Category: alcohols-buliding-blocks

Ri, Jin Hyok published the artcilePreparation of cement grinding aids based on alumina compounds, Formula: C9H21NO3, the publication is Madencilik (2020), 59(2), 123-129, database is CAplus.

When the cement grinding is performed in the ball mill, the grinding efficiency decreases due to the aggregation of the particles by the electrostatic phenomenon. Therefore, a lot of techniques for preventing agglomeration using various grinding aids have been introduced. In this study, for mineral grinding, the grinding aid composition including a water-soluble aluminate compound and the grinding method in which this grinding aid is used were described. Grinding aids based on aluminate-based compounds not only have high grinding efficiency but are also thermally stable as they are inorganic materials. Compared with the conventional grinding aids based on organic materials such as DEG and TIPA, even if the solid content is half contained, the grinding efficiency is similar and thus the cost can be reduced to half.

Madencilik published new progress about 122-20-3. 122-20-3 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment, name is Triisopropanolamine, and the molecular formula is C9H21NO3, Formula: C9H21NO3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Hu, Peipei published the artcileAssociations between exposure to a mixture of phenols, parabens, and phthalates and sex steroid hormones in children 6-19 years from NHANES, 2013-2016, COA of Formula: C12H10O4S, the publication is Science of the Total Environment (2022), 153548, database is CAplus and MEDLINE.

Humans are typically exposed to mixtures of environmental endocrine-disrupting chems. simultaneously, but most studies have considered only a single chem. or a class of similar chems. We examined the association of exposure to mixtures of 7 chems., including 2 phenols [bisphenol A (BPA) and bisphenol S (BPS)], 2 parabens [methylparaben (MeP) and Pr paraben (PrP)], and 3 phthalate metabolites [Mono-benzyl phthalate (MBzP), mono-iso-Bu phthalate (MiBP), mono (carboxyoctyl) phthalate (MCOP)] with sex steroid hormones. A total of 1179 children aged 6-19 years who had complete data on both 7 chems. and sex steroid hormones of estradiol (E2), total testosterone (TT), and sex hormone-binding globulin (SHBG) were analyzed from the U. S. National Health and Nutrition Examination Survey 2013-2016. Free androgen index (FAI) calculated by TT/SHBG, and the ratio of TT to E2 (TT/E2) were also estimated Puberty was defined if TT ≥ 50 ng/dL in boys, E2 ≥ 20 pg/mL in girls; otherwise prepuberty was defined. Linear regression, weighted quantile sum (WQS) regression, and Bayesian kernel machine regression (BKMR) were performed to estimate the associations of individual chem. or chem. mixtures with sex hormones. The linear regression showed that 2 phenols, 2 parabens, and 3 phthalate metabolites were generally neg. associated with E2, TT, FAI, and TT/E2, while pos. with SHBG. Moreover, these associations were more pronounced among pubertal than prepubertal children. The aforementioned associations were confirmed when further applying WQS and BKMR, and the 3 phthalates metabolites were identified to be the most heavily weighing chems. Exposure to phenols, parabens, and phthalates, either individuals or as a mixture, was neg. associated with E2, TT, FAI and TT/E2, while pos. with SHBG. Those associations were stronger among pubertal children.

Science of the Total Environment published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C12H10O4S, COA of Formula: C12H10O4S.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Chang, Jun Jie published the artcileSynthesis of vinyl iodide chain-end polymers via organocatalyzed chain-end transformation, Recommanded Product: 2-Phenylethanethiol, the publication is Chemical Communications (Cambridge, United Kingdom) (2021), 57(9), 1105-1108, database is CAplus and MEDLINE.

In the presence of alkynes (CH=C-R²), iodide chain-end polymers (Polymer-I) were successfully transformed to vinyl iodide chain-end polymers (polymer-CH=CR²-I) in a single step via organocatalysis. This reaction is completely metal-free and easy to carry out without using special reagents or special conditions. The polymers encompassing polyacrylates and polymethacrylate, and addnl. functionalities (e.g., OH and CF₃) were also incorporated into the R² moiety. The obtained Polymer-CH=CR²-I further served as a useful precursor for copper-catalyzed cross-coupling reactions with various thiols (R³-SH) to yield vinyl sulfide chain-end polymers (polymer-CH=CR²-SR³) with various R³ moieties. Interestingly, under selected conditions, this organocatalysis also offered block-like copolymers containing a conjugated oligo-alkyne segment and a non-conjugated polyacrylate segment. Exploiting the unique structure, the block-like copolymer was used as an efficient dispersant of carbon nanotubes.

Chemical Communications (Cambridge, United Kingdom) published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Recommanded Product: 2-Phenylethanethiol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Feng, Qiangqiang published the artcileModeling on interaction of different strains in 2-KGA mixed culture fermentation, Category: alcohols-buliding-blocks, the publication is Huagong Xuebao (Chinese Edition) (2013), 64(7), 2520-2525, database is CAplus.

The interaction between Bacillus megaterium and Ketogulonicigenium vulgare was studied for 2-keto-L-gulonic acid (2-KGA) mixed culture fermentation Bacillus megaterium might adjust its growth behavior by quorum sensing. Metabolites and autolysis substances of Bacillus megaterium were beneficial to overcoming the metabolic defects of Ketogulonicigenium vulgare and therefore accelerating the latter growth. Ketogulonicigenium vulgare released lysozyme to promote Bacillus megaterium autolysis. Bacillus megaterium autolysis released specific protease substances to enhance sorbitol dehydrogenase (SDH) which might increase the synthesis rate of 2-KGA. Based on such mechanisms, a kinetic model of 2-KGA mixed fermentation was established. Model validation was carried out with four sets of exptl. data under different cultivation conditions. The results demonstrated that the proposed model was able to well describe the growth of two bacteria and 2-KGA production

Huagong Xuebao (Chinese Edition) published new progress about 526-98-7. 526-98-7 belongs to alcohols-buliding-blocks, auxiliary class Sugar Units,Other Sugar Units, name is (3S,4R,5S)-3,4,5,6-Tetrahydroxy-2-oxohexanoic acid, and the molecular formula is C6H10O7, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Hanaya, Kengo published the artcileNickel(II)-Mediated C-S Cross-Coupling Between Thiols and ortho-Substituted Arylboronic Acid, Quality Control of 4410-99-5, the publication is Asian Journal of Organic Chemistry (2021), 10(3), 582-587, database is CAplus.

Herein, a C-S cross-coupling reaction between alkyl thiols or aryl thiols and ortho-substituted arylboronic acids that proceeded in the presence of an inexpensive and ligand-free NiCl₂.6H₂O salt and N-methylmorpholine, a weak base, at 25°C in air were reported. The presence of coordinating and electron-withdrawing groups at the ortho-position of the arylboronic acids played a crucial role in determining the efficiency of the reaction. X-ray crystallog. anal. revealed that the [NiCl₂(DMF)₂(H₂O)₂] complex was formed in-situ. The complex was an excellent precursor of the active nickel species. The reaction offered an extremely mild and operationally convenient method to access a wide variety of alkyl aryl sulfides and diaryl sulfides without using expensive transition metals such as palladium, gold, and rhodium and specialized and expensive ligands.

Asian Journal of Organic Chemistry published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Quality Control of 4410-99-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Koremura, Mitsunobu published the artcileRelation between chemical structure and antimicrobial and insecticidal activities in organonitro compounds. I. Nitroalcohol derivatives, Related Products of alcohols-buliding-blocks, the publication is Takamine Kenkyusho Nenpo (1961), 198-204, database is CAplus.

Compounds (23) including nitroparaffins, nitroalkyl alcs., dinitroparaffins, nitro Ph alcs., ω-nitroacetophenone, and diphenylnitroethane were synthesized and tested for their biol. activities. Most of the alkyl nitro compounds except dinitroparaffins were inactive against plant pathogens and insects, whereas among the α-phenyl-β-nitro alcs. tested, 1-phenyl-2-nitroethanol had high antimicrobial activities against plant pathogens such as Xanthomonas oryzae and Glomerella cingulata and had insecticidal activity against housefly. This tendency applied similarly to the ω-nitro-acetophenone derivatives, where insecticidal activity was lost. The biol. activities of Ph nitro compounds were very low except 1-phenyl-2-nitroethanol, which indicated a possible effect of the partition coefficient of the compound between H₂O and lipid on the biol. activity. It was presumed that the presence of the Ph radical was necessary for antimicrobial and insecticidal activities of the β-nitro compounds

Takamine Kenkyusho Nenpo published new progress about 528594-30-1. 528594-30-1 belongs to alcohols-buliding-blocks, auxiliary class Nitro Compound,Benzene,Phenol,Ether, name is 2-Methoxy-4-(2-nitroethyl)phenol, and the molecular formula is C9H11NO4, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Izumi, Masayuki published the artcileMannose-BSA Conjugates: Comparison Between Commercially Available Linkers in Reactivity and Bioactivity, Formula: C18H20N2O12, the publication is Journal of Carbohydrate Chemistry (2003), 22(5), 317-329, database is CAplus.

Mannosyl ethanolamine and BSA were conjugated together by their amino groups with various homobifunctional cross-linker reagents: disuccinimidyl carbonate (DSC), disuccinimidyl glutarate (DSG), disuccinimidyl suberate (DSS), ethylene glycolbis(succinimidyl-succinate) (EGS), 1,5-difluoro-2,4-dinitrobenzene (DFDNB), di-Et squarate (DES), and thiophosgene (TP). The resulting mannose-BSA conjugates were subjected to an enzyme-linked lectin assay (ELLA)to investigate their affinity to Con A (ConA). With these results, the seven linkers were evaluated on the basis of five criteria, i.e., cost, reactivity, sugar loading, homogeneity, and affinity to ConA. Thus, DSS, DFDNB, and DES seemed to have advantages over the other crosslinking reagents.

Journal of Carbohydrate Chemistry published new progress about 70539-42-3. 70539-42-3 belongs to alcohols-buliding-blocks, auxiliary class pyrrolidine,Ester,Amide,Inhibitor,Inhibitor, name is Bis(2,5-dioxopyrrolidin-1-yl) O,O’-ethane-1,2-diyl disuccinate, and the molecular formula is C18H20N2O12, Formula: C18H20N2O12.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Montero Bastidas, Jose R. published the artcilePara-Selective, Iridium-Catalyzed C-H Borylations of Sulfated Phenols, Benzyl Alcohols, and Anilines Directed by Ion-Pair Electrostatic Interactions, Quality Control of 1400755-06-7, the publication is Journal of the American Chemical Society (2019), 141(39), 15483-15487, database is CAplus and MEDLINE.

Para C-H borylations (CHB) of tetraalkylammonium sulfates [R₄N][ArOSO₃] (R = n-Pr, Bu) and sulfamates [Bu₄N][ArNHSO₃] have been achieved using bipyridine-ligated Ir boryl catalysts, 4,4′-R₂bpy/[Ir(cod)(OMe)]₂/B₂pin₂, yielding borylated phenols 4-(pinB)-RC₆H₃OH (R = halo, Me, CN, CF₃, CF₃O, OMe), together with minor amounts of meta-isomers. Selectivities can be modulated by both the length of the alkyl groups in the tetraalkylammonium cations and the substituents on the bipyridine ligands. Ion pairing, where the alkyl groups of the cation shield the meta C-H bonds in the counteranions, is proposed to account for para selectivity. The 4,4′-dimethoxy-2,2′-bipyridine ligand gave superior selectivities.

Journal of the American Chemical Society published new progress about 1400755-06-7. 1400755-06-7 belongs to alcohols-buliding-blocks, auxiliary class Fluoride,Boronic acid and ester,Benzene,Alcohol,Boronic Acids,Boronate Esters, name is (3-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanol, and the molecular formula is C13H18BFO3, Quality Control of 1400755-06-7.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Petrotchenko, Evgeniy V. published the artcileIsotopically coded cleavable cross-linker for studying protein-protein interaction and protein complexes, SDS of cas: 70539-42-3, the publication is Molecular and Cellular Proteomics (2005), 4(8), 1167-1179, database is CAplus and MEDLINE.

An emerging approach for studying protein-protein interaction in complexes is the combination of chem. crosslinking and mass spectrometric anal. of the cross-linked peptides (cross-links) obtained after proteolysis of the complex. This approach, however, has several challenges and limitations, including the difficulty of detecting the cross-links, the potential interference from noninformative “cross-linked peptides” (dead end and intrapeptide cross-links), and unambiguous identification of the cross-links by mass spectrometry. Thus, the authors have synthesized an isotopically coded ethylene glycol bis(succinimidylsuccinate) derivate (D₁₂-EGS), which contains 12 deuterium atoms for easy detection of cross-links when applied in a 1:1 mixture with its H₁₂ counterpart and is also cleavable for releasing the cross-linked peptides allowing unambiguous identification by MS sequencing. Moreover, hydrolytic cleavage permits rapid distinguishing between different types of cross-links. Cleavage of a dead end cross-link produces a doublet with peaks 4.03 Da apart, with the lower peak appearing at a mol. mass 162 Da lower than the mass of the H₁₂ form of the original cross-linked peptide. Cleavage of an intrapeptide cross-link leads to a doublet 8.05 Da apart and 62 Da lower than the mol. mass of the H₁₂ form of the original cross-linked peptide. Cleavage of an interpeptide cross-link forms a pair of 4.03-Da doublets, with the lower mass member of each pair each shifted up from its unmodified mol. weight by 82 Da because of the attached portion of the cross-linker. All of this information has been incorporated into a software algorithm allowing automatic screening and detection of cross-links and cross-link types in matrix-assisted laser desorption/ionization mass spectra. In summary, the ease of detection of these species through the use of an isotopically coded cleavable cross-linker and the authors’ software algorithm, followed by mass spectrometric sequencing of the cross-linked peptides after cleavage, has been shown to be a powerful tool for studies of multi-component protein complexes.

Molecular and Cellular Proteomics published new progress about 70539-42-3. 70539-42-3 belongs to alcohols-buliding-blocks, auxiliary class pyrrolidine,Ester,Amide,Inhibitor,Inhibitor, name is Bis(2,5-dioxopyrrolidin-1-yl) O,O’-ethane-1,2-diyl disuccinate, and the molecular formula is C18H20N2O12, SDS of cas: 70539-42-3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Huang, Jin published the artcileSimple Approach to Macrocyclic Carbonates with Fast Polymerization Rates and Their Polymer-to-Monomer Regeneration, HPLC of Formula: 111-29-5, the publication is Macromolecules (Washington, DC, United States) (2022), 55(2), 608-614, database is CAplus.

Designing polymeric materials for closed-loop material streams is the key to achieving a circular society. Here, a library of macrocyclic carbonates (MCs) was designed by a facile and direct one-pot, two-step synthesis approach without the use of a solvent at a 10 g scale. We demonstrate that anionic polymerization with tert-butoxide enables the ultrafast ring-opening polymerization (ROP) of MCs with high conversion (>97%) within seconds (3-10 s) at ambient temperature The polymerization rate depends on the odd or even number of methylene groups between the carbonate linkages in the MCs, and not the overall ring size, yielding an “odd-even” effect. This polymerization rate is related to the difference in mol. conformation of the MCs, as determined by X-ray crystallog. The polymers (polypenta-, hexa-, heptamethylene carbonate) were subsequently regenerated back to their original MCs at a high selectivity (95-99 mol %) and good yields (70-85%), hence taking a step toward closing the loop on these long alkyl chain polycarbonates.

Macromolecules (Washington, DC, United States) published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C5H12O2, HPLC of Formula: 111-29-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts