Author: tianli

Akondi, Srirama Murthy published the artcileAerobic, Diselenide-Catalyzed Redox Dehydration: Amides and Peptides, Name: 4,4-Diethoxybutan-1-amine, the publication is Organic Letters (2018), 20(3), 538-541, database is CAplus and MEDLINE.

At 2.5 mol % loadings using reaction temperatures between 30-55 °C, ortho-functionalized diaryl diselenides are highly effective organocatalytic oxidants for aerobic redox dehydrative amidic and peptidic bond formation using tri-Et phosphite as a simple terminal reductant. This simple-to-perform organocatalytic reaction relies on the ability of selenols to react directly with dioxygen in air without recourse to metal catalysts. It represents an important step toward the development of a general, economical, and benign catalytic redox dehydration protocol.

Organic Letters published new progress about 6346-09-4. 6346-09-4 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Ether, name is 4,4-Diethoxybutan-1-amine, and the molecular formula is C8H19NO2, Name: 4,4-Diethoxybutan-1-amine.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Forni, Jose A. published the artcileCarbonylative Hydroacylation of Styrenes with Alkyl Halides by Multiphoton Tandem Photoredox Catalysis in Flow, Name: Pentane-1,5-diol, the publication is ACS Catalysis (2022), 12(16), 10018-10027, database is CAplus.

The photocatalytic carbonylative hydroacylation of styrenes (R¹)R²C=CH₂ (R¹ = H, Ph, Me, Et; R² = Ph, naphthalen-2-yl, pyridin-2-yl, thiophen-2-yl, etc.) with inactivated alkyl halides RX (R = Cyclohexyl, cyclopentyl, n-Bu, i-Pr, etc.; X = Br, I) was reported. This protocol unifies the visible-light multiphoton catalytic cycle of [Ir(ppy)₂(dtb-bpy)]⁺ with flow chem. to engage energy-demanding alkyl bromides and iodides at moderate pressures of carbon monoxide. The mild and practical methodol. was employed to prepare a diverse array of 43 unsym. dialkyl ketones RC(O)CH₂CH(R¹)R² from primary, secondary, and tertiary inactivated alkyl halides. The application of flow chem. technol. to achieve spatially resolved chemoselectivity and broad functional group tolerance for the mild generation of functionalized C(sp³)-rich ketone products was demonstrated.

ACS Catalysis published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C5H12O2, Name: Pentane-1,5-diol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Xia, Shanghua published the artcileCopper-Catalyzed Hydroxylation of (Hetero)aryl Halides under Mild Conditions, Name: 4-(1H-Pyrrol-1-yl)phenol, the publication is Journal of the American Chemical Society (2016), 138(41), 13493-13496, database is CAplus and MEDLINE.

In the presence of Cu(acac)₂ and N,N’-bis(4-hydroxyl-2,6-dimethylphenyl)oxalamide, aryl and heteroaryl chlorides, bromides, and iodides underwent hydroxylation reactions in DMSO/H₂O to yield phenols and aryl and heteroaryl alcs. A wide range of aryl and heteroaryl chlorides bearing either electron-donating or electron-withdrawing groups underwent hydroxylation at 130 °C to provide the corresponding phenols and hydroxylated heteroarenes in 52-96% yields. When more reactive aryl and heteroaryl bromides and iodides were employed, the hydroxylation reactions could be performed at 80° and 60°, resp., using 0.5 mol% of Cu(acac)₂.

Journal of the American Chemical Society published new progress about 23351-09-9. 23351-09-9 belongs to alcohols-buliding-blocks, auxiliary class Pyrrole,Benzene,Alcohol, name is 4-(1H-Pyrrol-1-yl)phenol, and the molecular formula is C12H14BNO2, Name: 4-(1H-Pyrrol-1-yl)phenol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Andrieux, Claude P. published the artcileEvidence for Inverted Region Behavior in Proton Transfer to Carbanions, Application of 3,3,3-Trifluoropropan-1-ol, the publication is Journal of the American Chemical Society (2003), 125(33), 10119-10124, database is CAplus and MEDLINE.

The diphenylmethane-diphenylmethyl anion acid/base couple in N,N-dimethylformamide is taken as an example for investigating the dynamics of proton transfer at carbon in a system where the acid is not activated by an electron-withdrawing group or by removal of an electron. The laser flash electron photoinjection technique is applied to the determination of the rate constant for the protonation of diphenylmethyl anion by an extended series of acids that offers a range of driving forces encompassing over 1.2 eV. The plot of the rate constant vs. the pK_a difference between diphenylmethane and the acids or of the activation free energy vs. the standard free energy of the reaction exhibits clear “inverted region” behavior (by a factor of 80 in terms of rate constants). While such behaviors have been predicted and observed for outer-sphere electron-transfer reactions, previous evidence for proton-transfer reactions was scarce. Entropic factors, derived from an investigation of the temperature dependence of the exptl. rate constants, are also discussed.

Journal of the American Chemical Society published new progress about 2240-88-2. 2240-88-2 belongs to alcohols-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Aliphatic hydrocarbon chain,Alcohol, name is 3,3,3-Trifluoropropan-1-ol, and the molecular formula is C3H5F3O, Application of 3,3,3-Trifluoropropan-1-ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Chen, Kai published the artcileTransient Grating Photoluminescence Spectroscopy: An Ultrafast Method of Gating Broadband Spectra, Application In Synthesis of 239075-02-6, the publication is Journal of Physical Chemistry Letters (2014), 5(10), 1732-1737, database is CAplus and MEDLINE.

Ultrafast luminescence (PL) spectroscopy can cleanly resolve excited-state dynamics and coupling to the environment; there is a demand for new methods that combine broadband detection and low backgrounds. A new method, transient grating luminescence spectroscopy (TGPLS), addresses this challenge by exploiting a focusing geometry where ultrafast broadband spectra are transiently diffracted away from the background PL. TGPLS can resolve the complex spectral relaxation observed in conjugated polymer and oligomer solutions, with an essentially flat spectral response throughout the visible region and potentially beyond. The benefits demonstrated using TGPLS could expand access to spectral information, particularly for other multichromophoric and heterogeneous materials where complex spectral relaxation is expected.

Journal of Physical Chemistry Letters published new progress about 239075-02-6. 239075-02-6 belongs to alcohols-buliding-blocks, auxiliary class Thiophene,Boronic acid and ester,Boronate Esters, name is 5,5′-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,2′-bithiophene, and the molecular formula is C20H28B2O4S2, Application In Synthesis of 239075-02-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Jirasek, Fabian published the artcileSolid-Liquid Equilibrium in the System 2-Keto-L-Gulonic Acid + L-Ascorbic Acid + Water, SDS of cas: 526-98-7, the publication is Chemical Engineering & Technology (2018), 41(12), 2306-2311, database is CAplus and MEDLINE.

The solid-liquid equilibrium (SLE) in the ternary system 2-keto-L-gulonic acid (HKGA) + L-ascorbic acid (vitamin C) + water was investigated exptl. at temperatures between 276 K and 308 K at ambient pressure, i.e., under conditions that are of particular interest for industrial applications. Phase diagrams with one eutonic point were obtained for all temperatures The dissociation constant and the solubility constant of vitamin C were determined as a function of temperature Based on an extended version of the Debye-Hueckel theory, a physicochem. model was developed that describes the SLE in the ternary system. The agreement between exptl. data and results from the model is excellent.

Chemical Engineering & Technology published new progress about 526-98-7. 526-98-7 belongs to alcohols-buliding-blocks, auxiliary class Sugar Units,Other Sugar Units, name is (3S,4R,5S)-3,4,5,6-Tetrahydroxy-2-oxohexanoic acid, and the molecular formula is C6H10O7, SDS of cas: 526-98-7.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Dorival-Garcia, Noemi published the artcileIdentification of additives in polymers from single-use bioprocessing bags by accelerated solvent extraction and ultra-high performance liquid chromatography coupled with high-resolution mass spectrometry, Computed Properties of 122-20-3, the publication is Talanta (2020), 121198, database is CAplus and MEDLINE.

Single-use technologies are increasingly used in biopharmaceutical manufacturing Despite their advantages, these plastic assemblies draw concern because they are a potential source of contamination due to extractable and leachable compounds (E&Ls). Characterizing E&Ls from such materials is a necessary step in establishing their suitability for use. Therefore, there is an urgent need for sensitive methods to identify and quant. assess compounds in plastic materials. Accelerated solvent extraction (ASE) is a powerful technique that can be reliably used for this purpose. In this study, ASE followed by liquid chromatog. and Orbitrap-based High Resolution Accurate Mass (HRAM) mass anal. was found to be an efficient and versatile method for the determination of additives in different multilayer polymer systems from single-use bags. ASE optimization was performed using a design of experiments approach. The type of solvent, temperature, swelling agent addition, static time and number of cycles were the selected variables. Optimum conditions were dependent on the type of plastic film. Et acetate and cyclohexane were selected individually as optimum solvents. Optimum temperatures were 90-100°C. Pressure was set at 1500 psi and extraction time was 30 min in 2 cycles. Swelling agent addition was necessary with polar extraction solvents. More than 100 additives and degradation products were confidently identified by HRAM MS. Correlations between the type and levels of identified additives and the type of polymer system were established. In addition, degradation behavior and pathways for some additives can be addressed.

Talanta published new progress about 122-20-3. 122-20-3 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment, name is Triisopropanolamine, and the molecular formula is C9H21NO3, Computed Properties of 122-20-3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Lewandowska, Aneta published the artcileThiol-ene ionogels based on polymerizable imidazolium ionic liquids, Computed Properties of 111-29-5, the publication is Polymer Chemistry (2022), 13(21), 3154-3170, database is CAplus.

In this work, we report the synthesis of polymerizable ionic liquids (PILs) and the synthesis of ionogels by thiol-ene photopolymerization A series of gemini imidazolium-based bis(trifluoromethylsulfonyl)imide polymerizable ionic liquids with ene functional groups, reactive in thiol-ene polymerization, were synthesized. The obtained polymerizable ionic liquids differ by (i) type of reactive group: vinyl, allyl, (ii) length of hydrocarbon chain spacer (from C2 to C12) between two imidazole rings in cations in the vinyl series of PILs (divinyl-PIL), and (iii) type of substituent (-H or -CH₃) at C(2) position at the imidazole ring in diallyl-PILs. Then ionogel systems on the basis of the prepared PILs used as ene, 1,3,5-trimethylolpropane trimethacrylate (TMPTM), difunctional aliphatic polyester urethane acrylate (DAPU), and tris(3-mercaptobutyloxethyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione (TMTT) were synthesized in 70 wt% of ionic liquid 1-ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide (EMImNTf₂). The mech. properties (tensile strength), ionic conductivity (electrochem. impedance spectroscopy), and thermal properties (differential scanning calorimetry, thermogravimetric anal.) of the prepared ionogels as well as the course of photopolymerization by the photo-DSC method were studied. The resulting ionogels are fully transparent, highly flexible, with no leakage (also at an elevated temperature 80 °C and during mech. testing), all thanks to the presence of PILs in the polymer matrix of ionogels. Interestingly, DSC studies have shown that the ionic liquid EMImNTf₂ does not crystallize in the synthesized ionogels in a broad range of temperatures (-170 – 30 °). The PIL structure influences the polymerization kinetics as well as properties of ionogels. All synthesized ionogels are stable in the temperature range 304 °C-325 °C, and ionogels with allyl-PILs have higher thermal stability than ionogels with vinyl-PILs. The strength (for the ionogels with PILs C2-C6) and Young′s modulus of the obtained ionogels increase with the length of the hydrocarbon chain of the spacer in vinyl-PILs but elongation and ionic conductivity decrease. However, the conductivity of ionogels is greater than 1 mS cm^-1, which allows the use of the obtained materials, e.g., in electrochem. capacitors.

Polymer Chemistry published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C5H12O2, Computed Properties of 111-29-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zhong, Mingbing published the artcileCopper-Photocatalyzed Hydroboration of Alkynes and Alkenes, Category: alcohols-buliding-blocks, the publication is Angewandte Chemie, International Edition (2021), 60(26), 14498-14503, database is CAplus and MEDLINE.

The photocatalytic hydroboration of alkenes and alkynes is reported. The use of newly-designed copper photocatalysts with B₂Pin₂ permits the formation a boryl radical, which is used for hydroboration of a large panel of alkenes and alkynes. The hydroborated products were isolated in high yields, with excellent diastereoselectivities and a high functional group tolerance under mild conditions. The hydroboration reactions were developed under continuous flow conditions to demonstrate their synthetic utility. The reaction mechanism was studied and suggested an oxidation reaction between an in situ formed borate and the Cu-photocatalyst in its excited state for the boryl radical formation.

Angewandte Chemie, International Edition published new progress about 608534-44-7. 608534-44-7 belongs to alcohols-buliding-blocks, auxiliary class Other Aromatic,Boronic acid and ester,Boronate Esters,Boronic Acids,Boronic acid and ester, name is 2-(2,3-Dihydro-1H-inden-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, and the molecular formula is C15H24S, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Ojha, Devi Prasan published the artcileGeneration of Hydrogen from Water: A Pd-Catalyzed Reduction of Water Using Diboron Reagent at Ambient Conditions, Application In Synthesis of 25240-59-9, the publication is Organic Letters (2016), 18(19), 5062-5065, database is CAplus and MEDLINE.

Production of hydrogen from renewable sources, particularly from water, is an intensive area of research, which has far-reaching relevance in hydrogen economy. A homogeneous catalytic method is presented for producing clean hydrogen gas from water, in a reaction of water with a diboron compound as the reductant, under ambient reaction conditions. The Pd-catalytic system is stable in water and displays excellent recyclability. Hydroxy analogs such as alcs. are compatible with the Pd/B₂Pin₂ system and generate hydrogen gas efficiently. The B₂Pin₂-H₂O system, in the presence of palladium, is an excellent catalytic system for selective hydrogenation of olefins.

Organic Letters published new progress about 25240-59-9. 25240-59-9 belongs to alcohols-buliding-blocks, auxiliary class Boronic acid and ester,Boronic Acids,Boronate Esters, name is 4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-ol, and the molecular formula is C6H13BO3, Application In Synthesis of 25240-59-9.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts