Tag: 100-200

Related Products of 2240-88-2On March 1, 2021, Woelke, Christian; Diddens, Diddo; Heidrich, Bastian; Winter, Martin; Cekic-Laskovic, Isidora published an article in ChemElectroChem. The article was 《Understanding the Effectiveness of Phospholane Electrolyte Additives in Lithium-Ion Batteries under High-Voltage Conditions》. The article mentions the following:

Six phospholane functional electrolyte additives that enable the formation of an effective cathode electrolyte interphase (CEI) via a polymerization reaction on the electrode surface were designed, synthesized, and comparatively analyzed by means of complementary exptl. and computational methods in order to understand their mode of action in NMC111||graphite battery cells under high voltage conditions. Two reaction mechanisms, namely a phosphate-based and a phosphonate-based mechanism, were postulated and, based on systematic anal., the phosphate mechanism was identified as the more likely. Direct correlation of the phospholane’s structural features and relevant properties impacting the direct correlation of the phospholane’s structural features and relevant properties impacting the overall cycling performance of NMC111||graphite cells, as depicted by capacity retention, stands for a vital example approach towards identifying promising electrolyte components for advanced, targeted applications. In the experiment, the researchers used many compounds, for example, 3,3,3-Trifluoropropan-1-ol(cas: 2240-88-2Related Products of 2240-88-2)

3,3,3-Trifluoropropan-1-ol(cas: 2240-88-2) is a important organic intermediate. It can be used in agrochemical, pharmaceutical and dyestuff field.Related Products of 2240-88-2

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《Introduction of a trinuclear manganese(III) catalyst on the surface of magnetic cellulose as an eco-benign, efficient and reusable novel heterogeneous catalyst for the multi-component synthesis of new derivatives of xanthene》 was written by Ghamari kargar, Pouya; Bagherzade, Ghodsieh; Eshghi, Hossein. Related Products of 873-75-6This research focused ontrinuclear manganese nanocatalyst preparation; xanthene green preparation; aldehyde dimedone three component trinuclear manganese nanocatalyst; carbonyl compound green preparation; alc oxidation trinuclear manganese nanocatalyst. The article conveys some information:

In this work, the new trinuclear manganese catalyst defined as Fe3O4@NFC@NNSM-Mn(III) was successfully manufactured and fully characterized by different techniques, including FT-IR, XRD, TEM, SEM, EDX, VSM, and ICP anal. This magnetic catalysts used for the synthesis of xanthene derivatives I [R = Ph, 4-ClC6H4, 1H-indol-3-yl, etc.; R1 = H, Me]. The critical potential interest in the present method included short reaction time, high yields, recyclability of the catalyst, easy workup and ability to sustain a variety of functional groups, which gave economical as well as ecol. rewards. Also, the synthesized catalyst was used as a recyclable trinuclear catalyst for synthesis of carbonyl compounds via alc. oxidation reactions at 40°C. The magnetic catalyst activity of Fe3O4@NFC@NNSM-Mn(III) could be attributed to the synergistic effects of the catalyst Fe3O4@NFC@NNS-Mn(III) with melamine. Employing a sustainable and safe low temperature, using an eco-friendly solvent, no need to use any additive, and long-term stability and magnetic recyclability of the catalyst for at least six successive runs were the advantages of current protocol toward green chem. This protocol was a benign, environmentally friendly method for heterocycle synthesis. The experimental part of the paper was very detailed, including the reaction process of (4-Bromophenyl)methanol(cas: 873-75-6Related Products of 873-75-6)

(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.Related Products of 873-75-6 It undergoes efficient trimethylsilylation reaction with 1,1,1,3,3,3-hexamethyldisilazane in the presence of catalytic amount of aspartic acid in acetonitrile.

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《Hydroxylation of benzene with hydrogen peroxide by the use of hydrophobic catechols and iron(3+) ion complexes as the catalyst》 was published in Chemistry Letters in 1981. These research results belong to Hotta, Kazuhiko; Tamagaki, Seizo; Suzuki, Yusuke; Tagaki, Waichiro. Synthetic Route of C10H14O2 The article mentions the following:

Hydroxylation of C6H6 with H2O2 was carried out in the presence of 3,4-( HO)2C6H3R (I; R = e.g., Me, Et, H, Bu, hexyl) and Fe3+ in a C6H6-H2O biphase system. The hydrophobic catechols I (R = Bu, hexyl, benzyl, PhCH2CH2) were far more effective as the catalyst than the hydrophilic ones.4-Butylbenzene-1,2-diol(cas: 2525-05-5Synthetic Route of C10H14O2) was used in this study.

4-Butylbenzene-1,2-diol(cas: 2525-05-5) belongs to organoboron compounds. Organoboron compounds are versatile intermediates and as such are some of the most important classes of reagents in modern organic chemistry.Synthetic Route of C10H14O2 Organoboron compounds are less toxic than organostannane reagents, and unlike alkynylzinc and magnesium, many organoboron compounds possess remarkable oxidative and thermal stabilities.

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《Direct Access to 4-Substituted Isoquinolones via a Sequential Pd-Catalyzed Cyclization/Base-Promoted Aromatization/Ring-Opening of N-Propargyl-1,3-oxazolidines》 was written by Xu, Xianjun; Song, Liangliang; Feng, Huangdi; Van der Eycken, Erik V.. Recommanded Product: 157142-48-8 And the article was included in Molecular Catalysis on April 30 ,2022. The article conveys some information:

Herein, a practical Pd-catalyzed cyclization/base-promoted aromatization/ring-opening protocol of N-propargyl-1,3-oxazolidines with carboxylic acids was disclosed. In the current domino reaction, a series of ester-functionalized isoquinolones I [R1 = Ph, 4-MeC6H4, 2-FC6H4, etc.; R2 = H, 6-Me, 7-MeO, etc.; R3 = Ph, 4-MeC6H4, 4-ClC6H4; R4 = Me, t-Bu, Ph, etc.] was obtained in moderate to good yields via C-O bond cleavage, which features a broad functional group tolerance. After reading the article, we found that the author used 2-Amino-2-(4-methylphenyl)ethan-1-ol(cas: 157142-48-8Recommanded Product: 157142-48-8)

2-Amino-2-(4-methylphenyl)ethan-1-ol(cas: 157142-48-8) belongs to anime. Aniline, ethanolamines, and several other amines are major industrial commodities used in making rubber, dyes, pharmaceuticals, and synthetic resins and fibres and for a host of other applications. Most of the numerous methods for the preparation of amines may be broadly divided into two groups: (1) chemical reduction (replacement of oxygen with hydrogen atoms in the molecule) of members of several other classes of organic nitrogen compounds and (2) reactions of ammonia or amines with organic compounds.Recommanded Product: 157142-48-8

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《An organometallic route to chiroptically active ZnO nanocrystals》 was written by Chwojnowska, Elzbieta; Wolska-Pietkiewicz, Malgorzata; Grzonka, Justyna; Lewinski, Janusz. Related Products of 126456-43-7This research focused onzinc oxide nanocrystal chiroptical activity monoanionic aminoalcoholate ligand. The article conveys some information:

The unique optical properties of zinc oxide nanocrystals (ZnO NCs) are strongly dependent on both the properties and the composition of the inorganic core-organic ligand interface. Developing a novel organometallic self-supporting approach, we report on the synthesis and characterization of ZnO nanocrystals coated by chiral monoanionic aminoalcoholate ligands. The resulting ZnO NCs are both chiroptically active and possess size dependent optical properties. The size and in consequence the emission color of the ZnO NCs could be simply adjusted by the characteristic of the aminoalc. used. The experimental part of the paper was very detailed, including the reaction process of (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7Related Products of 126456-43-7)

(1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7) belongs to anime. To avoid the problem of multiple alkylation, methods have been devised for “blocking” substitution so that only one alkyl group is introduced. The Gabriel synthesis is one such method; it utilizes phthalimide, C6H4(CO)2NH, whose one acidic hydrogen atom has been removed upon the addition of a base such as KOH to form a salt.Related Products of 126456-43-7

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On September 1, 2021, Maudhoo, Ashwini; Maharaj, Avinaash; Buonocore, Federica; Martos-Moreno, Gabriel Angel; Argente, Jes煤s; Achermann, John C; Chan, Li F; Metherell, Lou A published an article.COA of Formula: C7H16O2 The title of the article was Missplicing due to a synonymous, T96= exonic substitution in the T-box transcription factor TBX19 resulting in isolated ACTH deficiency.. And the article contained the following:

SUMMARY: Congenital isolated ACTH deficiency (IAD) is a rare condition characterised by low plasma ACTH and serum cortisol with normal production of other pituitary hormones. TBX19 (also known as TPIT) is a T-box pituitary restricted transcription factor important for POMC gene transcription and terminal differentiation of POMC-expressing cells. TBX19 gene mutations have been shown to cause neonatal-onset congenital IAD. We report a neonate of Romanian origin, who presented at 15 h of life with respiratory arrest and hypoglycaemia which recurred over the following 2 weeks. Biochemical investigations revealed IAD, with undetectable serum cortisol (cortisol < 1 渭g/dL; normal range (NR): 7.8-26.2) and plasma ACTH levels within the normal range (22.1 pg/mL; NR: 4.7-48.8). He responded to hydrocortisone treatment. Patient DNA was analysed by a HaloPlex next-generation sequencing array targeting genes for adrenal insufficiency. A novel homozygous synonymous mutation p.Thr96= (Chr1:168260482; c.288G>A; rs376493164; allele frequency 1 脳 10-5, no homozygous) was found in exon 2 of the TBX19 gene. The effect of this was assessed by an in vitro splicing assay, which revealed aberrant splicing of exon 2 giving rise to a mutant mRNA transcript whereas the WT vector spliced exon 2 normally. This was identified as the likely cause of IAD in the patient. The predicted protein product would be non-functional in keeping with the complete loss of cortisol production and early presentation in the patient. LEARNING POINTS: Synonymous variants (a nucleotide change that does not alter protein sequence) usually thought to be benign may still have detrimental effects on RNA and protein function causing disease. Hence, they should not be ignored, especially if very rare in public databases. In vitro splicing assays can be employed to characterise the consequence of intronic and exonic nucleotide gene changes that may alter splicing. Establishing a diagnosis due to a TBX19 mutation is important as it defines a condition of isolated ACTH deficiency not associated with additional pituitary deficiencies. The experimental process involved the reaction of 2-Methyl-2-propylpropane-1,3-diol(cas: 78-26-2).COA of Formula: C7H16O2

2-Methyl-2-propylpropane-1,3-diol(cas:78-26-2) belongs to alcohols. In general, the hydroxyl group makes alcohols polar. Those groups can form hydrogen bonds to one another and to most other compounds. Owing to the presence of the polar OH alcohols are more water-soluble than simple hydrocarbons. COA of Formula: C7H16O2

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On March 29, 1954, Zima, Otto; von Werder, Fritz published a patent.Category: alcohols-buliding-blocks The title of the patent was Choline derivatives. And the patent contained the following:

The compatibility of compounds ROCH2CH2NR12CH2SMe+X- is improved by oxidation of the thio to the sulfoxide group. To a solution of 30 g. dimethyl(尾-hydroxyethyl)(methylthiomethyl)ammonium chloride in 45 cc. water is added 22 g. 30% aqueous H2O2. The yield of dimethyl(尾-hydroxyethyl)(methylsulfinylmethyl)ammonium chloride is 28 g., m. 96掳, also prepared by oxidation of chloromethyl sulfide with H2O2 and condensation with dimethylaminoethanol. In a similar manner is prepared diethyl(尾-hydroxyethyl)(methylsulfinylmethyl)ammonium chloride, m. 126掳. The experimental process involved the reaction of 2-(Methylamino)ethan-1-ol hydrochloride(cas: 62640-03-3).Category: alcohols-buliding-blocks

2-(Methylamino)ethan-1-ol hydrochloride(cas:62640-03-3) belongs to alcohols. In general, the hydroxyl group makes alcohols polar. Those groups can form hydrogen bonds to one another and to most other compounds. Owing to the presence of the polar OH alcohols are more water-soluble than simple hydrocarbons. Category: alcohols-buliding-blocks

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Purt, G. published an article in 1962, the title of the article was The binary system BaO-WO3.Formula: C8H19NO2 And the article contains the following content:

With more than 40 samples of different compositions, the equilibrium diagram BaO-WO3 could be established, m.p. determinations and Debye-Scherrer pictures being used. Two congruently melting compounds appear, leading to 3 eutectics in the system. The experimental process involved the reaction of 2,2′-(tert-Butylazanediyl)diethanol(cas: 2160-93-2).Formula: C8H19NO2

2,2′-(tert-Butylazanediyl)diethanol(cas:2160-93-2) belongs to alcohols. In general, the hydroxyl group makes alcohols polar. Those groups can form hydrogen bonds to one another and to most other compounds. Owing to the presence of the polar OH alcohols are more water-soluble than simple hydrocarbons. Formula: C8H19NO2

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On June 4, 2019, Godlewski, Grzegorz; Cinar, Resat; Coffey, Nathan J.; Liu, Jie; Jourdan, Tony; Mukhopadhyay, Bani; Chedester, Lee; Liu, Ziyi; Osei-Hyiaman, Douglas; Iyer, Malliga R.; Park, Joshua K.; Smith, Roy G.; Iwakura, Hiroshi; Kunos, George published an article.Safety of H-Phg(4-OH)-OH The title of the article was Targeting Peripheral CB1 Receptors Reduces Ethanol Intake via a Gut-Brain Axis. And the article contained the following:

Endocannabinoids acting on the cannabinoid-1 receptor (CB1R) or ghrelin acting on its receptor (GHS-R1A) both promote alc.-seeking behavior, but an interaction between the two signaling systems has not been explored. Here, we report that the peripheral CB1R inverse agonist JD5037 reduces ethanol drinking in wild-type mice but not in mice lacking CB1R, ghrelin peptide or GHS-R1A. JD5037 treatment of alc.-drinking mice inhibits the formation of biol. active octanoyl-ghrelin without affecting its inactive precursor desacyl-ghrelin. In ghrelin-producing stomach cells, JD5037 reduced the level of the substrate octanoyl-carnitine generated from palmitoyl-carnitine by increasing fatty acid 尾-oxidation Blocking gastric vagal afferents abrogated the ability of either CB1R or GHS-R1A blockade to reduce ethanol drinking. We conclude that blocking CB1R in ghrelin-producing cells reduces alc. drinking by inhibiting the formation of active ghrelin and its signaling via gastric vagal afferents. Thus, peripheral CB1R blockade may have therapeutic potential in the treatment of alcoholism. The experimental process involved the reaction of H-Phg(4-OH)-OH(cas: 32462-30-9).Safety of H-Phg(4-OH)-OH

The Article related to behavior role: bsu (biological study, unclassified), biol (biological study), body weight role: bsu (biological study, unclassified), biol (biological study), signal transduction role: bsu (biological study, unclassified), biol (biological study), 尾-oxidation role: bsu (biological study, unclassified), biol (biological study), and other aspects.Safety of H-Phg(4-OH)-OH

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On February 7, 2022, Cao, Yuefeng; Fan, Xiangming published an article.Electric Literature of 78-26-2 The title of the article was Surgical Repair of Secondary Subaortic Stenosis in Congenital Heart Disease Without Initial Subaortic Obstruction.. And the article contained the following:

BACKGROUND: Secondary subaortic stenosis (SSS) is a rare heart disease of the left ventricular outflow tract (LVOT). It usually occurs after cardiovascular correction with or without initial left ventricular outflow tract obstruction (LVOTO). Because most patients with SSS are asymptomatic, many do not realize the need for reoperation until the obstruction worsens. Few studies suggest the characteristics and reasons of SSS without initial SAS. We conducted a retrospective study to describe the characteristics and surgical outcomes of these patients. METHODS: In this study, we examined a single-center retrospective cohort of SSS patients without initial SAS undergoing resection from 2010 to 2019. Patients are defined as secondary subaortic obstruction requiring surgery after cardiovascular correction. Demographics, perioperative findings, and clinical data were analyzed. RESULTS: Twenty-three patients had undergone secondary cardiac surgery for SSS without initial SAS during 10 years in our center. The median age at operation was 7.3 (4.0-13.5) years. In this study, the most commonly associated cardiac lesions were ventricular septal defect (VSD), atrioventricular septal defect (AVSD), patent ductus arteriosus (PDA), and coarctation arch hypoplasia (COA). The surgical techniques included membranous resection of five patients, fibromuscular resection of 17 patients, and reconstruction of the intraventricular baffle of one patient. The results of surgery in these patients are satisfied. The average LVOT gradient at the last follow up was 14.9 (7.8-26.2) mmHg. There was no operative mortality. Two patients had postoperative complications. The median follow-up period was 2.9 (1.1-4.3) years with one late death. Two patients (8.7%) had recurrence of stenosis. CONCLUSIONS: Secondary subaortic stenosis is an uncommon heart disease. The reason is related to several causes, including missed diagnosis, unnoticed abnormalities of LVOT, and further changes of geometric morphology by intracardiac surgery. The results of surgery in these patients are satisfied. However, the recurrence of stenosis is still frequent. The experimental process involved the reaction of 2-Methyl-2-propylpropane-1,3-diol(cas: 78-26-2).Electric Literature of 78-26-2

The Article related to aortic stenosis, subvalvular: complications, aortic stenosis, subvalvular: diagnosis, aortic stenosis, subvalvular: surgery, constriction, pathologic: surgery, heart defects, congenital: complications, heart defects, congenital: diagnosis, heart defects, congenital: surgery, heart septal defects: surgery, humans, infant, reoperation and other aspects.Electric Literature of 78-26-2

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