Tag: 100-200

The author of 《Development and mechanistic investigation of the manganese(III) salen-catalyzed dehydrogenation of alcohols》 were Samuelsen, Simone V.; Santilli, Carola; Ahlquist, Maarten S. G.; Madsen, Robert. And the article was published in Chemical Science in 2019. Safety of (4-Bromophenyl)methanol The author mentioned the following in the article:

The first example of a manganese(III) catalyst for the acceptorless dehydrogenation of alcs. was presented. N,N’-Bis(salicylidene)-1,2-cyclohexanediaminomanganese(III) chloride was shown to catalyzed the direct synthesis of imines from a variety of alcs. and amines with the liberation of hydrogen gas. The mechanism was investigated exptl. with labeled substrates and theor. with DFT calculations The results indicated a metal-ligand bifunctional pathway in which both imine groups in the salen ligand are first reduced to form a manganese(III) amido complex as the catalytically active species. Dehydrogenation of the alc. then takes place by a stepwise outer-sphere hydrogen transfer generating a manganese(III) salan hydride from which hydrogen gas was released. In the experiment, the researchers used many compounds, for example, (4-Bromophenyl)methanol(cas: 873-75-6Safety of (4-Bromophenyl)methanol)

(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.Safety of (4-Bromophenyl)methanol It undergoes oxidation reaction in the presence of polyvinylpolypyrrolidone-supported hydrogen peroxide, silica sulfuric acid and ammonium bromide to yield 4-bromobenzaldehyde.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

The author of 《Manganese(I)-Catalyzed α-Alkenylation of Ketones Using Primary Alcohols》 were Gawali, Suhas Shahaji; Pandia, Biplab Keshari; Gunanathan, Chidambaram. And the article was published in Organic Letters in 2019. Recommanded Product: (4-Bromophenyl)methanol The author mentioned the following in the article:

A simple protocol of manganese catalyzed selective α-alkenylation of ketones using primary alcs. is reported. The reactions proceeded well with a low loading of catalyst (0.3 mol%). The overall transformation operates through O-H bond activation of primary alcs. via dearomatization-aromatization metal ligand cooperation in the catalyst to provide the corresponding aldehydes, which further undergo condensation with methylene ketones to deliver α,β-unsaturated ketones. This selective α-alkenylation proceeds with the release of water and liberation of mol. hydrogen. In the experiment, the researchers used many compounds, for example, (4-Bromophenyl)methanol(cas: 873-75-6Recommanded Product: (4-Bromophenyl)methanol)

(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.Recommanded Product: (4-Bromophenyl)methanol It undergoes oxidation reaction in the presence of polyvinylpolypyrrolidone-supported hydrogen peroxide, silica sulfuric acid and ammonium bromide to yield 4-bromobenzaldehyde.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Feng; Niu, Yujie; Hong, Dacheng; Ye, Yilin; Hua, Yuhui; Ding, Shihao; Zhang, Yandong published an article on February 28 ,2021. The article was titled 《Synthetic studies towards atkamine》, and you may find the article in Chinese Chemical Letters.Application In Synthesis of 4,4-Diethoxybutan-1-amine The information in the text is summarized as follows:

Atkamine (I) is a complex marine pyrroloiminoquinone alkaloid that comprises a heptacyclic scaffold bearing five different heterocycles and four contiguous stereocenters, and therefore it is a highly challenging target for synthetic chemists. We herein reported a modular synthetic strategy toward this alkaloid, featuring a formal [5 + 2] annulation and an asym. Michael addition The efficient synthesis of the long-chain aliphatic aldehyde and chiral amino acetal fragments have been achieved. A simplified tetracyclic intermediate bearing the core structure of atkamine has been successfully constructed through the formal [5 + 2] annulation. In the experiment, the researchers used 4,4-Diethoxybutan-1-amine(cas: 6346-09-4Application In Synthesis of 4,4-Diethoxybutan-1-amine)

4,4-Diethoxybutan-1-amine(cas: 6346-09-4) belongs to anime. Milder oxidation, using reagents such as NaOCl, can remove four hydrogen atoms from primary amines of the type RCH2NH2 to form nitriles (R―C≡N), and oxidation with reagents such as MnO2 can remove two hydrogen atoms from secondary amines (R2CH―NHR′) to form imines (R2C=NR′). Tertiary amines can be oxidized to enamines (R2C=CHNR2) by a variety of reagents.Application In Synthesis of 4,4-Diethoxybutan-1-amine

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Usuki, Toyonobu; Komatsu, Akira published an article in Tetrahedron Letters. The title of the article was 《Preparation of monoalkylpiperidines via the mild hydrogenation of monoalkynylpyridines》.Recommanded Product: 93524-95-9 The author mentioned the following in the article:

Monoalkynylpyridines were prepared via a Sonogashira cross-coupling reaction between monoiodopyridines and alkynes. From the obtained monoalkynylpyridines, mild hydrogenation was conducted to produce the corresponding monoalkylpiperidines in moderate to excellent yields. The hydrogenation reaction was carried out under H2(1 atm) in the presence of 10 wt% Pd/C (5 equiv) in either AcOH or MeOH at room temperature Therefore, this mild method was useful for the quick and easy preparation of monoalkylpiperidines. The results came from multiple reactions, including the reaction of 3-(4-Pyridyl)-2-propyn-1-ol(cas: 93524-95-9Recommanded Product: 93524-95-9)

3-(4-Pyridyl)-2-propyn-1-ol(cas: 93524-95-9) belongs to pyridine. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. As ligands, solvents, and catalysts they facilitate reactions; thus descriptions of these new ligands and their applications abound each year.Recommanded Product: 93524-95-9

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Alcohol – Wikipedia,
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Nachtigall, Carsten; Berger, Christiane; Kovanovic, Tijana; Wefers, Daniel; Jaros, Doris; Rohm, Harald published their research in Food Hydrocolloids on December 31 ,2019. The article was titled 《Shear induced molecular changes of exopolysaccharides from lactic acid bacteria》.Electric Literature of C6H12O6 The article contains the following contents:

Exopolysaccharide (EPS) producing lactic acid bacteria are known for their pos. effect on the texture of fermented dairy products, with their high water binding capacity causing changes in rheol. and syneresis reduction During manufacture, product texture is affected by shearing with an unknown impact on the properties of the EPS. By subjecting aqueous solutions of viscosity enhancing EPS from Streptococcus thermophilus DGCC7710 or dextran to defined shear treatments with a Microfluidizer, a cell disruption system or a toothed ring dispersion unit to apply different energy input, we investigated macromol. properties and the behavior in solution Despite the breakage of covalent bonds, spectroscopic NMR analyses revealed that repeating unit structure remained unchanged, whereas changes in macromol. properties such as intrinsic viscosity, hydrodynamic volume, and mol. mass strongly depended on energy input. The decrease of the dynamic viscosity of the polysaccharide solutions was significantly related to the observed decrease in mol. mass, and the impact of the EPS on technofunctional properties such as contribution to gel stiffness during acid gel formation was also affected. The results therefore indicate that mech. energy input through shearing should be considered because product texture may be altered as a consequence of a mech. breakdown of EPS mols. The experimental part of the paper was very detailed, including the reaction process of rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol(cas: 54-17-1Electric Literature of C6H12O6)

rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol(cas: 54-17-1) is oxidized in various tissues under either aerobic or anaerobic conditions through glycolysis; the oxidation reaction produces carbon dioxide, water, and ATP.Electric Literature of C6H12O6

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Alcohol – Wikipedia,
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In 2003,Tetrahedron Letters included an article by Mourtas, Spyros; Katakalou, Christina; Nicolettou, Andriana; Tzavara, Chryssoula; Gatos, Dimitrios; Barlos, Kleomenis. Related Products of 31110-78-8. The article was titled 《Resin-bound aminothiols: synthesis and application》. The information in the text is summarized as follows:

Aminothiols were attached through their thiol group onto the 4,4′-dimethoxytrityl (Dmt)-, 4-methoxytrityl (Mmt)-, 4-methyltrityl (Mtt)-, trityl (Trt)- and 2-chlorotrityl (Clt)-resins. The new resins were used in the solid-phase synthesis of aminothiol containing peptides utilizing N-Fmoc amino acids. The synthesized peptides were cleaved from the resins by treatment with trifluoroacetic acid (TFA) solutions using triethylsilane (TES) or ethanedithiol (EDT) as scavengers. The results came from multiple reactions, including the reaction of 5-Aminopentane-1-thiol hydrochloride(cas: 31110-78-8Related Products of 31110-78-8)

5-Aminopentane-1-thiol hydrochloride(cas: 31110-78-8) belongs to thiols. Thiols show many reactions like those of the hydroxyl compounds, such as formation of thioesters and thioethers (sulfides).Related Products of 31110-78-8 Toward oxidation, however, they differ profoundly from alcohols: whereas oxidation of an alcohol usually leads to a product in which the oxidation state of a carbon atom has been changed, oxidation of a thiol affects the sulfur atom.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Burcat, Alexander published their research in Combustion and Flame on December 31 ,2020. The article was titled 《Thermochemistry of computed gaseous energetic compounds: Cellulose nitrate》.Application In Synthesis of rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol The article contains the following contents:

The thermochem. of gaseous Cellulose, Cellulosedinitrate and Cellulosetrinitrate basic cells, was calculated and is presented as numerical values and as NASA-7-term polynomials. The problem of representing and calculating thermochem. values of cell polymers is discussed. In the experiment, the researchers used rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol(cas: 54-17-1Application In Synthesis of rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol)

rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol(cas: 54-17-1) is the monohydrate form of the alpha isoform of D-glucopyranose, a synthetic simple monosaccharide that is used as an energy source.Application In Synthesis of rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Product Details of 2525-05-5On March 31, 1979, Hulisz, Stanislaw; Wawek, Janina published an article in Przemysl Chemiczny. The article was 《Study on the effectiveness of inhibiting furfural autoxidation》. The article mentions the following:

Furfural autoxidation was inhibited by adding 0.01 weight% p-HOC6H4NH2, N(CH2CH2OH)3, 3,4-(HO)2C6H3Bu, HCONH2 or p-(HO)2C6H4. The effectiveness of the additives decreased in the stated order of compounds; the 1st 3 are recommended. The experimental part of the paper was very detailed, including the reaction process of 4-Butylbenzene-1,2-diol(cas: 2525-05-5Product Details of 2525-05-5)

4-Butylbenzene-1,2-diol(cas: 2525-05-5) belongs to organoboron compounds. Organoboron compounds are versatile intermediates and as such are some of the most important classes of reagents in modern organic chemistry. Organoboron compounds are less toxic than organostannane reagents, and unlike alkynylzinc and magnesium, many organoboron compounds possess remarkable oxidative and thermal stabilities. Product Details of 2525-05-5

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Alcohol – Wikipedia,
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《Synthesis of a series of M(II) (M = Mn, Fe, Co) chloride complexes with both inter- and intra-ligand hydrogen bonding interactions》 was written by Leahy, Clare A.; Drummond, Michael J.; Vura-Weis, Josh; Fout, Alison R.. Quality Control of 2-Hydroxyphenylboronic acidThis research focused ontransition metal chloro pyrrolyl pyridyl phenolate complex preparation; crystal structure transition metal chloro pyrrolyl pyridyl phenolate complex. The article conveys some information:

Hydrogen bonding networks are vital for metalloenzymes to function; however, modeling these systems is non-trivial. The authors report the synthesis of metal chloride (M = Mn, Fe, Co) complexes with intra- and inter-ligand hydrogen bonding interactions. The intra-ligand hydrogen bonds have a profound effect on the geometry of the metal center. In the part of experimental materials, we found many familiar compounds, such as 2-Hydroxyphenylboronic acid(cas: 89466-08-0Quality Control of 2-Hydroxyphenylboronic acid)

2-Hydroxyphenylboronic acid(cas: 89466-08-0) belongs to acyl phenylboronic acid. Phenylboronic acid (PBA), a synthetic molecule applied in RNA affinity chromatography, is able to form reversible covalent ester bonds with 1,2- or 1,3-cis-doils on the ribose ringQuality Control of 2-Hydroxyphenylboronic acid

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《Structure-function studies of the aminothiol radioprotectants. Effect of carbon chain length in mercaptoethylamine homologs. Mammalian radioprotection》 was published in Radiation Research in 1971. These research results belong to Grenan, Marie M.; Copeland, Edmund S.. Safety of 5-Aminopentane-1-thiol hydrochloride The article mentions the following:

Of the 5 aminothiols (I) studied, only β-mercaptoethylamine-HCl (II) (0.7 mM/kg, i.p.) showed a radioprotective effect in mice treated with an LD70(30) radiation dose (875 rads). This result is in contrast to those of previous studies in bacteria where pharmacological effects were avoided and only phys.-chem. effects were studied. In the experiment, the researchers used many compounds, for example, 5-Aminopentane-1-thiol hydrochloride(cas: 31110-78-8Safety of 5-Aminopentane-1-thiol hydrochloride)

5-Aminopentane-1-thiol hydrochloride(cas: 31110-78-8) belongs to thiols. Thiols show many reactions like those of the hydroxyl compounds, such as formation of thioesters and thioethers (sulfides). Toward oxidation, however, they differ profoundly from alcohols: whereas oxidation of an alcohol usually leads to a product in which the oxidation state of a carbon atom has been changed, oxidation of a thiol affects the sulfur atom. Safety of 5-Aminopentane-1-thiol hydrochloride

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts