Category: 1611-56-9

Related Products of 1611-56-9, Redox catalysis has been broadly utilized in electrochemical synthesis due to its kinetic advantages over direct electrolysis. The appropriate choice of redox mediator can avoid electrode passivation and overpotential. 1611-56-9, Name is 11-Bromoundecan-1-ol, SMILES is OCCCCCCCCCCCBr, belongs to alcohols-buliding-blocks compound. In a article, author is Bach, Patrick, introduce new discover of the category.

Plasma calcium concentration during detoxification predicts neural cue-reactivity and craving during early abstinence in alcohol-dependent patients

Recent studies on the pathophysiology of alcohol dependence suggest a link between peripheral calcium concentrations and alcohol craving. Here, we investigated the association between plasma calcium concentration, cue-induced brain activation, and alcohol craving. Plasma calcium concentrations were measured at the onset of inpatient detoxification in a sample of N = 115 alcohol-dependent patients. Alcohol cue-reactivity was assessed during early abstinence (mean 11.1 days) using a functional magnetic resonance imaging (fMRI) alcohol cue-reactivity task. Multiple regression analyses and bivariate correlations between plasma calcium concentrations, clinical craving measures and neural alcohol cue-reactivity (CR) were tested. Results show a significant negative correlation between plasma calcium concentrations and compulsive alcohol craving. Higher calcium levels predicted higher alcohol cue-induced brain response in a cluster of frontal brain areas, including the dorsolateral prefrontal cortex (dlPFC), the anterior prefrontal cortex (alPFC), and the inferior (IFG) and middle frontal gyri (MFG). In addition, functional brain activation in those areas correlated negatively with craving for alcohol during fMRI. Higher peripheral calcium concentrations during withdrawal predicted increased alcohol cue-induced brain activation in frontal brain areas, which are associated with craving inhibition and cognitive control functions. This might indicate that higher plasma calcium concentrations at onset of detoxification could modulate craving inhibition during early abstinence.

Related Products of 1611-56-9, One of the oldest and most widely used commercial enzyme inhibitors is aspirin, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 1611-56-9.

Reference:
Alcohol – Wikipedia,
,Alcohols – Chemistry LibreTexts

Application of 1611-56-9, Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, 1611-56-9, Name is 11-Bromoundecan-1-ol, SMILES is OCCCCCCCCCCCBr, belongs to alcohols-buliding-blocks compound. In a article, author is Zhou, Hua, introduce new discover of the category.

Selectively Upgrading Lignin Derivatives to Carboxylates through Electrochemical Oxidative C(OH)-C Bond Cleavage by a Mn-Doped Cobalt Oxyhydroxide Catalyst

Oxidative cleavage of C(OH)-C bonds to afford carboxylates is of significant importance for the petrochemical industry and biomass valorization. Here we report an efficient electrochemical strategy for the selective upgrading of lignin derivatives to carboxylates by a manganese-doped cobalt oxyhydroxide (MnCoOOH) catalyst. A wide range of lignin-derived substrates with C(OH)-C or C(O)-C units undergo efficient cleavage to corresponding carboxylates in excellent yields (80-99 %) and operational stability (200 h). Detailed investigations reveal a tandem oxidation mechanism that base from the electrolyte converts secondary alcohols and their derived ketones to reactive nucleophiles, which are oxidized by electrophilic oxygen species on MnCoOOH from water. As proof of concept, this approach was applied to upgrade lignin derivatives with C(OH)-C or C(O)-C motifs, achieving convergent transformation of lignin-derived mixtures to benzoate and KA oil to adipate with 91.5 % and 64.2 % yields, respectively.

Application of 1611-56-9, Consequently, the presence of a catalyst will permit a system to reach equilibrium more quickly, but it has no effect on the position of the equilibrium as reflected in the value of its equilibrium constant.I hope my blog about 1611-56-9 is helpful to your research.

Reference:
Alcohol – Wikipedia,
,Alcohols – Chemistry LibreTexts

Reference of 1611-56-9, Adding some certain compound to certain chemical reactions, such as: 1611-56-9, name is 11-Bromoundecan-1-ol,molecular formula is C11H23BrO, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1611-56-9.

To a solution of 1-bromoundecanol 1 (30 g, 119.4 mmol) in DMF (150 ml_) was added NaN3 (15.5 g, 238.9 mmol) and the resulting mixture was stirred at 70 C for 12 h. The mixture was cooled to 23 C, filtered and the filtrate extracted with hexane (5 x 200 ml_). The hexanes fractions were combined and washed with H20 (2 x 100ml_), dried over anhydrous Na2S04 and concentrated under reduced pressure to afford 11-azidoundecan-1-ol 2 (24.19 g, 95%) as a colorless oil. 1H NMR (CDCI3) delta 3.62 (t, J = 6.6 Hz, 2H), 3.24 (t, J = 6.9 Hz, 2H), 1.61 -1.51 (m, 4H), 1.39-1.24 (m, 14H); 13C NMR (CDCI3) delta 63.15, 51.60, 32.89, 29.66, 29.56, 29.51 , 29.25, 28.95, 26.82, 25.84.

According to the analysis of related databases, 1611-56-9, the application of this compound in the production field has become more and more popular.

Reference:
Patent; RHODIA OPERATIONS; UNIVERSITY OF PENNSYLVANIA; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.); DONNIO, Bertrand; JISHKARIANI, Davit; DIROLL, Benjamin, T.; HOUGH, Lawrence; MURRAY, Christopher; CARGNELLO, Matteo; MALASSIS, Ludivine; (83 pag.)WO2016/201310; (2016); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Reference of 1611-56-9 , The common heterocyclic compound, 1611-56-9, name is 11-Bromoundecan-1-ol, molecular formula is C11H23BrO, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.

3,4-Dihydro-2H-pyran (21.87 g, 260 mmol) was added dropwise to a solution of 11-bromoundecanol (50.24 g, 200 mmol) and toluene-4-sulphonic acid monohydrate (80 mg, 0.4 mmol) in dichloromethane (100 ml). The reaction mixture was stirred at room temperature. After 24 h, the brown solution was filtered over a thin layer of silica gel. The filtrate was concentrated on the rotary evaporator and dried under fine vacuum. 65.85 g (196 mmol, 98% yield) of a light yellowish oil was obtained. 1H-NMR (CDCl3, 400 MHz): delta=1.23-1.37 (m, 12H), 1.37-1.47 (m, 2H), 1.48-1.64 (m, 6H), 1.65-1.76 (m, 1H), 1.77-1.90 (m, 3H), 3.35-3.42 (m, 3H), 3.46-3.53 (m, 1H), 3.70-3.75 (m, 1H), 3.84-3.90 (m, 1H), 4.56-4.58 (m, 1H). 13C-NMR (CDCl3, 100.6 MHz): delta=19.7, 25.4, 26.2, 28.2, 28.8, 29.4, 29.5, 29.6, 29.8, 30.8, 32.9, 33.9, 62.3, 67.7, 98.8.

The synthetic route of 1611-56-9 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; IVOCLAR VIVADENT AG; Moszner, Norbert; Lamparth, Iris; Bock, Thorsten; Fischer, Urs Karl; Salz, Ulrich; Rheinberger, Volker; Liska, Robert; US2014/329929; (2014); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts