Tag: 100-200

Quality Control of 3,5-DihydroxybenzaldehydeIn 2022 ,《Preparation of a resveratrol-ascorbic acid mem conjugate》 appeared in Heterocyclic Letters. The author of the article were Amin, Rasidul; Hunt, David A.. The article conveys some information:

The preparation of a resveratrol-ascorbic acid conjugate in support of pharmacodynamic and pharmacokinetic studies has been achieved through a seven-step convergent synthesis. In addition to this study using 3,5-Dihydroxybenzaldehyde, there are many other studies that have used 3,5-Dihydroxybenzaldehyde(cas: 26153-38-8Quality Control of 3,5-Dihydroxybenzaldehyde) was used in this study.

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is a building block. It has been used in the synthesis of 2,4-dimethylbenzoylhydrazones with antileishmanial and antioxidant activities.Quality Control of 3,5-Dihydroxybenzaldehyde

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

COA of Formula: C7H6O2In 2019 ,《Multicomponent synthesis of pyrano[2,3-d]pyrimidine derivatives via a direct one-pot strategy executed by novel designed copperated Fe3O4@polyvinyl alcohol magnetic nanoparticles》 appeared in Materials Today Chemistry. The author of the article were Maleki, A.; Niksefat, M.; Rahimi, J.; Taheri-Ledari, R.. The article conveys some information:

A magnetic nanocatalyst system was designed and used for facilitating one-pot synthesis of pyrano[2,3-d]pyrimidine derivatives I (R = Ph, 2,4-dichlorophenyl, 2-thienyl, etc.). This product takes advantages of copper(II) ions chelated with oxygen atoms of polyvinyl alc. (PVA) strands, which were well composited with iron oxide magnetic nanoparticles during an in situ process. High reaction yields were obtained by using this efficient nanocatalyst in the short times and under mild conditions. High hydrophilicity, convenient separation, and acceptable recyclability have been investigated and introduced as the features of this nanocatalyst. Structural studies related to the nanoscale materials have also been carried out and well interpreted in this report. In the experiment, the researchers used many compounds, for example, 3-Hydroxybenzaldehyde(cas: 100-83-4COA of Formula: C7H6O2)

3-Hydroxybenzaldehyde(cas: 100-83-4) is used as an ionophore, during the development of an highly selective and sensitive PVC membrane sensor, which can be used as a Tb3+ ion selective electrode.COA of Formula: C7H6O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Safety of 3,5-DihydroxybenzaldehydeIn 2021 ,《Design and microwave synthesis of new (5Z) 5-arylidene-2-thioxo-1,3-thiazolinidin-4-one and (5Z) 2-amino-5-arylidene-1,3-thiazol-4(5H)-one as new inhibitors of protein kinase DYRK1A》 appeared in Pharmaceuticals. The author of the article were Bourahla, Khadidja; Guiheneuf, Solene; Limanton, Emmanuelle; Paquin, Ludovic; Le Guevel, Remy; Charlier, Thierry; Rahmouni, Mustapha; Durieu, Emilie; Lozach, Olivier; Carreaux, Francois; Meijer, Laurent; Bazureau, Jean-Pierre. The article conveys some information:

Here, we report on the synthesis of libraries of new 5-arylidene-2-thioxo-1,3-thiazolidin-4-ones 3 (twenty-two compounds) and new 2-amino-5-arylidene-1,3-thiazol-4(5H)-ones 5 (twenty-four compounds) with stereo controlled Z-geometry under microwave irradiation The 46 designed final compounds were tested in order to determine their activity against four representative protein kinases (DYR1A, CK1, CDK5/p25, and GSK3α/β). Among these 1,3-thiazolidin-4-ones, the mols. (5Z) 5-(4-hydroxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one 3e (IC50 0.028 μM) and (5Z)-5-benzo[1,3]dioxol-5-ylmethylene-2-(pyridin-2-yl)amino-1,3-thiazol-4(5H)-one 5s (IC50 0.033 μM) were identified as lead compounds and as new nanomolar DYRK1A inhibitors. Some of these compounds in the two libraries have been also evaluated for their in vitro inhibition of cell proliferation (Huh7 D12, Caco2, MDA-MB 231, HCT 116, PC3, and NCI-H2 tumor cell lines). These results will enable us to use the 1,3-thiazolidin-4-one core as pharmacophores to develop potent treatment for neurol. or oncol. disorders in which DYRK1A is fully involved. In the experiment, the researchers used 3,5-Dihydroxybenzaldehyde(cas: 26153-38-8Safety of 3,5-Dihydroxybenzaldehyde)

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is a building block. It has been used in the synthesis of 2,4-dimethylbenzoylhydrazones with antileishmanial and antioxidant activities.Safety of 3,5-Dihydroxybenzaldehyde

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

HPLC of Formula: 1195-59-1In 2019 ,《Regulation of magnetic relaxation behavior by replacing 3d transition metal ions in [M2Dy2] complexes containing two different organic chelating ligands》 appeared in Dalton Transactions. The author of the article were Wang, Hui-Sheng; Yin, Cheng-Ling; Hu, Zhao-Bo; Chen, Yong; Pan, Zhi-Quan; Song, You; Zhang, Yi-Quan; Zhang, Zai-Chao. The article conveys some information:

Four tetranuclear 3d-4f complexes, namely [Fe2Ln2(L)2(teaH)2(Cl)2](NO3)2·4CH3CN (H2L = N1,N3-bis(3-methoxysalicylidene)diethylenetriamine, teaH3 = triethanolamine, Ln = Dy for 1 and Ln = Gd for 1′) and [Co2Ln2(L)2(pdm)2(CH3COO)2(CH3OH)2](NO3)2·xCH3OH·yH2O (pdmH2 = 2,6-pyridinedimethanol, Ln = Dy, x = 5 and y = 2.5 for 2 and Ln = Gd, x = 6 and y = 1.5 for 2′), are reported. Two FeIII and two DyIII in 1 formed a zigzag Fe1-Dy1-Dy1a-Fe1a arrangement with a Fe1-Dy1-Dy1a angle of 105.328(3)°. However, in contrast to 1, two CoIII and two DyIII ions in 2 formed a more linear Co1-Dy1-Dy1a-Co1a arrangement with a Co1-Dy1-Dy1a angle of 141.86(2)°. Addnl., two DyIII ions in 1 are eight-coordinated with a triangular dodecahedron geometry, while two DyIII ions in 2 adopt nine-coordination with a muffin geometry. Magnetic studies revealed slow magnetic relaxation behavior for 1, with an energy barrier Ea of 6.9 K. For 2, single mol. magnet behavior was presented under a zero d.c. field with an effective energy barrier Ueff of 64.0(9) K. Ab initio calculations for 1 and 2 indicate that compared to 2, complex 1 has a larger transversal magnetic moment of its ground Kramers doublets (KD) and a larger value of the tunneling parameter (Δt) for the exchanged coupled ground state, which may result in poor single mol. magnet behavior for 1.2,6-Pyridinedimethanol(cas: 1195-59-1HPLC of Formula: 1195-59-1) was used in this study.

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. The basicity and metallophilic high donor number of these π-deficient systems has long favored them as ligands in metal catalysis. The last decade saw pyridine assume a stronger role as functional group for directed C–H oxidation/activation.HPLC of Formula: 1195-59-1

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2022,Ding, Pin; Han, Lingbo; Bai, Jiaxing; Liu, Jingjing; Luan, Xinjun published an article in Science China: Chemistry. The title of the article was 《Fine-tuning hydroxylamines as single-nitrogen sources for Pd(0)-catalyzed diamination of o-bromo(or chloro)-biaryls》.Recommanded Product: 89466-08-0 The author mentioned the following in the article:

An efficient Pd(0)-catalyzed inter-mol. [4+1] annulation of o-bromo(or chloro)-biaryls with bifunctional secondary hydroxylamines for the one-step assembly of synthetically useful carbazoles was reported. Noteworthily, a linchpin for this domino reaction was the judicious selection of both the amino-sources and Pd(0)-catalysts for enabling the prerequisite oxidative addition of aryl halides to Pd(0)-species in the presence of hydroxylamines with a labile N-O bond. In the part of experimental materials, we found many familiar compounds, such as 2-Hydroxyphenylboronic acid(cas: 89466-08-0Recommanded Product: 89466-08-0)

2-Hydroxyphenylboronic acid(cas: 89466-08-0) belongs to acyl phenylboronic acid. Phenylboronic acid (PBA) has been used to extract β-blockers (a class of aminoalcohol-containing drugs) from aqueous solution, rat, and human plasma. Recommanded Product: 89466-08-0

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2022,Valigura, Dusan; Rajnak, Cyril; Titis, Jan; Moncol, Jan; Bienko, Alina; Boca, Roman published an article in Dalton Transactions. The title of the article was 《Unusual slow magnetic relaxation in a mononuclear copper(II) complex》.Related Products of 1195-59-1 The author mentioned the following in the article:

A hexacoordinate Cu(II) complex with the {CuO4O′N} donor set shows an intermol. π-π stacking owing to which a 1D-chain structure is formed. The DC magnetic data at low temperature are consistent with the Curie law. The AC susceptibility shows a field supported slow magnetic relaxation that survives up to 7 K. The relaxation time at T = 2.0 K and BDC = 0.2 T is τ = 0.23 ms and it increases at BDC = 0.6 T to τ = 2.9 ms. In addition to this study using 2,6-Pyridinedimethanol, there are many other studies that have used 2,6-Pyridinedimethanol(cas: 1195-59-1Related Products of 1195-59-1) was used in this study.

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. Related Products of 1195-59-1

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Lagerspets, Emi; Abba, Donatella; Sharratt, Joseph; Eronen, Aleksi; Repo, Timo published an article in 2022. The article was titled 《Water tolerant base free Copper (I) catalyst for the selective aerobic oxidation of primary alcohols》, and you may find the article in Molecular Catalysis.Quality Control of 2,6-Pyridinedimethanol The information in the text is summarized as follows:

Authors report here a base free copper(I) catalyst for the selective aerobic oxidation of primary alcs. to their corresponding aldehydes and various diols to their corresponding lactones or lactols. In the presence of the in situ generated Cu(I)-catalyst with 2,2′-dipyridylamine (dpa) as a ligand and 2,2,6,6-tetramethylpiperdine-N-oxyl (TEMPO) as a persistent radical, the oxidation reaction proceeds under true aerobic conditions, at ambient temperature, utilizing air as the oxidant and without added base. High catalytic activity without over oxidation was achieved for numerous primary alcs. (aliphatic, allylic, benzylic and diols) with different substitution patterns. The catalyst’s stability is unique among reported Cu(I)-catalysts. It is not moisture or air sensitive, and is capable of e.g. oxidizing aliphatic and benzyl alcs. in a water/acetonitrile solution in moderate or in quant. yield (> 99%) in 3 h. In the experiment, the researchers used 2,6-Pyridinedimethanol(cas: 1195-59-1Quality Control of 2,6-Pyridinedimethanol)

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Quality Control of 2,6-Pyridinedimethanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kuranaga, Takefumi; Tamura, Miho; Ikeda, Hiroaki; Terada, Sakahiro; Nakagawa, Yusuke; Kakeya, Hideaki published an article in 2021. The article was titled 《Identification and Total Synthesis of an Unstable Anticancer Macrolide Presaccharothriolide Z Produced by Saccharothrix sp. A1506》, and you may find the article in Organic Letters.Quality Control of 3,5-Dihydroxybenzaldehyde The information in the text is summarized as follows:

Saccharothriolides A-F are 10-membered microbial macrolides proposed to be generated from their precursors presaccharothriolides X-Z. Previously, we isolated presaccharothriolide X, and its unique natural prodrug-like properties have intrigued us. However, the other congeners were not detected. Herein, we detected presaccharothriolide Z using our highly sensitive labeling reagent. Moreover, chem. synthesis of presaccharothriolide Z, the first total synthesis of saccharothriolide-class macrolides, was achieved, and the structure and biol. activity of presaccharothriolide Z were determined In the part of experimental materials, we found many familiar compounds, such as 3,5-Dihydroxybenzaldehyde(cas: 26153-38-8Quality Control of 3,5-Dihydroxybenzaldehyde)

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is a building block. It has been used in the synthesis of 2,4-dimethylbenzoylhydrazones with antileishmanial and antioxidant activities.Quality Control of 3,5-Dihydroxybenzaldehyde

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Lu, Tian-Qi; Wang, Xue-Tao; Cheng, Lan-Tao; Chen, Cheng; Shi, Haiyan; Zheng, Jun; Zheng, Xiu-Ying published an article in 2021. The article was titled 《Soft Metal-Organic Frameworks Based on {Na@Ln6} as a Secondary Building Unit Featuring a Magnetocaloric Effect and Fluorescent Sensing for Cyclohexane and Fe3+》, and you may find the article in Crystal Growth & Design.COA of Formula: C7H9NO2 The information in the text is summarized as follows:

Two series of cluster-based Ln-metal-organic frameworks (MOFs) {[Na@Ln8(EDTA)6(H2O)22]·ClO4·xH2O}n (x ≈ 28, Ln = Gd 1, Ln = Eu 2) and {[Na@Ln9(EDTA)6(H2O)27]·(ClO4)4·xH2O}n (x ≈ 26, Ln = Gd 3, Ln = Eu 4) were prepared by ethylene diamine tetraacetic acid (H4EDTA) to control the hydrolysis of lanthanide ions to form cluster-based secondary building blocks and hydrated metal ions as linkers. Structural anal. showed that all four compounds were formed by using {Na@Ln6} as the node and hydrated [Ln(H2O)5]3+ ion as the linker. Compounds 1-2 and 3-4 featured a two-dimensional (2D) layered structure and a three-dimensional (3D) frame structure, resp. Magnetic studies showed that compounds 1 and 3 displayed a considerable magnetocaloric effect with magnetic entropy values of 32.8 and 33.3 J kg-1 K-1, resp., at low temperature and high field. The magnetic entropy changes of 3 did not increase greatly with the increase of the dimension due to the similar weak magnetic interactions and similar magnetic densities of compounds 1 and 3. Luminescence studies showed that compounds 2 and 4 had a good recognition effect on the cyclohexane mol., and 4 displayed excellent sensitive sensing and a detection effect on Fe3+ ions in MeOH based on the high-sensitivity fluorescence quenching phenomenon. In the experiment, the researchers used many compounds, for example, 2,6-Pyridinedimethanol(cas: 1195-59-1COA of Formula: C7H9NO2)

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridine is a relatively complex molecule and exhibits a number of different bands in IR spectra. Among others, the bands characterizing the ν8a and ν19b modes have been found to be sensitive to the coordination or protonation of the molecule. Note that the band that is diagnostic for the PyH+ ion at about 1545 cm− 1 (ν19b mode) does not overlap with any of the other bands.COA of Formula: C7H9NO2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

The author of 《Redox-responsive ferrocene-containing poly(ionic liquid)s for antibacterial applications》 were Zhang, Tikai; Guo, Jiangna; Ding, Yingying; Mao, Hailei; Yan, Feng. And the article was published in Science China: Chemistry in 2019. Recommanded Product: 3-Bromopropan-1-ol The author mentioned the following in the article:

Ferrocene (Fc)-containing imidazolium type ionic liquids (ILs) and corresponding poly(ionic liquid) (PIL) membranes with tunable antibacterial activity based on electrochem. redox reaction and host-guest chem. were developed. The effect of Fc moiety on the antimicrobial activities against both Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) was studied by min. inhibitory concentration (MIC). The presence of Fc groups highly enhanced the antibacterial efficiency of Fccontaining ILs because of the generation of reactive oxygen species (ROS). The electrochem. oxidation of Fc to Fc+ and the formation of inclusion complexes between Fc and β-CD via host-guest interactions decreased the antibacterial activities of ILs and PIL membranes. The antibacterial activities may be recovered in some extent upon the electrochem. reduction of Fc+ to Fc or the exclusion of the Fc out of the cavity of β-CD. Furthermore, all the Fc-containing PIL membranes showed relatively low hemolysis activities and none cytotoxicity toward human cells, indicating clin. feasibility in topical applications. The experimental part of the paper was very detailed, including the reaction process of 3-Bromopropan-1-ol(cas: 627-18-9Recommanded Product: 3-Bromopropan-1-ol)

3-Bromopropan-1-ol(cas: 627-18-9) was used in the synthesis of fluorescent halide-sensitive quinolinium dyes and molten salt-polymers. Furthermore, it was used in the synthesis of chiral, quaternary prolines via cyclization of quaternary amino acids.Recommanded Product: 3-Bromopropan-1-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts