Month: April 2022

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Rivero-Crespo, Miguel; Oliver-Meseguer, Judit; Kaplonska, Klaudia; Kustrowski, Piotr; Pardo, Emilio; Ceron-Carrasco, Jose Pedro; Leyva-Perez, Antonio researched the compound: Dichloro(1,5-cyclooctadiene)platinum(II)( cas:12080-32-9 ).SDS of cas: 12080-32-9.They published the article 《Cyclic metal(oid) clusters control platinum-catalysed hydrosilylation reactions: from soluble to zeolite and MOF catalysts》 about this compound( cas:12080-32-9 ) in Chemical Science. Keywords: platinum zeolite metal organic framework alkyne alkene alc hydrosilylation. We’ll tell you more about this compound (cas:12080-32-9).

The Pt-catalyzed addition of silanes to functional groups such as alkenes, alkynes, carbonyls and alcs., i.e. the hydrosilylation reaction, is a fundamental transformation in industrial and academic chem., often claimed as the most important application of Pt catalysts in solution However, the exact nature of the Pt active species and its mechanism of action is not well understood yet, particularly regarding regioselectivity. Here, exptl. and computational studies together with an ad hoc graphical method show that the hydroaddn. of alkynes proceeds through Pt-Si-H clusters of 3-5 atoms (metal(oid) association) in ppm amounts (ppm), which decrease the energy of the transition state and direct the regioselectivity of the reaction. Based on these findings, new extremely-active (ppm) microporous solid catalysts for the hydrosilylation of alkynes, alkenes and alcs. have been developed, paving the way for more environmentally-benign industrial applications.

Here is just a brief introduction to this compound(12080-32-9)SDS of cas: 12080-32-9, more information about the compound(Dichloro(1,5-cyclooctadiene)platinum(II)) is in the article, you can click the link below.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Chemical Communications (Cambridge, United Kingdom) called Ruthenium-catalyzed synthesis of N-substituted lactams by acceptorless dehydrogenative coupling of diols with primary amines, Author is Zheng, Yanling; Nie, Xufeng; Long, Yang; Ji, Li; Fu, Haiyan; Zheng, Xueli; Chen, Hua; Li, Ruixiang, which mentions a compound: 7661-33-8, SMILESS is O=C1N(C2=CC=C(Cl)C=C2)CCC1, Molecular C10H10ClNO, HPLC of Formula: 7661-33-8.

The first example of synthesis of N-substituted lactams I (R = Ph, 4-(propan-2-yl)phenyl, 2H-1,3-benzodioxol-5-yl, naphthalen-2-yl, etc.; n = 1,2,3) and N-(p-tolyl)isoindolin-2-one via an acceptorless dehydrogenative coupling of diols HO(CH2)2(CH2)nCH2OH and [2-(hydroxymethyl)phenyl]methanol with primary amines RNH2 in one step, which was enabled by combining Ru3(CO)12 with a hybrid N-heterocyclic carbene-phosphine-phosphine ligand as the catalyst have been reported.

Here is just a brief introduction to this compound(7661-33-8)HPLC of Formula: 7661-33-8, more information about the compound(1-(4-Chlorophenyl)pyrrolidin-2-one) is in the article, you can click the link below.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Gulledge, Zachary Z.; Carrick, Jesse D. published an article about the compound: tert-Butyl 5-bromo-1H-indazole-1-carboxylate( cas:651780-02-8,SMILESS:CC(C)(C)OC(=O)N1N=CC2=CC(Br)=CC=C12 ).Name: tert-Butyl 5-bromo-1H-indazole-1-carboxylate. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:651780-02-8) through the article.

Continued pursuit of functionalized soft-N-donor complexant scaffolds with favorable solubility and kinetics profiles applicable for the separation of the trivalent minor actinides from the lanthanides has attracted significant interest over the last three decades. Recent work from this laboratory resulted in the production of various N-Boc protected [1,2,4]triazinyl-pyridin-2-yl indole Lewis basic procomplexants which necessitated the removal of the indole N-Boc protecting group prior to evaluation of complexant efficacy in separations assays. Traditional deprotection strategies involving trifluoroacetic and other protic and Lewis acids proved unsuccessful in removal of the recalcitrant indole-N-Boc protecting group necessitating the development of a new strategy for deprotection of this complexant class. A serendipitous result facilitated utilization of 3-methoxypropylamine as a mild deprotecting agent for various N-Boc protected heteroarenes via a proposed addition-elimination mechanism. Method development, application to various heteroarenes including indoles, 1,2-indazoles, 1,2-pyrazoles, and related derivatives, a ten-fold scale-up reaction, and exptl. evaluation of a preliminary mechanistic hypothesis are reported herein.

Here is just a brief introduction to this compound(651780-02-8)Name: tert-Butyl 5-bromo-1H-indazole-1-carboxylate, more information about the compound(tert-Butyl 5-bromo-1H-indazole-1-carboxylate) is in the article, you can click the link below.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Nuclear-substituted derivatives of 4,4′-diaminodiphenyl sulfone》. Authors are Berg, S. S..The article about the compound:3-Bromo-4-chloronitrobenzenecas:16588-26-4,SMILESS:BrC1=C(C=CC(=C1)[N+](=O)[O-])Cl).Application of 16588-26-4. Through the article, more information about this compound (cas:16588-26-4) is conveyed.

The therapeutic effect of (4-H3NC6H4)3SO3 prompted the investigation of the halogen derivatives; these were tested orally in vivo against Staphylococcus aureus and Streptococcus pyogenes in mice; a decrease in toxicity in the order Cl < Br < iodine, together with corresponding decrease in activity, was observed 2,4-Br(O2N)C6H3NH2 (18.5 g.), through the diazo reaction, gives 12.5 g. 1-chloro-2-bromo-4-nitrobenzene, b0.1 100°, m. 61°. p-O2NC6H4SH (1.55 g.) and 0.4 g. NaOH in 20 cc. EtOH, added to 1.9 g. 3,4-Cl2C6H3NO2 in 10 cc. EtOH and refluxed 2 h., give 1.3 g. 2-chloro-4,4'-dinitrodiphenyl sulfide (I), yellow, m. 144°; the 2-Br analog, yellow, m. 159°, and the 2-I analog, yellow, m. 168°. 3,4-Cl2C6H3NO2 (15 g.) in 60 cc. EtOH, treated (5 min.) with 10 g. Na2S.9H2O in 40 cc. 25% aqueous EtOH and refluxed 6 h., gives 7.2 g. [2,4-Cl(O2N)C6H3]2S, yellow, m. 163°; the portion (3 g.) insoluble in 95% AcOH is the compound C24H12O5N4Cl4S2, probably RN(→O):NR, where R = 3,4-Cl[2,4-Cl(O2N)C6H3S]C6H3S-, red, m. 195°. 2,2'-Diiodo-4,4'-dinitrodiphenyl sulfide (II), pale red, m. 186°. 2,4-Br(O2N)C6H3OH yields an acetate (III), pale yellow, m. 86°; 13 g. III, 7.8 g. p-O2NC6H4SH, 3 g. K2CO3, and 100 cc. Me2CO, refluxed 2 h., yield 6 g. 4,4'-dinitro-2-acetoxydiphenyl sulfide (IV), yellow, m. 100°. Dropwise addition of 7.5 g. KMnO4 in 50 cc. hot H2O to 10 g. I in 150 cc. boiling AcOH gives 8 g. 2-chloro-4,4'-dinitrodiphenyl sulfone (V), m. 182-3°; 2-Br analog, m. 162°, 2-I analog, pale yellow, m. 165°; the sulfone from II, yellow, m. 260°. IV yields 4,4'-dinitro-2-hydroxydiphenyl disulfone, yellow, m. 216°. Reduced Fe (10 g.), added slowly to 5 g. V in 200 cc. boiling AcOH and the mixture heated 10 min. at 90°, gives 3 g. 2-chloro-4,4'-diaminodiphenyl sulfone, pale yellow, m. 114°; 2-Br analog, yellow, m. 157°; 2-I analog, buff, m. 207°. 2,2'-Dichloro-4,4'-diaminodiphenyl sulfone, orange, m. 263°; 2,2'-di-I analog, m. 280°. 4,4'-Diamino-2-hydroxydiphenyl sulfone, m. 134-5° [sulfate, m. 208° (decomposition)] (cf. Burton and Hoggarth, C.A. 39, 4854.7). Here is just a brief introduction to this compound(16588-26-4)Application of 16588-26-4, more information about the compound(3-Bromo-4-chloronitrobenzene) is in the article, you can click the link below.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Molecular orbital study of the NMR and electronic spectra of monocyanopyridines, dicyanopyridines, and 2,4,6-tricyanopyridine, published in 1970, which mentions a compound: 1195-58-0, mainly applied to mol orbitals cyaonopyridines; cyanopyridines mol orbitals; orbitals mol cyanopyridines; NMR cyanopyridines; electronic spectra cyanopyridines, Recommanded Product: Pyridine-3,5-dicarbonitrile.

The Hueckel MO and SCF methods gave identical results in the determination of quantum-chem. characteristics of 10 cyanopyridines. A good agreement between the exptl. absorption curves and electronic transitions, calculated by the limited configuration interaction (LCI) method, was obtained in the electronic spectra. In the PMR spectra, there was an improved correlation with the exptl. data in the use of the SCF method only in the case of chem. shifts and π-electron d. The application of the SCF orbitals in the place of Hueckel MO in the LCI calculation of the electronic spectra did not improve significantly the description of the π-electron structure of the compounds studied.

Here is just a brief introduction to this compound(1195-58-0)Recommanded Product: Pyridine-3,5-dicarbonitrile, more information about the compound(Pyridine-3,5-dicarbonitrile) is in the article, you can click the link below.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 1195-58-0, is researched, SMILESS is N#CC1=CC(C#N)=CN=C1, Molecular C7H3N3Journal, Izvestiya Akademii Nauk Kazakhskoi SSR, Seriya Khimicheskaya called Synthesis and reactions of 3-methyl-5-cyanopyridine under oxidative ammonolysis conditions, Author is Suvorov, B. V.; Belova, N. A., the main research direction is ammoxidation lutidine vanadia titania catalyst; cyanomethylpyridine preparation catalyst; methyl nicotinonitrile preparation catalyst; pyridine cyano methyl preparation catalyst.Safety of Pyridine-3,5-dicarbonitrile.

V2O5-TiO2 (1:32) was recommended over 1:16 V2O5-TiO2, 1:0.5 V2O5-SnO2 and 2:1 V2O5-Fe2O3 for the title synthesis, >90% selectivity with 100% 3,5-butadiene (I) conversion at 340° with 1:24:10:10-40 I-O2-NH3-H2O. The 3,5-dicyanopyridine yield was 4.2-5.3% under these conditions, but reached 65.2% at 380° in the absence of H2O.

Here is just a brief introduction to this compound(1195-58-0)Safety of Pyridine-3,5-dicarbonitrile, more information about the compound(Pyridine-3,5-dicarbonitrile) is in the article, you can click the link below.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Flexible Platinum(0) Coordination to a Ditungsten Ethanediylidyne, published in 2019, which mentions a compound: 12080-32-9, mainly applied to crystal structure platinum coordinate ditungsten ethanediylidyne complex; mol structure platinum coordinate ditungsten ethanediylidyne complex; platinum NMR coordinate ditungsten ethanediylidyne complex; bis(carbyne)s; carbido ligands; carbynes; dicarbido ligands; polymetallic compounds, Category: alcohols-buliding-blocks.

The lithiocarbyne [W(CLi)(CO)2(Tp*)] (Tp*=hydrotris(3,5-dimethylpyrazol-1-yl)borate) reacts with [PtCl2(L2)] (L2 = 1,5-cyclo-octadiene, norbornadiene) to furnish ditungsten ethanediylidyne complexes, [W2{μ-C2Pt(L2)}(CO)4(Tp*)2], wherein a trigonal platinum(0) center unsym. ligates one W C bond in the solid state but rapidly shimmies between the two W C bonds in solution The η4-dienes are displaced by monodentate CO or isocyanide ligands to provide derivatives where both W C bonds coordinate to a single Pt0 center, attended by significant distortion of the WCCW spine.

Here is just a brief introduction to this compound(12080-32-9)Category: alcohols-buliding-blocks, more information about the compound(Dichloro(1,5-cyclooctadiene)platinum(II)) is in the article, you can click the link below.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Ebrahimi, A.; Habibi-Khorasani, S. M.; Jahantab, M. researched the compound: Pyridine-3,5-dicarbonitrile( cas:1195-58-0 ).Reference of Pyridine-3,5-dicarbonitrile.They published the article 《Additivity of substituent effects on the proton affinity and gas-phase basicity of pyridines》 about this compound( cas:1195-58-0 ) in Computational & Theoretical Chemistry. Keywords: pyridine substituent effect additivity proton affinity gas phase basicity. We’ll tell you more about this compound (cas:1195-58-0).

The change in the proton affinity (PA) and basicity (GB) of pyridine with substituents have been considered by quantum mech. methods at the B3LYP/6-311++G(d,p) level of theory. The PA and GB values increase by the electron-donating substituents and decrease by the electron-withdrawing substituents. The effects of substituents on the PA and GB are approx. additive. The deviations of changes that are predicted from the additivity of substituent effects are generally lower than 30% from the calculated changes. Linear relationships are observed between the calculated PA values of substituted pyridines and the topol. properties of electron d., the mol. electrostatic potentials (MEP), and the N-H bond lengths. In addition, well-defined relations are established between the calculated PA values and the Hammett constants, and the reaction constant (ρ) has been calculated for the protonation reaction. With some exceptions, the effect of substituents are also additive on the electron d. and its Laplacian calculated at N-H BCP, and the MEP values calculated around the N atom.

Here is just a brief introduction to this compound(1195-58-0)Reference of Pyridine-3,5-dicarbonitrile, more information about the compound(Pyridine-3,5-dicarbonitrile) is in the article, you can click the link below.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 12080-32-9, is researched, Molecular C8H12Cl2Pt, about Synthesis and transition metal complexes of 1,1′-bis(diphenylethynylphosphino)ferrocene, the main research direction is diphenylethynylphosphinoferrocene preparation crystal mol structure transition metal complexation; crystal mol structure diphenylethynylphosphinoferrocene transition metal complex.Computed Properties of C8H12Cl2Pt.

The new ferrocene based bisphosphine [Fe{C5H4P(CCPh)2}2] (1) was synthesized in 82% yield by the treatment of bis(dichlorophosphino)ferrocene [Fe(C5H4PCl2)2] with four equivalent of lithium phenylacetylide. The reactions of 1 with aqueous H2O2, elemental sulfur or selenium afforded bis(chalcogenide) derivatives, [Fe{C5H4P(E)(CCPh)2}2] (2 E = O, 3 E = S, 4 E = Se). The reaction of 1 with [M(NC5H11)2(CO)4] (M = Mo, W), [RuCp(PPh3)2Cl] and [M(COD)Cl2] (M = Pd, Pt) resulted in the formation of the resp. chelate complexes, [Fe{C5H4P(CCPh)2}2{M(CO)4}] (5 M = Mo, 6 M = W), [Fe{C5H4P(CCPh)2}2{RuCp(Cl)}] (8) and [Fe{C5H4P(CCPh)2}2{MCl2}] (9 M = Pd, 10 M = Pt), whereas the reaction of 1 with [Ru(η6-p-cymene)Cl2]2 and [AuCl(SMe2)] yielded the corresponding bimetallic complexes [Fe{C5H4P(CCPh)2}2{RuCl2(η6-p-cymene)}2] (7) and [Fe{C5H4P(CCPh)2}2{AuCl}2] (15). The reactions between 1 and CuX in equimolar ratios also yielded binuclear complexes, [Fe{C5H4P(CCPh)2}2{CuX}2] (11 X = Cl, 12 X = Br, 13 X = I), whereas [Cu(CH3CN)4]BF4 yielded the cationic complex [(Fe{C5H4P(CCPh)2}2)2Cu]BF4 (14). All the compounds were characterized by spectroscopic methods and the structures of complexes 1, 5, 6, 8, 10, 13 and 14 were confirmed by single crystal x-ray diffraction studies.

Here is just a brief introduction to this compound(12080-32-9)Computed Properties of C8H12Cl2Pt, more information about the compound(Dichloro(1,5-cyclooctadiene)platinum(II)) is in the article, you can click the link below.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

HPLC of Formula: 16588-26-4. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: 3-Bromo-4-chloronitrobenzene, is researched, Molecular C6H3BrClNO2, CAS is 16588-26-4, about Development of a Tripeptide Mimetic Strategy for the Inhibition of Protein Farnesyltransferase. Author is Kothare, Mohit A.; Ohkanda, Junko; Lockman, Jeffrey W.; Qian, Yimin; Blaskovich, Michelle A.; Sebti, Said M.; Hamilton, Andrew D..

This paper describes the development of a novel terphenyl-based tripeptide mimetic of the CAAX carboxy terminal sequence of Ras. We employ a concise synthesis to form a series of differently functionalized terphenyl inhibitors of protein farnesyltransferase (PFTase), exemplified by I [R = (S)-HSCH2CH(NH2)CH2- (II); R = HS-3-C6H4C(O)- (III); R = HSCH2CH2C(O)- (IV)]. The key reaction in the synthesis of the terphenyl Me ester, and therefore III and IV, was the Pd-catalyzed chemoselective Suzuki cross-coupling of 3-bromo-4-chloronitrobenzene with an appropriate boronic acid derivative utilizing a com. available, electron rich phosphine ligand. We further show that II is a potent inhibitor of PFTase.

Here is just a brief introduction to this compound(16588-26-4)HPLC of Formula: 16588-26-4, more information about the compound(3-Bromo-4-chloronitrobenzene) is in the article, you can click the link below.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts