Tag: M.W=150-200

Golombek, Florian published the artcileThree Steps, Two Enzymes, One Pot, but a Multitude of Nanocompartments: Combined Cycles of Kinetic Resolutions and Re-racemization with Incompatible Biocatalysts, Product Details of C8H8O3, the publication is ACS Omega (2021), 6(43), 29192-29200, database is CAplus and MEDLINE.

Deracemizations are clearly preferable to kinetic resolutions in the production of chiral mols. from racemates, as they allow up to 100% chem. and optical yield. Here we present a new process route for multienzymic deracemizations that is relevant for reaction systems with incompatible reaction conditions of the biocatalysts. This often applies to combinations of lipases used for stereoselective acylation and solvent-sensitive racemases. By encapsulating a model racemase in polymeric vesicles, it was protected from inactivation by the organic solvent up to phase proportions of 99%. As high yields in the lipase reaction required either water proportions well below 1% or racemase-denaturating acyl donor concentrations, a one-pot reaction was implemented through the sequential use of lipase and racemase-containing nanocompartments. This strategy allowed us to perform two kinetic resolutions with intermittent re-racemization in one pot yielding 72% (0.72 mM after 120 h) of an enantiopure product.

ACS Omega published new progress about 90-64-2. 90-64-2 belongs to alcohols-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Alcohol,Natural product, name is 2-Hydroxy-2-phenylacetic acid, and the molecular formula is C8H8O3, Product Details of C8H8O3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Mohamedshah, Zulfiqar published the artcileBioaccessibility, gut microbial metabolism and intestinal transport of phenolics from 100% Concord grape juice and whole grapes are similar in a simulated digestion and fecal fermentation model, Application of 3-Hydroxyphenylacetic acid, the publication is Food & Function (2022), 13(8), 4315-4330, database is CAplus and MEDLINE.

Phenolic rich 100% grape juice has been associated with many health benefits, but its place in dietary guidance is controversial relative to whole fruit. Direct comparisons of phenolic profiles and bioavailability between these food forms are needed. Phenolic bioaccessibility and metabolism from Concord (CG) and Niagara (NG) grapes and corresponding 100% juices were investigated using an in vitro digestion coupled with anaerobic gut fermentation model. Intestinal transport of resulting bioaccessible phenolics and microbial metabolites was estimated using a Caco-2 cell model. Total bioaccessible phenolics from both upper and lower digestion were similar (P > 0.05) between NG (400.9 ± 26.3 μmol per 100 g) and NGJ (349.5 ± 8.3 μmol per 100 g) and significantly different (P < 0.05) between CG (417.2 ± 24.4 μmol per 100 g) and CGJ (294.3 ± 45.4 μmol per 100 g) total cellular transport of phenolics was similar (P > 0.05) between whole grapes (89.4 ± 5.3 μmol per 100 g for CG, and 71.8 ± 2.4 μmol per 100 g for NG) and 100% juices (88.0 ± 5.6 μmol per 100 g for CGJ, and 85.3 ± 9.4 μmol per 100 g for NGJ). Differences were observed between the location of phenolic metabolism, bioaccessibility and subsequent cellular transport of individual phenolics between grapes and juice matrixes. Specifically, greater amounts of phenolics were transported from grape juices than whole grapes from the upper tract. However, cumulative bioaccessibility and transport from upper and lower GI digestion/fermentation together indicates that the absorbable phenolics from 100% grape juice is similar to that of whole grapes, suggesting that phenolic-mediated health benefits from consumption of whole fruit and juice may be similar.

Food & Function published new progress about 621-37-4. 621-37-4 belongs to alcohols-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Phenol,Natural product, name is 3-Hydroxyphenylacetic acid, and the molecular formula is C8H8O3, Application of 3-Hydroxyphenylacetic acid.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Fan, Xiaodong published the artcileVisible light-induced deoxygenation/cyclization of salicylic acid derivatives and aryl acetylene for the synthesis of flavonoids, Name: 1-Hydroxy-2-naphthoic acid, the publication is Chemical Communications (Cambridge, United Kingdom) (2022), 58(43), 6348-6351, database is CAplus and MEDLINE.

A visible-light-induced photocatalytic strategy for the synthesis of flavonoids was developed through the deoxygenative/cyclization reaction of salicylic acid derivatives with aryl acetylene using di-Ph sulfide as an O-transfer reagent. Based on the controlled experiments, the mechanism of visible-light-induced free radical coupling cyclization was proposed. The protocol obtained 51 flavonoids in good yields and was successfully applied to the synthesis of some natural flavones.

Chemical Communications (Cambridge, United Kingdom) published new progress about 86-48-6. 86-48-6 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment,Natural product, name is 1-Hydroxy-2-naphthoic acid, and the molecular formula is C11H8O3, Name: 1-Hydroxy-2-naphthoic acid.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Li, Na published the artcileDesign, synthesis and preliminary evaluation of novel imperatorin derivatives as vasorelaxant agents, SDS of cas: 101-98-4, the publication is Medicinal Chemistry (2011), 7(1), 18-23, database is CAplus and MEDLINE.

A series of novel imperatorin derivatives (I) were synthesized from com. available xanthotoxin. The in vitro pharmacol. evaluation indicated that all of the compounds possessed potent vasodilatory activity. Among them, compounds (5b) (I, R = allyl), (5d) (I, R = -CH₂CH₂piperidinyl) and (5e) (I, R = -CH₂CH₂azepanyl) exhibited higher vasodilatory activity (with EC₅₀ values of 0.68 μM, 0.59 μM and 0.49 μM, resp.) than imperatorin (EC₅₀ = 1.12 μM). The program Volsurf was used to predict the derivatives’ ADME-relevant descriptors. The results suggested that these novel compounds had a potential interest for the development of novel and potent vasorelaxant agents.

Medicinal Chemistry published new progress about 101-98-4. 101-98-4 belongs to alcohols-buliding-blocks, auxiliary class Amine,Benzene,Alcohol, name is 2-(Benzyl(methyl)amino)ethanol, and the molecular formula is C10H15NO, SDS of cas: 101-98-4.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Su, Dan published the artcileAroma effects of key volatile compounds in Keemun black tea at different grades: HS-SPME-GC-MS, sensory evaluation, and chemometrics, Synthetic Route of 106-25-2, the publication is Food Chemistry (2022), 373(Part_B), 131587, database is CAplus and MEDLINE.

The present study aimed to explore the relationship between the grade and the characteristic aroma in Keemun black tea (KBT). Headspace solid-phase microextraction (HS-SPME), gas chromatog.-mass spectrometry (GC-MS), sensory evaluation, and chemometrics were employed to determine the changes in the flavor evolution of KBT at grade. The results showed that a total of 110 volatile components were identified. Linalool and linalool oxide were dominant. The orthogonal partial least squares discriminant anal. (OPLS-DA) combined with relative odor activity value (rOAV > 0.1) revealed that 11 volatile components were the key volatile compounds of KBT, such as benzeneacetaldehyde (rOAV: 3.43-5.96) and Me salicylate (rOAV: 2.15 – 2.50). Furthermore, the partial least squares (PLS) model indicated that geraniol, linalool, and Me salicylate benefited from the reservation of floral flavor of Keemun aroma characteristic of KBT. The findings presented in this thesis add to our understanding of KBT at different grades.

Food Chemistry published new progress about 106-25-2. 106-25-2 belongs to alcohols-buliding-blocks, auxiliary class Natural product, name is cis-3,7-Dimethyl-2,6-Octadien-1-Ol, and the molecular formula is C6H13NO2, Synthetic Route of 106-25-2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Su, Dan published the artcileAroma effects of key volatile compounds in Keemun black tea at different grades: HS-SPME-GC-MS, sensory evaluation, and chemometrics, Synthetic Route of 90-64-2, the publication is Food Chemistry (2022), 373(Part_B), 131587, database is CAplus and MEDLINE.

The present study aimed to explore the relationship between the grade and the characteristic aroma in Keemun black tea (KBT). Headspace solid-phase microextraction (HS-SPME), gas chromatog.-mass spectrometry (GC-MS), sensory evaluation, and chemometrics were employed to determine the changes in the flavor evolution of KBT at grade. The results showed that a total of 110 volatile components were identified. Linalool and linalool oxide were dominant. The orthogonal partial least squares discriminant anal. (OPLS-DA) combined with relative odor activity value (rOAV > 0.1) revealed that 11 volatile components were the key volatile compounds of KBT, such as benzeneacetaldehyde (rOAV: 3.43-5.96) and Me salicylate (rOAV: 2.15 – 2.50). Furthermore, the partial least squares (PLS) model indicated that geraniol, linalool, and Me salicylate benefited from the reservation of floral flavor of Keemun aroma characteristic of KBT. The findings presented in this thesis add to our understanding of KBT at different grades.

Food Chemistry published new progress about 90-64-2. 90-64-2 belongs to alcohols-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Alcohol,Natural product, name is 2-Hydroxy-2-phenylacetic acid, and the molecular formula is C11H8N2O2, Synthetic Route of 90-64-2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Sun, Guang-Ri published the artcileCleavage of arylalkylsilanes by sodium amide in liquid ammonia, Product Details of C9H22OSi, the publication is Synlett (2000), 619-622, database is CAplus.

The aryl carbon-silicon bonds in arylalkyl monosilanes have been cleaved by sodium amide in liquid ammonia. Sub-stoichiometric amounts of amide effect complete cleavage of the aryl anion. Reactions were complete in just a few minutes at room temperature except when bulky alkyl groups are present (eg. triisopropylphenylsilane). In dialkyldiarylsilanes both aryl functions were rapidly cleaved with little selectivity when the aryl groups had different substituents. The influence of metallic cations was important (NaNH₂, KNH₂ >> LiNH₂ > Ca(NH₂)₂). Solvent and temperature were also studied.

Synlett published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C9H8O4, Product Details of C9H22OSi.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Cui, Lei published the artcileExperimental study on multi-component corrosion inhibitor for steel bar in chloride environment, SDS of cas: 122-20-3, the publication is Construction and Building Materials (2021), 125533, database is CAplus.

This paper investigates one type of multi-component corrosion inhibitor for steel bars in chloride environment. Triethanolamine (TEA), tri-isopropanolamine (TIPA), sodium monofluorophos-phate (MFP) and sodium molybdate (T-4) were proportioned to prepare this multi-component corrosion inhibitor. Corrosion behavior of steel bar was evaluated using the polarization curve, electrochem. impedance spectroscopy (EIS) and SEM (SEM). The polarization curves were fitted using the adsorption isotherm models. Exptl. results indicated that the steel bar corrosion in chloride solution can be reduced by the addition of either organic or inorganic corrosion inhibitors. This is attributed to the fact that organic corrosion inhibitor can form an adsorption film on the steel bar surface and inorganic corrosion inhibitor abates electrochem. reaction of steel bars. Compared to single component corrosion inhibitors, the corrosion rate of steel bars in simulated pore solution was significantly restrained by the multi-component corrosion inhibitor. The adsorption of multi-component corrosion inhibitor on the surface of steel bar can significantly reinforce the passive film by means of phys. (organic) or chem. (inorganic) process. For all the investigated corrosion inhibitors, the adsorption isotherms were in good agreement with exptl. results. The EIS result and equivalent electrochem. circuit confirmed the chem. reaction and phys. adsorption process of the multi-component corrosion inhibitor. Therefore, the chloride induced corrosion of steel bars can be effectively controlled by the multi-component corrosion inhibitor.

Construction and Building Materials published new progress about 122-20-3. 122-20-3 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment, name is Triisopropanolamine, and the molecular formula is C9H21NO3, SDS of cas: 122-20-3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Jiang, Minghui published the artcileInhibition effect of different corrosion inhibitors on steel bars corrosion and improvement effect after double doped, Application In Synthesis of 122-20-3, the publication is Science Journal of Chemistry (2021), 9(4), 105-112, database is CAplus.

Reinforced concrete structures are easily corroded in the Salt Lake areas of China, especially in harsh environmental circumstance, such as freezing-thawing cycles, wetting-dry, et al, thus causing a lot of damage problems (concrete deterioration and steel bars corrosion). This research investigation was a research study which was to solve the corrosion problem of reinforced concrete structures under the chloride environmental circumstance through the electrochem. performance and mech. properties test of the reinforced mortar specimens, the effect of single or compound doping of two organic and two inorganic corrosion inhibitors to the electrode potential, electrochem. impedance spectroscopy and mech. properties of the reinforced mortar were investigated. The exptl. conclusion demonstrated that the organic or inorganic corrosion inhibitors after single and compound doping showed some degree influence on the electrode potential and mech. properties of the reinforced mortar specimens. Meanwhile, when the ratio of triethanolamine (TEA):triisopropanolamine (TIPA) was 7:3, sodium monofluorophosphate (MFP):sodium molybdate was 5:5, the compressive strength and flexural strength of mortar after curing for 28 days were greater than 90, it indicated that these proportions showed the best corrosion resistance performance of steel bars. Therefore, these proportions of corrosion inhibitors could be used in reinforced concrete structures. The significant was that these results could provide theor. guidance and tech. basis for the study of corrosion damage of reinforced concrete structures in the future.

Science Journal of Chemistry published new progress about 122-20-3. 122-20-3 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment, name is Triisopropanolamine, and the molecular formula is C9H21NO3, Application In Synthesis of 122-20-3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Cheng, Qiuhong published the artcileEutectogels as Matrices to Manipulate Supramolecular Chirality and Circularly Polarized Luminescence, Product Details of C8H8O3, the publication is ACS Nano (2022), 16(4), 6825-6834, database is CAplus and MEDLINE.

The occurrence and manipulation of supramol. chirality in deep eutectic solvents (DESs) was explored. Transfer from inherent chiral DES to solutes in either aggregated or monomeric building units is blocked. The chiral assembly of π-conjugated amino acids was realized. Compared to aqueous media, self-assembly in DES hinders the spontaneous structural and chirality evolution that benefit from efficient solvation, where the π-conjugated amino acids were involved as H bonding donors. DES performs as a dye-friendly matrix to afford chiroptical eutectogels with tunable circularly polarized luminescence, whereby a large dissymmetry g-factor of ≤0.015 was realized. DES behaves as feasible and flexible solvents to fabricate and stabilize functional soft chiral self-assemblies with controllable chiroptical properties.

ACS Nano published new progress about 90-64-2. 90-64-2 belongs to alcohols-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Alcohol,Natural product, name is 2-Hydroxy-2-phenylacetic acid, and the molecular formula is C8H8O3, Product Details of C8H8O3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts