Tag: M.W=100-150

Ye, Danfeng; Liu, Zhiyuan; Sessler, Jonathan L.; Lei, Chuanhu published the artcile< Base-free oxidation of alcohols enabled by nickel(II)-catalyzed transfer dehydrogenation>, Related Products of 403-41-8, the main research area is ketone preparation; alc nickel catalyst transfer dehydrogenation oxidation.

An efficient nickel(II)-catalyzed transfer dehydrogenation oxidation of alcs. was reported that relies on cyclohexanone as the formal oxidant and does not require the use of an external base. The synthetic utility of this protocol was demonstrated via the facile oxidation of structurally complicated natural products.

Chemical Communications (Cambridge, United Kingdom) published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Related Products of 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Chong; Hu, Bowen; Chen, Dafa; Xia, Haiping published the artcile< Manganese(I)-Catalyzed Transfer Hydrogenation and Acceptorless Dehydrogenative Condensation: Promotional Influence of the Uncoordinated N-Heterocycle>, Category: alcohols-buliding-blocks, the main research area is manganese pyridylquinoline pyridylnaphthyridine preparation catalyst transfer hydrogenation dehydrogenative condensation; transfer hydrogenation ketone aldehyde catalyzed manganese carbonyl pyridylquinoline pyridylnaphthyridine; dehydrogenative condensation alc ketone catalyzed manganese carbonyl pyridylnaphthyridine; crystal structure manganese carbonyl bipyridinol complex.

The four bidentate Mn(I) complexes [(C5H4N-C5H3N-OH)Mn(CO)3Br] (1), [(C9H6N-C5H3N-OH)Mn(CO)3Br] (2), [(C8H5N2-C5H3N-OH)Mn(CO)3Br] (3), and [(C8H5N2-C5H3N-OCH3)Mn(CO)3Br] (4) were synthesized. These complexes were tested as catalysts for the transfer hydrogenation of ketones, and 3 showed the highest activity. The reactions proceeded well with 0.5 mol % of catalyst loading and 20 mol % of t-BuOK at 85° for 24 h. Also, 3 was also used as a catalyst for the synthesis of primary alcs. via transfer hydrogenation of aldehydes and the synthesis of 1,2-disubstituted benzimidazoles and quinolines via acceptorless dehydrogenative condensations.

Organometallics published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Abubakar, Samaila; Bala, Muhammad D. published the artcile< Transfer Hydrogenation of Ketones Catalyzed by Symmetric Imino-N-heterocyclic Carbene Co(III) Complexes>, Electric Literature of 403-41-8, the main research area is ketone imino NHC cobalt transfer hydrogenation catalyst; alc preparation.

The synthesis of new moisture-sensitive imine-functionalized N-heterocyclic carbene (NHC) precursor salts [1-(2-[(hydroxyl-benzylidene)-amino]-ethyl)-3-R-3H-imidazole-1-ium bromide; R = Me, Et, and benzyl] is reported. Subsequent deprotonation of precursor and coordination of the in situ generated NHC ligands to CoBr2 led to the isolation of air-stable six-coordinate Co(III) complexes, resp. All the salts and complexes were fully characterized. Single-crystal X-ray anal. of Co(III) complexes showed octahedral Co centers hexacoordinated to two NHC carbons, two imine nitrogen atoms, and two phenolate oxygens in the form [C~NÕ(Co3+)CÑÕ]. The complexes were used in the catalytic transfer hydrogenation (CTH) of a range of ketones in 2-propanol as the solvent and hydrogen donor. Based on a low catalyst concentration of 0.4 mol %, significant conversions in the range of 70-99% were recorded at high turnover frequencies up to 1635 h-1. A mechanism to account for the steps involved in the CTH of cyclohexanone by complex is proposed and supported by data from cyclic voltammetry, low-resolution mass spectrometry, UV, and IR spectroscopic techniques.

ACS Omega published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Electric Literature of 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Bains, Amreen K.; Singh, Vikramjeet; Adhikari, Debashis published the artcile< Homogeneous Nickel-Catalyzed Sustainable Synthesis of Quinoline and Quinoxaline under Aerobic Conditions>, Related Products of 403-41-8, the main research area is amine alc nickel catalyst dehydrogenative coupling green; quinoline preparation; quinoxaline preparation.

Dehydrogenative coupling-based reactions have emerged as an efficient route toward the synthesis of a plethora of heterocyclic rings. Herein, we report an efficacious, nickel-catalyzed synthesis of two important heterocycles such as quinoline and quinoxaline. The catalyst is molecularly defined, is phosphine-free, and can operate at a mild reaction temperature of 80°C. Both the heterocycles can be easily assembled via double dehydrogenative coupling, starting from 2-aminobenzyl alc./1-phenylethanol and diamine/diol, resp., in a shorter span of reaction time. This environmentally benign synthetic protocol employing an inexpensive catalyst can rival many other transition-metal systems that have been developed for the fabrication of two putative heterocycles. Mechanistically, the dehydrogenation of secondary alc. follows clean pseudo-first-order kinetics and exhibits a sizable kinetic isotope effect. Intriguingly, this catalyst provides an example of storing the trapped hydrogen in the ligand backbone, avoiding metal-hydride formation. Easy regeneration of the oxidized form of the catalyst under aerobic/O2 oxidation makes this protocol eco-friendly and easy to handle.

Journal of Organic Chemistry published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Related Products of 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Lan, Xiao-Bing; Ye, Zongren; Huang, Ming; Liu, Jiahao; Liu, Yan; Ke, Zhuofeng published the artcile< Nonbifunctional Outer-Sphere Strategy Achieved Highly Active α-Alkylation of Ketones with Alcohols by N-Heterocyclic Carbene Manganese (NHC-Mn)>, Synthetic Route of 5344-90-1, the main research area is ketone alc NHC manganese alkylation catalyst; alkylated ketone preparation; amino benzyl alc ketone NHC manganese Friedlander annulation catalyst; quinoline preparation.

The unusual nonbifunctional outer-sphere strategy was successfully utilized in developing an easily accessible N-heterocyclic carbene manganese (NHC-Mn) system for highly active α-alkylation of ketones with alcs. This system was efficient for a wide range of ketones and alcs. under mild reaction conditions, and also for the green synthesis of quinoline derivatives The direct outer-sphere mechanism and the high activity of the present system demonstrate the potential of nonbifunctional outer-sphere strategy in catalyst design for acceptorless dehydrogenative transformations.

Organic Letters published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Synthetic Route of 5344-90-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Martinez-Ferrate, Oriol; Chatterjee, Basujit; Werle, Christophe; Leitner, Walter published the artcile< Hydrosilylation of carbonyl and carboxyl groups catalysed by Mn(I) complexes bearing triazole ligands>, Recommanded Product: 1-(4-Fluorophenyl)ethyl Alcohol, the main research area is alc preparation; ketone ester carboxyl hydrosilylation manganese triazole ligand catalyst.

Manganese(I) complexes bearing triazole ligands are reported as catalysts for the hydrosilylation of carbonyl and carboxyl compounds The desired reaction proceeds readily at 80° within 3 h at catalyst loadings as low as 0.25 to 1 mol%. Hence, good to excellent yields of alcs. could be obtained for a wide range of substrates including ketones, esters, and carboxylic acids illustrating the versatility of the metal/ligand combination.

Catalysis Science & Technology published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Recommanded Product: 1-(4-Fluorophenyl)ethyl Alcohol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Bheeter, Linus P.; Henrion, Mickael; Brelot, Lydia; Darcel, Christophe; Chetcuti, Michael J.; Sortais, Jean-Baptiste; Ritleng, Vincent published the artcile< Hydrosilylation of aldehydes and ketones catalyzed by an N-heterocyclic carbene-nickel hydride complex under mild conditions>, Safety of (1-Methyl-1H-pyrrol-2-yl)methanol, the main research area is nitrogen heterocyclic carbene nickel hydride preparation mol crystal structure; aldehyde hydrosilylation nitrogen heterocyclic carbene nickel hydride complex catalyst; ketone hydrosilylation nitrogen heterocyclic carbene nickel hydride complex catalyst; alc preparation.

Half-sandwich N-heterocyclic carbene (NHC)-nickel complexes of the general formula [Ni(NHC)ClCp1] (Cp1 = Cp, Cp*) efficiently catalyze the hydrosilylation of aldehydes and ketones at room temperature in the presence of a catalytic amount of sodium triethylborohydride and thus join the fairly exclusive club of well-defined nickel(II) catalyst precursors for the hydrosilylation of carbonyl functionalities. Of notable interest is the isolation of an intermediate nickel hydride complex that proved to be the real catalyst precursor.

Advanced Synthesis & Catalysis published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 52160-51-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H9NO, Safety of (1-Methyl-1H-pyrrol-2-yl)methanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Ze-Shu; Chen, Yang-Bo; Wang, Kun; Xu, Zhou; Ye, Long-Wu published the artcile< One-pot synthesis of 2-hydroxymethylindoles via photoredox-catalyzed ketyl-ynamide coupling/1,3-allylic alcohol transposition>, SDS of cas: 5344-90-1, the main research area is benzoyl arylethynyl alkylsulfonamide iridium photocatalyst regioselective coupling reaction; hydroxymethylindole preparation.

An efficient visible-light-mediated ketyl-ynamide coupling by employing ynamides bearing alkyl sulfonyl substituents to deliver eneindolin-3-ols was developed. Subsequent 1,3-transposition of allylic alcs. in one pot was capable of synthesizing 2-hydroxymethylindoles in generally moderate to good yields. The synthetic utility of this protocol was also demonstrated by the facile and practical synthesis of two bioactive mols. The use of readily available substrates, a simple procedure and benign reaction conditions render this method a viable alternative for the synthesis of 2-hydroxymethylindoles.

Green Chemistry published new progress about Alkynes, aryl Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, SDS of cas: 5344-90-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kaithal, Akash; van Bonn, Pit; Hoelscher, Markus; Leitner, Walter published the artcile< Manganese(I)-Catalyzed β-Methylation of Alcohols using Methanol as C1 Source>, Synthetic Route of 403-41-8, the main research area is manganese catalyzed methylation biomass alc methanol solvent safety; alcohols; hydrogen borrowing; manganese catalysis; methanol; methylation.

Highly selective β-methylation of alcs. was achieved using an earth-abundant first row transition metal in the air stable mol. manganese complex [Mn(CO)2Br[HN(C2H4PiPr2)2]] (I) ([HN(C2H4PiPr2)2]=MACHO-iPr). The reaction requires only low loadings of I (0.5 mol %), methanolate as base and MeOH as methylation reagent as well as solvent. Various alcs. were β-methylated with very good selectivity (>99%) and excellent yield (up to 94%). Biomass derived aliphatic alcs. and diols were also selectively methylated on the β-position, opening a pathway to “”biohybrid”” mols. constructed entirely from non-fossil carbon. Mechanistic studies indicate that the reaction proceeds through a borrowing hydrogen pathway involving metal-ligand cooperation at the Mn-pincer complex. This transformation provides a convenient, economical, and environmentally benign pathway for the selective C-C bond formation with potential applications for the preparation of advanced biofuels, fine chems., and biol. active mols. Of note, safety advice is recommended for high-pressure experiments due to significant risk with procedures and in conjunction with the use of suitable equipment.

Angewandte Chemie, International Edition published new progress about Alcohols Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (biomass). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Synthetic Route of 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zheng, Jianxia; Darcel, Christophe; Sortais, Jean-Baptiste published the artcile< A convenient nickel-catalysed hydrosilylation of carbonyl derivatives>, Formula: C6H9NO, the main research area is aldehyde hydrosilylation reduction polymethylhydrosiloxane nickel; primary alc preparation; ketone hydrosilylation reduction polymethylhydrosiloxane nickel; secondary alc preparation; nickel hydrosilylation reduction catalyst; polymethylhydrosiloxane reducing agent.

Hydrosilylation of aldehydes and ketones catalyzed by nickel acetate and tricyclohexylphosphine as the catalytic system was demonstrated using polymethylhydrosiloxane as a cheap reducing reagent.

Catalysis Science & Technology published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 52160-51-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H9NO, Formula: C6H9NO.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts