Tag: 200-300

《Aliphatic Oxaboroles Enabling Remarkable Recognition of Diols》 was written by Arakawa, Nozomi; Nagao, Kazunori; Murakami, Ryo; Sumida, Yuto; Arakawa, Hiroshi; Inagaki, Fuyuhiko; Ohmiya, Hirohisa. Quality Control of Bis[(pinacolato)boryl]methane And the article was included in Bulletin of the Chemical Society of Japan in 2020. The article conveys some information:

5-Membered ring aliphatic oxaboroles revealed unique characteristics in their reactivity with diols. The aliphatic oxaborole derivatives exhibited a higher complexation activity for Alizarin Red S than phenyl-, alkylboronic acid, benzoxaborole, and oxaborin. Furthermore, the sugar recognition ability depended on the chirality of the aliphatic boroles. In the experiment, the researchers used many compounds, for example, Bis[(pinacolato)boryl]methane(cas: 78782-17-9Quality Control of Bis[(pinacolato)boryl]methane)

Bis[(pinacolato)boryl]methane(cas: 78782-17-9) belongs to organoboron compounds.Quality Control of Bis[(pinacolato)boryl]methane Organoboron compounds are versatile intermediates and as such are some of the most important classes of reagents in modern organic chemistry. This stems from their ease of preparation combined with their ability to undergo a broad range of chemical transformations.

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The author of 《Weak intermolecular interactions in covalent organic framework-carbon nanofiber based crystalline yet flexible devices》 were Mohammed, Abdul Khayum; Vijayakumar, Vidyanand; Halder, Arjun; Ghosh, Meena; Addicoat, Matthew; Bansode, Umesh; Kurungot, Sreekumar; Banerjee, Rahul. And the article was published in ACS Applied Materials & Interfaces in 2019. Quality Control of 2,4,6-Trihydroxybenzene-1,3,5-tricarbaldehyde The author mentioned the following in the article:

The redox-active and porous structural backbone of covalent organic frameworks (COFs) can facilitate high-performance electrochem. energy storage devices. However, the utilities of such 2D materials as supercapacitor electrodes in advanced self-charging power-pack systems have been obstructed due to the poor elec. conductivity and subsequent indigent performance. Herein, the authors report an effective strategy to enhance the elec. conductivity of COF thin sheets through the in situ solid-state inclusion of carbon nanofibers (CNF) into the COF precursor matrix. The obtained COF-CNF hybrids possess a significant intermol. π···π interaction between COF and the graphene layers of the CNF. As a result, these COF-CNF hybrids (DqTp-CNF and DqDaTp-CNF) exhibit good elec. conductivity (0.25 × 10-3 S cm-1), as well as high performance in electrochem. energy storage (DqTp-CNF: 464 mF cm-2 at 0.25 mA cm-2). Also, the fabricated, mech. strong quasi-solid-state supercapacitor (DqDaTp-CNF SC) delivered an ultrahigh device capacitance of 167 mF cm-2 at 0.5 mA cm-2. Furthermore, the authors integrated a monolithic photovoltaic self-charging power pack by assembling DqDaTp-CNF SC with a perovskite solar cell. The fabricated self-charging power pack delivered excellent performance in the areal capacitance (42 mF cm-2) at 0.25 mA cm-2 after photocharging for 300 s. In the experiment, the researchers used 2,4,6-Trihydroxybenzene-1,3,5-tricarbaldehyde(cas: 34374-88-4Quality Control of 2,4,6-Trihydroxybenzene-1,3,5-tricarbaldehyde)

2,4,6-Trihydroxybenzene-1,3,5-tricarbaldehyde(cas: 34374-88-4) is a member of phloroglucinol derivatives. Regarding monomeric phloroglucinols, this group encompasses acryl phloroglucinols, phloroglucinol-terpene adducts, phloroglucinol glycosides, halogenated phloroglucinols, prenylated phloroglucinols, and cyclicroup polyketides.Quality Control of 2,4,6-Trihydroxybenzene-1,3,5-tricarbaldehyde

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The author of 《High Glass-Transition Temperature Polymer Networks Harnessing the Dynamic Ring Opening of Pinacol Boronates》 were Brunet, Juliette; Collas, Franck; Humbert, Matthieu; Perrin, Lionel; Brunel, Fabrice; Lacote, Emmanuel; Montarnal, Damien; Raynaud, Jean. And the article was published in Angewandte Chemie, International Edition in 2019. HPLC of Formula: 24388-23-6 The author mentioned the following in the article:

Differential scanning calorimetry of high molar mass poly(4-vinylphenylboronic acid, pinacol ester)s evidenced unusual reactive events above 120 °C, resulting in a high glass-transition temperature of 220 °C. A reversible ring-opening reactivity of pinacol boronates is proposed, involving a nucleophilic attack on the sp2 boron and subsequent bridging between boron atoms by interconnected pinacol moieties to form a densely crosslinked network with high Tg. FTIR, solid-state NMR investigations, and rheol. studies on the polymer as well as double-tagging analyzes on mol. model structures and theor. calculations further support this hypothesis and indicate a ring-opening inducing crosslinking. When diluted in an apolar solvent such as toluene, the polymer network can be resolubilized via ring closing, thus recovering the entropically favored linear chains featuring cyclic boronate esters. In addition to this study using 4,4,5,5-Tetramethyl-2-phenyl-1,3,2-dioxaborolane, there are many other studies that have used 4,4,5,5-Tetramethyl-2-phenyl-1,3,2-dioxaborolane(cas: 24388-23-6HPLC of Formula: 24388-23-6) was used in this study.

4,4,5,5-Tetramethyl-2-phenyl-1,3,2-dioxaborolane(cas: 24388-23-6) can be used to prepare sulfinamide derivatives by reacting with diethylaminosulfur trifluoride (DAST) and potassium phenyltrifluoroborate.HPLC of Formula: 24388-23-6

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In 2016,Wysoczanska, Kamila; Macedo, Eugenia A. published 《Influence of the Molecular Weight of PEG on the Polymer/Salt Phase Diagrams of Aqueous Two-Phase Systems》.Journal of Chemical & Engineering Data published the findings.Recommanded Product: Potassium sodium (2R,3R)-2,3-dihydroxysuccinate tetrahydrate The information in the text is summarized as follows:

Binodal data for systems composed by polyethylene glycol (PEG) (4000, 6000, or 8000) and salt (potassium citrate, potassium sodium tartrate) were obtained using the cloud point method, at T = 298.15 K. Merchuk equation was applied for the fitting of binodal curves. Tie-lines for systems of PEG (4000, 6000)-potassium citrate and PEG (4000, 6000, 8000)-potassium sodium tartrate were determined by elec. conductivity and lyophilization, and correlated using Othmer-Tobias and Bancroft equations, to verify the reliability of the measured tie-lines. Data were compared with that of previous studies reported in the literature, giving an indication of which system is more efficient in terms of separation, taking into account possible combinations of salt’s cations and PEGs of different mol. weight chosen for ATPS. In the experiment, the researchers used many compounds, for example, Potassium sodium (2R,3R)-2,3-dihydroxysuccinate tetrahydrate(cas: 6381-59-5Recommanded Product: Potassium sodium (2R,3R)-2,3-dihydroxysuccinate tetrahydrate)

Potassium sodium (2R,3R)-2,3-dihydroxysuccinate tetrahydrate(cas: 6381-59-5) is a ferroelectric crystal with a high piezoelectric effect and electromechanical coupling coefficient. Recommanded Product: Potassium sodium (2R,3R)-2,3-dihydroxysuccinate tetrahydrate As a Biuret reagent, it is used to measure the protein concentration. Furthermore, it is used as laxative and is also used in food industry.

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Walker, Shawn D.; Borths, Christopher J.; DiVirgilio, Evan; Huang, Liang; Liu, Pingli; Morrison, Henry; Sugi, Kiyoshi; Tanaka, Masahide; Woo, Jacqueline C. S.; Faul, Margaret M. published an article in Organic Process Research & Development. The title of the article was 《Development of a Scalable Synthesis of a GPR40 Receptor Agonist》.Recommanded Product: (S)-3-(4-Hydroxyphenyl)hex-4-ynoic acid The author mentioned the following in the article:

Early process development and salt selection for AMG 837, a novel GPR40 receptor agonist, is described. The synthetic route to AMG 837 involved the convergent synthesis and coupling of two key fragments, (S)-3-(4-hydroxyphenyl)hex-4-ynoic acid (I) and 3-(bromomethyl)-4′-(trifluoromethyl)biphenyl (II). The chiral β-alkynyl acid I was prepared in 35% overall yield via classical resolution of the corresponding racemic acid (±)-I. An efficient and scalable synthesis of (±)-I was achieved via a telescoped sequence of reactions including the conjugate alkynylation of an in situ protected Meldrum’s acid derived acceptor. The biaryl bromide II was prepared in 86% yield via a 2-step Suzuki-Miyaura coupling-bromination sequence. Chemoselective phenol alkylation mediated by tetrabutylphosphonium hydroxide allowed direct coupling of I and II to afford AMG 837. Due to the poor physiochem. stability of the free acid form of the drug substance, a sodium salt form was selected for early development, and a more stable, crystalline hemicalcium salt dihydrate form was subsequently developed. Overall, the original 12-step synthesis of AMG 837 was replaced by a robust 9-step route affording the target in 25% yield. The experimental part of the paper was very detailed, including the reaction process of (S)-3-(4-Hydroxyphenyl)hex-4-ynoic acid(cas: 865233-35-8Recommanded Product: (S)-3-(4-Hydroxyphenyl)hex-4-ynoic acid)

(S)-3-(4-Hydroxyphenyl)hex-4-ynoic acid(cas: 865233-35-8) belongs to alkynes. The addition of nonpolar E−H bonds across C≡C is general for silanes, boranes, and related hydrides.Recommanded Product: (S)-3-(4-Hydroxyphenyl)hex-4-ynoic acid The hydroboration of alkynes gives vinylic boranes which oxidize to the corresponding aldehyde or ketone. In the thiol-yne reaction the substrate is a thiol.

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The author of 《Synthesis, antibacterial and antifungal activities of bifonazole derivatives》 were El Hage, Salome; Lajoie, Barbora; Feuillolay, Catherine; Roques, Christine; Baziard, Genevieve. And the article was published in Archiv der Pharmazie (Weinheim, Germany) in 2011. Product Details of 63012-03-3 The author mentioned the following in the article:

Two series of chlorinated benzhydryl imidazole and triazole derivatives were synthesized and tested in vitro against representative strains of potent pathogenic bacteria (Staphylococcus aureus CIP 4.83, Enterococcus hirae CIP 5855, Pseudomonas aeruginosa CIP 82118, Escherichia coli CIP 53126) and fungi (Aspergillus niger IP 1431.83, Candida albicans IP 48.72, Candida krusei IP 208.52, Trichophyton rubrum IP 1657.86). Most of these compounds were devoid of any antimicrobial activity, but several of them inhibited T. rubrum with MIC values in the range 0.125-32 μg/mL, similar or superior to those of bifonazole and clotrimazole, used as standard controls. The replacement of the imidazole ring by a triazole moiety in these compounds led to derivatives with less antifungal activity. A preliminary SAR was undertaken on the effect of the number and the position of chlorine atoms on the distribution of neg. charge on the surface of some compounds on antifungal activity. In addition to this study using (3-Chlorophenyl)(phenyl)methanol, there are many other studies that have used (3-Chlorophenyl)(phenyl)methanol(cas: 63012-03-3Product Details of 63012-03-3) was used in this study.

(3-Chlorophenyl)(phenyl)methanol(cas: 63012-03-3) belongs to hydroxy-containing compounds. Hydroxy groups participate in the dehydration reactions that link simple biological molecules into long chains.Product Details of 63012-03-3 The joining of a fatty acid to glycerol to form a triacylglycerol removes the −OH from the carboxy end of the fatty acid.

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In 1994,Bulletin de la Societe Chimique de France included an article by Berkous, Rabia; Dupas, Georges; Bourguignon, Jean; Queguiner, Guy. Recommanded Product: (3-Chlorophenyl)(phenyl)methanol. The article was titled 《Behavior and extension of the scope of NADH models to the reduction of non-activated ketones by a stable indolo NADH model compound in the presence of Lewis acids》. The information in the text is summarized as follows:

The reduction of non-activated ketones, e.g., acetophenone, by a very stable NADH model in the presence of Lewis acids (AlX3, Et2AlCl) is reported. During the reaction, a side equilibrated aldol condensation occurs. Due to the reversibility of this reaction, the overall yield in alc. is not notably diminished. The scope of NADH models has been extended for the first time to non-activated ketones, such as dialkyl, aryl alkyl and diaryl ketones. In the experimental materials used by the author, we found (3-Chlorophenyl)(phenyl)methanol(cas: 63012-03-3Recommanded Product: (3-Chlorophenyl)(phenyl)methanol)

(3-Chlorophenyl)(phenyl)methanol(cas: 63012-03-3) belongs to hydroxy-containing compounds. Hydroxy groups participate in the dehydration reactions that link simple biological molecules into long chains. The joining of a fatty acid to glycerol to form a triacylglycerol removes the −OH from the carboxy end of the fatty acid.Recommanded Product: (3-Chlorophenyl)(phenyl)methanol

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《Iron-Catalyzed C-H Borylation of Arenes》 was written by Dombray, Thomas; Werncke, C. Gunnar; Jiang, Shi; Grellier, Mary; Vendier, Laure; Bontemps, Sebastien; Sortais, Jean-Baptiste; Sabo-Etienne, Sylviane; Darcel, Christophe. Related Products of 401797-00-0 And the article was included in Journal of the American Chemical Society on April 1 ,2015. The article conveys some information:

Well-defined iron bis(diphosphine) complexes are active catalysts for the dehydrogenative C-H borylation of aromatic and heteroaromatic derivatives with pinacolborane. The corresponding borylated compounds were isolated in moderate to good yields (25-73%) with a 5 mol% catalyst loading under UV irradiation (350 nm) at room temperature Stoichiometric reactivity studies and isolation of an original trans-hydrido(boryl)iron complex, Fe(H)(Bpin)(dmpe)2, allowed us to propose a mechanism showing the role of some key catalytic species. In addition to this study using 2-(3,4-Dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, there are many other studies that have used 2-(3,4-Dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(cas: 401797-00-0Related Products of 401797-00-0) was used in this study.

2-(3,4-Dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(cas: 401797-00-0) belongs to hydroxy-containing compounds. Hydroxy groups participate in the dehydration reactions that link simple biological molecules into long chains. The joining of a fatty acid to glycerol to form a triacylglycerol removes the −OH from the carboxy end of the fatty acid.Related Products of 401797-00-0

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《Chromic acid oxidation of benzhydrols – kinetics and mechanism》 was published in Australian Journal of Chemistry in 1977. These research results belong to Ramanujam, V. M. Sadagopa; Venkatasubramanian, N.; Sundaram, S.. SDS of cas: 63012-03-3 The article mentions the following:

The kinetics of the oxidation of Ph2CHOH and several derivatives by chromium(VI) oxide in aqueous AcOH were studied. The rate of oxidation is expressed as: υ = k3[ArAr’CHOH][CrVI][H+]2. The effect of ring substituents on the rate gives a ρ+ value of -0.546 (r = 0.959) pointing to the development of an electron-deficient centre in the transition state. The oxidation of Ph2CDOH proceeds 6.5 times slower than that of its H analog at 55°C. From the Arrhenius plots, activation parameters were evaluated and the isokinetic relationship was analyzed. The results are discussed in terms of a mechanism involving a rate-determining loss of hydride ion from the α-carbon of benzhydroxy chromate ester. In addition to this study using (3-Chlorophenyl)(phenyl)methanol, there are many other studies that have used (3-Chlorophenyl)(phenyl)methanol(cas: 63012-03-3SDS of cas: 63012-03-3) was used in this study.

(3-Chlorophenyl)(phenyl)methanol(cas: 63012-03-3) belongs to hydroxy-containing compounds. Hydroxy-containing compounds engage in intermolecular hydrogen bonding increasing the electrostatic attraction between molecules and thus to higher boiling and melting points than found for compounds that lack this functional group.SDS of cas: 63012-03-3 Organic compounds, which are often poorly soluble in water, become water-soluble when they contain two or more hydroxy groups, as illustrated by sugars and amino acid.

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Safety of Bis[(pinacolato)boryl]methaneIn 2018 ,《Enantioselective Construction of Tertiary Boronic Esters by Conjunctive Cross-Coupling》 was published in Angewandte Chemie, International Edition. The article was written by Myhill, Jesse A.; Zhang, Liang; Lovinger, Gabriel J.; Morken, James P.. The article contains the following contents:

Catalytic enantioselective conjunctive cross-coupling has been developed to construct tertiary alkylboronic esters. These reactions occur with good yield and enantioselectivity for a range of substrates. Mechanistic experiments reveal aspects of the catalytic cycle that allow hindered substrates to react without significant complicating side reactions. After reading the article, we found that the author used Bis[(pinacolato)boryl]methane(cas: 78782-17-9Safety of Bis[(pinacolato)boryl]methane)

Bis[(pinacolato)boryl]methane(cas: 78782-17-9) belongs to organoboron compounds.Safety of Bis[(pinacolato)boryl]methane Organoboron compounds have been a cornerstone of synthetic transformations for decades. Areas such as boron-containing catalysts, metalate chemistry, photoredox methods, and boryl anions have brought significant new developments in understanding and provided new reactivity upon.

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