Tag: M.W=100-150

Qian, Heng-Yu published the artcile< Synthesis, crystal structures, and antibacterial activity of new tetranuclear zinc(II) complexes with schiff base ligands>, Formula: C7H9NO, the main research area is zinc complex Schiff base ligand crystal structure antibacterial activity.

Two new tetranuclear zinc(II) complexes, [Zn4(L1)2(μ2-η1:η1-CH3COO)4(μ1,1-N3)2] (1) and [Zn4(L2)4(CH3CH2OH) (H2O)] (2), where L1 and L2 are the deprotonated forms of 4-fluoro-2-((pyridin-2-ylmethylimino)methyl)phenol (HL1) and 4-fluoro-2-((2-(hydroxymethyl)phenylimino)methyl)phenol (H2L2), have been synthesized and characterized by elemental anal., IR and UV-vis spectroscopy, and single crystal X-ray diffraction. X-ray crystal structural study indicated that the distances between the adjacent Zn atoms are 3.160(1)-3.353(1) Å in 1 and 3.005(1)-3.168(1) Å in 2. All zinc atoms in 1 are pentacoordinated in trigonal bipyramidal geometry, and those in 2 are in square pyramidal and octahedral geometry. The complexes and the Schiff bases were assayed for antibacterial activities against three Gram-pos. bacterial strains (B. subtilis, S. aureus, and St. faecalis) and three Gram-neg. bacterial strains (E. coli, P. aeruginosa, and E. cloacae) by MTT method.

Acta Chimica Slovenica published new progress about Antibacterial agents. 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Formula: C7H9NO.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ling, Xiujun; Wilcox, Craig S. published the artcile< A Molecular Torsion Balance Study: A Nearby Anionic Group Exerts Little Influence on Hydrophobic Interactions between Nonpolar Surfaces>, Reference of 3685-27-6, the main research area is mol torsion balance folding free energy; hydrophobic interaction; lipophilicity; non-covalent interactions; polarity; protein folding.

Polar groups have a solvent ordering effect on water and therefore may affect hydrophobic binding energies for nearby lipophilic surfaces. This would mean that determinations of excess surface free energy association energies require consideration of nearby polar functional groups. This paper reports results of a study to measure this possible effect. It was concluded from the models used here that an anionic polar group nearby a hydrophobic surface has little or no effect on the magnitude of hydrophobic association

Chemistry – A European Journal published new progress about Biaryls Role: PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 3685-27-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H14O2, Reference of 3685-27-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhong, Yuanhai; Zhou, Taigang; Zhang, Zhuohua; Chang, Ruiqing published the artcile< Copper-Catalyzed Transfer Hydrogenation of N-Heteroaromatics with an Oxazaborolidine Complex>, Category: alcohols-buliding-blocks, the main research area is quinoline hydrogenation oxaborolidine borane complex copper catalyst; tetrahydroquinoline preparation transfer hydrogenation quinoline oxaborolidine borane complex.

Quinolines, quinoxalines, acridine and 1,10-phenanthroline were hydrogenated at the heterocyclic ring by borane-oxaborolidine complex, prepared in situ from ethanolamine and BH3·THF, giving tetrahydro-derivatives; the reaction is catalyzed by copper(II) and copper(I) salts. The first time use of the oxazaborolidine complex in transfer hydrogenation, was accomplished. A general and efficient method for copper-catalyzed transfer hydrogenation of a variety N-heteroaromatics with oxazaborolidine-BH3 complex under mild reaction conditions afforded the corresponding hydrogenated products in up to 96% yields. Mechanistic studies indicate that the hydrogen source originated from water and borane that coordinate with the nitrogen atom of oxazaborolidine. Accordingly, a plausible mechanism for this reaction was proposed. This method was successfully used in the key step synthesis of natural products (±)-Angustureine and (±)-Galipinine in three steps.

ACS Omega published new progress about Amino alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Takojima, Kaoru; Saito, Tatsuya; Vevert, Cedric; Ladelta, Viko; Bilalis, Panayiotis; Watanabe, Jun; Hatanaka, Shintaro; Konno, Takashi; Yamamoto, Takuya; Tajima, Kenji; Hadjichristidis, Nikos; Isono, Takuya; Satoh, Toshifumi published the artcile< Facile synthesis of poly(trimethylene carbonate) by alkali metal carboxylate-catalyzed ring-opening polymerization>, Product Details of C9H8O, the main research area is trimethylene carbonate ROP alkali metal acetate catalyst green chem.

Abstract: Alkali metal carboxylates, including sodium acetate, sodium benzoate, and sodium sorbate, which are all readily available and widely used as food additives, were found to promote the ring-opening polymerization (ROP) of trimethylene carbonate (TMC) to produce poly(trimethylene carbonate) (PTMC). The sodium acetate-catalyzed ROP of TMC proceeded in the presence of an alc. initiator under solvent-free conditions at 70 °C, even at very low catalyst loadings of 0.01-0.0001 mol%. The controlled nature of this ROP system enabled the synthesis of PTMCs with predicted mol. weights ranging from 2400 to 11 700 g mol-1 and narrow dispersities (∼1.23). Importantly, ROP is initiated by an alc. initiator, allowing PTMC production with desired functional groups, such as azido, alkyne, and methacrylate groups, at the α-chain end. Furthermore, the poly(L-lactic acid)-b-PTMC-b-poly(L-lactic acid) triblock copolymer, a biodegradable thermoplastic elastomer, was successfully synthesized in one pot via the sodium acetate-catalyzed ring-opening block copolymerization of TMC and L-lactide with a 1,3-propanediol initiator.

Polymer Journal (Tokyo, Japan) published new progress about Biodegradable materials. 10602-04-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C9H8O, Product Details of C9H8O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ansari, Arshad J.; Yadav, Ayushi; Mukherjee, Anirban; Sathish, Elagandhula; Nagesh, Kommu; Singh, Ritesh published the artcile< Metal free amination of congested and functionalized alkyl bromides at room temperature>, SDS of cas: 5344-90-1, the main research area is aryl amine preparation; bromoamide aromatic heteroaromatic amine amination; benzodiazepine preparation.

The authors report a highly facile and unprecedented approach to synthesize congested N-(hetero)aryl amines, e.g., 4-NCC6H4NNHCMe2CONHOBn, en route to α-amino acid amides using α-bromoamides as alkylating agents under mild reaction conditions (room temperature). The involvement of aza-oxyallyl cations as alkylating agents is the hallmark of this reaction. This method was readily adapted for the rapid synthesis of coveted 1,4-benzodiazepine-3,5-diones I [R = R1 = H, MeO, R2 = OBn; R = R1 = R2 = H; R = R1 = MeO, R2 = H; R = H, R1 = Cl, R2 = OBn].

Chemical Communications (Cambridge, United Kingdom) published new progress about Amides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, SDS of cas: 5344-90-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Tan, Zhenda; Ci, Chenggang; Yang, Jian; Wu, Yang; Cao, Liang; Jiang, Huanfeng; Zhang, Min published the artcile< Catalytic Conversion of N-Heteroaromatics to Functionalized Arylamines by Merging Hydrogen Transfer and Selective Coupling>, HPLC of Formula: 5344-90-1, the main research area is azaarene alkyl bromide amino arylmethanol ruthenium hydrogen transfer coupling; alkylaminoaryl methylazaarene preparation chemoselective.

A ruthenium-catalyzed deconstruction of N-heteroaromatics to functionalized arylamines with 2-aminoaryl methanols via hydrogen transfer and selective coupling was reported. The reaction was achieved via sequential functionalization of the β and α-sites of the initially formed N-heteroarenium salts followed by a C-N cleavage, proceeding with the striking features of broad substrate scope, excellent functional groups tolerance, high chemoselectivity and atom-efficiency, and applicable for streamline synthesis of some biomedical mols. The strategy utilized will pave the avenues for further development of catalytic transformations of inert organo-systems to functional frameworks.

ACS Catalysis published new progress about Amino alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, HPLC of Formula: 5344-90-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ubeda, Cristina; Kania-Zelada, Ingeborg; del Barrio-Galan, Ruben; Medel-Maraboli, Marcela; Gil, Mariona; Pena-Neira, Alvaro published the artcile< Study of the changes in volatile compounds, aroma and sensory attributes during the production process of sparkling wine by traditional method>, Application In Synthesis of 104-76-7, the main research area is sparkling wine aroma sensory property volatile compound; Aging; Impact aroma compounds; Olfactometry; País grape variety; Sensory analysis; Volatile compounds; sparkling wine.

One of the strongest factors that affects the volatile profile of sparkling wine is the winemaking process. Here we focus on determining the effects of the second fermentation and aging on lees of sparkling wine from Pais grape variety combining different anal. techniques for the first time in sparkling wine: gas chromatog./mass spectrometry/olfactometry and sensorial anal. During the second fermentation and aging, there was a significant loss of esters that might be related to the adsorption on lees and ester volatility and chem. hydrolysis. The concentration of several compounds such as some esters (di-Et succinate, Et lactate, and Et isovalerate) increased during aging and could be used as aging markers. Vitispiranes were identified as the best norisoprenoids aging markers for young sparkling wines (12 mo of aging). Also, PCA showed that time of aging on lees affected mostly esters and terpenes. On the other hand, the diminution of fruity/floral impact odorants during aging was not perceived in sensorial trials. Our results suggest that the responsibility for fruity/floral nuances in sparkling wine might reside in a few high-impact aromatic compounds, such as Et isobutyrate, isoamyl acetate, Et hexanoate, β-phenylethanol and di-Et succinate.

Food Research International published new progress about Acids Role: BSU (Biological Study, Unclassified), PUR (Purification or Recovery), BIOL (Biological Study), PREP (Preparation). 104-76-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H18O, Application In Synthesis of 104-76-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Han, Mai; Han, Yuanyuan; Yan, Houchun; Gui, Huanhuan; Sun, Weizhen; Li, Qingsong published the artcile< Liquid-liquid equilibrium for ternary systems of 2,2,2-trifluoroethanol, water and different extractants at 303.2 K>, Category: alcohols-buliding-blocks, the main research area is extractant liquid equilibrium ternary system separation.

2,2,2-Trifluoroethanol (TFE) is used more and more widely in industry, but there are few reports on its separation at present. The purpose of this work is to explore the feasibility of separating 2,2,2-trifluoroethanol from aqueous solution using different extractants, as isopentanol, 2-Ethyl-1-hexanol, n-Pr acetate, and dichloromethane. The liquid-liquid equilibrium data of TFE + water +{isopentanol or 2-ethyl-1-hexanol or Pr acetate or dichloromethane} at standard pressure and 303.2 K were measured. The estimated partition coefficient (D) and separation factor (S) of TFE are higher than 1. Meanwhile, Othmer-Tobias and Hand’s empirical equations verified the exptl. data’s consistency, and the squares of its linear correlation are all greater than 0.99. The NRTL and UNIQUAC activity coefficient models were used to correlate the exptl. data, and different model parameters were obtained by regression. After comparing the calculated values of the model with the exptl. data, it was found that the root means square deviation (RMSD%) was less than 0.34%, which indicate that both models have a reasonable correlation with the exptl. data of the ternary system and can accurately predict the exptl. data.

Journal of Chemical Thermodynamics published new progress about Equilibrium. 104-76-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H18O, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chan, Kelvin S. L.; Fu, Hai-Yan; Yu, Jin-Quan published the artcile< Palladium(II)-Catalyzed Highly Enantioselective C-H Arylation of Cyclopropylmethylamines>, Recommanded Product: (1-(Aminomethyl)cyclopropyl)methanol, the main research area is cyclopropylmethylamine CH activation arylation palladium catalyst enantioselectivity diastereoselectivity.

C-H arylation via a Pd(II)/Pd(IV) catalytic cycle has been one of the most extensively studied C-H activation reactions since the 1990s. Despite the rapid development of this reaction in the past two decades, an enantioselective version has not been reported to date. Herein, we report a Pd(II)-catalyzed highly enantioselective (up to 99.5% ee) arylation of cyclopropyl C-H bonds with aryl iodides using mono-N-protected amino acid (MPAA) ligands, providing a new route for the preparation of chiral cis-aryl-cyclopropylmethylamines, e.g., I [R1 = H, Me, CH2Ph, Ph, C6H3F2-2,6, CH2OSiMe2CMe3, CO2Me]. The enantiocontrol is also shown to override the diastereoselectivity of chiral substrates.

Journal of the American Chemical Society published new progress about Amino acids Role: CAT (Catalyst Use), USES (Uses) (mono-N-protected, chiral ligands for arylation catalysts). 45434-02-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C5H11NO, Recommanded Product: (1-(Aminomethyl)cyclopropyl)methanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Liu, Xu-Teng; Han, Xue-Yu; Wu, Yue; Sun, Ying-Ying; Gao, Li; Huang, Zhuo; Zhang, Qing-Wei published the artcile< Ni-Catalyzed Asymmetric Hydrophosphination of Unactivated Alkynes>, Category: alcohols-buliding-blocks, the main research area is nickel catalyzed asym regioselective enantioselective hydrophosphination unactivated alkyne; phosphorus stereogenic tertiary phosphine preparation reaction; crystal mol structure alkenyl phosphine borane sulfide ruthenium platinum.

The practical synthesis of P-stereogenic tertiary phosphines, which have wide applications in asym. catalysis, materials, and pharmaceutical chem., represents a significant challenge. A regio- and enantioselective hydrophosphination using cheap and ubiquitous alkynes catalyzed by a nickel complex was designed, in which the toxic and air-sensitive secondary phosphines were prepared in situ from bench-stable secondary phosphine oxides. This methodol. has been demonstrated with unprecedented substrate scope and functional group compatibility to afford electronically and structurally diversified P(III) compounds The products could be easily converted into various precursors of bidentate ligands and organocatalysts, as well as a variety of transition-metal complexes containing both P- and metal-stereogenic centers.

Journal of the American Chemical Society published new progress about Alkynes Role: RCT (Reactant), RACT (Reactant or Reagent) (unactivated). 10602-04-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C9H8O, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts