Month: October 2022

Tang, Yun-Zhi’s team published research in Journal of Coordination Chemistry in 2009-08-20 | 6054-98-4

Journal of Coordination Chemistry published new progress about Crystal structure. 6054-98-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C14H8N2Na2O6, Safety of Sodium 5,5′-(diazene-1,2-diyl)bis(2-hydroxybenzoate).

Tang, Yun-Zhi; Tan, Yu-Hui; Ge, Zong-Tang; Liu, Zhen-Xin; Liao, Chun-Fa; Xie, Xiao-Bin published the artcile< Synthesis and crystal structures of two rare-earth metal polymers of olsalazine>, Safety of Sodium 5,5′-(diazene-1,2-diyl)bis(2-hydroxybenzoate), the main research area is rare earth olsalazine phenanthroline polymer complex preparation structure; europium gadolinium olsalazine phenanthroline polymer complex preparation structure; crystal structure europium gadolinium olsalazine phenanthroline polymer complex.

Two 1-dimensional linear coordination polymers, {[Gd2(L)2·(Phen)2·2(H2O)·2(NO3)]·2(EtOH)}n (1, H2L = olsalazine) and {[Eu2(L)2·(Phen)2·2(H2O)·2(NO3)]·EtOH}n (2), were obtained from self-assembly of Gd(NO3)3·8H2O or Eu(NO3)3·8H2O with olsalazine. Both complexes are 1-dimensional polymers, for 1 with crystal data: space group P1̅, a 11.651(4), b 11.865(4), and c 12.296(4) Å, α 77.984(4), β 65.559(4), and γ 74.558(5)°, Z = 1, R1 = 0.0389, wR2 = 0.0793, and 2 with crystal data: space group P1̅, a 11.626(3), b 11.834(3), c 12.287(4) Å, α 77.743(3), β 65.576(3), γ 74.371(3)°, Z = 1, R1 = 0.0609, wR2 = 0.1185. Central atoms (Gd or Eu) in both complexes adopt nine-coordinate tricapped trigonal prismatic geometry.

Journal of Coordination Chemistry published new progress about Crystal structure. 6054-98-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C14H8N2Na2O6, Safety of Sodium 5,5′-(diazene-1,2-diyl)bis(2-hydroxybenzoate).

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Weng, Shidan’s team published research in Molecules in 2021 | 78-70-6

Molecules published new progress about 78-70-6. 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, SDS of cas: 78-70-6.

Weng, Shidan; Fu, Xueqing; Gao, Yu; Liu, Tianlei; Sun, Yi; Tang, Dongqin published the artcile< Identification and Evaluation of Aromatic Volatile Compounds in 26 Cultivars and 8 Hybrids of Freesia hybrida>, SDS of cas: 78-70-6, the main research area is Freesia hybrida; VOCs; floral scent; heterosis; monoterpenes.

Freesia hybrida is a group of cultivars in the genus Freesia with a strong floral scent composed of diverse volatile organic compounds (VOCs). In this study, the VOCs of 34 F. hybrida were extracted and analyzed by headspace solid phase microextraction and gas chromatog. mass spectrometry (HS-SPME-GC-MS). A total of 164 VOCs whose relative contents were higher than 0.05% were detected. The numbers of VOCs in all germplasms differed between 11 to 38, and the relative contents ranged from 32.39% to 94.28%, in which most germplasms were higher than 80%. Terpenoids, especially monoterpenes, were the crucial type of VOCs in most germplasms, of which linalool and D-limonene were the most frequently occurring. Principal component anal. (PCA) clearly separated samples based on whether linalool was the main component, and hierarchical clustering anal. (HCA) clustered samples into 4 groups according to the preponderant compounds linalool and (E)-β-ocimene. Comparison of parental species and hybrids showed heterosis in three hybrids, and the inherited and novel substances suggested that monoterpene played an important role in F. hybrida floral scent. This study established a foundation for the evaluation of Freesia genetic resources, breeding for the floral aroma and promoting com. application.

Molecules published new progress about 78-70-6. 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, SDS of cas: 78-70-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Nifei’s team published research in Carbohydrate Polymers in 2020-01-01 | 3458-28-4

Carbohydrate Polymers published new progress about Asparagus (white). 3458-28-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Recommanded Product: (2S,3S,4R,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Wang, Nifei; Zhang, Xiaojun; Wang, Shaowei; Guo, Qingbin; Li, Zhenjing; Liu, Huanhuan; Wang, Changlu published the artcile< Structural characterisation and immunomodulatory activity of polysaccharides from white asparagus skin>, Recommanded Product: (2S,3S,4R,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is immunomodulatory polysaccharide asparagus skin; Immunomodulatory; NMR; Pectin; Polysaccharide; Structure; White asparagus skin.

The physicochem. properties, structural features and immunomodulatory effects of the white asparagus (Asparagus officinalis L.) skin polysaccharides (WASP) were systematically studied. WASP showed a pectic-like structure with a relatively low degree of esterification (DE, 18%); the weight-average mol. weight (Mw) and intrinsic viscosity were 76.1 kDa and 13 mL/g, resp. Structurally, the dominated sugar residue of WASP was 4-α-D-GalpA (39.7 mol%), while other residues including α-L-Araf, 3-α-L-Rhap, 2,4-α-L-Rhap, and 4-β-D-Galp were also detected with a comparable amount A proposed structure of WASP was also presented. Physiol., WASP could modulate the immune response of RAW 264.7 macrophages through increasing the release of immune factors (IL-6, TNF-α and IL-10) and improving the expression of mRNA. To conclude, the pectic-like polysaccharides from white asparagus (Asparagus officinalis L.) skin could be potentially used as an immunomodulatory agent in functional food.

Carbohydrate Polymers published new progress about Asparagus (white). 3458-28-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Recommanded Product: (2S,3S,4R,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yang, Bo’s team published research in Nature Communications in 2021-12-31 | 10602-04-7

Nature Communications published new progress about Alkynes, internal Role: RCT (Reactant), RACT (Reactant or Reagent). 10602-04-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C9H8O, Recommanded Product: (4-Ethynylphenyl)methanol.

Yang, Bo; Li, Shi-Jun; Wang, Yongdong; Lan, Yu; Zhu, Shifa published the artcile< Hydrogen radical-shuttle (HRS)-enabled photoredox synthesis of indanones via decarboxylative annulation>, Recommanded Product: (4-Ethynylphenyl)methanol, the main research area is phenylglyoxalic acid acetylene iridium photocatalyst regioselective decarboxylative cyclization; dihydroindenone preparation.

In this work, a HRS-enabled decarboxylative annulation of carbonyl compounds via photoredox catalysis for the synthesis of indanones was developed. This protocol features broad substrate scope, excellent functional group tolerance, internal hydrogen radical transfer, atom- and step-economy. Critical to the success of this process is the introduction of water, acting as both HRS and hydrogen source, which was demonstrated by mechanistic experiments and d. functional theory (DFT) calculations Importantly, this mechanistically distinctive HAT provides a complement to that of typical proton-shuttle-promoted, representing a breakthrough in hydrogen radical transfer, especially in the inherently challenging 1,2- or 1,3-HAT.

Nature Communications published new progress about Alkynes, internal Role: RCT (Reactant), RACT (Reactant or Reagent). 10602-04-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C9H8O, Recommanded Product: (4-Ethynylphenyl)methanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Martin, Ian J.’s team published research in Macromolecules (Washington, DC, United States) in 2020 | CAS: 4048-33-3

6-Aminohexan-1-ol(cas: 4048-33-3) can undergo cyclization over copper supported on γ-alumina and magnesia to form hexahydro-1H-azepine. It may be used along with glutaric acid to generate poly(ester amide)s with excellent film- and fiber forming properties.Related Products of 4048-33-3

Related Products of 4048-33-3In 2020 ,《Templated Supramolecular Structures of Multichromic, Multiresponsive Perylene Diimide-Polydiacetylene Films》 was published in Macromolecules (Washington, DC, United States). The article was written by Martin, Ian J.; Shih, Kuo-Chih; Nieh, Mu-Ping; Kasi, Rajeswari M.. The article contains the following contents:

We report a detailed synthesis and characterization of novel polymeric supramol. structures composed of semiconducting perylene diimide (PDI)-imidazole templates of varying methylene spacer length (n = 3, 4, and 6) hydrogen-bonded to a conjugated polymer backbone of acid-functionalized polydiacetylene (PDA), 10,12 pentacosadiynoic acid. First, a combination of mol. and morphol. characterization tools confirmed that the templated supramol. structures are a result of the synergistic effect of intermol. PDI π-π stacking coupled with noncovalent imidazole-acid interactions. Second, a simple and scalable solid-state polymerization of the drop-cast films by UV radiation delivers multichromic, multiresponsive films capable of unique phase/morphol.-switching properties with a high degree of local ordering. Thermal studies by differential scanning calorimetry and morphol. studies by wide- and small-angle X-ray scattering (WAXS/SAXS, resp.) show dramatic morphol. effects and trends in crystallinity with methylene spacer group extension. Furthermore, UV-vis studies displayed an unusual PDA “”purple phase”” transition, which was addnl. verified by SAXS as a coexistence of previously known red- and blue-phase PDA. Finally, the polymerized drop-cast films displayed reversible thermo- and solvatochromic responses after a second treatment of UV radiation and addnl. UV-thermal cycling revealed the extent of reversibility. The results came from multiple reactions, including the reaction of 6-Aminohexan-1-ol(cas: 4048-33-3Related Products of 4048-33-3)

6-Aminohexan-1-ol(cas: 4048-33-3) can undergo cyclization over copper supported on γ-alumina and magnesia to form hexahydro-1H-azepine. It may be used along with glutaric acid to generate poly(ester amide)s with excellent film- and fiber forming properties.Related Products of 4048-33-3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Houze, Jonathan B.’s team published research in Bioorganic & Medicinal Chemistry Letters in 2012 | CAS: 865233-35-8

(S)-3-(4-Hydroxyphenyl)hex-4-ynoic acid(cas: 865233-35-8) belongs to alkynes. The addition of nonpolar E−H bonds across C≡C is general for silanes, boranes, and related hydrides. The hydroboration of alkynes gives vinylic boranes which oxidize to the corresponding aldehyde or ketone. In the thiol-yne reaction the substrate is a thiol.Application In Synthesis of (S)-3-(4-Hydroxyphenyl)hex-4-ynoic acid

《AMG 837: A potent, orally bioavailable GPR40 agonist》 was published in Bioorganic & Medicinal Chemistry Letters in 2012. These research results belong to Houze, Jonathan B.; Zhu, Liusheng; Sun, Ying; Akerman, Michelle; Qiu, Wei; Zhang, Alex J.; Sharma, Rajiv; Schmitt, Michael; Wang, Yingcai; Liu, Jiwen; Liu, Jinqian; Medina, Julio C.; Reagan, Jeff D.; Luo, Jian; Tonn, George; Zhang, Jane; Lu, Jenny Ying-Lin; Chen, Michael; Lopez, Edwin; Nguyen, Kathy; Yang, Li; Tang, Liang; Tian, Hui; Shuttleworth, Steven J.; Lin, Daniel C.-H.. Application In Synthesis of (S)-3-(4-Hydroxyphenyl)hex-4-ynoic acid The article mentions the following:

The discovery that certain long chain fatty acids potentiate glucose stimulated insulin secretion through the previously orphan receptor GPR40 sparked interest in GPR40 agonists as potential antidiabetic agents. Optimization of a series of β-substituted phenylpropanoic acids led to the identification of (S)-3-(4-((4′-(trifluoromethyl)biphenyl-3-yl)methoxy)phenyl)hex-4-ynoic acid (AMG 837) as a potent GPR40 agonist with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents. The experimental part of the paper was very detailed, including the reaction process of (S)-3-(4-Hydroxyphenyl)hex-4-ynoic acid(cas: 865233-35-8Application In Synthesis of (S)-3-(4-Hydroxyphenyl)hex-4-ynoic acid)

(S)-3-(4-Hydroxyphenyl)hex-4-ynoic acid(cas: 865233-35-8) belongs to alkynes. The addition of nonpolar E−H bonds across C≡C is general for silanes, boranes, and related hydrides. The hydroboration of alkynes gives vinylic boranes which oxidize to the corresponding aldehyde or ketone. In the thiol-yne reaction the substrate is a thiol.Application In Synthesis of (S)-3-(4-Hydroxyphenyl)hex-4-ynoic acid

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Leubner, Sebastian’s team published research in Angewandte Chemie, International Edition in 2019 | CAS: 401797-00-0

2-(3,4-Dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(cas: 401797-00-0) belongs to hydroxy-containing compounds. Hydroxy groups participate in the dehydration reactions that link simple biological molecules into long chains. The joining of a fatty acid to glycerol to form a triacylglycerol removes the −OH from the carboxy end of the fatty acid.Recommanded Product: 401797-00-0

《Expanding the Variety of Zirconium-based Inorganic Building Units for Metal-Organic Frameworks》 was published in Angewandte Chemie, International Edition in 2019. These research results belong to Leubner, Sebastian; Zhao, Haishuang; Van Velthoven, Niels; Henrion, Mickael; Reinsch, Helge; De Vos, Dirk E.; Kolb, Ute; Stock, Norbert. Recommanded Product: 401797-00-0 The article mentions the following:

Two new Zr-based metal-organic frameworks [Zr6O4(OH)4(OAc)6(BDC)3] (CAU-26) and [Zr5O4(OH)4(OAc)4(BDC)2] (CAU-27) are reported, which were synthesized from HOAc, a rarely used but green and sustainable solvent (BDC2-: 1,4-benzenedicarboxylate). Structure determination aided by automated electron diffraction tomog. revealed that CAU-26 [Zr6O4(OH)4(OAc)6(BDC)3] is composed of layers of known {Zr6O8} clusters interconnected by terephthalate ions. In contrast CAU-27 [Zr5O4(OH)4(OAc)4(BDC)2] exhibits a three-dimensional structure with a so far unknown type of 1-dimensional inorganic building unit (IBU), which can be rationalized as condensed polyhedron-sharing chains of {Zr6O8} clusters. CAU-26 occurs as an intermediate of the CAU-27 synthesis and can be isolated easily, when reaction temperature and time are decreased. The authors were also able to synthesize two isoreticular derivatives of CAU-27 with extended linker mols. by implementing 4,4′-biphenyldicarboxylic acid (H2BPDC) and 5,5′-dicarboxy-2,2′-bipyridine (H2BIPY). All materials show high thermal and chem. stability as well as permanent microporosity. The excellent stability of CAU-27-BIPY was exploited to synthesize an Ir-supported heterogeneous MOF-based catalyst for the direct C-H borylation of arenes. In the experimental materials used by the author, we found 2-(3,4-Dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(cas: 401797-00-0Recommanded Product: 401797-00-0)

2-(3,4-Dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(cas: 401797-00-0) belongs to hydroxy-containing compounds. Hydroxy groups participate in the dehydration reactions that link simple biological molecules into long chains. The joining of a fatty acid to glycerol to form a triacylglycerol removes the −OH from the carboxy end of the fatty acid.Recommanded Product: 401797-00-0

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Sadati Sorkhi, Seyyed Erfan’s team published research in Research on Chemical Intermediates in 2020 | CAS: 100-83-4

3-Hydroxybenzaldehyde(cas: 100-83-4) is used as an ionophore, during the development of an highly selective and sensitive PVC membrane sensor, which can be used as a Tb3+ ion selective electrode.Category: alcohols-buliding-blocks

《Introduction of a novel dicationic Bronsted acidic ionic liquid based on pyrazine and its application in the synthesis of xanthenediones and 3, 4-dihydropyrimidin-2(1H)-ones under solvent-free conditions》 was written by Sadati Sorkhi, Seyyed Erfan; Hashemi, Mohammad M.; Ezabadi, Ali. Category: alcohols-buliding-blocksThis research focused onxanthenedione preparation green chem; dimethyl cyclohexanedione aryl aldehyde cyclocondensation ionic liquid catalyst; pyrimidinone preparation green chem; aryl aldehyde ethyl acetoacetate urea cyclocondensation ionic liquid catalyst; pyrazine acidic ionic liquid preparation. The article conveys some information:

A novel dicationic Bronsted acidic ionic liquid based on pyrazine I has been prepared and characterized by FTIR, 1H NMR, 13C NMR, MS, thermal gravimetric and differential thermal gravimetric anal. and also Hammett acidity function. The prepared dicationic ionic liquid I is found to be an efficient and reusable catalyst for the synthesis of xanthenediones II (Ar = Ph, 2-bromophenyl, thiophen-2-yl, etc.) and 3,4-dihydropyrimidin-2(1H)-ones III (Ar1 = 3-chlorophenyl, thiophen-2-yl, 4-fluorophenyl, etc.) under solvent-free conditions. The merits of the developed procedure include novelty in terms of the ionic liquid, easy preparation of the ionic liquid, I easy workup, reusability of the catalyst, high yield, short reaction time and absence of toxic organic solvent.3-Hydroxybenzaldehyde(cas: 100-83-4Category: alcohols-buliding-blocks) was used in this study.

3-Hydroxybenzaldehyde(cas: 100-83-4) is used as an ionophore, during the development of an highly selective and sensitive PVC membrane sensor, which can be used as a Tb3+ ion selective electrode.Category: alcohols-buliding-blocks

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Tang, Luying’s team published research in International Journal of Biological Macromolecules in 2022 | CAS: 54-17-1

rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol(cas: 54-17-1) is the monohydrate form of the alpha isoform of D-glucopyranose, a synthetic simple monosaccharide that is used as an energy source.Reference of rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol

Reference of rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraolOn June 1, 2022, Tang, Luying; Sun, Yanhui; Ge, Peipei; Chen, Lei; Cheung, Peter C. K.; Ding, Zhongyang; Fang, Jinshan published an article in International Journal of Biological Macromolecules. The article was 《Biogenetic nanocarriers with enhanced pH stability formed by zein and selectively depolymerized mushroom hyperbranched β-glucans》. The article mentions the following:

Hyperbranched polysaccharide from Pleurotus tuber-regium (PTR-HBPS) is a βamp;beta;-glucan with high degree of branching (DB, 0.69) and a mol. weight (Mw) of 31.2 x 105 g/mol with mixed βamp;beta;-1, 4/ββ-1, 4, 6β/β-1, 6 glucosidic linkages. PTR-HBPS was depolymerized by cellulase and βamp;beta;-glucosidase under optimized conditions to form PC (PTR-HBPS depolymerized by cellulase) and PG (PTR-HBPS depolymerized by βamp;beta;-glucosidase) fractions with a min. Mw of 2.74 x 105 and 3.98 x 105 g/mol, resp. PC fractions had no significant changes for its primary structure in terms of glycosidic linkages, DB, and triple helical structure, while the DB of PG fractions was reduced to 0.63 with the loss of triple helical structure. Nanoparticles fabricated by PC fractions with zein showed better stability under different pH conditions. Enzymic depolymerized low Mw β-glucan derived from PTR-HBPS with similar structural characteristics as the native one has potential as nanocarriers for food bioactive substances. The experimental process involved the reaction of rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol(cas: 54-17-1Reference of rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol)

rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol(cas: 54-17-1) is the monohydrate form of the alpha isoform of D-glucopyranose, a synthetic simple monosaccharide that is used as an energy source.Reference of rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ganda, Sylvia’s team published research in Macromolecules (Washington, DC, United States) in 2021 | CAS: 20880-92-6

((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol(cas: 20880-92-6) is a useful reactant for examining the effectiveness of sulfamate and sulfamide groups for the inhibition of carbonic anhydrase-​II (CA-​II)​. And it is used as chiral auxiliaries in Michael and Aldol addition reactions.COA of Formula: C12H20O6

Ganda, Sylvia; Wong, Chin Ken; Stenzel, Martina H. published an article in Macromolecules (Washington, DC, United States). The title of the article was 《Corona-Loading Strategies for Crystalline Particles Made by Living Crystallization-Driven Self-Assembly》.COA of Formula: C12H20O6 The author mentioned the following in the article:

Self-assembled block copolymer (BCP) nanoparticles offer exciting opportunities for drug delivery applications. A key feature of using BCP nanoparticles for drug delivery is their ability to accommodate therapeutic cargoes within their particle core. This has become widely established for BCP nanoparticles with an amorphous core. The same, however, cannot be achieved with BCP nanoparticles with a crystalline core. This is because the encapsulation of therapeutic cargoes in a crystalline particle core disrupts crystallinity and ultimately leads to particle disassembly. Herein, we present several strategies to incorporate therapeutics and other functional cargoes onto the surface of crystalline particles, as this helps to ensure that the crystallinity of the particle core is maintained and the particle morphol. is hence unaffected. As a platform to showcase our strategies, in this study, we used biodegradable and bioactive 2D glycoplatelets prepared by living crystallization-driven self-assembly (CDSA). Specifically, we show that we can incorporate either an anticancer drug, doxorubicin (DOX), or a fluorescent dye, Cyanine5 (Cy5), onto the surface of glycoplatelets by seeded growth of prefunctionalized polymers or via postmodification using polymers with reactive handles. We believe that the strategies presented herein are versatile and should thus be applicable to other CDSA systems. Overall, our findings present new opportunities for crystalline particles to be used in drug delivery application.((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol(cas: 20880-92-6COA of Formula: C12H20O6) was used in this study.

((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol(cas: 20880-92-6) is a useful reactant for examining the effectiveness of sulfamate and sulfamide groups for the inhibition of carbonic anhydrase-​II (CA-​II)​. And it is used as chiral auxiliaries in Michael and Aldol addition reactions.COA of Formula: C12H20O6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts