Tag: M.W=100-150

Zhang, Jinli; Chen, Ling; Dong, Yibo; Yang, Jinchen; Wu, Yangjie published the artcile< A Cu2O/TBAB-promoted approach to synthesize heteroaromatic 2-amines via one-pot cyclization of aryl isothiocyanates with ortho-substituted amines in water>, Application of C7H9NO, the main research area is aryl isothiocyanate amine copper catalyst desulfurization dehydrogenative cyclization; heteroaromatic amine preparation green chem.

An efficient approach to synthesize heteroaromatic 2-amines from one-pot desulfurization/dehydrogenative cyclization of aryl isothiocyanates with ortho-substituted amines in water was developed. This approach tolerated a wide range of functional groups on the aromatic ring, providing a practical and environment-friendly process to synthesize heteroaromatic 2-amines in moderate to excellent yields. A plausible mechanism was proposed and the role of TBAB and Cu2O in the present strategy was suggested with the help of ESI mass spectrometry.

Organic & Biomolecular Chemistry published new progress about Amino alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Application of C7H9NO.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Magre, Marc; Paffenholz, Eva; Maity, Bholanath; Cavallo, Luigi; Rueping, Magnus published the artcile< Regiodivergent Hydroborative Ring Opening of Epoxides via Selective C-O Bond Activation>, Quality Control of 403-41-8, the main research area is secondary tertiary alc regiodivergent synthesis hydroborative ring opening epoxide.

A magnesium-catalyzed regiodivergent C-O bond cleavage protocol is presented. Readily available magnesium catalysts achieve the selective hydroboration of a wide range of epoxides and oxetanes yielding secondary and tertiary alcs. in excellent yields and regioselectivities. Exptl. mechanistic investigations and DFT calculations provide insight into the unexpected regiodivergence and explain the different mechanisms of the C-O bond activation and product formation.

Journal of the American Chemical Society published new progress about C-O bond activation. 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Quality Control of 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wei, Duo; Dorcet, Vincent; Darcel, Christophe; Sortais, Jean-Baptiste published the artcile< Synthesis of Quinolines Through Acceptorless Dehydrogenative Coupling Catalyzed by Rhenium PN(H)P Complexes>, Application In Synthesis of 403-41-8, the main research area is quinoline preparation green chem; aryl alc hydroxymethyl aniline dehydrogenative coupling rhenium catalyst; ketone hydroxymethyl aniline dehydrogenative coupling rhenium catalyst; nitrile hydroxymethyl aniline dehydrogenative coupling rhenium catalyst; annulation; dehydrogenative coupling; hydrogen borrowing; quinoline; rhenium.

The practical and sustainable synthesis of substituted quinolines I (R1 = C6H5, cyclopropyl, NH2, etc.; R2 = H, C6H5, CH3, etc.; R1R2 = (CH2)4, (CH2)6) and 5,6-dihydro-benzo[c]acridine was achieved through the annulation of 2-aminobenzyl alc. with various secondary alcs. R1CH(OH)CH2R2, ketones R1C(O)CH2R2, phenylacetaldehyde, or nitriles R2CH2CN, under hydrogen-borrowing conditions. Under the catalysis of well-defined rhenium complexes bearing tridentate diphosphinoamino ligands, the reaction proceeded efficiently (31 examples were isolated with yields up to 96%) for affording a variety of quinoline derivatives I and 5,6-dihydro-benzo[c]acridine.

ChemSusChem published new progress about Aromatic alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Application In Synthesis of 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Genc, Sertac; Gulcemal, Suleyman; Gunnaz, Salih; Cetinkaya, Bekir; Gulcemal, Derya published the artcile< Synthesis of α-Alkylated Ketones via Selective Epoxide Opening/Alkylation Reactions with Primary Alcohols>, Category: alcohols-buliding-blocks, the main research area is ketone alkyl preparation regioselective; alc primary epoxide opening alkylation reaction NHC iridium catalyst.

A new method for converting terminal epoxides I (R = Ph, naphthalen-2-yl, decyl, etc.) and primary alcs. R1CH2OH (R1 = hexyl, 2-aminophenyl, thiophen-2-yl, 3-ferrocenyl, etc.) into α-alkylated ketones RC(O)(CH2)2R1, 3,3′-(1,4-phenylene)bis(1-phenylpropan-1-one) and 2-phenylquinoline under borrowing hydrogen conditions is reported. The procedure involves a one-pot epoxide ring opening and alkylation via primary alcs. in the presence of an N-heterocyclic carbene iridium(I) catalyst, under aerobic conditions, with water as the side product.

Organic Letters published new progress about Alkylation catalysts, regioselective. 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Luna, F. Murilo T.; Salmin, Davi Costa; Santiago, Vanessa S.; Maia, Francisco J. N.; Silva, Francisco O. N.; Mazzetto, Selma E.; Cavalcante, Celio L. Jr. published the artcile< Oxidative stability of acylated and hydrogenated ricinoleates using synthetic and natural antioxidants>, Name: 2-Ethylhexan-1-ol, the main research area is acylated hydrogenated ricinoleate antioxidant thermo oxidative stability.

As increasing environmental policies constrains are imposed, the demand for biodegradable products also increases. Although vegetable oils present some properties that favor its use for formulation of a bio-based lubricant, its poor resistance to oxidation hinders its application as such. In this study, the thermo-oxidative stability of bio-based products was compared to petroleum-based lubricants and vegetable oils through the PetroOXY method. Chem. modifications in the ricinoleic acids were carried out using long-chain alcs. in esterification reactions. Acetates were obtained from ricinoleates with and without hydrogenation steps. Addnl., com. antioxidants and phenolic compounds (saturated and unsaturated cardanol) obtained from cashew nut shell liquid were added to the synthesized samples with higher induction times. The results show that the chem. modified bio-based products exhibited improved oxidative stability (up to 6 times) and depressed pour point (-42°C) when compared to pure castor oil. Overall, the addition of antioxidants increased from 6 to 20 times the oxidative stability of the bio-based products. Pr gallate and saturated cardanol showed higher efficiency for retarding the oxidative process of bio-based samples than the com. antioxidants.

Journal of Chemistry published new progress about Acetylation. 104-76-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H18O, Name: 2-Ethylhexan-1-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chen, Jian; Zhu, Shaolin published the artcile< Nickel-Catalyzed Multicomponent Coupling: Synthesis of α-Chiral Ketones by Reductive Hydrocarbonylation of Alkenes>, Recommanded Product: 1-(4-Fluorophenyl)ethyl Alcohol, the main research area is alpha ketone preparation regio chemo enantioselective; alkene benzyl chloride ethyl chloroformate reductive hydroformylation carbonylation nickel; NHP ester amino acid alkene propylchloroformate reductive hydroformylation carbonylation.

A nickel-catalyzed, multicomponent regio- and enantioselective coupling via sequential hydroformylation and carbonylation from readily available starting materials has been developed. This modular multicomponent hydrofunctionalization strategy enables the straightforward reductive hydrocarbonylation of a broad range of unactivated alkenes to produce a wide variety of unsym. dialkyl ketones bearing a functionalized α-stereocenter, including enantioenriched chiral α-aryl ketones and α-amino ketones. It uses chiral bisoxazoline as a ligand, silane as a reductant, chloroformate as a safe CO source, and a racemic secondary benzyl chloride or an N-hydroxyphthalimide (NHP) ester of a protected α-amino acid as the alkylation reagent. The benign nature of this process renders this method suitable for late-stage functionalization of complex mols.

Journal of the American Chemical Society published new progress about Alkenes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Recommanded Product: 1-(4-Fluorophenyl)ethyl Alcohol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Mastalir, Matthias; Glatz, Mathias; Pittenauer, Ernst; Allmaier, Guenter; Kirchner, Karl published the artcile< Rhenium-Catalyzed Dehydrogenative Coupling of Alcohols and Amines to Afford Nitrogen-Containing Aromatics and More>, Reference of 403-41-8, the main research area is quinoline pyrimidine quinoxaline pyrrole preparation rhenium catalyzed dehydrogenative coupling; aminomethylated arene preparation rhenium catalyzed acceptorless dehydrogenative coupling.

An efficient synthesis of quinolines, pyrimidines, quinoxalines, pyrroles, and aminomethylated aromatic compounds catalyzed by a well-defined Re(I) PNP pincer complex is described. All reactions proceed with liberation of dihydrogen and elimination of water. Under optimized reaction conditions a wide range of organic functional groups are tolerated. This study demonstrates that rhenium catalysts are performing extremely well in dehydrogenative processes with considerably lower catalyst loadings and shorter reaction times when compared to analogous Mn(I) complexes.

Organic Letters published new progress about Aminomethylation. 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Reference of 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Benessere, Vincenzo; Cucciolito, Maria E.; De Santis, Augusta; Di Serio, Martino; Esposito, Roberto; Melchiorre, Massimo; Nugnes, Fiorella; Paduano, Luigi; Ruffo, Francesco published the artcile< A Sustainable Process for the Production of Varnishes Based on Pelargonic Acid Esters>, Electric Literature of 104-76-7, the main research area is varnish pelargonic acid ester rosin coating.

This work demonstrates the possibility of using pelargonic acid (PA) esters as solvents for vegetable-based varnishes. First, PA was efficiently produced through a chemocatalytic cleavage of oleic acid, practicing an optimized scale-up of previously developed conditions. PA was then esterified with several alcs. ROH (R = Me, i-Pr, n-Bu, n-Hex, 2-ethylhexyl, and sec-octyl) and the products were formulated with a com. rosin (Phenolic Modified Rosin Esters). Dynamic light scattering (DLS) measures and determination of rheol. parameters of the corresponding varnishes disclosed their suitability for applications in offset, coldset, heatset printing inks, and coatings. Furthermore, inks obtained were used to efficiently produce preliminary industrial offset prints.

Journal of the American Oil Chemists’ Society published new progress about Inks. 104-76-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H18O, Electric Literature of 104-76-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Li, Yingze; Krause, Jeanette A.; Guan, Hairong published the artcile< Silane Activation with Cobalt on the POCOP Pincer Ligand Platform>, HPLC of Formula: 52160-51-7, the main research area is aldehyde hydrosilylation cobalt pincer complex catalyst silane siloxane; bisphosphinoxyphenyl cobalt pincer complex preparation crystal structure hydrosilylation catalyst; mol structure phosphinoxyphenyl cobalt pincer complex.

Co POCOP pincer complexes {κP,κC,κP-2,6-(iPr2PO)2C6H3}Co(PMe3)2 (1) and {κP,κC,κP-2,6-(iPr2PO)2-4-NMe2-C6H2}Co(PMe3)2 (2) were synthesized via C-H bond activation of the pincer ligands with HCo(PMe3)4. Silanes such as PhSiH3, Ph2SiH2, and (EtO)3SiH can undergo Si-H oxidative addition with these Co(I) complexes, though reversibly. One of the silane activation products, namely, {κP,κC,κP-2,6-(iPr2PO)2C6H3}Co(H)(SiH2Ph)(PMe3) (3), was isolated and shown to eliminate PhSiH3 upon evaporation to form {κP,κC,κP-2,6-(iPr2PO)2C6H3}Co(PMe3) (4). Under heating, redistribution of PhSiH3 in 3 can take place, resulting in {κP,κC,κP-2,6-(iPr2PO)2C6H3}Co(H)(SiH3)(PMe3) (5) and Ph2SiH2. Complexes 1-3 were established as catalysts for the hydrosilylation of aldehydes bearing various functional groups. According to the mechanistic studies, the silyl hydride species exists in the catalytic cycle, whereas the bis(trimethylphosphine) species sits outside the catalytic cycle. Dissociation of PMe3 is required prior to aldehyde insertion into the silyl hydride species, which is the turnover-limiting step of the catalytic cycle. Consequently, 3 outperforms 1 in catalyzing the hydrosilylation reaction due to the presence of only one PMe3 ligand. The structures of 1-4 were studied by x-ray crystallog.

Organometallics published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 52160-51-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H9NO, HPLC of Formula: 52160-51-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Huang, Xu-Hui; Zheng, Xu; Chen, Zeng-Hui; Zhang, Yu-Ying; Du, Ming; Dong, Xiu-Ping; Qin, Lei; Zhu, Bei-Wei published the artcile< Fresh and grilled eel volatile fingerprinting by e-Nose, GC-O, GC-MS and GC × GC-QTOF combined with purge and trap and solvent-assisted flavor evaporation>, Safety of 2-Ethylhexan-1-ol, the main research area is odor grilled eel volatile fingerprinting; E-Nose; Eel; Extraction methods; Fingerprinting; GC × GC-QTOF; Volatiles.

Fresh and grilled eel were investigated with respect to their volatile compounds and different fingerprinting techniques. An electronic nose (e-Nose) was applied to distinguish the odor between fresh and grilled eels. Purge and trap (P&T) and solvent-assisted flavor evaporation (SAFE) method were used to extract volatile compounds and further analyzed by a gas chromatog. combined with quadrupole mass spectrometry (GC-MS) and a two-dimensional gas chromatog. combined with hybrid quadrupole time-of-flight mass spectrometry (GC × GC-QTOF). SAFE extracted more ketone, alc. and high boiling volatiles in eels than P&T. Considering some distinct compounds extracted by P&T, a P&T and SAFE combined method was chosen. There were 155 volatiles detected in fresh and grilled eels, 93 volatiles were identified. Due to the higher peak capacity, GC × GC-QTOF detected 39 compounds more than GC-MS. The key characteristic volatiles of grilled eel were Me Pr disulfide, di-Me trisulfide, heptane, octane, and camphene. Volatile fingerprinting can be a reference benchmark for identification and quality appraisal of fresh and grilled eel products.

Food Research International published new progress about Alcohols Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 104-76-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H18O, Safety of 2-Ethylhexan-1-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts