Tag: M.W=100-150

Zhang, Guoqi; Zeng, Haisu; Li, Sihan; Johnson, Jahvon; Mo, Zixuan; Neary, Michelle C.; Zheng, Shengping published the artcile< 1-D manganese(II)-terpyridine coordination polymers as precatalysts for hydrofunctionalization of carbonyl compounds>, HPLC of Formula: 403-41-8, the main research area is aldehyde ketone hydrofunctionalization manganese terpyridine coordination polymer catalyst.

Reductive catalysis with earth-abundant metals is currently of increasing importance and shows potential in replacing precious metal catalysis. In this work, catalytic hydroboration and hydrosilylation of ketones and aldehydes achieved by a structurally defined manganese(II) coordination polymer (CP) as a precatalyst under mild conditions is reported. The manganese-catalyzed methodol. can be applied to a range of functionalized aldehydes and ketones with turnover numbers (TON) of up to 990. Preliminary results on the regioselective catalytic hydrofunctionalization of styrenes by the Mn-CP catalyst are also presented.

Dalton Transactions published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, HPLC of Formula: 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kai, Hiroyuki; Morioka, Yasuhide; Tomida, Minoru; Takahashi, Tadashi; Hattori, Maki; Hanasaki, Kohji; Koike, Katsumi; Chiba, Hiroki; Shinohara, Shunji; Kanemasa, Toshiyuki; Iwamoto, Yuka; Takahashi, Kohji; Yamaguchi, Yoshitaka; Baba, Takahiko; Yoshikawa, Takayoshi; Takenaka, Hideyuki published the artcile< 2-Arylimino-5,6-dihydro-4H-1,3-thiazines as a new class of cannabinoid receptor agonists. Part 2: Orally bioavailable compounds>, Recommanded Product: (1-(Aminomethyl)cyclopropyl)methanol, the main research area is cannabinoid receptor analgesia oral bioavailability thiazine derivative SAR.

Structure-activity relationships and efforts to optimize the pharmacokinetic profile of a class of 2-arylimino-5,6-dihydro-4H-1,3-thiazines as cannabinoid receptor agonists are described. Among the compounds examined, compound 14 showed potent affinity and high selectivity for CB2, and compound 23 showed potent affinities against CB1 and CB2. These compounds displayed oral bioavailability.

Bioorganic & Medicinal Chemistry Letters published new progress about Analgesics. 45434-02-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C5H11NO, Recommanded Product: (1-(Aminomethyl)cyclopropyl)methanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Celante, Dian; Diehl, Lisiane O.; Brondani, Leoni N.; Bizzi, Cezar A.; de Castilhos, Fernanda published the artcile< Measurement and Correlation of the Solubility of Terephthalic Acid in Six Pure Solvents and Five Binary Mixtures>, COA of Formula: C8H18O, the main research area is terephthalic acid solubility ethylhexanol DMSO methylpyrrolidinone DMF dimethylacetamide pyridine.

The goal of this work was to measure the solubility of terephthalic acid (TA) in six pure solvents (2-ethyl-1-hexanol (2EH), DMSO, 1-methyl-2-pyrrolidinone, N,N-dimethylformamide, N,N-dimethylacetamide, and pyridine) and five binary mixtures (composed of 2EH and 5 or 10% weight/weight another solvent) from 313.15 to 363.15 K at atm. pressure 101.3 kPa. Experiments were performed by an isothermal method employing an in situ filter to sample only the homogeneous liquid phase, and samples were analyzed by liquid chromatog. Solubility of TA in 2EH is 100-fold lower when compared to the other studied solvents, but a binary mixture composed of 2EH and 5 or 10% weight/weight (solute-free basis) DMSO could increase solubility up to 61 and 165%, resp. Furthermore, the parameters of λh, Apelblat, Wilson, and NRTL models were estimated All of the models fitted the exptl. data with good agreement, but the nonrandom two-liquid (NRTL) model was the most suitable to represent exptl. data.

Journal of Chemical & Engineering Data published new progress about Solubility. 104-76-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H18O, COA of Formula: C8H18O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Yangyang; Du, Zhengyin; Zheng, Tingting; Sun, Hongjian; Li, Xiaoyan published the artcile< Efficient transfer hydrogenation of carbonyl compounds catalyzed by selenophenolato hydrido iron(II) complexes>, COA of Formula: C8H9FO, the main research area is carbonyl compound isopropanol selenophenolato hydrido iron catalyst transfer hydrogenation; alc preparation.

1,3-Cis-Selenophenolato hydrido iron(II) complexes I [R = H, 2-Me, 4-MeO] catalyzed transfer hydrogenation of aldehydes and ketones. Among the three complexes, catalyst I [R = H] exhibited the highest catalytic activity. The catalytic reactions took place under very mild conditions, using isopropanol as solvent and hydrogen source, tBuONa as base under 60-80°. This catalytic system had good tolerance for many functional groups, such as halides, C=C double bonds, nitro groups and cyano groups at the Ph ring of the substrates.

Catalysis Communications published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, COA of Formula: C8H9FO.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Huamin; Shi, Wenyan; Li, Yongli; Yu, Mingming; Gao, Yuan; Lei, Aiwen published the artcile< Photoinduced radical relay way toward α-CF3 ketones with low-cost trifluoromethylation reagents>, Quality Control of 10602-04-7, the main research area is alpha trifluoromethyl ketone preparation; alkyne trifluoromethanesulfonic anhydride trifluoromethylation photoinduction; triethylsilyl trifluoromethanesulfonate alkyne trifluoromethylation photoinduction.

A cost-efficient and practical approach of photoinduction of a radical relay process was disclosed for the synthesis of α-CF3 ketones ArC(O)CH2CF3 [Ar = Ph, 4-ClC6H4, 4-PhC6H4, etc.] using alkynes and low-cost trifluoromethylation reagents. It was showed that trifluoromethylation reagents such as TES-OTf, Tf2O, TMS-OTf, TBS-OTf, H-OTf, and others could be used successfully as inexpensive CF3 precursors under metal-free and redox-neutral conditions. The potential application of this protocol was highlighted and gram-scale synthesis. Mechanistic studies revealed that this transformation might involve a radical process, and acetic acid not only promoted the formation of enol triflates, but also accelerated the in situ conversion from enol triflates to α-CF3 ketones.

CCS Chemistry published new progress about Alkynes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 10602-04-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C9H8O, Quality Control of 10602-04-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Park, Jisung; Nabae, Yuta; Hayakawa, Teruaki; Kakimoto, Masa-aki published the artcile< Highly Selective Two-Electron Oxygen Reduction Catalyzed by Mesoporous Nitrogen-Doped Carbon>, Formula: C6H9NO, the main research area is highly selective two electron oxygen reduction catalyzed; mesoporous nitrogen doped carbon.

Electrochem. reduction of oxygen mols. can produce H2O2, which is an important chem. for a green and sustainable society; therefore, the development of catalysts for this reaction is necessary. We propose mesoporous nitrogen-doped carbon prepared from (1-methyl-1H-pyrrole-2-yl)methanol in the presence of a mesoporous SiO2 template (KIT-6). The nitrogen content of the resulting carbon can be controlled in the range of 0-10 at. % and all prepared samples have well-ordered mesopores with diameters of 3.4-4.0 nm. Electrochem. studies indicate the present materials have high catalytic activities with high selectivity toward H2O2 over 90%. Such high selectivity toward H2O2 is probably due to good mass transport in the catalyst layer, which is enhanced by the mesoporous structure.

ACS Catalysis published new progress about Doping. 52160-51-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H9NO, Formula: C6H9NO.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

You, Peiye; Wei, Rongjia; Ning, Guohong; Li, Dan published the artcile< An Eosin Y Encapsulated Cu(I) Covalent Metal Organic Framework For Efficient Photocatalytic Sonogashira Cross-Coupling Reaction>, HPLC of Formula: 10602-04-7, the main research area is Eosin Y encapsulated copper covalent metal organic framework preparation; internal alkyne selective preparation; iodobenzene alkyne Sonogashira cross coupling copper photocatalyst.

Herein, the encapsulation of an organic dye(i.e., Eosin Y, EY) into a Cu(I) cyclic trinuclear unit(CTU) based covalent-metal organic framework(CMOF), namely EY@JNM-1, as photocatalyst for the Sonogashira cross-coupling reaction of iodobenzene with alkynes to afford internal alkynes I [R = Ph, 4-MeC6H4, 4-ClC6H4, etc.] was reported. The EY@JNM-1 not only exhibited high catalytic activity for the alkynes(>99% conversion) and excellent selectivity for the cross-coupling product(>99%) under mild conditions, but also displayed excellent stability and recyclability.

Chemical Research in Chinese Universities published new progress about Alkynes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 10602-04-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C9H8O, HPLC of Formula: 10602-04-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Donthireddy, S. N. R.; Pandey, Vipin K.; Rit, Arnab published the artcile< [(PPh3)2NiCl2]-Catalyzed C-N Bond Formation Reaction via Borrowing Hydrogen Strategy: Access to Diverse Secondary Amines and Quinolines>, Category: alcohols-buliding-blocks, the main research area is aryl amine methanol nickel catalyst alkylation reaction; arylmethylamine preparation; aminobenzyl alc ethanone nickel catalyst dehydrogenation heterocyclization; quinoline preparation.

Com. available [(PPh3)2NiCl2] was found to be an efficient catalyst for the mono-N-alkylation of (hetero)aromatic amines, employing alcs. to deliver diverse secondary amines, including the drug intermediates chloropyramine and mepyramine in excellent yields (up to 97%) via the borrowing hydrogen strategy. This method shows a superior activity (TON up to 10000) with a broad substrate scope at a low catalyst loading of 1 mol % and a short reaction time. Further, this strategy was also successful in accessing various quinoline derivatives following the acceptorless dehydrogenation pathway.

Journal of Organic Chemistry published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Mendoza-Pedroza, Jose de Jesus; Sanchez-Ramirez, Eduardo; Segovia-Hernandez, Juan Gabriel; Hernandez, Salvador; Orjuela, Alvaro published the artcile< Recovery of alcohol industry wastes: Revaluation of fusel oil through intensified processes>, Name: 2-Ethylhexan-1-ol, the main research area is alc industry waste fusel oil recovery.

Fusel oil is a mixture obtained as a side cut during ethanol distillation, mainly composed of i-amyl alc., water, ethanol, isobutanol, and other alcs. Currently, fusel separation into the constitutive alcs. is accomplished by batch or continuous distillation involving different columns in an energy-intensive process. Moreover, fusel oil presents a particular thermodn. behavior projected in several azeotropes, making the purification of fusel oil a challenging process. In this work is proposed a novel distillation scheme to purify isoamyl alc. from other fusel alcs. by using a dividing wall column scheme. In order to determine the benefits of using such intensified technol., a comparison with the conventional scheme was carried out. In order to accurately represent the thermodn. equilibrium, data for phase equilibrium was needed to the correctly design of the purification process. Both, the traditional distillation scheme and the dividing wall column were modeled using Aspen Plus and optimized by using a hybrid stochastic algorithm. Results indicate that the dividing wall column is not only more efficient in term of energy intensity (2785 kJ/kg Amyl alc.) against (3497 kJ/Kg Amyl alc.) the conventional scheme, but also it offers large economic savings compared with the conventional scheme (27% savings).

Chemical Engineering and Processing published new progress about Alcohols Role: IMF (Industrial Manufacture), PREP (Preparation). 104-76-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H18O, Name: 2-Ethylhexan-1-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kaur, Mandeep; U Din Reshi, Noor; Patra, Kamaless; Bhattacherya, Arindom; Kunnikuruvan, Sooraj; Bera, Jitendra K. published the artcile< A Proton-Responsive Pyridyl(benzamide)-Functionalized NHC Ligand on Ir Complex for Alkylation of Ketones and Secondary Alcohols>, Electric Literature of 5344-90-1, the main research area is pyridylbenzamidecarbene iridium complex preparation catalyst alkylation ketone alc; crystal structure pyridylbenzamidecarbene iridium complex; mol structure pyridylbenzamidecarbene iridium complex; Borrowing-Hydrogen; Homogeneous Catalysis; Hydrogen transfer; Metal-Ligand Cooperation; Proton-Responsive Ligand; Reaction Mechanism.

A Cp*Ir(III) complex (1) of a newly designed ligand L1 featuring a proton-responsive pyridyl(benzamide) appended on N-heterocyclic carbene (NHC) was synthesized. The mol. structure of 1 reveals a dearomatized form of the ligand. The protonation of 1 with HBF4 in THF gives the corresponding aromatized complex [Cp*Ir(L1H)Cl]BF4 (2). Both compounds were characterized spectroscopically and by x-ray crystallog. The protonation of 1 with acid was examined by 1H NMR and UV-visible spectra. The proton-responsive character of 1 is exploited for catalyzing α-alkylation of ketones and β-alkylation of secondary alcs. using primary alcs. as alkylating agents through H-borrowing methodol. Compound 1 is an effective catalyst for these reactions and exhibits a superior activity in comparison to a structurally similar Ir complex [Cp*Ir(L2)Cl]PF6 (3) lacking a proton-responsive pendant amide moiety. The catalytic alkylation was characterized by a wide substrate scope, low catalyst and base loadings, and a short reaction time. The catalytic efficacy of 1 is also demonstrated for the syntheses of quinoline and lactone derivatives via acceptorless dehydrogenation, and selective alkylation of two steroids, pregnenolone and testosterone. Detailed mechanistic studies and DFT calculations substantiate the role of the proton-responsive ligand in the H-borrowing process.

Chemistry – A European Journal published new progress about Alkylating agents (pyridyl(benzamide) Ir complexes). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Electric Literature of 5344-90-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts