Details of C9H21NO3, the publication is Applied Clay Science (2020), 105656, database is CAplus.

Metakaolin (MK) is a widely used admixture in chloride immobilization which is conducive to the durability of reinforced concrete. In this study, triisopropanolamine (TIPA) was added into cement-MK system to improve the chloride immobilization by expediting the pozzolanic reaction of MK. The effect of TIPA on hydration of binder composed of 90% Portland cement and 10% MK was investigated, and the hydration behavior was characterized by thermogravimetric anal., X-ray diffraction, NMR spectroscopy, and mercury intrusion porosimetry, based on the evaluation of pozzolanic reaction of MK by ion dissolution Results indicated that TIPA promoted the hydration of both MK and cement, and chloride immobilization was also improved. The mechanism for the improvement was involved in three aspects: a) TIPA facilitated the dissolution of aluminum from MK to obtain more chloroaluminate salts, strengthening chem. binding; b) TIPA accelerated hydration of cement and MK for more C-S-H gel, conducive to the phys. adsorption; c) TIPA increased the amount of hydrates to refine the pore structure, hindering the migration of chloride ion. This investigation provided one new method for improving the pozzolanic reaction of MK to enhance chloride immobilization of cement-MK system.

Applied Clay Science published new progress about 122-20-3. 122-20-3 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment, name is Triisopropanolamine, and the molecular formula is C9H21NO3, Product Details of C9H21NO3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Wang, Jie published the artcileHydration and mechanical properties of cement-marble powder system incorporating triisopropanolamine, Related Products of alcohols-buliding-blocks, the publication is Construction and Building Materials (2021), 266(Part_B), 121068, database is CAplus.

This study aimed to improve the mech. properties of cement-marble powder (MP) mortar by incorporating triisopropanolamine (TIPA) to promote the optimal utilization of marble waste. In this research, the workability, compressive strength, capillary water absorption, hydration process and microstructure of cement-MP system were investigated. From the exptl. results, it was found that the incorporation of TIPA enhanced the mech. strength of cement-MP mortar. Moreover, the capillary water absorption of cement-MP mortar was improved when the TIPA dosage exceeded 0.06%. The enhancement of these properties was mainly due to the acceleration effect of TIPA on the cement-MP system hydration process, despite the fact that its air entraining effect would have a neg. effect. Incorporating TIPA in cement-MP system accelerated the dissolution of Fe3+ ions in ferrite phase to promote the hydration of cement, which certainly facilitated the consumption of SO2-4 ions, thus promoting the formation of calcium aluminocarbonate. Addnl., no obvious difference was observed in the workability and setting characteristics between cement-MP system with and without TIPA.

Construction and Building Materials published new progress about 122-20-3. 122-20-3 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment, name is Triisopropanolamine, and the molecular formula is C5H13Cl2N, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zhang, Ting published the artcileEffect of TIPA on mechanical properties and hydration properties of cement-lithium slag system, Recommanded Product: Triisopropanolamine, the publication is Journal of Environmental Management (2020), 111274, database is CAplus and MEDLINE.

Effect of triisopropanolamine (TIPA) on compressive strength and hydration properties of cement-lithium slag (LS, 30%) paste was studied. The results demonstrated that the addition of TIPA is advantageous for compressive strength at 7 d, 28 d and 60 d. The reason was related to the pore complexity and hydration process of cement and LS. TIPA reduced the total porosity, and increased the fractal dimension, making the pore structure more complicated. In addition, TIPA promoted the pozzolanic reaction of LS and the hydration of cement, expediting the formation of C-S(A)-H gel. TIPA accelerated the dissolution of aluminate ions, silicate ions and ferric ions in the pore solution, thereby accelerating the pozzolanic reaction of LS. During the hydration of cement-LS paste, TIPA facilitated the conversion of ettringite to the AFm-like phase and produced more C-A-S-H gel by promoting the dissolution of aluminate ions.

Journal of Environmental Management published new progress about 122-20-3. 122-20-3 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment, name is Triisopropanolamine, and the molecular formula is C15H20BNO2, Recommanded Product: Triisopropanolamine.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

An, Zhi-min published the artcileStructural changes of 2-keto-L-gulonic acid studied by NMR spectroscopy, Formula: C6H10O7, the publication is Bopuxue Zazhi (2014), 31(3), 407-414, database is CAplus.

2-Keto-L-gulonic acid (2-KLG) changes its mol. structure in many solvents at room temperature A five-membered intramol. ring structure can easily be formed by the 2,5-hemiacetal reaction after the opening of the carbonyl group in 2-KLG (-C=O) to form a O-C-O interlinkage. In this study, we showed that the ¹³C chem. shift of the carbonyl changed from δ200 towards high field to about δ96 after forming the intramol. ring. Two-dimensional HMBC experiments revealed that 2-keto-L-gulonic acid formed five-membered ring 2,5-hemiacetal derivatives in seven solvents, instead of six-membered 2,6-hemiacetal derivatives

Bopuxue Zazhi published new progress about 526-98-7. 526-98-7 belongs to alcohols-buliding-blocks, auxiliary class Sugar Units,Other Sugar Units, name is (3S,4R,5S)-3,4,5,6-Tetrahydroxy-2-oxohexanoic acid, and the molecular formula is C6H10O7, Formula: C6H10O7.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts