Category: alcohols-buliding-blocks

Bolis, Serena published the artcileUltrafast study of inter- and intrachain energy transfer in a core-polymer, Formula: C20H28B2O4S2, the publication is Journal of Polymer Science, Part B: Polymer Physics (2018), 56(13), 965-969, database is CAplus.

Interchain interactions can play a pos. role in reaching amplified spontaneous emission in an interesting core-polymer system where the donor (side chains) and the acceptor (core) are chem. linked together. Different degree of interchain interactions modifies the photophys. characteristics of the polymer. By means of transient absorption spectroscopy we show that the stimulated emission from the core decreases passing from solid state to concentrated solution and it is almost absent in the diluted solution The conformational rearrangements of the core-polymer chain in solution limits the efficiency of the intrachain Foerster energy transfer mechanism. The free chain rotations decrease the exciton hopping along the conjugated chains, the ratio between donor and acceptor moieties in the polymer, and change the relative orientation of the transition dipoles of the donor and acceptor causing a strong decrease of energy transfer efficiency and subsequently of the gain. © 2018 Wiley Periodicals, Inc. J. Polym. Sci., Part B: Polym. Phys. 2018.

Journal of Polymer Science, Part B: Polymer Physics published new progress about 239075-02-6. 239075-02-6 belongs to alcohols-buliding-blocks, auxiliary class Thiophene,Boronic acid and ester,Boronate Esters, name is 5,5′-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,2′-bithiophene, and the molecular formula is C20H28B2O4S2, Formula: C20H28B2O4S2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Bolis, Serena published the artcileA core copolymer approach to improve the gain properties of a red-emitting molecule, Application of 5,5′-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,2′-bithiophene, the publication is Chemical Communications (Cambridge, United Kingdom) (2013), 49(100), 11761-11763, database is CAplus and MEDLINE.

The authors report a new approach to improve the gain characteristics of a red-emitting based mol. The insertion of the active dye between two polymeric arms prevents the inter-mol. interactions deleterious for the gain. By the ultra-fast pump-probe technique the authors found an efficient energy transfer between the polymer and dye. High gain in the nanosecond timescale regime was proved.

Chemical Communications (Cambridge, United Kingdom) published new progress about 239075-02-6. 239075-02-6 belongs to alcohols-buliding-blocks, auxiliary class Thiophene,Boronic acid and ester,Boronate Esters, name is 5,5′-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,2′-bithiophene, and the molecular formula is C20H28B2O4S2, Application of 5,5′-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,2′-bithiophene.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Ricciardi, Maria published the artcileGlycidol, a Valuable Substrate for the Synthesis of Monoalkyl Glyceryl Ethers: A Simplified Life Cycle Approach, Related Products of alcohols-buliding-blocks, the publication is ChemSusChem (2017), 10(10), 2291-2300, database is CAplus and MEDLINE.

The disposal of any waste by recovering it within the production plant represents the ultimate goal of every biorefinery. In this scenario, the selective preparation of monoalkyl glyceryl ethers (MAGEs) starting from glycidol, obtained as byproduct in the epichlorohydrin production plant, represents a very promising strategy. Here, we report the synthesis of MAGEs through the reaction of glycidol with alcs. catalyzed by a green homogeneous Lewis acids catalyst, such as Bi^III triflate, under very mild reaction conditions. To evaluate the green potential of the proposed alternative, a simplified life cycle assessment (LCA) approach was followed by comparing the environmental performance of the proposed innovative route to prepare MAGEs with that of the most investigated pathway from glycerol. A considerable reduction of all impact categories considered was observed in our exptl. conditions, suggesting that the glycidol-to-MAGEs route can be a valuable integration to the glycerol-to-MAGEs chain. Thanks to the use of primary data within the LCA model, the results achieved are a very good approximation of the real case.

ChemSusChem published new progress about 57044-25-4. 57044-25-4 belongs to alcohols-buliding-blocks, auxiliary class Epoxides,Chiral,Aliphatic hydrocarbon chain,Alcohol, name is (R)-Oxiran-2-ylmethanol, and the molecular formula is C3H6O2, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Ricciardi, Maria published the artcileFirst Attempt of Glycidol-to-Monoalkyl Glyceryl Ethers Conversion by Acid Heterogeneous Catalysis: Synthesis and Simplified Sustainability Assessment, Name: 3-((2-Ethylhexyl)oxy)propane-1,2-diol, the publication is ChemSusChem (2018), 11(11), 1829-1837, database is CAplus and MEDLINE.

The selective preparation of monoalkylglyceryl ethers (MAGEs) is a task for researchers owing to their broad range of applications. In this work, green feedstocks such as glycidol and alcs. were used to prepare MAGEs under mild reaction conditions (80 °C, 3 h, 0.5 mol % catalyst) in the presence of acid heterogeneous catalysts. Nafion shows the best performances in terms of conversion and selectivity to MAGES and also high stability. A comparison of the environmental performances with the most consolidated pathway from glycerol has shown that the usage of glycidol (recovered as a value-added product from Epicerol process) and Nafion leads to a lower impact on ecosystems. In addition, results achieved from a simplified socio-economic anal. show that the innovative route here proposed has potential (at the laboratory scale) of enhancing potential gains and of reducing the social implications resulting from externalities associated with environmental impacts (e.g., CO₂ equivalents).

ChemSusChem published new progress about 70445-33-9. 70445-33-9 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is 3-((2-Ethylhexyl)oxy)propane-1,2-diol, and the molecular formula is C11H24O3, Name: 3-((2-Ethylhexyl)oxy)propane-1,2-diol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Lyle, Steven J. published the artcileMultistep Solid-State Organic Synthesis of Carbamate-Linked Covalent Organic Frameworks, COA of Formula: C6H13BO3, the publication is Journal of the American Chemical Society (2019), 141(28), 11253-11258, database is CAplus and MEDLINE.

Herein, we demonstrate the first example of a multi-step solid-state organic synthesis, in which a new imine-linked two-dimensional covalent organic framework (COF-170, 1) was transformed through three consecutive postsynthetic modifications into porous, crystalline cyclic carbamate and thiocarbamate-linked frameworks. These linkages are previously unreported and inaccessible through de novo synthesis. While not altering the overall connectivity of the framework, these chem. transformations induce significant conformational and structural changes at each step, highlighting the key importance of noncovalent interactions and conformational flexibility to COF crystallinity and porosity. These transformations were assessed using ¹⁵N multi-CP-MAS NMR spectroscopy, providing the first quantitation of yields in COF postsynthetic modification reactions, as well as of amine defect sites in imine-linked COFs. This multi-step COF linkage postsynthetic modification represents a significant step toward bringing the precision of organic solution-phase synthesis to extended solid-state compounds

Journal of the American Chemical Society published new progress about 25240-59-9. 25240-59-9 belongs to alcohols-buliding-blocks, auxiliary class Boronic acid and ester,Boronic Acids,Boronate Esters, name is 4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-ol, and the molecular formula is C6H13BO3, COA of Formula: C6H13BO3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Chamorro-Arenas, Delfino published the artcileSelective, Catalytic, and Dual C(sp³)-H Oxidation of Piperazines and Morpholines under Transition-Metal-Free Conditions, Application In Synthesis of 622-40-2, the publication is Journal of Organic Chemistry (2018), 83(24), 15333-15346, database is CAplus and MEDLINE.

By using cheap and innocuous reagents, such as NaClO₂, NaOCl, and catalytic amounts of TEMPO, a new environmentally friendly protocol for the selective and catalytic TEMPO C(sp³)-H oxidation of piperazines and morpholines to 2,3-diketopiperazines (2,3-DKP) and 3-morpholinones (3-MPs), resp., has been developed. This novel direct access to 2,3-DKP from piperazines provides significant advantages over the traditional N-monoacylation/intramol. C-N cyclization procedure. Addnl., by modulating the amounts of TEMPO, 2-alkoxyamino-3-morpholinone can be prepared from morpholine derivatives, which would enable further functionalization at the C2 position of the morpholine skeleton.

Journal of Organic Chemistry published new progress about 622-40-2. 622-40-2 belongs to alcohols-buliding-blocks, auxiliary class Morpholine,Alcohol, name is 2-Morpholinoethanol, and the molecular formula is C6H13NO2, Application In Synthesis of 622-40-2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Patil, Ujwal S. published the artcileCleavable ester-linked magnetic nanoparticles for labeling of solvent-exposed primary amine groups of peptides/proteins, Quality Control of 70539-42-3, the publication is Analytical Biochemistry (2015), 18-20, database is CAplus and MEDLINE.

To study the solvent-exposed lysine residues of peptides/proteins, we previously reported disulfide-linked N-hydroxysuccinimide ester-modified silica-coated iron oxide magnetic nanoparticles (NHS-SS-SiO₂@Fe₃O₄ MNPs). The presence of a disulfide bond in the linker limits the use of disulfide reducing agent during protein digestion and allows unwanted disulfide formation between the MNPs and protein. In the current work, the disulfide bond was replaced with a cleavable ester group to synthesize NHS ester-modified SiO₂@Fe₃O₄ MNPs. Use of the cleavable ester group provides an improved method for protein labeling and allows the use of disulfide reducing agents during protein digestion.

Analytical Biochemistry published new progress about 70539-42-3. 70539-42-3 belongs to alcohols-buliding-blocks, auxiliary class pyrrolidine,Ester,Amide,Inhibitor,Inhibitor, name is Bis(2,5-dioxopyrrolidin-1-yl) O,O’-ethane-1,2-diyl disuccinate, and the molecular formula is C18H20N2O12, Quality Control of 70539-42-3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Eitzinger, Andreas published the artcileEnantioselective Bifunctional Ammonium Salt-Catalyzed Syntheses of 3-CF₃S-, 3-RS-, and 3-F-Substituted Isoindolinones, COA of Formula: C8H10S, the publication is Advanced Synthesis & Catalysis (2021), 363(7), 1955-1962, database is CAplus and MEDLINE.

Herein, ammonium salt-catalyzed synthesis of chiral 3,3-disubstituted isoindolinones, e.g., I bearing a heteroatom functionality in the 3-position was reported. A broad variety of differently substituted CF₃S- and RS-derivatives were obtained with often high enantioselectivities when using Maruoka’s bifunctional chiral ammonium salt catalyst. In addition, a first proof-of-concept for the racemic synthesis of the analogous F-containing products was obtained as well, giving access to one of the rare examples of a fairly stable α-F-α-amino acid derivative

Advanced Synthesis & Catalysis published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, COA of Formula: C8H10S.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Shiraki, Tadashi published the artcileMass treatment of trichuriasis with several anthelmintics, especially on the statistical criteria for the evaluation of egg-diminishing effects of the drug, Product Details of C28H29NO4, the publication is Acta Medica et Biologica (Niigata, Japan) (1973), 21(1), 11-27, database is CAplus.

A single oral dose of paromomycin sulfate [1263-89-4] (3g), tetrachlorethylene [127-18-4] (1.5 g), bithional [97-18-7] (1.5 g), biphenium hydroxynaphthoate [3818-50-6] (1.4 g), 1-bromo-2-naphthol [573-97-7] (4 g), piperazine [110-85-0] (3 g), and a santonin-kainic acid mixture [51990-05-7] (50 mg-5 mg) given to whipworm (Trichuris trichiura) infested school children gave a 60.0, 52.6, 42.9, 42.9, 33.4, 28.6, and 0% decrease, resp., in the number of eggs in stool samples. Tetrachloroethylene and 1-bromo-2-naphthol completely eliminated eggs from, respectively, 26.3 and 16.7% of the children treated.

Acta Medica et Biologica (Niigata, Japan) published new progress about 3818-50-6. 3818-50-6 belongs to alcohols-buliding-blocks, auxiliary class Anti-infection,Antiparasitic, name is N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxy-2-naphthoate, and the molecular formula is C4H4N2O2, Product Details of C28H29NO4.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Heger, Matthias published the artcileBracketing subtle conformational energy differences between self-solvated and stretched trifluoropropanol, Application of 3,3,3-Trifluoropropan-1-ol, the publication is Physical Chemistry Chemical Physics (2015), 17(15), 9899-9909, database is CAplus and MEDLINE.

The intramol. OH···F hydrogen bond in 3,3,3-trifluoropropanol (TFP) exerts a subtle stabilizing effect that, when compared to the non-fluorinated analog, reorders the five distinguishable conformers and widens the gap between the two most stable structures. Here, we combine findings from Raman spectroscopy in supersonic expansions and high-level quantum-chem. calculations to bracket the energy difference between the two most stable TFP structures at 1.7(5) kJ mol^-1. The torsional potential energy surface suggests consecutive backbone and OH torsional motions for the conformer interconversion, which are discussed in the framework of supersonic jet cooling as a function of nozzle temperature The picture of a bistable cold mol. with trans or gauche backbone emerges, in which the OH group controls the energy difference and modulates the high barrier separating the heavy atom frames.

Physical Chemistry Chemical Physics published new progress about 2240-88-2. 2240-88-2 belongs to alcohols-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Aliphatic hydrocarbon chain,Alcohol, name is 3,3,3-Trifluoropropan-1-ol, and the molecular formula is C3H5F3O, Application of 3,3,3-Trifluoropropan-1-ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts