Tag: M.W=100-150

Bird, Matthew J. published the artcileMeasuring rates of ATP synthesis, Name: (S)-2-hydroxysuccinic acid, the main research area is digitonin ATP mitochondria measuring rate; ATP synthesis; Bioenergetics; Mitochondria; Oxidative phosphorylation; Oxidative phosphorylation (OXPHOS); β-oxidation.

Here, we offer you a high-throughput assay to measure the ATP synthesis capacity in cells or isolated mitochondria. More specifically, the assay is linked to the mitochondrial’ electron transport chain components of your interest being either through complex I (with or without a linkage to pyruvate dehydrogenase activity), through complex II, or through the electron transport flavoprotein and complex I (beta-oxidation of fatty acids).

Methods in Molecular Biology (New York, NY, United States) published new progress about Cell membrane. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Name: (S)-2-hydroxysuccinic acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Pan, Mingzhang published the artcileReduction in PM and NOX of a diesel engine integrated with n-octanol fuel addition and exhaust gas recirculation, Category: alcohols-buliding-blocks, the main research area is nitrogen oxide octanol diesel engine exhaust gas particulate matter.

N-Octanol with its high energy d. and high cetane number has similar fuel properties as diesel fuel, and is thus considered an excellent choice for alc. fuels as a substitute for diesel. This study focused on the effects of exhaust gas recirculation (EGR) combined with the addition of n-octanol on the performance, emissions, and particulate matter (PM) of a direct injection diesel engine. The results show that the curves of the in-cylinder pressure of n-octanol/diesel blends nearly overlap those of pure diesel fuel under the test conditions. At a low EGR ratio, the brake thermal efficiency of n-octanol/diesel blends is higher than that of diesel fuel. With an increase in the EGR ratio, the results show that nitrogen oxide (NOX) emissions decrease, whereas carbon monoxide (CO) and soot emissions significantly increase. However, the use of n-octanol/diesel blends can inhibit the increase in CO and soot emissions appreciably. In addition, with an increase in n-octanol content in the blends, the number concentration of particles on the particle size distribution decreases gradually. To summarize, a simultaneous reduction in NOX and PM emissions under a combined operation of small EGR ratios and n-octanol blends can be realized, thereby improving the brake thermal efficiency.

Energy (Oxford, United Kingdom) published new progress about Cetane number. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Tong published the artcileHigh-Speed Countercurrent Chromatography-Based Method for Simultaneous Recovery and Separation of Natural Products from Deep Eutectic Solvent Extracts, Safety of (S)-2-hydroxysuccinic acid, the main research area is natural product separation extraction deep eutectic solvent.

The use of deep eutectic solvents (DESs) to extract natural products has attracted considerable attention in recent years. However, the recovery of extracted compounds and DES from DES extracts is still a barrier, which restricts the large-scale application of DESs. Here, we proposed a high-speed countercurrent chromatog. (HSCCC)-based method to recover extracted compounds and DES. As a proof of concept, the chrysanthemum DES extract was selected to verify the method. We first prepared a series of DES-based solvent systems and screened them based on their phys. and chem. properties. Only the system composed of choline chloride/L-malic acid, water, and Et acetate (1:1:1, volume/volume/v) was suitable. By using the solvent system for HSCCC separation, the target compounds and DES in the chrysanthemum DES extract were both successfully recovered with high recovery yields over 95%. Then, we investigated the reusability of the recovered DES and found that it could be repeatedly reused for three times without any performance deterioration. All these results indicated that the proposed method is feasible and efficient, which has great potential for application. Moreover, the method may also be used in other fields where the separation process is needed, such as organic synthesis, chem. separation, biosepn., and biotransformation. A simple and efficient method was developed for recycling deep eutectic solvents used in the natural product green extraction and separation process.

ACS Sustainable Chemistry & Engineering published new progress about Chrysanthemum. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Safety of (S)-2-hydroxysuccinic acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Li, Yanqing published the artcileBis(N-acylated imidazolin-2-imine) nickel catalyzed norbornene copolymerization with methyl acrylate, Product Details of C4H11NO2, the main research area is imidazolin imine catalyzed norbornene methyl acrylate copolymerization.

The incorporation of even a small number of polar functional groups in the polyolefin backbone is sufficient to improve the polyolefin properties. Compared with palladium catalyzed direct copolymerization of olefins with polar vinyl monomers, the development of low-cost nickel-based catalysts is more challenging because of their higher oxophilicity. On the basis of the advantage of reducing the electrophilicity of the nickel center by the installation of strongly electron-donating ligands, we herein report the synthesis of novel bis(N-acylated imidazolin-2-imine) nickel complexes for norbornene polymerization and copolymerization with polar monomers. Moreover, the Ph substituent on the imidazoline ligand is expected to enhance the tolerance of the nickel catalyst toward polar functional groups, thus allowing the copolymerization of norbornene with com. Me acrylate to afford high mol. weight functionalized cyclic olefin copolymers (COCs) with moderate activity and reasonable comonomer content.

Polymer Chemistry published new progress about Contact angle. 22483-09-6 belongs to class alcohols-buliding-blocks, name is 2,2-Dimethoxyethanamine, and the molecular formula is C4H11NO2, Product Details of C4H11NO2.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Albu, Paul Constantin published the artcilepH and Design on n-Alkyl Alcohol Bulk Liquid Membranes for Improving Phenol Derivative Transport and Separation, Safety of n-Octanol, the main research area is alkyl alc bulk liquid membrane transport separation; bulk liquid membranes; liquid membrane design; n–decanol membranes; n–octanol membranes; pH operational parameter; permeation module design; phenol derivative separation; phenol derivative transports.

Regardless of the type of liquid membrane (LM) (Bulk Liquid Membranes (BLM), Supported Liquid Membranes (SLM) or Emulsion Liquid Membranes (ELM)), transport and separation of chem. species are conditioned by the operational (OP) and constructive design parameters (DP) of the permeation module. In the present study, the pH of the aqueous source phase (SP) and receiving phase (RP) of the proposed membrane system were selected as operational parameters. The mode of contacting the phases was chosen as the convective transport generator. The experiments used BLM-type membranes with spheres in free rotation as film contact elements of the aqueous phases with the membrane. The target chem. species were selected in the range of phenol derivatives (PD), 4-nitrophenol (NP), 2,4-dichlorophenol (DCP) and 2,4-dinitrophenol (DNP), all being substances of tech.-economic and environmental interest. Due to their acid character, they allow the evaluation of the influence of pH as a determining operational parameter of transport and separation through a membrane consisting of n-octanol or n-decanol (n-AlcM). The comparative study performed for the transport of 4-nitrophenol (NP) showed that the module based on spheres (Ms) was more performant than the one with phase dispersion under the form of droplets (Md). The sphere material influenced the transport of 4-nitrophenol (NP). The transport module with glass spheres (Gl) was superior to the one using copper spheres (Cu), but especially with the one with steel spheres (St). In all the studied cases, the sphere-based module (Ms) had superior transport results compared to the module with droplets (Md). The extraction efficiency (EE) and the transport of 2,4-dichlorophenol (DCP) and 2,4-dinitrophenol (DNP), studied in the module with glass spheres, showed that the two phenolic derivatives could be separated by adjusting the pH of the source phase. At the acidic pH of the source phase (pH = 2), the two derivatives were extracted with good results (EE > 90%), while for pH values ranging from 4 to 6, they could be separated, with DCP having doubled separation efficiency compared to DNP. At a pH of 8 in the source phase, the extraction efficiency halved for both phenolic compounds

Membranes (Basel, Switzerland) published new progress about Contact angle. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Safety of n-Octanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kou, Jinfang published the artcilePrecisely controlled Pd nanoclusters confined in porous organic cages for size-dependent catalytic hydrogenation, Formula: C8H14O, the main research area is palladium nanocluster preparation catalytic hydrogenation property.

The precise size-controlled formation of palladium (Pd) nanoclusters with size-dependent catalytic activity was achieved through a cage confinement strategy. In this process, three typical porous organic cages (POCs) with gradually decreasing cavity diameters were used as encapsulation carriers. A series of Pd nanoclusters-based catalysts with corresponding Pd cluster sizes of 0.73, 0.68, and 0.43 nm, resp., was effectively fabricated by confining the Pd nanoclusters in size-adjustable cavities. The obtained Pd@POCs nanocatalysts exhibited excellent crystallinity, high stability, fascinating morphol. characteristics, and superior catalytic hydrogenation performance. Especially, the size-dependent catalytic performance toward hydrogenation of 4-nitrophenol and semi-hydrogenation of alkyne compounds was demonstrated by exptl. results and theor. calculations The prepared Pd(1.71%)@FT-RCC3 catalyst with the smallest Pd cluster size of about 0.43 nm showed the best catalytic performance. This study promotes a better understanding of size-dependent catalysis and provides a new strategy for the fabrication of customized nanocatalysts.

Applied Catalysis, B: Environmental published new progress about Crystallinity. 107-54-0 belongs to class alcohols-buliding-blocks, name is 3,5-Dimethylhex-1-yn-3-ol, and the molecular formula is C8H14O, Formula: C8H14O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Viola, Arnaud published the artcileOn the importance of the crystalline surface structure on the catalytic activity and stability of tailored unsupported cobalt nanoparticles for the solvent-free acceptor-less alcohol dehydrogenation, Application of n-Octanol, the main research area is surface structure dehydrogenation catalysts cobalt nanoparticle; Acceptorless dehydrogenation of alcohols; Cobalt; Molecular hydrogen; Nanoparticles; PM-IRRAS.

Unsupported nanoparticles are now recognized as model catalysts to evaluate the intrinsic activity of metal particles, irresp. of that of the support. Co nanoparticles with different morphologies, rods, diabolos and cubes have been prepared by the polyol process and tested for the acceptorless catalytic dehydrogenation of alcs. under solvent-free conditions. Rods crystallize with the pure hcp. structure, diabolos with a mixture of hcp. and fcc. phases, while the cubes crystallize in a complex mixture of hcp., fcc. and ε-Co phases. All the cobalt particles are found to be highly selective towards the oxidation of a model secondary alc., octan-2-ol, into the corresponding ketone while no significant activity is found with octan-1-ol. Our results show the strong influence of particle shape on the activity and catalytic stability of the catalysts: Co nanorods display the highest conversion (85%), selectivity (95%) and recyclability compared to Co diabolos and Co cubes. We correlate the nanorods excellent stability with a strong binding of carboxylate ligands on their {1 1 2̅ 0} facets, preserving their crystalline superficial structure, as evidenced by phase modulation IR reflection absorption spectroscopy.

Journal of Colloid and Interface Science published new progress about Crystallinity. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Application of n-Octanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Garcia, Margarita published the artcileSequential Non-Saccharomyces and Saccharomyces cerevisiae fermentations to reduce the alcoholcontent in wine, Related Products of alcohols-buliding-blocks, the main research area is Saccharomyces Wickerhamomyces Meyerozyma Metschnikowia fermentation alc reduction wine.

Over the last decades, the average alc. content of wine has increased due to climate change and consumer preferences for particular wine styles that resulted in increased grape sugar levels at harvest. Therefore, alc. reduction is a current challenge in the winemaking industry. Among several strategies under study, the use of non-conventional yeasts in combination with Saccharomyces cerevisiae plays an important role for lowering ethanol production in wines nowadays. In the present work, 33 native non-Saccharomyces strains were assayed in sequential culture with a S. cerevisiae wine strain to determine their potential for reducing the alc. content in Malvar white wines. Four of the non-Saccharomyces strains (Wickerhamomyces anomalus 21A-5C, Meyerozyma guilliermondii CLI 1217, and two Metschnikowia pulcherrima (CLI 68 and CLI 460)) studied in sequential combination with S. cerevisiae CLI 889 were best able to produce dry wines with decreased alc. proportion in comparison with one that was inoculated only with S. cerevisiae. These sequential fermentations produced wines with between 0.8% (volume/volume) and 1.3% (volume/volume) lower ethanol concentrations in Malvar wines, showing significant differences compared with the control. In addition, these combinations provided favorable oenol. characteristics to wines such as high glycerol proportion, volatile higher alcs., and esters with fruity and sweet character.

Fermentation published new progress about Candida stellata. 505-10-2 belongs to class alcohols-buliding-blocks, name is 3-(Methylthio)propan-1-ol, and the molecular formula is C4H10OS, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Deed, Rebecca C. published the artcileThe role of yeast ARO8, ARO9 and ARO10 genes in the biosynthesis of 3-(methylthio)-1-propanol from L-methionine during fermentation in synthetic grape medium, Product Details of C4H10OS, the main research area is Saccharomyces fermentation synthetic grape medium methionol L methionine.

3-(Methylthio)-1-propanol (methionol), produced by yeast as an end-product of L-methionine (L-Met) catabolism, imparts off-odours reminiscent of cauliflower and potato to wine. Saccharomyces cerevisiae ARO genes, including transaminases Aro8p and Aro9p, and decarboxylase Aro10p, catalyze two key steps forming methionol via the Ehrlich pathway. We compared methionol concentrations in wines fermented by single Δaro8, Δaro9 and Δaro10 deletants in lab strain BY4743 vs. wine strain Zymaflore F15, and F15 double- and triple-aro deletants vs. single-aro deletants, using headspace-solid phase microextraction coupled with gas chromatog.-mass spectrometry. Deletion of two or more aro genes increased growth lag phase, with the greatest delay exhibited by F15 Δaro8 Δaro9. The single Δaro8 deletion decreased methionol by 44% in BY4743 and 92% in F15, while the Δaro9 deletion increased methionol by 46% in F15 but not BY4743. Single deletion of Δaro10 had no effect on methionol. Unexpectedly, F15 Δaro8 Δaro9 and F15 Δaro8 Δaro9 Δaro10 produced more methionol than F15 Δaro8. In the absence of Aro8p and Aro9p, other transaminases may compensate or an alternative pathway may convert methanethiol to methionol. Our results confirm that Ehrlich pathway genes differ greatly between lab and wine yeast strains, impacting downstream products such as methionol.

FEMS Yeast Research published new progress about Cell enlargement. 505-10-2 belongs to class alcohols-buliding-blocks, name is 3-(Methylthio)propan-1-ol, and the molecular formula is C4H10OS, Product Details of C4H10OS.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Feng, Li published the artcileA novel strategy based on targeted cellular metabolomics for quantitatively evaluating anti-aging effect and screening effective extracts of Erzhi Wan, Category: alcohols-buliding-blocks, the main research area is Erzhi wan antiaging targeted cellular metabolomics quant efficacy evaluation; Analytic hierarchy process; Quantitative effect evaluation; Receiver operating characteristic curve; Targeted cellular metabolomics; Traditional Chinese medicine.

The complexity of ingredients in traditional Chinese medicine (TCM) makes it challenging to clarify its efficacy in an acceptable and scientific approach. The present study was aimed to use quantification results from targeted cellular metabolomics to evaluate anti-aging efficacy of a famous Chinese medicine formula, Erzhi Wan (EZW), and screen possible effective extracts, depending on the developed strategy integrating multivariate receiver operating characteristic (ROC) curve and analytic hierarchy process (AHP). In this study, senescent NRK cells induced by D-galactose were treated with drug-containing serum of EZW and four kinds of extracts (petroleum ether, Et acetate, butanol and water). Intermediates of two major metabolic pathways for energy synthesis, tricarboxylic acid (TCA) cycle and glycolysis, were accurately quantified by GC-MS/MS to identify discriminate metabolites for clarifying therapeutic mechanism of EZW based on multivariate statistical anal. Senescent and non-senescent cells were successfully distinguished using these metabolites by ROC curve anal. Next, these metabolites were used as evaluation indexes to quant. reflect different effect of EZW and its extracts, according to the role of them in distinguishing groups and in conjunction with AHP. In vitro detection of senescence-associated β-galactosidase (SA-β-gal) activity was used to verify the reliability of evaluation results. The reversal after treatment of drug-containing serum of EZW and extracts was observed, and the petroleum ether extract might be the potential active extract responsible for the major anti-aging effect of EZW, which was in agreement with in vitro experiments Altogether, metabolomics was a powerful approach for evaluation efficacy and elucidation action mechanisms of TCM. The integrated evaluation strategy in this paper with properties of high practicality, feasibility and effectivity was expected to provide a new insight into comprehensive and quant. efficacy evaluation.

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences published new progress about Chinese medicine. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts