Tag: 500-600

Xie, Youwei et al. published their research in Journal of the American Chemical Society in 2016 | CAS: 863659-89-6

(S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol (cas: 863659-89-6) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Recommanded Product: (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol

Catalytic Asymmetric Vinylogous Prins Cyclization: A Highly Diastereo- and Enantioselective Entry to Tetrahydrofurans was written by Xie, Youwei;Cheng, Gui-Juan;Lee, Sunggi;Kaib, Philip S. J.;Thiel, Walter;List, Benjamin. And the article was included in Journal of the American Chemical Society in 2016.Recommanded Product: (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol This article mentions the following:

We describe the design and development of the first catalytic asym. vinylogous Prins cyclization. This reaction constitutes an efficient approach for highly diastereo- and enantioselective synthesis of tetrahydrofurans (THFs) and is catalyzed by a confined chiral imidodiphosphoric acid (IDP). Aromatic and heteroaromatic aldehydes react with various 3,5-dien-1-ols to afford 2,3-disubstituted THFs in excellent selectivity (d.r. > 20:1, e.r. up to 99:1). Aliphatic aldehydes react with similarly excellent results when a highly acidic imidodiphosphorimidate (IDPi) catalyst is used. With a racemic dienyl alc., the reaction proceeds via a kinetic resolution DFT calculations suggest an explanation for unusually high stereoselectivity. In the experiment, the researchers used many compounds, for example, (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol (cas: 863659-89-6Recommanded Product: (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol).

(S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol (cas: 863659-89-6) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Recommanded Product: (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Xie, Youwei et al. published their research in Journal of the American Chemical Society in 2016 | CAS: 863659-89-6

(S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol (cas: 863659-89-6) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Recommanded Product: (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol

Catalytic Asymmetric Vinylogous Prins Cyclization: A Highly Diastereo- and Enantioselective Entry to Tetrahydrofurans was written by Xie, Youwei;Cheng, Gui-Juan;Lee, Sunggi;Kaib, Philip S. J.;Thiel, Walter;List, Benjamin. And the article was included in Journal of the American Chemical Society in 2016.Recommanded Product: (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol This article mentions the following:

We describe the design and development of the first catalytic asym. vinylogous Prins cyclization. This reaction constitutes an efficient approach for highly diastereo- and enantioselective synthesis of tetrahydrofurans (THFs) and is catalyzed by a confined chiral imidodiphosphoric acid (IDP). Aromatic and heteroaromatic aldehydes react with various 3,5-dien-1-ols to afford 2,3-disubstituted THFs in excellent selectivity (d.r. > 20:1, e.r. up to 99:1). Aliphatic aldehydes react with similarly excellent results when a highly acidic imidodiphosphorimidate (IDPi) catalyst is used. With a racemic dienyl alc., the reaction proceeds via a kinetic resolution DFT calculations suggest an explanation for unusually high stereoselectivity. In the experiment, the researchers used many compounds, for example, (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol (cas: 863659-89-6Recommanded Product: (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol).

(S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol (cas: 863659-89-6) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Recommanded Product: (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hyun, Myung Ho et al. published their research in Bulletin of the Korean Chemical Society in 2006 | CAS: 863659-89-6

(S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol (cas: 863659-89-6) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Quality Control of (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol

Preparation of a new chiral stationary phase based on (2S,3S)-O,O’-bis-(10-undecenoyl)-N,N’-bis-(3,5-dinitrobenzoyl)-2,3-diamino-1,4-butanediol and its application for the liquid chromatographic resolution of enantiomers was written by Hyun, Myung Ho;Boo, Chang Jin;Choi, Hee Jung;Kim, Yun Kyoung;Kang, Bu Sung;Ha, Hyun Ju;Choi, Min Ki;Tan, Guanghui. And the article was included in Bulletin of the Korean Chemical Society in 2006.Quality Control of (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol This article mentions the following:

A new liquid chromatog. chiral stationary phase based on (2S,3S)-O,O’-bis-(10-undecenoyl)-N,N’-bis-(3,5-dinitrobenzoyl)-2,3-diamino-1,4-butanediol was prepared starting from (2R,3R)-1,4-bis(benzyloxy)-2,3-butanediol. The new chiral stationary phase was applied to the resolution of racemic anilide derivatives of N-acetyl-伪-amino acids, 1,1′-bi-2-naphthol and 3,3′-diaryl-1,1′-bi-2-naphthols. It was also applied to the resolution of some chiral drugs including bendroflumethiazide, naproxen and alminoprofen. In every case, the chiral recognition efficiency of the new CSP was quite excellent. In the experiment, the researchers used many compounds, for example, (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol (cas: 863659-89-6Quality Control of (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol).

(S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol (cas: 863659-89-6) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Quality Control of (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Berkessel, Albrecht et al. published their research in Organometallics in 2011 | CAS: 863659-89-6

(S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol (cas: 863659-89-6) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Application In Synthesis of (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol

Light-induced enantioselective hydrogenation using chiral derivatives of Casey’s iron-cyclopentadienone catalyst was written by Berkessel, Albrecht;Reichau, Sebastian;von der Hoeh, Adrian;Leconte, Nicolas;Neudorfl, Joerg-M.. And the article was included in Organometallics in 2011.Application In Synthesis of (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol This article mentions the following:

Iron cyclopentadienone half-sandwich complexes I [8a–e; R = H, Me, Ph, 2-naphthyl, 3,5-(CF3)2C6H3] and an (R)-enantiomer of 8a, ent-8a, containing chiral (S)- and (R)-MonoPhos ligands, chirally modified Casey’s catalysts, were prepared by Me3NO- or photolysis-induced substitution of the parent tricarbonyl complex, [[畏4-O(CH2)2(C:CSiMe3)2C:O]Fe(CO)3] (7) with the chiral phosphoramidite ligands. Crystal structures of 8a and 8c were determined The complexes 8a–e and ent-8a catalyze asym. hydrogenation of acetophenone into (S)- and (R)-1-phenylethanol, resp., with 90% yields and up to 32% ee, the reaction being induced by UV irradiation Photolysis was also used to convert the dicarbonyl phosphoramidite complexes 8 to the coordinatively unsaturated monocarbonyl complexes, which are intermediates in the catalytic cycle of ketone hydrogenation. Hydrogen uptake by the latter species affords the “loaded” diastereomeric hydrides [[畏5-O(CH2)2(C:CSiMe3)2COH]Fe(CO)(L*)] [10, 11; L* = unsubstituted (S)-MonoPhos] and an achiral hydride [[畏5-O(CH2)2(C:CSiMe3)2COH]Fe(CO)2] (6), as evidenced by 1H NMR spectroscopy. Thus, the preparation of sensitive iron hydrides by the typically low-yielding Hieber reaction could be avoided. Instead, the catalytic cycle is accessed from air-stable carbonyl precursors. In the hydridic form of the phosphoramidite-carbonyl catalysts, the iron atom itself becomes a stereocenter. NMR spectroscopy confirmed the generation of two hydride diastereomers. With the MonoPhos iron dicarbonyl complex, moderate enantioselectivity (up to 31% ee) was achieved in the hydrogenation of acetophenone. In the experiment, the researchers used many compounds, for example, (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol (cas: 863659-89-6Application In Synthesis of (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol).

(S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol (cas: 863659-89-6) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Application In Synthesis of (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hyun, Myung Ho et al. published their research in Bulletin of the Korean Chemical Society in 2006 | CAS: 863659-89-6

(S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol (cas: 863659-89-6) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Quality Control of (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol

Preparation of a new chiral stationary phase based on (2S,3S)-O,O’-bis-(10-undecenoyl)-N,N’-bis-(3,5-dinitrobenzoyl)-2,3-diamino-1,4-butanediol and its application for the liquid chromatographic resolution of enantiomers was written by Hyun, Myung Ho;Boo, Chang Jin;Choi, Hee Jung;Kim, Yun Kyoung;Kang, Bu Sung;Ha, Hyun Ju;Choi, Min Ki;Tan, Guanghui. And the article was included in Bulletin of the Korean Chemical Society in 2006.Quality Control of (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol This article mentions the following:

A new liquid chromatog. chiral stationary phase based on (2S,3S)-O,O’-bis-(10-undecenoyl)-N,N’-bis-(3,5-dinitrobenzoyl)-2,3-diamino-1,4-butanediol was prepared starting from (2R,3R)-1,4-bis(benzyloxy)-2,3-butanediol. The new chiral stationary phase was applied to the resolution of racemic anilide derivatives of N-acetyl-α-amino acids, 1,1′-bi-2-naphthol and 3,3′-diaryl-1,1′-bi-2-naphthols. It was also applied to the resolution of some chiral drugs including bendroflumethiazide, naproxen and alminoprofen. In every case, the chiral recognition efficiency of the new CSP was quite excellent. In the experiment, the researchers used many compounds, for example, (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol (cas: 863659-89-6Quality Control of (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol).

(S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol (cas: 863659-89-6) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Quality Control of (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Berkessel, Albrecht et al. published their research in Organometallics in 2011 | CAS: 863659-89-6

(S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol (cas: 863659-89-6) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Application In Synthesis of (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol

Light-induced enantioselective hydrogenation using chiral derivatives of Casey’s iron-cyclopentadienone catalyst was written by Berkessel, Albrecht;Reichau, Sebastian;von der Hoeh, Adrian;Leconte, Nicolas;Neudorfl, Joerg-M.. And the article was included in Organometallics in 2011.Application In Synthesis of (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol This article mentions the following:

Iron cyclopentadienone half-sandwich complexes I [8a–e; R = H, Me, Ph, 2-naphthyl, 3,5-(CF3)2C6H3] and an (R)-enantiomer of 8a, ent-8a, containing chiral (S)- and (R)-MonoPhos ligands, chirally modified Casey’s catalysts, were prepared by Me3NO- or photolysis-induced substitution of the parent tricarbonyl complex, [[η4-O(CH2)2(C:CSiMe3)2C:O]Fe(CO)3] (7) with the chiral phosphoramidite ligands. Crystal structures of 8a and 8c were determined The complexes 8a–e and ent-8a catalyze asym. hydrogenation of acetophenone into (S)- and (R)-1-phenylethanol, resp., with 90% yields and up to 32% ee, the reaction being induced by UV irradiation Photolysis was also used to convert the dicarbonyl phosphoramidite complexes 8 to the coordinatively unsaturated monocarbonyl complexes, which are intermediates in the catalytic cycle of ketone hydrogenation. Hydrogen uptake by the latter species affords the “loaded” diastereomeric hydrides [[η5-O(CH2)2(C:CSiMe3)2COH]Fe(CO)(L*)] [10, 11; L* = unsubstituted (S)-MonoPhos] and an achiral hydride [[η5-O(CH2)2(C:CSiMe3)2COH]Fe(CO)2] (6), as evidenced by 1H NMR spectroscopy. Thus, the preparation of sensitive iron hydrides by the typically low-yielding Hieber reaction could be avoided. Instead, the catalytic cycle is accessed from air-stable carbonyl precursors. In the hydridic form of the phosphoramidite-carbonyl catalysts, the iron atom itself becomes a stereocenter. NMR spectroscopy confirmed the generation of two hydride diastereomers. With the MonoPhos iron dicarbonyl complex, moderate enantioselectivity (up to 31% ee) was achieved in the hydrogenation of acetophenone. In the experiment, the researchers used many compounds, for example, (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol (cas: 863659-89-6Application In Synthesis of (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol).

(S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol (cas: 863659-89-6) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Application In Synthesis of (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hyun, Myung Ho et al. published their research in Journal of Liquid Chromatography & Related Technologies in 2005 | CAS: 863659-89-6

(S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol (cas: 863659-89-6) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Application In Synthesis of (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol

Liquid chromatographic resolution of 1,1′-bi-2-naphthol and 3,3′-diaryl-1,1′-bi-2-naphthols on Pirkle-type chiral stationary phases based on leucine and phenylglycine was written by Hyun, Myung Ho;Kim, Kwang Soo;Cho, Yoon Jae. And the article was included in Journal of Liquid Chromatography & Related Technologies in 2005.Application In Synthesis of (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol This article mentions the following:

Pirkle-type chiral stationary phases (CSPs) based on (S)-leucine and (S)-phenylglycine were applied in the resolution of 1,1′-bi-2-naphthol and 3,3′-diaryl-1,1′-bi-2-naphthols. Among the two Pirkle-type CSPs, the one based on (S)-N-(3,5-dinitrobenzoyl)leucine N-propylamide is excellent and most widely applicable. The elution orders for the resolution of 1,1′-bi-2-naphthol on the CSPs based on (S)-N-(3,5-dinitrobenzoyl)leucine N-propylamide and (S)-N-(3,5-dinitrobenzoyl)phenylglycine N-propylamide were opposite to those for the resolution of 3,3′-diaryl-1,1′-bi-2-naphthols. To rationalize the reversed elution orders, the authors proposed two different chiral recognition mechanisms based on the chromatog. resolution behaviors, with the aid of the CPK mol. model study. In the experiment, the researchers used many compounds, for example, (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol (cas: 863659-89-6Application In Synthesis of (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol).

(S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol (cas: 863659-89-6) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Application In Synthesis of (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Feng et al. published their research in Organic & Biomolecular Chemistry in 2009 | CAS: 863659-89-6

(S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol (cas: 863659-89-6) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Safety of (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol

Synthesis and application of bulky phosphoramidites: highly effective monophosphorus ligands for asymmetric hydrosilylation of styrenes was written by Zhang, Feng;Fan, Qing-Hua. And the article was included in Organic & Biomolecular Chemistry in 2009.Safety of (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol This article mentions the following:

A series of bulky monodentate phosphoramidite ligands were synthesized from chiral 3,3′-diaryl substituted BINOL derivatives and achiral or dendritic amines in good yields. Asym. hydrosilylation of styrenes with trichlorosilane in the presence of palladium complexes of these bulky ligands gave chiral silanes in high yields with excellent activity and productivity. Oxidation of these chiral silanes with hydrogen peroxide gave the corresponding chiral secondary alcs. in up to 96% ee. In the experiment, the researchers used many compounds, for example, (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol (cas: 863659-89-6Safety of (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol).

(S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol (cas: 863659-89-6) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Safety of (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Lian et al. published their research in Angewandte Chemie, International Edition in 2011 | CAS: 863659-89-6

(S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol (cas: 863659-89-6) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.HPLC of Formula: 863659-89-6

The long-arm effect: influence of axially chiral phosphoramidite ligands on the diastereo- and enantioselectivity of the tandem 1,4-addition/fluorination was written by Wang, Lian;Meng, Wei;Zhu, Chuan-Le;Zheng, Yan;Nie, Jing;Ma, Jun-An. And the article was included in Angewandte Chemie, International Edition in 2011.HPLC of Formula: 863659-89-6 This article mentions the following:

Alkylidene-substituted β-aryl β-ketoesters undergo asym. tandem Michael addition and electrophilic fluorination in reaction with dialkylzinc compounds and N-fluorobenzenesulfonimide, catalyzed by copper(II) triflate, modified with axial chiral 1,1′-binaphthalene 2,2′-phosphoramidite monodentate ligands QO2PNR32 (1a–r, Q = 3,3′-diaryl-1,1′-binaphthalene-2,2-diyl, R3 = Me, Et, iPr, Bu), yielding α-fluoro-β-ketoesters I (3a–v, R = H, 4-MeO, 3-Me, 2-Me, 4-Cl, 4-Br; R1 = Et, Me, n-Pr, Bu; R2 = Ph, 2-MeOC6H4, 3-MeOC6H4, 4-MeOC6H4, 4-CF3C6H4, 2-naphthyl, 2-furyl, 2-thienyl)with high yields and >85% ee. The variety of 3,3′-disubstituted chiral phosphoramidites were evaluated, the 4-biphenylyl and 4-(2-naphthyl)phenyl substituents provided optimal chiral induction, 75-90%. N-Substituents of the phosphoramidites 1 play a minor role in induction, the diethylamino group as NR32 being optimal. In the experiment, the researchers used many compounds, for example, (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol (cas: 863659-89-6HPLC of Formula: 863659-89-6).

(S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol (cas: 863659-89-6) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.HPLC of Formula: 863659-89-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kano, Taichi et al. published their research in Tetrahedron Letters in 2006 | CAS: 863659-89-6

(S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol (cas: 863659-89-6) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Safety of (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol

Design of chiral tin(IV) aryloxide as a mild Lewis acid catalyst for enantioselective Diels-Alder reaction was written by Kano, Taichi;Konishi, Teppei;Konishi, Shunsuke;Maruoka, Keiji. And the article was included in Tetrahedron Letters in 2006.Safety of (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol This article mentions the following:

A novel Sn(IV) aryloxide Lewis acid was designed and prepared from SnCl4 and (S)-3,3′-bis[3,5-bis(trifluoromethyl)phenyl]-1,1′-bi-2-naphthol. The chiral Sn(IV) Lewis acid has been successfully applied to the enantioselective Diels-Alder reaction. In the experiment, the researchers used many compounds, for example, (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol (cas: 863659-89-6Safety of (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol).

(S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol (cas: 863659-89-6) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Safety of (S)-[2,3′:1′,1”:3”,2”’-Quaternaphthalene]-2′,2”-diol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts