Category: 499-75-2

Propolis extract combined with oregano essential oil applied to lima bean seeds against Sclerotinia sclerotiorum was written by Cibanal, Irene Laura;Fernandez, Leticia Andrea;Rodriguez, Silvana Andrea;Pellegrini, Cecilia Noemi;Gallez, Liliana Maria. And the article was included in European Journal of Plant Pathology in 2022.Recommanded Product: 499-75-2 This article mentions the following:

In this study, propolis extract (EPE) and oregano essential oil (OEO), both natural products with different bioactive compounds, were evaluated in vitro and in vivo against Sclerotinia sclerotiorum. This phytopathogen is important worldwide as it can contaminate seeds and infect seedlings of many species. Antifungal susceptibility assays on culture media revealed that EPE and OEO were highly active against this phytopathogen, both individually and combined. EPE showed a fungistatic dose-dependent effect, acting mainly through diffusion, while OEO completely prevented mycelial growth at very low concentrations, with a combination of vapor and diffusion activity. Interestingly, OEO was more effective than EPE, as their min. inhibitory concentrations were 0.39μl/mL and 5μl/mL, resp. Combinations of EPE and OEO showed, depending on the doses, additive or synergistic antifungal effects. In the in vivo trial, dilutions of EPE and OEO made in sterile distilled water (SDW) were tested through a pathosystem with lima bean seeds and S. sclerotiorum. Seeds soaked in formulations with 40% EPE + 12% OEO + 48% SDW, and 20% EPE + 6% OEO + 74% SDW reduced disease incidence of 40% and 60% resp., significantly decreased severity, with a min. phytotoxic effect. This study strengthens previous work showing the antifungal action of EPE and OEO against S. sclerotiorum, and, as a main goal, highlights their potential for the development of biofungicides to protect lima bean seeds. In the experiment, the researchers used many compounds, for example, 5-Isopropyl-2-methylphenol (cas: 499-75-2Recommanded Product: 499-75-2).

5-Isopropyl-2-methylphenol (cas: 499-75-2) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Recommanded Product: 499-75-2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Acaricidal activity of carvacrol and thymol on acaricide-resistant Rhipicephalus microplus (Acari: Ixodidae) populations and combination with cypermethrin: Is there cross-resistance and synergism? was written by Novato, Tatiane Pinheiro;Milhomem, Marlise Neves;Marchesini, Paula Barroso Cruz;Coutinho, Ana Lucia;Silva, Isabela Santos;de Souza Perinotto, Wendell Marcelo;de Azevedo Prata, Marcia Cristina;Ferreira, Lorena Lopes;Lopes, Welber Daniel Zanetti;Costa-Junior, Livio Martins;de Oliveira Monteiro, Caio Marcio. And the article was included in Veterinary Parasitology in 2022.COA of Formula: C10H14O This article mentions the following:

This study evaluated the acaricidal activity of thymol and carvacrol on Rhipicephalus microplus populations with different resistance profiles and investigated the synergistic effect of combinations of these monoterpenes with cypermethrin. The adult immersion test (AIT) was used to characterize the susceptibility of tick populations (45 field populations) to synthetic acaricides: deltamethrin, amitraz and chlorfenvinphos. The larval packet test (LPT) was used to determine the LC₅₀ values for thymol (25 tick populations) and carvacrol (20 tick populations). The susceptible strain Porto Alegre (POA) was used as a reference for calculating the resistance ratio (RR). Subsequently, larval immersion tests (LIT) were performed with combinations of cypermethrin with thymol or carvacrol to assess a synergistic effect. In the AIT, deltamethrin showed efficacy > 90% in one (2.2%) population tested (mean: 12.1 and 11.1 for populations 1-25 and 26-40, resp.), whereas amitraz and chlorfenvinphos showed efficacy > 90% for two (4.4%) populations (mean: 61.3 and 47.3 for populations 1-25 and 26-40, resp.) and eight (17.7%) populations (mean: 69.7 and 59.7 for populations 1-25 and 26-40, resp.). In the LPT, the LC₅₀ values for thymol and carvacrol varied from 0.67 to 2.12 mg/mL and 0.55-3.21 mg/mL, with an average LC₅₀ for populations of 1.49 and 1.75 mg/mL, resp. For thymol, no resistance was observed in any of the populations, values of RR₅₀ > 1.5. There was no correlation between the LC₅₀ values for thymol and the efficacy of the chem. acaricides tested. Regarding carvacrol, for only one tick population had the value of RR₅₀ > 1.5, indicating an incipient resistance. No correlation was observed between the LC₅₀ values for carvacrol and the efficacy of tested acaricides. The combination of thymol and carvacrol with cypermethrin showed a synergistic effect in the resistant population (Jaguar – thymol 4.19 and carvacrol 3.67), and no synergistic interaction were showed in the susceptible population. Answering the questions we conclude that: 1 – The comparison between the LC₅₀ values for thymol and carvacrol in field populations and the susceptible strain POA suggests the absence of cross-resistance (ticks and terpenes), and the differences between the LC₅₀ values for thymol and carvacrol in the different R. microplus populations are inherent to the characteristics of each population tested; 2 – the combination of thymol or carvacrol with cypermethrin showed a synergistic effect with different activity according to the population of ticks. In the experiment, the researchers used many compounds, for example, 5-Isopropyl-2-methylphenol (cas: 499-75-2COA of Formula: C10H14O).

5-Isopropyl-2-methylphenol (cas: 499-75-2) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.COA of Formula: C10H14O

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Effect of levels and types of organic, biological, and chemical fertilizers on morphological traits, yield, and uptake rate of elements in Satureja mutica was written by Asadollahi, Amaneh;Abbaszadeh, Bohloul;Torkashvand, Ali Mohammadi;Jahromi, Marzieh Ghanbari. And the article was included in Industrial Crops and Products in 2022.Reference of 499-75-2 This article mentions the following:

Satureja species are of great economic and medical importance due to their high content of essential oils and use in food, cosmetics, and pharmaceutical industries. Due to the domestication and introduction of Satureja mutica cultivars, for the first time and the lack of comprehensive research on its cultivation, the need for research on the nutritional needs of this plant and the introduction of suitable fertilizer treatments that can be used by farmers is important. This experiment was carried out in 2018 and 2019 in field conditions using randomized complete blocks with three replications and 21 treatments in the Research Institute of Forests and Rangelands. The results of mean comparisons of fertilizer treatments (mean of two years) showed that the highest plant height, with 88 and 80 cm, was related to cow manure treatments of 30 and 60 tons per ha, resp. The highest flowering shoot yield, with 4427, 4266, and 4113 kg ha^-1, was obtained from N₅₀P₂₅K₂₅ + vermicompost10 and N₅₀P₂₅K₂₅ + cow manure60 and N₅₀P₂₅K₂₅ + cow manure30 treatments in the second year, resp. The lowest yield of the flowering shoot (849 kg ha^-1) belonged to Pseudomonas putida treatment. The highest leaf yield, with 2556 and 2441 kg ha^-1, was obtained from N₂₅P₂₅K₂₅ + vermicompost10 and N₂₅, P₂₅, K₂₅ +cow manure60 treatments, resp. According to the results, the highest nitrogen content, with 2.44 and 2.32 g/100 g, was obtained from the cow manure30 treatment in the first and second year, resp. The maximum nitrogen uptake with 94.43 kg ha^-1 was obtained from N₅₀, P₂₅, K₂₅ + vermicompost10. The lowest nitrogen uptake at 24 kg ha^-1 was related to Pseudomonas putida treatment. The mean comparison of two years showed that the highest essential oil percentage (2.11 g/100 g) and yield (79.27 kg ha^-1) were obtained from the second year compared with the first year. Carvacrol, γ-terpinene, thymol, and p-cymene were the major components in the essential oil. The results showed that the combined treatments of chem. fertilizers with animal manure and vermicompost are suitable treatments to increase the yield of different organs and essential oil yield in field conditions. In the experiment, the researchers used many compounds, for example, 5-Isopropyl-2-methylphenol (cas: 499-75-2Reference of 499-75-2).

5-Isopropyl-2-methylphenol (cas: 499-75-2) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Reference of 499-75-2

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synthesis, Antifungal Activity, and 3D-QASR of Novel 1,2,3,4-Tetrahydroquinoline Derivatives Containing a Pyrimidine Ether Scaffold as Chitin Synthase Inhibitors was written by Zhang, Xiaoming;Yang, Zhaokai;Xu, Huan;Liu, Yuansheng;Yang, Xinling;Sun, Tengda;Lu, Xingxing;Shi, Fasheng;Yang, Qing;Chen, Wei;Duan, Hongxia;Ling, Yun. And the article was included in Journal of Agricultural and Food Chemistry in 2022.Application of 499-75-2 This article mentions the following:

The introduction of active groups of natural products into the framework of pesticide mols. is an effective approach for discovering active lead compounds, and thus has been widely used in the development of new agrochems. In this work, a novel series of 1,2,3,4-tetrahydroquinoline derivatives containing a pyrimidine ether scaffold were designed and synthesized by the active substructure splicing method. The new compounds showed good antifungal activities against several fungi. Especially, compound (I) displayed excellent in vitro activity against Valsa mali and Sclerotinia sclerotiorum with EC₅₀ values of 0.71 and 2.47 μg/mL, resp. I had slightly stronger inhibitory activity (68.08% at 50 μM) against chitin synthase (CHS) than that of polyoxin D (63.84% at 50 μM) and exhibited obvious curative and protective effects on S. sclerotiorumin vivo. Thus, I can be considered as a new candidate fungicide as a chitin synthase inhibitor. An accurate and reliable three-dimensional quant. structure-activity relationship (3D-QSAR) model presented a useful direction for the further excogitation of more highly active fungicides. Mol. docking revealed that the conventional hydrogen bond mainly affected the binding affinity of I with chitin synthase. The present results will provide a guidance to discover potential CHS-based fungicides for plant disease control in agriculture. In the experiment, the researchers used many compounds, for example, 5-Isopropyl-2-methylphenol (cas: 499-75-2Application of 499-75-2).

5-Isopropyl-2-methylphenol (cas: 499-75-2) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Application of 499-75-2

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chemical composition, antibiofilm, cytotoxic, and anti-acetylcholinesterase activities of Myrtus communis L. leaves essential oil was written by Caputo, Lucia;Capozzolo, Francesca;Amato, Giuseppe;De Feo, Vincenzo;Fratianni, Florinda;Vivenzio, Giovanni;Nazzaro, Filomena. And the article was included in BMC Complementary Medicine and Therapies in 2022.COA of Formula: C10H14O This article mentions the following:

The potential of essential oils (EOs) and of their principal constituents for eradication of biofilm and at the same time the research of new potential acetylcholinesterase inhibitors is gaining increasing interest in last years. The aims of this study were to determine the chem. composition and to evaluate the antibacterial, cytotoxic, and anti-acetylcholinesterase properties of Myrtus communis leaves essential oil and its main constituents. Essential oil was obtained by hydrodistillation of M. communis L. leaves and was analyzed by GC and GC-MS. The antimicrobial activity was carried out against both gram-neg. and gram-pos. bacteria. The microdilution method was used to estimate the min. inhibitory concentrations (MICs). Then, the capacity of essential oil and its main constituent to inhibit biofilm growth, with the method of OToole and Kolterand, and the metabolic activity of biofilm cells through the MTT colorimetric method were evaluated at different times. Moreover, was studied the potential cytotoxic activity against SH-SY5Y cell line with MTT assay and the anti-acetylcholinesterase activity using Ellmans assay. Myrtenyl-acetate, 1,8 cineole, α-pinene, and linalool were the main components in the EO. The myrtle EO, at the min. tested dose (0.4 mg/mL), inhibited S. aureus biofilm by 42.1% and was capable of inhibiting the biofilm cell metabolism in all tested strains, except Staphylococcus aureus. Moreover, the EO showed good cytotoxic and anti-acetylcholinesterase activities IC50 of 209.1 and 32.8μg/mL, resp. The results suggest that myrtle EO and its main constituents could be used as possible products that could act against the resistant pathogenic species E. coli, P. aeruginosa, L. monocytogenes and S. aureus, on the other hand, as possible coadjutants in the treatment of neurol. diseases. In the experiment, the researchers used many compounds, for example, 5-Isopropyl-2-methylphenol (cas: 499-75-2COA of Formula: C10H14O).

5-Isopropyl-2-methylphenol (cas: 499-75-2) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.COA of Formula: C10H14O

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Selenium- and Silicon-Mediated Recovery of Satureja (Satureja mutica Fisch. & C. A. Mey.) Chemotypes Subjected to Drought Stress Followed by Rewatering was written by Karimi, Ehsan;Ghasemnezhad, Azim;Ghorbanpour, Mansour. And the article was included in Gesunde Pflanzen in 2022.Application In Synthesis of 5-Isopropyl-2-methylphenol This article mentions the following:

Little is known about the potential role of selenium and silicon post drought in plants, and the physiol. mechanisms involved are yet to be explored. Medicinal plant cultivation in existing crop systems is of great importance for sustainable production of active ingredients. The first step in this process is to grow the plants under natural field conditions. For this purpose, the effects of drought stress (moderate stress: 25 days without irrigation and severe stress: 40 days without irrigation) and rewatering on physiol. traits and photosynthetic pigments of two forest Satureja chemotypes of “carvacrol/thymol/p-cymene” (Darkesh chemotype) and “thymol/p-cymene/carvacrol” (Pono chemotype) were assessed in two sep. experiments under foliar application of two drought protectants: selenium (0, 5, and 20 mg/l) and silicon (0, 1, and 5 mM). The results showed that at least in one experiment, the proline content of Darkesh and Pono increased by 33.48 and 16.76% following water stress, resp. A significant enhancement was observed in proline level only in the Darkesh chemotype by rewatering. In both chemotypes, the sugar content increased (by 11.59 and 27.41%) as water stress increased, resp. On the other hand, by rewatering, a reduction in sugar content was observed only in the Pono chemotype. Ionic leakage increased in both chemotypes during the second experiment Similar to sugar content, rewatering decreased ionic leakage only in the Pono chemotype. No clear separation was found in the response of forest savory chemotypes to foliar selenium and silicon application. However, selenium-treated plants reduced proline accumulation under drought stress. Based on the obtained results, forest savory as a drought-resistance valuable medicinal plant can be introduced into the crop system, especially in regions with low precipitation and scarce water sources. In the experiment, the researchers used many compounds, for example, 5-Isopropyl-2-methylphenol (cas: 499-75-2Application In Synthesis of 5-Isopropyl-2-methylphenol).

5-Isopropyl-2-methylphenol (cas: 499-75-2) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Application In Synthesis of 5-Isopropyl-2-methylphenol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Exposure to Contaminated River Water is Associated with Early Hatching and Dysregulation of Gene Expression in Early Life Stages of the Endangered Copper Redhorse (Moxostoma hubbsi) was written by Marchand, H.;Barst, B. D.;Boulanger, E.;Vachon, N.;Houde, M.;Xia, J.;Liu, P.;Ewald, J. D.;Bayen, S.;Liu, L.;Head, J. A.. And the article was included in Environmental Toxicology and Chemistry in 2022.Recommanded Product: 499-75-2 This article mentions the following:

The copper redhorse (Moxostoma hubbsi) is an endangered fish that spawns exclusively in the Richelieu River (Quebec, Canada). Tributaries of the Richelieu are contaminated with high levels of current-use pesticides, which may impact early-life stage (ELS) copper redhorse and other native fishes. We assessed the effects of exposure to contaminated river water on ELS copper redhorse and river redhorse (Moxostoma carinatum), a related fish that shares the copper redhorse’s spawning grounds and nursery habitat. A riverside flow-through system was used to expose copper and river redhorse embryos (1000 each) to Richelieu River water or laboratory water as a control. Fish were maintained until 14 days posthatch, and water samples were taken daily for chem. anal. Following a heavy rain event, concentrations of two neonicotinoid pesticides, clothianidin and thiamethoxam, exceeded water quality guidelines for aquatic life (20 ng/L). Using nontargeted screening, we tentatively identified an addnl. 24 pharmaceutical and personal care products and 23 pesticides in river water. Effects of river water on ELS fish were observed in both species, but the copper redhorse appeared to be more sensitive. Fish exposed to river water hatched 10.7 (copper redhorse) and 2.4 (river redhorse) cumulative degree days earlier than controls. Copper redhorse survival was significantly lower in river water (73 ± 16%) compared to laboratory water (93 ± 3%), whereas river redhorse survival was similar between treatments (84 ± 6% and 89 ± 4%, resp.). Sequencing of copper redhorse larvae RNA revealed 18 differentially expressed genes (DEGs) following 14 days of exposure to river water. Eight up-regulated DEGs were linked to immune function and injury response, and seven down-regulated DEGs were involved with digestion and nutrient absorption. The present study provided valuable data on the effects of ELS exposure to a real-world mixture of contaminants in two fish species of concern. In the experiment, the researchers used many compounds, for example, 5-Isopropyl-2-methylphenol (cas: 499-75-2Recommanded Product: 499-75-2).

5-Isopropyl-2-methylphenol (cas: 499-75-2) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Recommanded Product: 499-75-2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Corrosion inhibition property and promotion of green basil leaves extract materials on Ti-Zr conversion composite coatings was written by Tian, Yuqin;Zhong, Li;Sheng, Xinxin;Zhang, Xinya. And the article was included in Advanced Composites and Hybrid Materials in 2022.Application In Synthesis of 5-Isopropyl-2-methylphenol This article mentions the following:

In this study, the extract obtained from green plant basil leaves was introduced into a corrosion medium NaCl solution to investigate the corrosion inhibition ability of basil leaves extract (BLE) on aluminum alloy (AA6061). The influence of BLE on the corrosion resistance of Ti-Zr conversion coatings (TiZrCCs) on AA6061 was also investigated. The protective performance of BLE on AA6061 was investigated through SEM (SEM). The TiZrCCs were characterized by SEM, XPS, and electrochem. tests including potentiodynamic polarization curves and electrochem. impedance spectroscopy. The results of SEM show that BLE effectively prevented AA6061 from producing corrosion products during immersion in corrosive media. As for the TiZrCCs, SEM results reveal that BLE helped to form a more complete conversion coating and greatly improved the problem of coating cracks. Compared with the blank conversion coating, the corrosion rate of the coating with the introduction of BLE decreased from 0.043 to 0.007 mpy. In addition, d. functional theory calculation was performed on several main substances in BLE, including methyleugenol, carvacrol, linalool, rosmarinic acid, and eugenol, and the reactivity and reaction sites of each mol. were theor. analyzed. The results indicate that rosmarinic acid has the maximum electronegativity and the min. hardness, as well as the best reactivity. Green plant basil leaves extract materials can effectively promote the coating formation process of titanium-zirconium conversion coatings and enhance the corrosion resistance of the coatings. In the experiment, the researchers used many compounds, for example, 5-Isopropyl-2-methylphenol (cas: 499-75-2Application In Synthesis of 5-Isopropyl-2-methylphenol).

5-Isopropyl-2-methylphenol (cas: 499-75-2) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Application In Synthesis of 5-Isopropyl-2-methylphenol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Development of an N-Terminal BRD4 Bromodomain-Targeted Degrader was written by Divakaran, Anand;Scholtz, Cole R.;Zahid, Huda;Lin, Wenwei;Griffith, Elizabeth C.;Lee, Richard E.;Chen, Taosheng;Harki, Daniel A.;Pomerantz, William C. K.. And the article was included in ACS Medicinal Chemistry Letters in 2022.Synthetic Route of C10H14O This article mentions the following:

Targeted protein degradation is a powerful induced-proximity tool to control cellular protein concentrations using small mols. However, the design of selective degraders remains empirical. Among bromodomain and extra-terminal (BET) family proteins, BRD4 is the primary therapeutic target over family members BRD2/3/T. Existing strategies for selective BRD4 degradation use pan-BET inhibitors optimized for BRD4:E3 ubiquitin ligase (E3) ternary complex formation, but these result in residual inhibition of undegraded BET-bromodomains by the pan-BET ligand, obscuring BRD4-degradation phenotypes. Using our selective inhibitor of the first BRD4 bromodomain, iBRD4-BD1 (I) (IC₅₀ = 12 nM, 23- to 6200-fold intra-BET selectivity), we developed dBRD4-BD1 to selectively degrade BRD4 (DC₅₀ = 280 nM). Notably, dBRD4-BD1 upregulates BRD2/3, a result not observed with degraders using pan-BET ligands. Designing BRD4 selectivity up front enables anal. of BRD4 biol. without wider BET-inhibition and simplifies designing BRD4-selective heterobifunctional mols., such as degraders with new E3 recruiting ligands or for addnl. probes beyond degraders. In the experiment, the researchers used many compounds, for example, 5-Isopropyl-2-methylphenol (cas: 499-75-2Synthetic Route of C10H14O).

5-Isopropyl-2-methylphenol (cas: 499-75-2) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Synthetic Route of C10H14O

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Eugenol and carvacrol attenuate brain D-galactose-induced aging-related oxidative alterations in rats was written by El-Far, Ali H.;Mohamed, Hadeer H.;Elsabagh, Doaa A.;Mohamed, Shymaa A.;Noreldin, Ahmed E.;Al Jaouni, Soad K.;Alsenosy, Abdelwahab A.. And the article was included in Environmental Science and Pollution Research in 2022.Computed Properties of C10H14O This article mentions the following:

Aging represents the accumulation of progressive changes in a human being over time and can cover phys., psychol., and social changes. It is an oxidative stress-associated process that progresses with age. The antioxidant activity of either eugenol (EU) or carvacrol (CAR) for aging in rats induced by D-gal for 42 days was investigated in the current study using 10 and 20 mg of EU/kg/day/orally, while CAR was supplemented by 40 and 80 mg /kg/day/orally. Biochem., mRNA expression, and histopathol. assessments of brain samples evaluated the oxidative alterations induced by D-gal and the protective role of EU and CAR. Results showed that D-gal was causing oxidative alternation of the brain that was recognized via upregulation of p53 and p21 mRNA expression levels, as aging markers and Bax mRNA expression level, as an apoptotic marker. Also, the results observed alterations in the levels of biochem. markers as creatine phosphokinase (CPK) and triacylglycerol (TAG), besides, enhancement of brain antioxidant capacity. Finally, these results compared with the groups treated with EU and CAR to observe that the EU and CAR potentially attenuate these aging-related oxidative alterations in a dose-dependent manner. Finally, we can conclude that EU and CAR supplementations are considered promising natural protective compounds that could delay aging and maintain health. In the experiment, the researchers used many compounds, for example, 5-Isopropyl-2-methylphenol (cas: 499-75-2Computed Properties of C10H14O).

5-Isopropyl-2-methylphenol (cas: 499-75-2) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Computed Properties of C10H14O

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts