Tag: M.W=100-150

Das, Jagadish; Vellakkaran, Mari; Banerjee, Debasis published the artcile< Nickel-Catalyzed Alkylation of Ketone Enolates: Synthesis of Monoselective Linear Ketones>, Electric Literature of 5344-90-1, the main research area is ketone alc nickel monoselective alkylation catalyst; linear ketone preparation green chem.

Herein we have developed a Ni-catalyzed protocol for the synthesis of linear ketones. Aryl, alkyl, and heteroaryl ketones as well as alcs. yielded the monoselective ketones in up to 90% yield. The catalytic protocol was successfully applied in to a gram-scale synthesis. For a practical utility, applications of a steroid derivative, oleyl alc., and naproxen alc. were employed. Preliminary catalytic investigations involving the isolation of a Ni intermediate and defined Ni-H species as well as a series of deuterium-labeling experiments were performed.

Journal of Organic Chemistry published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Electric Literature of 5344-90-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Bains, Amreen K.; Singh, Vikramjeet; Adhikari, Debashis published the artcile< Homogeneous Nickel-Catalyzed Sustainable Synthesis of Quinoline and Quinoxaline under Aerobic Conditions>, Application In Synthesis of 5344-90-1, the main research area is amine alc nickel catalyst dehydrogenative coupling green; quinoline preparation; quinoxaline preparation.

Dehydrogenative coupling-based reactions have emerged as an efficient route toward the synthesis of a plethora of heterocyclic rings. Herein, we report an efficacious, nickel-catalyzed synthesis of two important heterocycles such as quinoline and quinoxaline. The catalyst is molecularly defined, is phosphine-free, and can operate at a mild reaction temperature of 80°C. Both the heterocycles can be easily assembled via double dehydrogenative coupling, starting from 2-aminobenzyl alc./1-phenylethanol and diamine/diol, resp., in a shorter span of reaction time. This environmentally benign synthetic protocol employing an inexpensive catalyst can rival many other transition-metal systems that have been developed for the fabrication of two putative heterocycles. Mechanistically, the dehydrogenation of secondary alc. follows clean pseudo-first-order kinetics and exhibits a sizable kinetic isotope effect. Intriguingly, this catalyst provides an example of storing the trapped hydrogen in the ligand backbone, avoiding metal-hydride formation. Easy regeneration of the oxidized form of the catalyst under aerobic/O2 oxidation makes this protocol eco-friendly and easy to handle.

Journal of Organic Chemistry published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Application In Synthesis of 5344-90-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wen, Rongxin; Hu, Yingying; Zhang, Lang; Wang, Yan; Chen, Qian; Kong, Baohua published the artcile< Effect of NaCl substitutes on lipid and protein oxidation and flavor development of Harbin dry sausage>, Electric Literature of 104-76-7, the main research area is sodium chloride dry sausage flavor lipid protein oxidation; Harbin dry sausage; Lipid oxidation; Protein oxidation; Sodium substitutes; Volatile compound analysis.

The effects of partially replacing NaCl with sodium substitutes (SS) on the lipid and protein oxidation and flavor development of Harbin dry sausage was investigated. There were three salt formulations, including a control (100% NaCl), NaCl partially substituted with KCl (SS1) (70% NaCl and 30% KCl), and NaCl partially substituted with KCl combined with other components (SS2) (70% NaCl, 20% KCl, 4% lysine, 1% alanine, 0.5% citric acid, 1% Ca-lactate and 3.5% maltodextrin). The levels of lipid and protein oxidation increased in all sausages during fermentation (P < 0.05). In addition, lower oxidation of lipids and proteins were found in the SS2 treatment (P < 0.05) due to the lower NaCl concentration The SS, especially the SS2, promoted the formation of volatile compounds originated from carbohydrate and amino acid metabolism, β-lipid oxidation and esterification; however, this substitute inhibited the formation of volatile compounds originated from lipid autoxidation (P < 0.05). Overall, SS2 could improve the flavor development of Harbin dry sausage and reduce NaCl by 30%. Meat Science published new progress about Carbohydrates Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 104-76-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H18O, Electric Literature of 104-76-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Tingting; Fan, Xiaotong; Xu, Jiayun; Li, Ruyu; Yan, Xu; Liu, Shengda; Jiang, Xiaojia; Li, Fei; Liu, Junqiu published the artcile< Giant Proteinosomes As Scaffolds for Light Harvesting>, Name: 2-Ethylhexan-1-ol, the main research area is giant proteinosome arsenic scaffold harvesting.

Based on an interfacial assembly strategy, a giant proteinosome was successfully fabricated by using protein-surfactant as building blocks, which formed a thin protein layer as a membrane. This approach of making protein assemblies was very facile, and it was very convenient to remove the templates of oil and get water-filled proteinosomes by dialysis. Through modifying acceptor and donor chromophores on the protein monomers, an efficient artificial light-harvesting system was successfully fabricated on the proteinosome, which was a scaffold for efficient light harvesting. Furthermore, the on-off switchable energy transfer was realized by protein folding and unfolding. The efficient artificial light-harvesting systems we designed as the potential platforms could be utilized for biomaterials.

ACS Macro Letters published new progress about Bovine serum albumin Role: BUU (Biological Use, Unclassified), PEP (Physical, Engineering or Chemical Process), SPN (Synthetic Preparation), TEM (Technical or Engineered Material Use), BIOL (Biological Study), USES (Uses), PROC (Process), PREP (Preparation) (complexes with rhodamine B or FTIC). 104-76-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H18O, Name: 2-Ethylhexan-1-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chevella, Durgaiah; Macharla, Arun Kumar; Kodumuri, Srujana; Banothu, Rammurthy; Gajula, Krishna Sai; Amrutham, Vasu; Gennadievna, Grigor’eva Nellya; Nama, Narender published the artcile< Synthesis of internal olefins by direct coupling of alcohols and olefins over Moβ zeolite>, Formula: C8H9FO, the main research area is reusable molybdenum zeolite preparation thermal stability crystallinity; olefin aryl alc reusable zeolite catalyst dehydrative cross coupling; internal olefin diastereoselective regioselective preparation green chem.

An efficient and novel Moβ zeolite catalyzed sp2-sp3 C-C bond development reaction over the direct coupling of alcs. and alkenes was performed in solvent free environment. The current method gave an attractive access to a wide variety of polysubstituted alkenes in good to excellent yields. The Moβ zeolite was effectively reused for up to 5 successive cycles.

Catalysis Communications published new progress about Acidity. 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Formula: C8H9FO.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Huan; Yin, Dazhen; You, Shijun; Zheng, Wandong; Wei, Shen published the artcile< Experimental investigation of heat and mass transfer in a LiBr-H2O solution falling film absorber on horizontal tubes: Comprehensive effects of tube types and surfactants>, Computed Properties of 104-76-7, the main research area is surfactant lithium bromide water solution falling film absorber tube.

This paper studied the effects of various surface geometries and surfactants on the LiBr-H2O solution falling film absorption, and the heat and mass transfer during the absorption process. Three different tubes (plain tube, floral tube and floral finned tube) were tested for the LiBr-H2O solution with two different surfactants (2-Ethyl-1-hexanol and 1-Octanol). The results indicate that the heat and mass transfer coefficients of each tube gradually decrease with solution falling down the tube bundle. It is also showed that the effect of surfactant on heat and mass transfer is obviously greater than that of tube surface geometry. Furthermore, with 2-Ethyl-1-hexanol as the surfactant, the heat and mass transfer can be improved by 400% and 350%, resp. The results of comparative study show that the heat and mass transfer performance of floral tubes with 2-Ethyl-1-hexanol is more stable and reliable than others.

Applied Thermal Engineering published new progress about Heat transfer. 104-76-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H18O, Computed Properties of 104-76-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Itoga, Moeko; Yamanishi, Masako; Udagawa, Taro; Kobayashi, Ayane; Maekawa, Keiko; Takemoto, Yoshiji; Naka, Hiroshi published the artcile< Iridium-catalyzed α-selective deuteration of alcohols>, Electric Literature of 10602-04-7, the main research area is iridium bipyridonate complex preparation DFT; deuterated alc chemoselective preparation; alc deuteration iridium bipyridonate complex catalyst.

The α-selective, iridium(III)-bipyridonate-catalyzed hydrogen(H)/deuterium(D) isotope exchange of alcs. using deuterium oxide (D2O) as the primary deuterium source to afford deuterated alcs. RCD2OH [R = Ph, 2-MeC6H4, 4-FC6H4, etc.], R1DCOHR2 [R1 = Ph, 4-ClC6H4, 4-BrC6H4, etc.; R2 = Me, cyclopropyl, Ph] was reported. This method enabled the direct, chemoselective deuteration of primary and secondary alcs. under basic or neutral conditions without being affected by coordinative functional groups such as imidazole and tetrazole. Successful substrates for deuterium labeling include the pharmaceuticals losartan potassium, rapidosept, guaifenesin and diprophylline. The deuterated losartan potassium showedhigher stability toward the metabolism by CYP2C9 than the protiated analog. Kinetic and DFT studies indicated that the direct deuteration proceeded through dehydrogenation of alc. to the carbonyl intermediate, conversion of [IrIII-H] to [IrIII-D] with D2O, and deuteration of the carbonyl intermediate to give the α-deuterated products.

Chemical Science published new progress about Alcohols Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 10602-04-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C9H8O, Electric Literature of 10602-04-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Guoqi; Li, Sihan; Zeng, Haisu; Zheng, Shengping; Neary, Michelle C. published the artcile< Diplumbane-catalysed solvent- and additive-free hydroboration of ketones and aldehydes>, Synthetic Route of 403-41-8, the main research area is alc preparation chemoselective; ketone aldehyde pinacolborane hydroboration diplumbane catalyst.

A new diplumbane, namely [Pb(CH2SiMe3)3]2, was synthesized and structurally characterized. This group 14 element compound was found to catalyze the hydroboration of ketones R1C(O)R2 (R1 = Ph, 4-fluorophenyl, naphthalen-2-yl, pyridin-3-yl, cyclohexyl, etc.; R2 = H, Me, cyclopropyl, 2-phenylethyl) and aldehydes R3CHO (R3 = Ph, 4-chlorophenyl, 2H-1,3-benzodioxol-5-yl, 2-(methylsulfanyl)phenyl, etc.) under mild conditions without the use of additives and solvents, leading to the synthesis of a range of alcs. R1CH(OH)R2/R3CH2OH in high yields after hydrolysis.

RSC Advances published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Synthetic Route of 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Huang, Xu-Hui; Qi, Li-Bo; Fu, Bao-Shang; Chen, Zeng-Hui; Zhang, Yu-Ying; Du, Ming; Dong, Xiu-Ping; Zhu, Bei-Wei; Qin, Lei published the artcile< Flavor formation in different production steps during the processing of cold-smoked Spanish mackerel>, Safety of 2-Ethylhexan-1-ol, the main research area is mackerel flavor smoking; Cold smoking; Flavor formation; GC–MS; Mackerel; P&T; e-Nose.

This study aimed to determine the changes in the flavor profile during different operating units when making cold-smoked Spanish mackerel. Sensory evaluation and instrumental anal. of tenderness were applied to optimize the processing parameters. For the overall odor perception, distinct odor among fresh and processed samples could be distinguished using electronic nose (e-Nose). Purge-and-trap (P&T) extraction combined with gas chromatog.-mass spectrometry (GC-MS) was used to identify volatile compounds Alcs. were the major volatiles in Spanish mackerel over the whole processing, while 2-butanol was found in the highest concentration Curing was an effective way to remove fishy odor. Drying decreased the concentration of volatiles, especially sulfur compounds Odor formation in cold-smoked mackerel could be divided into four steps (curing, drying, cold smoking and heating) as a result of partial least squares discriminant anal. (PLS-DA).

Food Chemistry published new progress about Flavor. 104-76-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H18O, Safety of 2-Ethylhexan-1-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Patra, Kamaless; Laskar, Roshayed Ali; Nath, Anubhav; Bera, Jitendra K. published the artcile< A Protic Mn(I) Complex Based on a Naphthyridine-N-oxide Scaffold: Protonation/Deprotonation Studies and Catalytic Applications for Alkylation of Ketones>, Application of C7H9NO, the main research area is cyclometalated manganese naphthyridine oxide carbonyl complex preparation alkylation catalyst; crystal structure cyclometalated manganese naphthyridine oxide carbonyl complex; mol structure cyclometalated manganese naphthyridine oxide carbonyl complex; alkylation ketone primary alc manganese naphthyridine oxide catalyst.

A Mn(I) complex (1) bearing a proton responsive hydroxy unit on 1,8-naphthyridine-N-oxide scaffold (L1H) was synthesized. The mol. structure of 1 revealed the lactim form of the ligand. The corresponding deprotonated lactam complexes [18-C-6-K·2] and 3 were prepared and structurally characterized. The acid-base equilibrium between the lactim and lactam forms was studied by 1H NMR and UV-visible spectra. The catalytic efficiency of 1 was evaluated by performing α-alkylation reaction of ketones with primary alcs. The scope of the α-alkylation reaction is broad in terms of both ketones and alcs. The efficacy of the protic catalyst is demonstrated in the alkylation of the bioactive steroids progesterone and pregnenolone. A controlled catalyst [Mn(L2)(CO)3Br] (4), which is structurally similar to 1 but devoid of the proton responsive hydroxy unit, shows significantly reduced catalytic efficiency validating the crucial role of the hydroxy functionality in 1. Kinetic study, control reactions, and D labeling experiments were conducted to gain mechanistic insights.

Organometallics published new progress about Alkylation. 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Application of C7H9NO.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts