Author: tianli

Meng, Xiangzhan published the artcileSelective Oxidation of Amino Alcohols to Amino Acids over Au Supported on Monoclinic ZrO₂: Dominant Active Sites and Kinetic Study, Safety of 2-Aminobutan-1-ol, the publication is Industrial & Engineering Chemistry Research (2019), 58(19), 8506-8516, database is CAplus.

Au supported on monoclinic ZrO₂ (Au/m-ZrO₂) prepared by deposition-precipitation method showed excellent catalytic performance in the aerobic oxidation of amino alcs. to amino acids, i.e., glycine, alanine, serine, β-alanine, and 2-aminobutyric acid. The Au particle size and valence distribution of the gold species were adjusted by calcination temperature, as demonstrated by XRD, TEM, UV-vis DRS, XPS, and H₂-TPR, which significantly influenced the catalytic activity but not the selectivity of amino acids. Metallic gold atoms on the surface were shown to be the active sites by the correlation between reaction rate per mol of metallic Au and Au particle size. The kinetics of oxidation of monoethanolamine (MEA) was studied in detail, and the results indicated that MEA oxidation is a first-order reaction with an activation energy of 52.8 kJ·mol^-1.

Industrial & Engineering Chemistry Research published new progress about 96-20-8. 96-20-8 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 2-Aminobutan-1-ol, and the molecular formula is C4H11NO, Safety of 2-Aminobutan-1-ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Lin, Bai-zhu published the artcileComparison between Hemabate and oxytocin in preventing and treating postpartum hemorrhage in pregnant women with high-risk cesarean section, Related Products of alcohols-buliding-blocks, the publication is Xiandai Zhenduan Yu Zhiliao (2015), 26(20), 4646-4647, database is CAplus.

The clin. data of 106 pregnant women undergoing cesarean section were retrospectively analyzed, and they were randomly divided into control group and observation group with 53 cases each. The control group was given 20U i.v. infusion of oxytocin and 10U uterine muscle injection, and the observation group was given 20U i.v. infusion of oxytocin and 250 μg uterine muscle injection of Hemabate. The bleeding volume and urine volume of the two groups of pregnant women during operation, 2h and 24h postpartum were compared and recorded, and the occurrence of adverse reactions in the two groups was observed The bleeding amount of the control group during surgery, 2h and 24h postpartum was significantly higher than that of the observation group (P < 0.05), and the urine output was lower than that of the observation group (P < 0.05). There were no significant differences in common adverse reactions (such as nausea, vomiting, palpitations, headaches, etc.) between the two groups (P > 0.05). Hemabate has a significant clin. effect compared with oxytocin in preventing and treating postpartum hemorrhage of high-risk cesarean pregnant women, and has fewer adverse reactions and higher safety, which is suitable for clin. use.

Xiandai Zhenduan Yu Zhiliao published new progress about 58551-69-2. 58551-69-2 belongs to alcohols-buliding-blocks, auxiliary class Chiral,Alkenyl,Amine,Aliphatic cyclic hydrocarbon,Ester,Alcohol,Inhibitor,, name is 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid, and the molecular formula is C25H47NO8, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Liu, Miao published the artcileClinical research of carboprost tromethamine for preventing and treating postpartum hemorrhage of high risk puerpera undergoing cesarean, HPLC of Formula: 58551-69-2, the publication is Xiandai Zhongxiyi Jiehe Zazhi (2013), 22(2), 144-145, 205, database is CAplus.

The objective was to observe the effect and security of carboprost tromethamine for preventing and treating postpartum hemorrhage of high risk puerpera undergoing cesarean. The method includes dividing 397 puerpera undergoing cesarean with high risk of postpartum hemorrhage into 3 groups: oxytocin group (injection of 20 IU oxytocin into hyster and i.v. infusion of 20 IU oxytocin, n=131), oxytocin+carboprost tromethamine group (injection of 20 IU oxytocin 20 IU+carboprost tromethamine 250μg into hyster, n=152), and carboprost tromethamine group (injection of carboprost tromethamine 250μg into hyster, n=114), calculating bleeding amount during the cesarean and 2 h after cesarean and the total bleeding amount, and observing the untoward effects. The results show that carboprost tromethamine can significantly reduce the bleeding amount during the cesarean and after cesarean, and the combination of carboprost tromethamine and oxytocin has better effect, and the untoward effect is little.

Xiandai Zhongxiyi Jiehe Zazhi published new progress about 58551-69-2. 58551-69-2 belongs to alcohols-buliding-blocks, auxiliary class Chiral,Alkenyl,Amine,Aliphatic cyclic hydrocarbon,Ester,Alcohol,Inhibitor,, name is 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid, and the molecular formula is C25H47NO8, HPLC of Formula: 58551-69-2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zhao, Xin-qi published the artcileNon targeted metabonomics analysis of small molecular substances in fermented cereal drinks, Computed Properties of 86-48-6, the publication is Xiandai Shipin Keji (2021), 37(10), 96-102, 18, database is CAplus.

Millet, glutinous rice and other cereals were used as main raw materials. Two probiotics, L. paracasei L1 and L. casei YQ336, isolated from naturally fermented sweet potato sour liquid and tofu sour liquid were used as fermentation bacteria. Non targeted metabonomics technol. was used to analyze the differences of small mol. substances in cereal drinks before and after fermentation Through principal component anal. (PCA) and orthogonal partial least squares discriminant anal. (OPLS-DA), it was found that there were 25 categories and 145 differential metabolites with significant changes (VIP>1 and p<0.05) in beverages before and after fermentation, mainly including 34 organic acids and their derivatives, 21 flavonoids, 20 sugars and their derivatives, 16 alkaloids, 10 nucleotides and their derivatives 10 amino acids and their derivatives The bioactive substances with significantly increased content after fermentation include 36668 times of 1-hydroxy-2-naphthoic acid, 1000 times of dihydroresveratrol, 800 times of 2-hydroxyvaleric acid, 517 times of daidzein, 488 times of vitexin, 238 times of apigenin, 148 times of isoerucic acid, 130 times of genistein, etc. The anal. of KEGG metabolic pathway showed that there were 19 metabolic pathways with significant differences. It is speculated that grain substrate may have certain effects on the synthesis and accumulation of secondary metabolism of L. paracasei L1 and L. casei YQ336. This study will lay a theor. foundation for the fermentation of plant matrix food by lactic acid bacteria and the metabolic mechanism of plant matrix.

Xiandai Shipin Keji published new progress about 86-48-6. 86-48-6 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment,Natural product, name is 1-Hydroxy-2-naphthoic acid, and the molecular formula is C6H8N2, Computed Properties of 86-48-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Huang, M. published the artcileAntioxidant effect of glutathione on promoting 2-keto-L-gulonic acid production in vitamin C fermentation system, HPLC of Formula: 526-98-7, the publication is Journal of Applied Microbiology (2018), 125(5), 1383-1395, database is CAplus and MEDLINE.

The study aims to investigate the antioxidant effect of glutathione on promoting 2-KGA in Vc fermentation system using Ketogulonicigenium vulgare 25B-1 and Bacillus endophyticus ST-1 as the co-culturing microbes. Methods and Results : The activities of antioxidant-related enzymes and qPCR were used to study the antioxidant effect of glutathione addition in Vc fermentation system. The addition of GSH and GSH/GSSG increased 2-KGA production and decreased fermentation time, and the highest 2-KGA production increased by 40·63% and the lowest fermentation time shortened to 60 h when the addition of optimal concentration ratio of GSH/GSSG was 50 : 1. Moreover, the increased production of 2-KGA was accompanied by up-regulated the activities of total antioxidant capacity (T-AOC), total superoxide dismutase (T-SOD), catalase (CAT) and over-expressed oxidative stress-related genes sod,gst,gr,zwf,gp, which resulted in scavenging reactive oxygen species to reduce oxidative stress in Vc fermentation system. Conclusions : Glutathione showed a significant effect on increasing 2-KGA production and decreasing fermentation time in Vc fermentation system. GSH/GSSG could maintain a dynamic balance with two forms of glutathione and the optimal concentration ratio of GSH/GSSG was 50 : 1. Significance and Impact of the Study : Glutathione is proved to be effective to relieve oxidative stress. The promotion effects of GSSG and GSH on 2-KGA production could help to further explore the optimization of co-culture fermentation process for Vc industrial production

Journal of Applied Microbiology published new progress about 526-98-7. 526-98-7 belongs to alcohols-buliding-blocks, auxiliary class Sugar Units,Other Sugar Units, name is (3S,4R,5S)-3,4,5,6-Tetrahydroxy-2-oxohexanoic acid, and the molecular formula is C6H10O7, HPLC of Formula: 526-98-7.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zhang, Yanrong published the artcileA further understanding on the strength development of cement pastes in the presence of triisopropanolamine used in CRTS III slab track, Synthetic Route of 122-20-3, the publication is Construction and Building Materials (2022), 125743, database is CAplus.

Accelerators are commonly used in the self-compacting concrete of CRTS III slab track to advance its strength development in cold areas. Triisopropanolamine (TIPA) is a known accelerator, and its influences on the strength development of hardened cement pastes (HCPs) were discussed based on a further understanding of cement hydration and microstructure. The results show that the addition of TIPA visibly heightens hydration degree at each age because it triggers the reaction of C4AF and gently promotes C3S hydration. At low dosages, more hydrates deposited in capillary pores facilitate a refined pore structure and therefore, significantly increase the early and late strengths. On the contrary, a high dosage of TIPA results in a loose and porous structure at an early age owing to the emergence of numerous AFm platelets and the reduction of Ca(OH)₂ crystals, so that the heightened hydration degree only slightly increases the early compressive and flexural strengths. At a later age, high dosages of TIPA cause an increase in the volume of harmful pores (greater than 50 nm), which may result from the appearance of some pores full of fractional AFm and the changed morphol. of Ca(OH)₂. Therefore, the late compressive strength of HCPs remains almost unchanged under the pos. effect of the heightened hydration degree coupled with the neg. effect of the increased volume of the harmful pores. In contrast, the late flexural strength sharply decreases, which is ascribed to both of the increased volume of the pores larger than 50 nm and the morphol. changes of hydration products.

Construction and Building Materials published new progress about 122-20-3. 122-20-3 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment, name is Triisopropanolamine, and the molecular formula is C24H20Ge, Synthetic Route of 122-20-3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Sui, Rui published the artcileSilver based single atom catalyst with heteroatom coordination environment as high performance oxygen reduction reaction catalyst, HPLC of Formula: 80-09-1, the publication is Nano Research (2022), 15(9), 7968-7975, database is CAplus.

Ag is a potential low-cost oxygen reduction reaction (ORR) catalyst in alk. condition, which is important for the zinc-air batteries. Here, we report that an Ag based single atom catalyst with heteroatom coordination. Ag₁-h-NPClSC, has been synthesized and shown much improved performance towards ORR by manipulating the coordination environment of the Ag center. It shows a high half wave potential (0.896 V) and a high turnover frequency (TOF) (5.9 s^-1) at 0.85 V, which are higher than the previously reported Ag based catalysts and com. Pt/C. A zinc-air battery with high peak power d. of 270 mW·cm^-2 is fabricated by using the Ag₁-h-NPClSC as air electrode. The high performance is attributed to (1) the hollow structure providing good mass transfer; (2) the single atom metal center structure providing high utility of the Ag; (3) heteroatom coordination environment providing the adjusted binding to the ORR intermediates. D. functional theory (DFT) calculations show that the energy barrier for the formation of OOH*, which is considered as the rate determine step for ORR on Ag nanoparticles, is lowered on Ag₁-h-NPClSC, thus improving the ORR activity. This work demonstrates that the well manipulated Ag based single atom catalysts are promising in electrocatalysis.

Nano Research published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C13H10F2, HPLC of Formula: 80-09-1.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

McCulloch, Iain published the artcilePolymerizable liquid crystalline organic semiconductors and their fabrication in organic field effect transistors, Computed Properties of 239075-02-6, the publication is Journal of Materials Chemistry (2003), 13(10), 2436-2444, database is CAplus.

The performance of the semiconducting component in organic field effect transistors (OFETs) is a key parameter in the advancement of organic electronic devices. New semiconductors are required, which can be solution processed, possess high mobility and current modulation, and are stable in ambient conditions. This work provides the first demonstration of working field effect transistor devices fabricated from novel solution processible, polymerizable, small mol. liquid crystalline semiconductors, referred to as reactive mesogens. The design, synthesis, and performance of these materials in transistor devices are reported. The relationship between liquid crystal mol. structure, its corresponding phase behavior and elec. performance is examined Mol. design methodol. was employed to control the liquid crystalline morphol., in an attempt to optimize organization and packing. Alignment of the mols. in large homeotropic domains was achieved through surface treatment techniques, and the highly ordered mesophase was preserved by polymerization of the reactive end groups, creating a crosslinked network.

Journal of Materials Chemistry published new progress about 239075-02-6. 239075-02-6 belongs to alcohols-buliding-blocks, auxiliary class Thiophene,Boronic acid and ester,Boronate Esters, name is 5,5′-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,2′-bithiophene, and the molecular formula is C20H28B2O4S2, Computed Properties of 239075-02-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Xue, Da-quan published the artcileSynthesis of dapoxetine hydrochloride, Product Details of C19H18O2, the publication is Hecheng Huaxue (2010), 18(5), 647-649, database is CAplus.

Dapoxetine hydrochloride was synthesized from 3-chloropropiophenone by catalytic asym. reduction, alkylation, O-methylsulfonylation, and dimethylamination, as well as salt formation in an overall yield of 39.9%.

Hecheng Huaxue published new progress about 156453-53-1. 156453-53-1 belongs to alcohols-buliding-blocks, auxiliary class Chiral,Benzene,Naphthalene,Alcohol,Ether, name is (R)-3-(Naphthalen-1-yloxy)-1-phenylpropan-1-ol, and the molecular formula is C10H15ClO3S, Product Details of C19H18O2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Sun, Li published the artcileReactive polyurethane hot melt adhesives based on polycarbonate and sebacic acid-based polyester polyols, Formula: C5H12O2, the publication is Journal of Adhesion Science and Technology, database is CAplus.

Reactive polyurethane hot melt adhesives (HMPURs) containing a blend of polyester and polycarbonate diols can typically exhibit balanced performance, such as bonding properties, tensile strength, and heat resistance. Two series of HMPURs made from poly(1,4-butylene adipate) or sebacic acid (SeA)-based polyester diols with different mol. weights were prepared and investigated. Increasing the mol. weight of the SeA-based polyester diols was found to significantly improve their mech. properties and lap shear strengths. Moreover, the HMPURs made from SeA-based polyester diol exhibited better performances than those made from poly(1,4-butylene adipate). Also, the HMPURs were more suitable for bonding on PC substrate.

Journal of Adhesion Science and Technology published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C6H5NO, Formula: C5H12O2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts