Tag: 100-200

Electron in a cube: synthesis and characterization of perfluorocubane as an electron acceptor was written by Sugiyama, Masafumi; Akiyama, Midori; Yonezawa, Yuki; Komaguchi, Kenji; Higashi, Masahiro; Nozaki, Kyoko; Okazoe, Takashi. And the article was included in Science (Washington, DC, United States) on August 12,2022.Computed Properties of C10H12O2 The following contents are mentioned in the article:

The synthesis and characterization of perfluorocubane, a stable polyhedral fluorocarbon was reported. The key to the successful synthesis was the efficient introduction of multiple fluorine atoms to cubane by liquid-phase reaction with fluorine gas. The solid-state structure of perfluorocubane was confirmed using x-ray crystallog., and its electron-accepting character was corroborated electrochem. and spectroscopically. The radical anion of perfluorocubane was examined by matrix-isolation ESR spectroscopy, which revealed that the unpaired electron accepted by perfluorocubane is located predominantly inside the cage. This study involved multiple reactions and reactants, such as Cubane-1,4-diyldimethanol (cas: 60462-27-3Computed Properties of C10H12O2).

Cubane-1,4-diyldimethanol (cas: 60462-27-3) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Computed Properties of C10H12O2

60462-27-3;Cubane-1,4-diyldimethanol;The future of 60462-27-3;New trend of C10H12O2;function of 60462-27-3

Alkynylcubanes as Precursors of Rigid-Rod Molecules and Alkynylcyclooctatetraenes was written by Eaton, Philip E.; Galoppini, Elena; Gilardi, Richard. And the article was included in Journal of the American Chemical Society on August 24,1994.COA of Formula: C10H12O2 The following contents are mentioned in the article:

The authors have developed new methodol. for the synthesis of alkynylcubanes and have used these compounds to make rigid-rod mols. constructed of cubane and acetylene subunits. Terminal and substituted alkynylcubanes, e.g., ethynylcubane, were synthesized by n-BuLi-promoted elimination of halogen from dibromovinylcubanes, e.g., (2,2-dibromovinyl)cubane, followed by quenching with electrophiles. Systems with one or two acetylenic units between two cubanes were also prepared Dimerizations and cross-coupling reactions of various 1,4-diethynylcubanes afforded longer rods. This study involved multiple reactions and reactants, such as Cubane-1,4-diyldimethanol (cas: 60462-27-3COA of Formula: C10H12O2).

Cubane-1,4-diyldimethanol (cas: 60462-27-3) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.COA of Formula: C10H12O2

60462-27-3;Cubane-1,4-diyldimethanol;The future of 60462-27-3;New trend of C10H12O2;function of 60462-27-3

Synthesis and structures of 1,4-bis(chloromethyl)-and 1,4-bis(bromomethyl)cubanes was written by Shastin, A. V.; Romanova, L. B.; Eremenko, L. T.; Zakharov, V. V.; Lagodzinskaya, G. V.; Aleksandrov, G. G.; Eremenko, I. L.. And the article was included in Russian Chemical Bulletin on August 31,2006.Recommanded Product: Cubane-1,4-diyldimethanol The following contents are mentioned in the article:

1,4-Bis(chloromethyl)cubane (I) and 1,4-bis(bromomethyl)cubane (II) were synthesized by the reactions of triphenylphosphine with CCl4 and NBS, resp. The structures of the compounds were studied by X-ray diffraction anal. of I [monoclinic, P2(1)/c, a 6.035(12), b 7.365(17), c 11.49(3) Å, β 104.67(10)°, V 494(2) Å3, Z 2] and II [monoclinic, P2(1)/c, a 5.332(3), b 11.074(7), c 7.787(4) Å, β 105.83(4)°, V 442.3(4) Å3, Z 2]. This study involved multiple reactions and reactants, such as Cubane-1,4-diyldimethanol (cas: 60462-27-3Recommanded Product: Cubane-1,4-diyldimethanol).

Cubane-1,4-diyldimethanol (cas: 60462-27-3) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Recommanded Product: Cubane-1,4-diyldimethanol

60462-27-3;Cubane-1,4-diyldimethanol;The future of 60462-27-3;New trend of C10H12O2;function of 60462-27-3

Synthesis of 4-bromocubane-1-carboxaldehyde was written by Shastin, A. V.; Zakharov, V. V.; Bugaeva, G. P.; Eremenko, L. T.; Romanova, L. B.; Lagodzinskaya, G. V.; Aleksandrov, G. G.; Eremenko, I. L.. And the article was included in Russian Chemical Bulletin on July 31,2006.Product Details of 60462-27-3 The following contents are mentioned in the article:

Oxidation of 4-bromo-1-(hydroxymethyl)cubane and 1,4-bis(hydroxymethyl)cubane with the 2,2,6,6-tetramethylpiperidine N-oxyl-trichloroisocyanuric acid-sodium bicarbonate system afforded the corresponding aldehydes (I; Y = Br, CHO). 4-Bromocubanecarboxaldehyde was also obtained in high yield by reduction of 4-bromocubanecarboxylic acid and its Me ester with bis(N-methylpiperazinyl)aluminum hydride. This study involved multiple reactions and reactants, such as Cubane-1,4-diyldimethanol (cas: 60462-27-3Product Details of 60462-27-3).

Cubane-1,4-diyldimethanol (cas: 60462-27-3) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Product Details of 60462-27-3

60462-27-3;Cubane-1,4-diyldimethanol;The future of 60462-27-3;New trend of C10H12O2;function of 60462-27-3

3.* Synthesis and molecular structure of 1,4-bis(hydroxymethyl)cubane was written by Zakharov, V. V.; Bugaeva, G. P.; Ivanova, M. E.; Romanova, L. B.; Eremenko, L. T.; Nefedov, S. E.; Eremenko, I. L.. And the article was included in Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya) on July 31,1998.Related Products of 60462-27-3 The following contents are mentioned in the article:

An efficient procedure for the preparation of 1,4-bis(hydroxymethyl)cubane by reduction of 1,4-cubanedicarboxylic acid or its di-Me ester with aluminum hydride was developed. The mol. structure of 1,4-bis(hydroxymethyl)cubane was established by X-ray diffraction anal. This study involved multiple reactions and reactants, such as Cubane-1,4-diyldimethanol (cas: 60462-27-3Related Products of 60462-27-3).

Cubane-1,4-diyldimethanol (cas: 60462-27-3) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Related Products of 60462-27-3

60462-27-3;Cubane-1,4-diyldimethanol;The future of 60462-27-3;New trend of C10H12O2;function of 60462-27-3

Unravelling the nature of binding of cubane and substituted cubanes within cucurbiturils: A DFT and NCI study was written by Venkataramanan, Natarajan Sathiyamoorthy; Suvitha, Ambigapathy; Kawazoe, Yoshiyuki. And the article was included in Journal of Molecular Liquids on June 15,2018.SDS of cas: 60462-27-3 The following contents are mentioned in the article:

The nature of interactions between the neutral, charged and substituted cubane, within cucurbituril host were analyzed employing the dispersion corrected d. functional theory. The structural comparison between the inclusion complexes of CB7 and CB8 shows a best fit for the CB7. The computed Gibbs free energy for the formation of inclusion complexes by the neutral guests were close to the exptl. estimate The dicationic guest within CB has the highest strain energy with least strain on the host. The conceptual DFT based anal. ECT anal. shows a charge transfer from the host to guest in neutral systems, while for the dicationic guest an electron transfer from guest to host has been noticed, which was further conformed from the quant. MESP values. The computed NICS values on the cubane, are not affected by the introduction of charge/substituents implying that cubane part act as a spacer group while the functional groups present on the cubane dictates the charge transfer. In AIM anal., the ρ value is least for the complex cubane@CB7 and highest for the cubane functionalized dicationic complex@CB complexes. The NCI-RDG anal. for the inclusion complex with dicarboxylic guest, the spike at higher d. region undergoes a shift, reflecting the increase in repulsive energy. In the inclusion complexes of CB7 the patch escalation in the NCI isosurface occurs evenly in CB7 than on the CB8 inclusion complexes, signifying the fit-induced extra stability of the CB7 inclusion complexes. EDA anal. shows that the Pauli repulsive energy increase with the increase in the size of the guest mol. and among the guest the dicationic has the highest repulsive energy. The presence of higher amount of electrostatic interactions in the dicationic complex has remunerated the dispersion contribution in the dicationic complexes. This study involved multiple reactions and reactants, such as Cubane-1,4-diyldimethanol (cas: 60462-27-3SDS of cas: 60462-27-3).

Cubane-1,4-diyldimethanol (cas: 60462-27-3) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.SDS of cas: 60462-27-3

60462-27-3;Cubane-1,4-diyldimethanol;The future of 60462-27-3;New trend of C10H12O2;function of 60462-27-3

Application In Synthesis of (4-Bromophenyl)methanolIn 2019 ,《Iridium Supported on Phosphorus-Doped Porous Organic Polymers: Active and Recyclable Catalyst for Acceptorless Dehydrogenation and Borrowing Hydrogen Reaction》 appeared in Advanced Synthesis & Catalysis. The author of the article were Yao, Wei; Duan, Zheng-Chao; Zhang, Yilin; Sang, Xinxin; Xia, Xiao-Feng; Wang, Dawei. The article conveys some information:

Iridium-on-phosphorus-doped porous organic polymers (POP-Ir) were developed by anchoring simple iridium onto the skeleton of porous organic polymers through coordination bonds. This POP-Ir catalyst, which was thoroughly characterized by means of EDS, SEM, TEM, XRD, XPS, and FT-IR, revealed excellent catalytic activity for the reaction of di-Ph phosphinamide with benzyl alcs. through borrowing hydrogen strategy and acceptorless dehydrogenation with wide functional group tolerance. Moreover, this POP-Ir catalyst could be simply recovered and reused for at least five times without a significant loss of activity, and revealed considerable application prospects. The mechanism was investigated to further understand this POP-Ir catalytic system and transformations. Overall, the POP-Ir catalytic system has shown high activity and reusability in the borrowing hydrogen reaction between di-Ph phosphinamides and benzyl alcs. In the experiment, the researchers used (4-Bromophenyl)methanol(cas: 873-75-6Application In Synthesis of (4-Bromophenyl)methanol)

(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.Application In Synthesis of (4-Bromophenyl)methanol It undergoes efficient trimethylsilylation reaction with 1,1,1,3,3,3-hexamethyldisilazane in the presence of catalytic amount of aspartic acid in acetonitrile.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2022,Xia, Lei; Tian, Jia; Yue, Tao; Cao, Hongliang; Chu, Ju; Cai, Haibo; Zhang, Weian published an article in Advanced Healthcare Materials. The title of the article was 《Pillar[5]arene-Based Acid-Triggered Supramolecular Porphyrin Photosensitizer for Combating Bacterial Infections and Biofilm Dispersion》.Synthetic Route of C6H15NO The author mentioned the following in the article:

The treatment of pathogenic bacterial infection has long been the most serious threat to human life and attracted widespread attention. Herein, a supramol. photosensitizer platform based on carboxylatopillar[5]arene (CP5) and tetrafluorophenyl porphyrin functionalized with a quaternary ammonium group (TFPP-QA) for combating bacteria and dispersing biofilm via photodynamic treatment is constructed. By introducing the host macrocycle CP5 and host-guest interaction, the supramol. photosensitizer has great biocompatibility and acid responsiveness. On the one hand, the acid-triggered dissociation of TFPP-QA/CP5 could induce the porphyrin photosensitizer to target bacterial cells and disrupt the charge balance of bacterial membranes, enhance the permeability of the bacterial membrane. On the other hand, the TFPP-QA/CP5 antibacterial platform possesses superb reactive oxygen species (ROS) generation capability under light irradiation, leading to enhanced photodynamic antibacterial efficacy. The in vitro and in vivo studies show that the supramol. photosensitizers exhibit high antibacterial efficiency and biofilm dissipation effect under 660 nm light irradiation Therefore, it is anticipated that the rational design and integration of photosensitizers and quaternary ammonium compounds through the supramol. strategy would provide a promising prospect for clin. photodynamic antimicrobial therapy. The experimental part of the paper was very detailed, including the reaction process of 6-Aminohexan-1-ol(cas: 4048-33-3Synthetic Route of C6H15NO)

6-Aminohexan-1-ol(cas: 4048-33-3) can undergo cyclization over copper supported on γ-alumina and magnesia to form hexahydro-1H-azepine. It may be used along with glutaric acid to generate poly(ester amide)s with excellent film- and fiber forming properties.Synthetic Route of C6H15NO

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2022,Balakrishnan, Venkadesh; Ganguly, Anirban; Rasappan, Ramesh published an article in Organic Letters. The title of the article was 《Interception of Nickel Hydride Species and Its Application in Multicomponent Reactions》.Recommanded Product: 100-55-0 The author mentioned the following in the article:

The hydrogen borrowing strategy is an economical method for the α-functionalization of ketones. While this strategy is extremely advantageous, it does not lend itself to the synthesis of β,β-disubstituted ketones. This can be achieved, if the in situ generated metal hydride can be intercepted with a nucleophilic coupling partner. Authors present a multicomponent strategy for the coupling of alcs., ketones, and boronic acids using only 1 mol % nickel catalyst and without the need for added ligands. In the experimental materials used by the author, we found 3-Pyridinemethanol(cas: 100-55-0Recommanded Product: 100-55-0)

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridine is a relatively complex molecule and exhibits a number of different bands in IR spectra. Among others, the bands characterizing the ν8a and ν19b modes have been found to be sensitive to the coordination or protonation of the molecule. Note that the band that is diagnostic for the PyH+ ion at about 1545 cm− 1 (ν19b mode) does not overlap with any of the other bands.Recommanded Product: 100-55-0

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2022,Chen, Su; Van der Eycken, Erik V.; Sharma, Upendra K. published an article in Advanced Synthesis & Catalysis. The title of the article was 《Remote Alkenylation via Carbopalladation/1,4-Palladium Migration/Heck Reaction Sequence with Unactivated Alkenyl Alcohols》.Recommanded Product: 821-41-0 The author mentioned the following in the article:

Intramol. C-H bond activation via 1,4-palladium migration has become a synthetic tool to enable remote functionalization of C-H bonds. In this work, authors report a Pd-catalyzed remote alkenylation with unactivated alkenyl alcs. involving a 1,4-palladium migration step. This method provides a regioselective access to synthesize substituted unsaturated alcs. in a single operational step. The results came from multiple reactions, including the reaction of 5-Hexen-1-ol(cas: 821-41-0Recommanded Product: 821-41-0)

5-Hexen-1-ol(cas: 821-41-0) is used in cyclization to a tetrahydropyran by phenylselenoetherification. It is also used as a building block in synthetic chemistry.Recommanded Product: 821-41-0

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts