Category: 111-45-5

Related Products of 111-45-5 , The common heterocyclic compound, 111-45-5, name is 2-(Allyloxy)ethanol, molecular formula is C5H10O2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.

10072] In a one-liter flask equipped with a stirring device, a dimroth condenser, a thermometer and a dropping thnnel, put were 38.25 g (0.375 mol) of ethylene glycol monoallyl ether represented by the following formula (7) and 100 g oftoluene, and heated to 70 degrees C. 0.38 Gram of a solution of a catalyst, complex of alkali-neutralized chloroplatinic acid with vinyl siloxane, in toluene, containing 0.5% of platinum, was added in the flask. Then, 185 g (0.25 mol) of the compound represented by the aforesaid formula (6) was added dropwise in the flask with the dropping funnel over one hout The reaction mixture was held at 100 degrees C. for one hour and, then, analyzed in GC. The peak of the compound represented by the aforesaid formula (6) disappeared, which means that the reaction completed. 100 Grams of ion exchanged water were added to the reaction mixture with stirring to wash it and, then, lefi standing to cause phase separation. The aqueous phase containing the excessive ethylene glycol monoallyl ether was removed. The organic phase was similarly washed twice with each 100 g of ion exchanged water and, then, the toluene in the organic phase was stripped off under a reduced pressure to obtain 193.7 g (0.23 mol) of a colorless and transparent liquid, silicone compound representedby the following formula (8). The yield was 92%. The ratio of the silicone compound represented by the following formula (8) in the obtained product was 98.1 mass %, as determined in GC.

The synthetic route of 111-45-5 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; SHIN-ETSU CHEMICAL CO., LTD.; KUDO, Muneo; US2015/361114; (2015); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Related Products of 111-45-5, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 111-45-5, name is 2-(Allyloxy)ethanol. This compound has unique chemical properties. The synthetic route is as follows.

To a solution of sodium hydroxide (4.6 g, 115 mmol) in water (25 mL) was added a solution of ethyleneglycol monoallyl ether (10.0 g, 98 mmol) in THF (50 mL) at 0 C (ice/water bath). A solution of p-toluene sulfonyl chloride (17.9 g, 93 mmol) in THF (40 mL) was added dropwise to the alkaline solution at 0 oC. After completion of addition, the reaction mixture was stirred for 1 h at room temperature and poured into ice/water. The organic materials were extracted with hexane and hexane layer was washed with brine, dried with MgSO4 , and evaporated to leave a residue which was distilled under vacuum to give 22.4 g of 2-(p-tolylsulfonyloxy)ethyl propenyl ether (1b) as a colorless oil in 93% yield (22.4 g).

According to the analysis of related databases, 111-45-5, the application of this compound in the production field has become more and more popular.

Reference:
Article; Kultyshev, Roman G.; Kawanishi, Yuji; Nishioka, Masateru; Miyazawa, Akira; Synthetic Communications; vol. 44; 4; (2014); p. 556 – 563;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts