Author: tianli

Arzumanyan, Ashot V. published the artcileCopper-Catalyzed Oxidation of Hydrosilanes: A New Method for the Synthesis of Alkyl- and Siloxysilanols, Formula: C6H16OSi, the publication is Synlett (2018), 29(4), 489-492, database is CAplus.

A simple method for the preparation of silanols from the corresponding hydrosilanes is reported. The method employs a com. available oxidizing system based on CuCO ₃/ t-BuOOH _(aq)under relatively mild conditions (80 °C, atm. pressure) with acetonitrile as the solvent. Furthermore, we present a method that permits the Si-H group to be oxidized to a Si-OH group not only in triethylsilane, but also in bis(trimethylsiloxy)methylsilane, a siloxy derivative of hydrosilane. The products were isolated in gram amounts in yields of 61-73%.

Synlett published new progress about 597-52-4. 597-52-4 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is Triethylsilanol, and the molecular formula is C6H16OSi, Formula: C6H16OSi.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Pinto, Eduardo Costa published the artcileDevelopment and validation of a stability-indicating HPLC method for topiramate using a mixed-mode column and charged aerosol detector, Computed Properties of 20880-92-6, the publication is Journal of Separation Science (2018), 41(8), 1716-1725, database is CAplus and MEDLINE.

The anal. of topiramate in the presence of its main degradation products is challenging due to the absence of chromophore moieties and their wide range of polarity. Mixed-mode chromatog. has been used in such cases because it combines two or more modes of separation Charged aerosol detector is also an alternative since its detection is independent of optical properties and analyte ionization. This study is aimed to develop and validate two new stability-indicating methods by high-performance liquid chromatog. for the main degradation products of topiramate using mixed-mode chromatog. and a charged aerosol detector. Method 1 employed an Acclaim Trinity P1 column (3.0 mm × 150 mm, 2.7 μm) with a mobile phase comprising of 80% ammonium acetate buffer (20 mM, pH 4.0) and 20% methanol at a flow rate of 0.5 mL/min at 35°C. Method 2 utilized a C18 Acclaim 120 column (4.6 mm × 250 mm; 5 μm) with ACN/water (50:50) at a flow rate of 0.6 mL/min at 50°C. Validation of the two methods demonstrated excellent performance with respect to linearity, precision, accuracy, and selectivity. The limits of detection for topiramate, fructose, sulfate, sulfamate, and compound A were 2.97, 12.08, 4.02, 13.91, and 3.94 μg/mL, resp.

Journal of Separation Science published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C12H20O6, Computed Properties of 20880-92-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Garcia-Abuin, Alicia published the artcileCarbon dioxide capture with tertiary amines. Absorption rate and reaction mechanism, Category: alcohols-buliding-blocks, the publication is Journal of the Taiwan Institute of Chemical Engineers (2017), 356-362, database is CAplus.

Present work analyzes the overall carbon dioxide chem. absorption process using tertiary amines in aqueous solution, taking into account absorption rate exptl. data and ¹³C and ¹H NMR. These studies try to detect the causes because different behaviors are obtained for absorption curves at different carbon dioxide loadings. The combined use of these techniques allows to evaluate the weight of different variables (chem. kinetics, mechanism, hydrodynamics, etc) upon the absorption overall process.

Journal of the Taiwan Institute of Chemical Engineers published new progress about 122-20-3. 122-20-3 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment, name is Triisopropanolamine, and the molecular formula is C9H21NO3, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Cavaca, Lidia A. S. published the artcilePreparation of Thioaminals in Water, Product Details of C8H10S, the publication is Molecules (2022), 27(5), 1673, database is CAplus and MEDLINE.

In this work, the formation of thioaminals RSCH(R¹)N(R²)(R³) [R = Ph, benzyl, Pr, etc.; R¹ = furan-2-yl, Ph, 4-bromophenyl, etc. ; R² = benzyl; R³ = benzyl ; R²R³ = -(CH₂)₅-, -(CH₂)₂O(CH₂)₂-, -(CH₂)₂N(CH₃)(CH₂)₂-] in water promoted by copper(II) triflate was described.

Molecules published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Product Details of C8H10S.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Coutinho, Rodrigo published the artcileOptimisation of the conditions of dispersive liquid-liquid microextraction for environmentally friendly determination of bisphenols and benzophenone in complex water matrices by LC-MS/MS, HPLC of Formula: 80-09-1, the publication is Microchemical Journal (2022), 107636, database is CAplus.

Due to well-known risks to human and environmental health, the increasing presence of several micropollutants even in very low concentrations in environmental matrixes requires sustainable and advanced anal. methods to expand monitoring programs, particularly for water quality control. The objective of this study was to optimize the conditions of the dispersive liquid-liquid microextraction (DLLME) for a combined group of emerging micropollutants (bisphenol A, bisphenol S, bisphenol F, bisphenol AF and benzophenone) in complex water matrixes. Ten variables were chosen as the most important for DLLME procedure and the Design of Experiments (DoE) approach was applied to find the most relevant variables and optimize the DLLME procedure. The optimized DLLME was then, applied to real complex water samples including raw and treated wastewaters and surface water in Rio de Janeiro city, Brazil, and the extracted samples were analyzed by ultra-performance liquid chromatog.-tandem mass spectrometry (UPLC-MS/MS). The variables vortex mixing time (VMT), Dispersive Solvent Volume (DSV) and Extractor Solvent Volume (ESV) are the most important among the variables evaluated. The recovery efficiencies ranged from 60 to 120% after optimization the amounts of target compounds found in the five real aqueous matrixes varied from 0.005 to 150μg L-1. The association of optimized DLLME with the UPLC-MS/MS met the validation requirements adopted and generated anal. results of high quality. The advantages of this extraction technique include reduction of cost per anal.; low volume of samples and low volume of solvent required; no need to use cartridges; reduction of waste generation. The method is, therefore, suitable to process large numbers of samples, particularly in countries with limited budgets for environmental monitoring.

Microchemical Journal published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C12H10O4S, HPLC of Formula: 80-09-1.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Jeminejs, Andris published the artcileApplication of Azide-Tetrazole Tautomerism and Arylsulfanyl Group Dance in the Synthesis of Thiosubstituted Tetrazoloquinazolines, Synthetic Route of 4410-99-5, the publication is Synthesis (2021), 53(8), 1443-1456, database is CAplus.

Nucleophilic aromatic substitution reaction between 4-arylthio-2-chloroquinazolines I (Ar = C₆H₅, 4-BrC₆H₄, 4-FC₆H₄, 4-ClC₆H₄, 4-CH₃C₆H₄) and NaN₃ takes place with an unusual sulfanyl group dance and leads to the formation of 5-(arylthio)tetrazolo[1,5-c]-quinazolines II, which do not form the azide tautomer and do not undergo CuAAC reactions with alkynes. On the other hand, 5-azidotetrazolo[1,5-a]quinazoline (formally described as 2,4-diazidoquinazoline) undergoes regioselective nucleophilic aromatic substitution with thiols at C5 and forms 5-(alkyl/arylthio)tetrazolo[1,5-a]quinazolines III (R¹ = cyclopentyl, C₆H₅, CH₂C₆H₅, etc.), the structure of which has been proved by X-ray crystallog. The latter exist in tautomeric equilibrium with their 2-azidoquinazoline form, which provides possibility for copper-catalyzed azide-alkyne 1,3-dipolar cycloaddition reaction, leading to the 4-alkyl/arylthio-2-(1H-1,2,3-triazol-1-yl)quinazolines IV (R² = C₆H₅, cyclopropyl, Bu, etc.).

Synthesis published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Synthetic Route of 4410-99-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Blandamer, Michael J. published the artcileMechanism and solvent reorganization accompanying hydrolyses of anchimerically assisted alkyl halides in water, SDS of cas: 2588-77-4, the publication is Journal of the American Chemical Society (1969), 91(10), 2678-83, database is CAplus.

This paper deals with the problem of solvent reorganization, anchimeric assistance, and mechanism for hydrolysis of 9 alkyl halides where the neighboring group is -OH, -OMe, or -SMe. By using the temperature coefficient of the enthalpy as a gauge of relative solvent reorganization, we show that the transition state in the hydrolysis of those alkyl halides giving evidence of anchimeric assistance resembles that for an SN1 mechanism. This conclusion was supported in one case by 13C labeling experiments in spite of product analysis seemingly favoring SN2 nucleophilic displacement by the solvent.

Journal of the American Chemical Society published new progress about 2588-77-4. 2588-77-4 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is 2-Methyl-3-bromo-2-butanol, and the molecular formula is C5H11BrO, SDS of cas: 2588-77-4.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Ginzburg, O. F. published the artcileProducts of condensation of arylcarbinols with 1-phenyl-3-methyl-5-pyrazolone. III, Product Details of C19H14O2, the publication is Zhurnal Obshchei Khimii (1957), 993-7, database is CAplus.

cf. C.A. 49, 1049a. Refluxing 0.3 g. 1-phenyl-3-methyl-5-pyrazolone and 0.4 g. 9-phenylxanthhydrol in dry MeOH 2 hrs. gave 95.8% 9-phenyl-9-(1-phenyl-3-methyl-4,5-dihydro-5-oxo-4-pyrazolyl)xanthene (I), m. 220-1°; also formed in AcOH solution The product can be dissolved in aqueous alc. NaOH, refluxed, and regenerated on acidification; it is also recovered readily after being refluxed in AcOH containing a little HCl. I (0.43 g.) in 10 ml. 60% EtOH containing 1 g. NaOH was treated with 0.001 mole diazosulfanilic acid and the resulting precipitate separated; the filtrate contained the azo dye from sulfanilic acid and the pyrazolone as shown by the absorption spectrum, while the precipitate was 9-phenylxanthhydrol, m. 159°. 1-Phenyl-3-methyl-4-triphenylmethyl-5-pyrazolone treated similarly gave the same azo compound in solution and a precipitate of Ph₃COH. Similar results were obtained with 1-phenyl-3-methyl-4-(9-phenyl-10-methyl-9,10-dihydro-9-acridyl)-5-pyrazolone (II), diphenyl-p-dimethylaminophenyl(1-phenyl-3-methyl-4,5-dihydro-5-oxo-4-pyrazolyl)methane, and bis(p-dimethylaminophenyl)phenyl(1-phenyl-3-methyl-4,5-dihydro-5-oxo-4-pyrazolyl)methane (III), all of which yielded the same azo compound in the solution Conductivity of II and III was determined in PhNO₂ over a period of time; a constant value is established only after 24 hrs. The results indicate that the increasing conductivity of such solutions is caused by cleavage between the 4-position of the pyrazolone and the arylcarbinyl group with formation of expected ionic charges. The process is unusually slow.

Zhurnal Obshchei Khimii published new progress about 596-38-3. 596-38-3 belongs to alcohols-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Benzene,Alcohol, name is 9-Phenyl-9H-xanthen-9-ol, and the molecular formula is C19H14O2, Product Details of C19H14O2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Gogoi, Nibedita published the artcileGrafting of Ru(III) complex onto nanosilica and its implication as heterogeneous catalyst for aerobic oxidative hydroxylation of arylboronic acids, Application In Synthesis of 17236-59-8, the publication is Tetrahedron Letters (2016), 57(36), 4050-4052, database is CAplus.

An ecofriendly and highly efficient protocol for aerobic oxidative hydroxylation of aryl and heteroaryl boronic acids catalyzed by Ru(III) amidine complex immobilized on nanosilica, derived from rice husk, has been developed. The main significance of this protocol is the base free and aerobic reaction condition at room temperature, short reaction time, aqueous reaction medium, and excellent yield of the product. This heterogeneous catalyst is reusable up to sixth cycle without loss in activity.

Tetrahedron Letters published new progress about 17236-59-8. 17236-59-8 belongs to alcohols-buliding-blocks, auxiliary class Thiophene,Alcohol, name is Thiophen-3-ol, and the molecular formula is C4H4OS, Application In Synthesis of 17236-59-8.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Yildirim, Ayhan published the artcileD-Fructose-Derived Acetonide as a Green Neutral Organocatalyst for Proficient One-Pot and Three-Component Preparation of 1,3-Benzoxazine Monomers, Product Details of C12H20O6, the publication is ChemistrySelect (2020), 5(23), 6971-6977, database is CAplus.

A series of 1,3-benzoxazine monomers were successfully synthesized by simple one-pot and three-component condensation of phenol, paraformaldehyde and varying types of primary aliphatic and aromatic amines in a molar ratio of 1 : 2 : 1 and in the presence of non-acidic 2,3;4,5-di-O-isopropylidene-β-D-fructopyranose as an effective green carbohydrate based organocatalyst obtained from renewable feedstock. This multicomponent method provided a convenient fast approach for the construction of valuable 1,3-benzoxazine monomers (8 examples) with moderate to excellent yields. The chem. structures of the synthesized benzoxazines were confirmed by FTIR, ¹H NMR, ¹³C NMR spectra and elemental anal.

ChemistrySelect published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C23H20BN, Product Details of C12H20O6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts