4048-33-3 Archives - Page 4 of 9 - Alcohols-buliding-blocks

Hou, Rui’s team published research in Journal of Renewable Materials in 2020 | CAS: 4048-33-3

6-Aminohexan-1-ol(cas: 4048-33-3) can undergo cyclization over copper supported on γ-alumina and magnesia to form hexahydro-1H-azepine. It may be used along with glutaric acid to generate poly(ester amide)s with excellent film- and fiber forming properties.Reference of 6-Aminohexan-1-ol

Reference of 6-Aminohexan-1-olIn 2020 ,《Synthesis and properties of thermoplastic polyisocyanurates:polyisocyanuratoamide, polyisocyanurato(ester-amide) and polyisocyanurato(urea-ester)》 appeared in Journal of Renewable Materials. The author of the article were Hou, Rui; Zhang, Zhihuang; Zhang, Guangzhao; Tang, Donglin. The article conveys some information:

It has been proved that introducing isocyanurate into polymer chains could improve the flame retardancy of polymers. We describe in this work the synthesis and the thermal property study of three thermoplastic polyisocyanurates, which are polyisocyanuratoamide (PICA-6), polyisocyanurato(ester amide) (PICEA-6) and polyisocyanurato(urea ester) (PICUE-6). These polymers show similar and improved thermal stability with the existence of isocyanurate rings. PICA-6 is more crystallizable than the rest two and the melting temperature is found to be around 240°C but it still crystallizes slowly. For PICEA-6 and PICUE-6, only glass transition can be observed on the DSC traces. The glass transition temperature follows the order of PICA-6 > PICEA-6 > PICUE-6 (101.9, 77.9 and 28.7°C, resp.). In the experimental materials used by the author, we found 6-Aminohexan-1-ol(cas: 4048-33-3Reference of 6-Aminohexan-1-ol)

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Alcohol – Wikipedia,
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Swanson, W. Benton’s team published research in RSC Chemical Biology in 2022 | CAS: 4048-33-3

Synthetic Route of C6H15NOIn 2022 ,《A library of Rhodamine6G-based pH-sensitive fluorescent probes with versatile in vivo and in vitro applications》 appeared in RSC Chemical Biology. The author of the article were Swanson, W. Benton; Durdan, Margaret; Eberle, Miranda; Woodbury, Seth; Mauser, Ava; Gregory, Jason; Zhang, Boya; Niemann, David; Herremans, Jacob; Ma, Peter X.; Lahann, Joerg; Weivoda, Megan; Mishina, Yuji; Greineder, Colin F.. The article conveys some information:

Acidic pH is critical to the function of the gastrointestinal system, bone-resorbing osteoclasts, and the endolysosomal compartment of nearly every cell in the body. Non-invasive, real-time fluorescence imaging of acidic microenvironments represents a powerful tool for understanding normal cellular biol., defining mechanisms of disease, and monitoring for therapeutic response. While com. available pH-sensitive fluorescent probes exist, several limitations hinder their widespread use and potential for biol. application. To address this need, we developed a novel library of pH-sensitive probes based on the highly photostable and water-soluble fluorescent mol., Rhodamine 6G. We demonstrate versatility in terms of both pH sensitivity (i.e., pKa) and chem. functionality, allowing conjugation to small mols., proteins, nanoparticles, and regenerative biomaterial scaffold matrixes. Furthermore, we show preserved pH-sensitive fluorescence following a variety of forms of covalent functionalization and demonstrate three potential applications, both in vitro and in vivo, for intracellular and extracellular pH sensing. Finally, we develop a computation approach for predicting the pH sensitivity of R6G derivatives, which could be used to expand our library and generate probes with novel properties. In addition to this study using 6-Aminohexan-1-ol, there are many other studies that have used 6-Aminohexan-1-ol(cas: 4048-33-3Synthetic Route of C6H15NO) was used in this study.

Referemce:
Alcohol – Wikipedia,
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Miyagawa, Atsushi’s team published research in Carbohydrate Polymers in 2020 | CAS: 4048-33-3

Recommanded Product: 4048-33-3In 2020 ,《Synthesis of β-1,3-glucan mimics by β-1,3-glucan trisaccharyl monomer polymerization》 appeared in Carbohydrate Polymers. The author of the article were Miyagawa, Atsushi; Yamamura, Hatsuo. The article conveys some information:

β-1,3-Glucans are important as immunostimulating agents in living organisms. The multivalent binding of β-1,3-glucans to dectin-1, a cell surface receptor, activates immunol. defenses. To study artificial immunostimulating agents, glycopolymers carrying β-1,3-glucan trisaccharides as artificial ligands were synthesized. The β-1,3-glucan trisaccharide, defined as an active unit of β-1,3-glucan, was constructed from D-glucose by glycosylation. A norbornene group was introduced as a polymerizable group into the trisaccharide derivative at the aglycon. The prepared endo/exo norbornene stereoisomers of the monomers were separated by silica gel chromatog. and identified by NMR spectroscopy and mass spectrometry. The synthesized glycosyl monomers were polymerized and copolymerized with norbornene using 2nd generation Hoveyda-Grubbs catalyst, deprotected, and purified by gel filtration to prepare water-soluble glycopolymers of varied compositions and high mol. weights These polymers will have the potential for multivalent binding to dectin-1 to activate immune response and facilitate studies to understand the binding mechanisms of β-1,3-glucans with dectin-1. The results came from multiple reactions, including the reaction of 6-Aminohexan-1-ol(cas: 4048-33-3Recommanded Product: 4048-33-3)

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Alcohol – Wikipedia,
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Lee, Young Woong’s team published research in Macromolecular Research in 2021 | CAS: 4048-33-3

6-Aminohexan-1-ol(cas: 4048-33-3) may be used along with glutaric acid to generate poly(ester amide)s with excellent film- and fiber forming properties. It can undergo cyclization over copper supported on γ-alumina and magnesia to form hexahydro-1H-azepine.Electric Literature of C6H15NO

Lee, Young Woong; Yeop, Jiwoo; Kim, Jin Young; Woo, Han Young published an article in 2021. The article was titled 《Fullerene-Based Photoactive A-D-A Triads for Single-Component Organic Solar Cells: Incorporation of Non-Fused Planar Conjugated Core》, and you may find the article in Macromolecular Research.Electric Literature of C6H15NO The information in the text is summarized as follows:

Two acceptor-donor-acceptor (A-D-A) single-component (SC) photovoltaic triad mols., P3T4Rh-C6-PC61BM and P3T4Rh-C10-PC61BM, were synthesized. A conformation-locked planar conjugated core, 1,4-bis(thiophenylphenylthiophene)-2,5-difluorophenylene (P3T4), with intrachain noncovalent coulombic interactions was coupled with two fullerene derivatives, [6,6]-phenyl-C61 butyric acid propargyl ester, via copper (I)-catalyzed azide-alkyne 1,3-dipolar cycloaddition The D-A separation was varied by modulating the spacer alkyl chain length (C6 and C10). Both SC triads exhibited maximum absorption by the P3T4 core at λabs = 507-510 nm, as well as absorption by PC61BM at ∼300 nm. Because of the broken conjugation between the P3T4 core and PC61BM termini, the HOMO (-5.58 to -5.59 eV) was determined by the P3T4 moiety, and the LUMO (-3.89 to -3.92 eV) was determined by PC61BM in the SC structures. In diluted solution, both SC triads showed significant photoluminescence quenching, indicating efficient intramol. charge transfer between the P3T4 and PC61BM moieties. However, the semicrystalline packing of the P3T4 core was severely disrupted by the incorporation of a bulky PC61BM moiety at each terminus, which degraded the carrier transport and diode characteristics of SC organic solar cells (SCOSCs) based on P3T4Rh-C6-PC61BM and P3T4Rh-C10-PC61BM, as indicated by poor power conversion efficiency (∼0.4%). No clear spacer length effect was observed To improve the performance of SCOSCs, a design strategy is needed that enhances the intermol. packing and ordering of the D and A moieties, which are important prerequisites for the development of optimal SC photoactive mols. The experimental process involved the reaction of 6-Aminohexan-1-ol(cas: 4048-33-3Electric Literature of C6H15NO)

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Alcohol – Wikipedia,
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Lee, Jen-Yu’s team published research in ACS Applied Energy Materials in 2021 | CAS: 4048-33-3

Synthetic Route of C6H15NOIn 2021 ,《Semi-Interpenetrating Polymer Network Electrolytes Based on a Spiro-Twisted Benzoxazine for All-Solid-State Lithium-Ion Batteries》 appeared in ACS Applied Energy Materials. The author of the article were Lee, Jen-Yu; Yu, Tsung-Yu; Chung, Pei-Hsuan; Lee, Wen-Ya; Yeh, Shih-Chieh; Wu, Nae-Lih; Jeng, Ru-Jong. The article conveys some information:

A spiro-twisted benzoxazine, namely, 6,6′-(6,6,6′,6′-tetramethyl-6,6′,7,7′-tetrahydro-2H,2′H-8,8′-spirobi[indeno[5,6-e][1,3]oxazin]-3,3′(4H,4′H)-diyl)bis(hexan-1-ol) (TSBZ6D), was successfully developed as a semi-interpenetrating polymer network (s-IPN) matrix for solid polymer electrolytes (SPEs). The designed spiro-twisted mol. structure of TSBZ6D constitutes an SPE matrix with a high fractional free volume that facilitates the transport of lithium ions. In the meantime, its crosslinking network structure enables a remarkable enhancement in the mech. properties of SPEs. When combined with poly(ethylene oxide) (PEO) electrolytes, the TSBZ6D s-IPN imparts an enhancement of >300 and 1100% in tensile stress and in tensile strain, resp., to the PEO-TSBZ6D (PT) composite SPEs over the PEO/lithium salt sample. Electrochem. testing of sym. Li/PT/Li cells indicates the effectiveness of PT SPEs in mitigating the short-circuiting problem caused by Li dendrite formation. We demonstrated that a specific capacity of 166 mAh g-1 (0.1 C) at 80 °C and a promising cycle stability have been achieved by an all-solid-state LiFePO4/PT/Li. The experimental process involved the reaction of 6-Aminohexan-1-ol(cas: 4048-33-3Synthetic Route of C6H15NO)

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Alcohol – Wikipedia,
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Prakash, Thazha P.’s team published research in Nucleic Acids Research in 2019 | CAS: 4048-33-3

The author of 《Fatty acid conjugation enhances potency of antisense oligonucleotides in muscle》 were Prakash, Thazha P.; Mullick, Adam E.; Lee, Richard G.; Yu, Jinghua; Yeh, Steve T.; Low, Audrey; Chappell, Alfred E.; Oestergaard, Michael E.; Murray, Sue; Gaus, Hans J.; Swayze, Eric E.; Seth, Punit P.. And the article was published in Nucleic Acids Research in 2019. Formula: C6H15NO The author mentioned the following in the article:

Enhancing the functional uptake of antisense oligonucleotide (ASO) in the muscle will be beneficial for developing ASO therapeutics targeting genes expressed in the muscle. We hypothesized that improving albumin binding will facilitate traversal of ASO from the blood compartment to the interstitium of the muscle tissues to enhance ASO functional uptake. We synthesized structurally diverse saturated and unsaturated fatty acid conjugated ASOs with a range of hydrophobicity. The binding affinity of ASO fatty acid conjugates to plasma proteins improved with fatty acid chain length and highest binding affinity was observed with ASO conjugates containing fatty acid chain length from 16 to 22 carbons. The degree of unsaturation or conformation of double bond appears to have no influence on protein binding or activity of ASO fatty acid conjugates. Activity of fatty acid ASO conjugates correlated with the affinity to albumin and the tightest albumin binder exhibited the highest activity improvement in muscle. Palmitic acid conjugation increases ASO plasma Cmax and improved delivery of ASO to interstitial space of mouse muscle. Conjugation of palmitic acid improved potency of DMPK, Cav3, CD36 and Malat-1 ASOs (3- to 7-fold) in mouse muscle. Our approach provides a foundation for developing more effective therapeutic ASOs for muscle disorders. After reading the article, we found that the author used 6-Aminohexan-1-ol(cas: 4048-33-3Formula: C6H15NO)

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Alcohol – Wikipedia,
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Liu, Qun’s team published research in Polymer Degradation and Stability in 2019 | CAS: 4048-33-3

The author of 《Enzymatic degradation of fluorinated Poly(ε-caprolactone) (PCL) block copolymer films with improved hydrophobicity》 were Liu, Qun; Wang, Haipeng; Chen, Lei; Li, Wulong; Zong, Yakun; Sun, Yi; Li, Zhanxiong. And the article was published in Polymer Degradation and Stability in 2019. COA of Formula: C6H15NO The author mentioned the following in the article:

Fluorinated Poly(ε-caprolactone) (PCL) block copolymers PCL-PTFOA(2 h), PCL-PTFOA(4 h), PCL-PTFOA(6 h), PCL-PTFOA(8 h) were prepared via esterification by using poly(1H,1H,2H,2H-perfluorooctylacrylate) (PTFOA) with different mol. weights as reactants. It was found that PCL-PTFOA(6 h) and PCL-PTFOA(8 h) possessed the similar mol. weight via GPC anal. PCL and fluorinated PCL block copolymers films were prepared by solution casting method. The structure and properties of film surface of the fluorinated PCL block copolymers were analyzed by energy dispersive X-ray spectrometer (EDS), scanning electron microscope (SEM), Differential scanning calorimetry (DSC), water contact angles (WCAs) and the surface free energy. The results showed that the fluorinated PCL films possessed improved hydrophobicity because of the microphase separation between fluoropolymer chain and PCL chain. The enzymic degradation of PCL, PCL-PTFOA(2 h), PCL-PTFOA(4 h) and PCL-PTFOA(6 h) films were performed at 37 °C in a phosphate buffer solution (PBS, 0.1 M, with a pH of 7.2-7.4) with lipase and analyzed by weight loss, SEM and EDS. It was found that the introduction of fluorine-containing segment reduced the rate of enzymic degradation of the copolymer film in the early period, while increased the finally weight loss rate with a prolonged time. In addition, the enzymic degradation rate of PCL-PTFOA(2 h) film and PCL-PTFOA(4 h) film was faster than that of PCL-PTFOA(6 h) film. The experimental part of the paper was very detailed, including the reaction process of 6-Aminohexan-1-ol(cas: 4048-33-3COA of Formula: C6H15NO)

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Dou, Shilei’s team published research in Chemistry – A European Journal in 2020 | CAS: 4048-33-3

《Amphiphilic Fluorescence Resonance Energy-Transfer Dyes: Synthesis, Fluorescence, and Aggregation Behavior in Water》 was published in Chemistry – A European Journal in 2020. These research results belong to Dou, Shilei; Wang, Ying; Zhang, Xin. COA of Formula: C6H15NO The article mentions the following:

Amphiphilic pyrene/perylene bis-chromophore dyes were synthesized from unsym. substituted perylene bisimide dyes, which were obtained through three synthetic methods. The optical and aggregation behaviors of these functional dyes were studied by means of UV/Vis absorption and fluorescence spectroscopy, dynamic light scattering, and TEM. These dyes are highly fluorescent and cover the whole visible-light region. A donor/acceptor dye displays intramol. fluorescence resonance energy transfer (FRET), with a high efficiency of up to 96.4% from pyrene to perylene bisimide chromophores, which leads to a high fluorescence color sensitivity to environmental polarity. Under a λ=365 nm UV lamp, the light-emitting colors of the donor/acceptor dye change from green to yellow with increasing solvent polarity, which demonstrates application potential as a new class of FERT probes. The donor/acceptor dye in water was assembled into hollow vesicles with a narrow size distribution. The bilayer structure of the vesicular wall was directly observed by means of TEM. These vesicular aggregates in water are fluorescent at λ=650-850 nm within the near-IR region. In the experimental materials used by the author, we found 6-Aminohexan-1-ol(cas: 4048-33-3COA of Formula: C6H15NO)

Referemce:
Alcohol – Wikipedia,
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Riahinasab, Sheida T.’s team published research in Nature Communications in 2019 | CAS: 4048-33-3

The author of 《Nanoparticle-based hollow microstructures formed by two-stage nematic nucleation and phase separation》 were Riahinasab, Sheida T.; Keshavarz, Amir; Melton, Charles N.; Elbaradei, Ahmed; Warren, Gabrielle I.; Selinger, Robin L. B.; Stokes, Benjamin J.; Hirst, Linda S.. And the article was published in Nature Communications in 2019. Recommanded Product: 4048-33-3 The author mentioned the following in the article:

Rapid bulk assembly of nanoparticles into microstructures is challenging, but highly desirable for applications in controlled release, catalysis, and sensing. We report a method to form hollow microstructures via a two-stage nematic nucleation process, generating size-tunable closed-cell foams, spherical shells, and tubular networks composed of closely packed nanoparticles. Mesogen-modified nanoparticles are dispersed in liquid crystal above the nematic-isotropic transition temperature (TNI). On cooling through TNI, nanoparticles first segregate into shrinking isotropic domains where they locally depress the transition temperature On further cooling, nematic domains nucleate inside the nanoparticle-rich isotropic domains, driving formation of hollow nanoparticle assemblies. Structural differentiation is controlled by nanoparticle d. and cooling rate. Cahn-Hilliard simulations of phase separation in liquid crystal demonstrate qual. that partitioning of nanoparticles into isolated domains is strongly affected by cooling rate, supporting exptl. observations that cooling rate controls aggregate size. Microscopy suggests the number and size of internal voids is controlled by second-stage nucleation. The experimental part of the paper was very detailed, including the reaction process of 6-Aminohexan-1-ol(cas: 4048-33-3Recommanded Product: 4048-33-3)

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ranque, Pierre’s team published research in ACS Applied Energy Materials in 2020 | CAS: 4048-33-3

《Scalable Route to Electroactive and Light Active Perylene Diimide Dye Polymer Binder for Lithium-Ion Batteries》 was written by Ranque, Pierre; George, Chandramohan; Dubey, Rajeev K.; van der Jagt, Remco; Flahaut, Delphine; Dedryvere, Remi; Fehse, Marcus; Kassanos, Panagiotis; Jager, Wolter F.; Sudhoelter, Ernst J. R.; Kelder, Erik M.. Reference of 6-Aminohexan-1-ol And the article was included in ACS Applied Energy Materials in 2020. The article conveys some information:

Developing multifunctional polymeric binders is key to the design of energy storage technologies with value-added features. We report that a multigram-scale synthesis of perylene diimide polymer (PPDI), from a single batch via polymer analogous reaction route, yields high mol. weight polymers with suitable thermal stability and minimized solubility in electrolytes, potentially leading to improved binding affinity toward electrode particles. Further, it develops strategies for designing copolymers with virtually any desired composition via a subsequent grafting, leading to purpose-built binders. PPDI dye as both binder and electroactive additive in lithium half-cells using lithium iron phosphate exhibits good electrochem. performance. In the experiment, the researchers used 6-Aminohexan-1-ol(cas: 4048-33-3Reference of 6-Aminohexan-1-ol)

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts