Tag: 100-200

《Synthesis of N-Aryl- and N-alkyl-Substituted Imidazolium Silver Complexes: Cytotoxic Screening by Using Human Cell Lines Modelling Acute Myeloid Leukaemia》 was written by Alme, Eirin; Toernroos, Karl Wilhelm; Gjertsen, Bjoern Tore; Bjoersvik, Hans-Rene. Recommanded Product: 3-Bromopropan-1-ol And the article was included in ChemMedChem in 2020. The article conveys some information:

A series of N-aryl- and N-alkyl substituted imidazoles has been synthesized and complexed with Ag+ to obtain silver-NHC complexes of the form [Ag(NHC)2]X. These silver-NHC complexes were tested in vitro against the human cell lines HL-60 and MOLM-13, which both model acute myeloid leukemia (AML). A substantial difference in cytotoxicity was revealed varying in the range 13-4 μM and 22-9 μM for HL-60 and MOLM-13, resp. Furthermore, this study revealed that when an alkyl group is installed on the imidazole scaffold, its position substantially influences the cytotoxicity of the corresponding silver NHC complex. In the experiment, the researchers used 3-Bromopropan-1-ol(cas: 627-18-9Recommanded Product: 3-Bromopropan-1-ol)

3-Bromopropan-1-ol(cas: 627-18-9) was used in the synthesis of fluorescent halide-sensitive quinolinium dyes and molten salt-polymers. Furthermore, it was used in the synthesis of chiral, quaternary prolines via cyclization of quaternary amino acids.Recommanded Product: 3-Bromopropan-1-ol

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《Atomically Dispersed Ru on Manganese Oxide Catalyst Boosts Oxidative Cyanation》 was published in ACS Catalysis in 2020. These research results belong to Wang, Hai; Xu, Dongyang; Guan, Erjia; Wang, Liang; Zhang, Jian; Wang, Chengtao; Wang, Sai; Xu, Hua; Meng, Xiangju; Yang, Bo; Gates, Bruce C.; Xiao, Feng-Shou. Computed Properties of C6H7NO The article mentions the following:

There is a strong incentive for environmentally benign and sustainable production of organic nitriles to avoid the use of toxic cyanides. Here we report that manganese oxide nanorod-supported single-site Ru catalysts are active, selective, and stable for oxidative cyanation of various alcs. to give the corresponding nitriles with mol. oxygen and ammonia as the reactants. The very low amount of Ru (0.1 wt %) with at. dispersion boosts the catalytic performance of manganese oxides. Exptl. and theor. results show how the Ru sites enhance the ammonia resistance of the catalyst, bolstering its performance in alc. dehydrogenation and oxygen activation, the key steps in the oxidative cyanation. This investigation demonstrates the high efficiency of a single-site Ru catalyst for nitrile production The experimental process involved the reaction of 3-Pyridinemethanol(cas: 100-55-0Computed Properties of C6H7NO)

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Computed Properties of C6H7NO

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Safety of 4-Butylbenzene-1,2-diolOn November 8, 2016 ,《Sulfo-and carboxybetaine-containing polyampholytes based on poly(2-vinyl pyridine)s: Synthesis and solution behavior》 appeared in Polymer. The author of the article were Billing, Mark; Elter, Johanna K.; Schacher, Felix H.. The article conveys some information:

We present the synthesis and characterization of zwitterionic homopolymers and copolymers based on poly(2-vinyl pyridine) (P2VP). Different molar masses as well as copolymer compositions of poly(styrene-co-2-vinyl pyridine) (P(2VP-co-S)) were synthesized using RAFT (reversible addition fragmentation chain transfer) polymerization, followed by quaternization of the nitrogen atom by either 1,3-propanesultone (P2VPS, P(2VPS-co-S)) or ethyl-2-bromoacetate, followed by ester hydrolysis (P2VPC, P(2VPC-co-S)). The resulting materials were characterized using SEC, 1H and 13C NMR spectroscopy, elemental anal., and zeta potential measurements. Degrees of functionalization ranging from 33 to 76% could be determined and both P2VPC and P2VPS exhibited good solubility over the entire pH-range. Upon incorporation of increasing amounts of styrene, aqueous solubility decreased and also UCST behavior could be observed in case of P(2VP56,S-co-S44). In the experiment, the researchers used many compounds, for example, 4-Butylbenzene-1,2-diol(cas: 2525-05-5Safety of 4-Butylbenzene-1,2-diol)

4-Butylbenzene-1,2-diol(cas: 2525-05-5) belongs to organoboron compounds. Organoboron compounds are versatile intermediates and as such are some of the most important classes of reagents in modern organic chemistry.Safety of 4-Butylbenzene-1,2-diol Organoboron compounds are less toxic than organostannane reagents, and unlike alkynylzinc and magnesium, many organoboron compounds possess remarkable oxidative and thermal stabilities.

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Name: rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraolOn September 30, 2022 ,《Mutual effects of Shewanella putrefaciens-montmorillonite and their impact on uranium immobilization》 was published in Chemosphere. The article was written by Cheng, Wencai; Tang, Huiping; Yi, Yunpeng; Nie, Xiaoqin; Ding, Congcong. The article contains the following contents:

This study investigated the immobilization behavior of U(VI) by the mixture of Shewanella putrefaciens (S. putrefaciens) and montmorillonite with batch experiment The relevant mechanisms were discussed based on the exptl. results and characterizations. It was found that the immobilization of U(VI) by S. putrefaciens-montmorillonite was inhibited at pH < 7.0 and enhanced at pH >7.0. The inhibition effect was due to the aggregation and coverage between S. putrefaciens and montmorillonite, whereas the association of microbial dissolvable organic matters (DOM) on montmorillonite could promote immobilization of U(VI). The evidences of X-photoelectron spectroscopy (XPS) and d. functional theory (DFT) simulation confirmed that the carboxyl-, hydroxyl-, nitrogen-based DOM do have the ability to interacted with U(VI). This work highlights a comprehensive and overlook perspective to understand the immobilization behavior of U(VI) in environmental organo-minerals. After reading the article, we found that the author used rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol(cas: 54-17-1Name: rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol)

rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol(cas: 54-17-1) is the monohydrate form of the alpha isoform of D-glucopyranose, a synthetic simple monosaccharide that is used as an energy source.Name: rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol

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《Inhibition and enhancement of luminol-KIO4-H2O2 chemiluminescence by organic compounds》 was written by Xu, Hong. Electric Literature of C10H14O2 And the article was included in Faguang Xuebao on August 31 ,2006. The article conveys some information:

The inhibition and enhancement of liquid phase CL by organic compounds are of considerable interests in anal. chem. because they can be used for the sensitive detection of numerous compounds The mechanism of inhibition and enhancement is not fully understood and discovery of new enhancers and inhibitors is usually achieved in empirical fashion by trail and error. Although there are reports in literatures concerning the use of luminol-KIO4-H2O2 CL for determination of hydrogen peroxide, glucose and ascorbic acid, the effect of aromatic compounds on luminol-KIO4-H2O2 CL has not been studied systematically. The effects of 36 organic compounds on the luminol-KIO4-H2O2 system chemiluminescence (CL) were studied under different pH conditions of luminol solution The CL signal was detected with flow injection chemiluminescence system (Xi’an Ruimai Electronic Technol. Co.Ltd, China) consisted of model IFFM-D peristaltic pump, mixing tee, model IFFS-A CL detector equipped with glass coil (used as reaction coil and detection cell), photomultiplier, and IBM compatible microcomputer. It was found that most of tested compounds could inhibit or enhance CL intensity. The activities of such inhibitors or enhancers were related to pH value of CL system and number and position of functional groups such as -OH and -NH2 on aromatic ring and property of substituent group, electron delocalization and steric hindrance. The CL spectra and UV-visible absorption spectra were studied and mechanism for CL inhibition and enhancement was also discussed. The mechanism for such inhibition or enhancement of organic compounds is most likely due to the reactions between inhibitors or enhancers and radical intermediates of CL reactions. The possibility of anal. applications was explored based on CL inhibition or enhancement. The results demonstrated that numerous compounds are detectable at ng.mL∓1 level. In addition to this study using 4-Butylbenzene-1,2-diol, there are many other studies that have used 4-Butylbenzene-1,2-diol(cas: 2525-05-5Electric Literature of C10H14O2) was used in this study.

4-Butylbenzene-1,2-diol(cas: 2525-05-5) belongs to organoboron compounds. Organoboron compounds are versatile intermediates and as such are some of the most important classes of reagents in modern organic chemistry. Organoboron compounds are less toxic than organostannane reagents, and unlike alkynylzinc and magnesium, many organoboron compounds possess remarkable oxidative and thermal stabilities. Electric Literature of C10H14O2

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Product Details of 26153-38-8In 2021 ,《Design and synthesis of π-extended resveratrol analogues and in vitro antioxidant and anti-inflammatory activity evaluation》 appeared in Molecules. The author of the article were Nam, Ki Yoon; Damodar, Kongara; Lee, Yeontaek; Park, Lee Seul; Gim, Ji Geun; Park, Jae Phil; Jeon, Seong Ho; Lee, Jeong Tae. The article conveys some information:

The research on resveratrol (1) has been conducted intensively over a long time due to its proven antioxidant activity and disease-fighting capabilities. Many efforts have also been made to increase these biol. effects. In the present study, six new extended aromatic resveratrol analogs containing naphthalene (2) and its bioisosteres quinoline (3 and 4), isoquinoline (5) quinoxaline (6) and quinazoline (7) scaffolds were designed and synthesized using an annulation strategy. The antioxidant and anti-inflammatory activities of these compounds were investigated. All compounds showed better antioxidant activity than resveratrol in ABTS assay. As for the anti-inflammatory test, 5 and 7 exhibited better activity than resveratrol. It is worth noting that nitrogen substitution on the extended aromatic resveratrol analogs has a significant impact on cell viability. Taking the antioxidant activities and NO inhibition activities into consideration, we conclude that isoquinoline analog 5 may qualify for the further investigation of antioxidant and anti-inflammatory therapy. Furthermore, our study results suggest that in order to improve the biol. activity of polyphenolic compounds, extended aromaticity and nitrogen substitution strategy could be a viable method for the design of future drug candidates. In the experimental materials used by the author, we found 3,5-Dihydroxybenzaldehyde(cas: 26153-38-8Product Details of 26153-38-8)

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is a building block. It has been used in the synthesis of 2,4-dimethylbenzoylhydrazones with antileishmanial and antioxidant activities.Product Details of 26153-38-8

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Abuhadba, Sara; Tsuji, Miu; Mani, Tomoyasu; Esipova, Tatiana V. published an article in 2021. The article was titled 《meso-Antracenyl-BODIPY Dyad as a New Photocatalyst in Atom-Transfer Radical Addition Reactions》, and you may find the article in ACS Omega.Application In Synthesis of 5-Hexen-1-ol The information in the text is summarized as follows:

We demonstrate that because of the efficient generation of triplet excited state under UV or visible-light irradiation, meso-antracenyl-BODIPY donor-acceptor dyad can catalyze atom-transfer radical addition (ATRA) reactions between bromomalonate and alkenes. This finding paves the way for the design and application of the new type of heavy atom-free organic chromophores for photocatalysis. The results came from multiple reactions, including the reaction of 5-Hexen-1-ol(cas: 821-41-0Application In Synthesis of 5-Hexen-1-ol)

5-Hexen-1-ol(cas: 821-41-0) is used in cyclization to a tetrahydropyran by phenylselenoetherification. It is also used as a building block in synthetic chemistry.Application In Synthesis of 5-Hexen-1-ol

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Sun, Bin; Zhu, Rui; Zhuang, Xiaohui; Shi, Xiayue; Huang, Panyi; Yan, Zhiyang; Yu, Chuanming; Jin, Can published their research in Organic Letters in 2021. The article was titled 《Visible Light/Tertiary Amine Promoted Synergistic Hydroxydifluoroacetamidation of Unactivated Alkenes under Air》.SDS of cas: 821-41-0 The article contains the following contents:

An efficient and novel method for regioselective hydroxydifluoroacetamidation of alkenes with bromodifluoroacetamides were achieved via a tandem radical pathway mediated by photoredox catalysis under metal-free conditions. This transformation proceeded smoothly in the presence of rhodamine 6G, which afforded a series of α,α-difluoro-γ-hydroxyacetamides in moderate to excellent yields. The significant advantages of this protocol was the low-cost photocatalyst, readily available starting materials, synthetic convenience and wide functional group compatibility. The results came from multiple reactions, including the reaction of 5-Hexen-1-ol(cas: 821-41-0SDS of cas: 821-41-0)

5-Hexen-1-ol(cas: 821-41-0) is a volatile organic compound. Further, it is used to prepare 6-bromo-hex-1-ene by reaction with phosphorus tribromide.SDS of cas: 821-41-0

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《Novel Non-methylene-Interrupted Dienoic and Trienoic Fatty Acids with a Terminal Double Bond in Ovaries of the Limpet Cellana toreuma》 was written by Kawashima, Hideki. HPLC of Formula: 100-55-0 And the article was included in Lipids in 2020. The article conveys some information:

In this study, to obtain further information on the structural diversity of non-methylene-interrupted (NMI) fatty acids (FA) in the gonads of the limpet Cellana toreuma, previously unreported minor NMI FA, fractionated by argentation thin-layer chromatog. (TLC), in the ovaries were characterized by gas chromatog.-mass spectrometry (GC-MS) anal. of their 3-pyridylcarbinol derivatives As a result, five novel NMI FA were identified as 5,14-pentadecadienoic acid (15:2Δ5,14), 5,9,18-nonadecatrienoic acid (19:3Δ5,9,18), 5,9,20-heneicosatrienoic acid (21:3Δ5,9,20), 7,13,20-heneicosatrienoic acid (21:3Δ7,13,20), and 5,9,22-tricosatrienoic acid (23:3Δ5,9,22). Possible biosynthetic pathways for these FA are also discussed in relation to structural variations of NMI FA regioisomers. This study clearly reinforces the findings of our previous works with structurally diverse NMI FA with a terminal double bond. The results came from multiple reactions, including the reaction of 3-Pyridinemethanol(cas: 100-55-0HPLC of Formula: 100-55-0)

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. When pyridine is adsorbed on oxide surfaces or in porous materials, the following species are commonly observed: (i) pyridine coordinated to Lewis acid sites, (ii) pyridine H-bonded to weakly acidic hydroxyls, and (iii) protonated pyridine. At high coverage, physisorbed pyridine and protonated dimers can also be observed.HPLC of Formula: 100-55-0

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《Benchtop NMR for Online Reaction Monitoring of the Biocatalytic Synthesis of Aromatic Amino Alcohols》 was published in ChemCatChem in 2020. These research results belong to Claassen, C.; Mack, K.; Rother, D.. Recommanded Product: 3-Hydroxybenzaldehyde The article mentions the following:

Online analytics provides insights into the progress of an ongoing reaction without the need for extensive sampling and offline anal. In this study, we investigated benchtop NMR as an online reaction monitoring tool for complex enzyme cascade reactions. Online NMR was used to monitor a two-step cascade beginning with an aromatic aldehyde and leading to an aromatic amino alc. as the final product, applying two different enzymes and a variety of co-substrates and intermediates. Benchtop NMR enabled the concentration of the reaction components to be detected in buffered systems in the single-digit mM range without using deuterated solvent. The concentrations determined via NMR were correlated with offline samples analyzed via uHPLC and displayed a good correlation between the two methods. In summary, benchtop NMR proved to be a sensitive, selective and reliable method for online reaction monitoring in (multi-step) biosynthesis. In future, online analytic systems such as the benchtop NMR devices described might not only enable direct monitoring of the reaction, but may also form the basis for self-regulation in biocatalytic reactions. The experimental process involved the reaction of 3-Hydroxybenzaldehyde(cas: 100-83-4Recommanded Product: 3-Hydroxybenzaldehyde)

3-Hydroxybenzaldehyde(cas: 100-83-4) can be used as a reactant along with ethyl acetoacetate and thiourea in the synthesis of corresponding dihydropyrimidine-2-thione (monastrol), using Yb(OTf)3 as a catalyst by Biginelli cyclocondensation reaction.Recommanded Product: 3-Hydroxybenzaldehyde

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