Author: tianli

Deng, Danfeng published the artcileNNN-Ruthenium Catalysts for the Synthesis of Pyridines, Quinolines, and Pyrroles by Acceptorless Dehydrogenative Condensation, Formula: C4H11NO, the publication is Organometallics (2018), 37(14), 2386-2394, database is CAplus.

The bidentate 6-picolinoyl 2,2′-bipyridine (bpy) ruthenium complex (6-HOC₅H₃NCO-bpy)Ru(CO)₂Cl₂ (2) transforms to a tridentate product I (3, L¹ = L² = Cl; n = 0), which further reacted with MeONa in the presence of PPh₃ to convert to two complexes, (4, 5; shown as I, 4, L¹ = L² = PPh₃, n = 1; 5, L¹ = Cl, L² = PPh₃, n = 0), via -OH deprotonation. The catalytic coupling cyclizations of secondary alcs. with amino alcs. were investigated, and complex 3 exhibited the highest activity. The coupling reactions proceeded in air with only 0.2 mol % catalyst loading and had a broad scope for the synthesis of pyridines, quinolones, and pyrroles.

Organometallics published new progress about 96-20-8. 96-20-8 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 2-Aminobutan-1-ol, and the molecular formula is C4H11NO, Formula: C4H11NO.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Wolfe, Aaron J. published the artcileInterrogating Detergent Desolvation of Nanopore-Forming Proteins by Fluorescence Polarization Spectroscopy, Safety of (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(octylthio)tetrahydro-2H-pyran-3,4,5-triol, the publication is Analytical Chemistry (Washington, DC, United States) (2017), 89(15), 8013-8020, database is CAplus and MEDLINE.

Understanding how membrane proteins interact with detergents is of fundamental and practical significance in structural and chem. biol. as well as in nanobiotechnol. Current methods for inspecting protein-detergent complex (PDC) interfaces require high concentrations of protein and are of low throughput. Here, the authors describe a scalable, spectroscopic approach that uses nanomolar protein concentrations in native solutions This approach, which is based on steady-state fluorescence polarization (FP) spectroscopy, kinetically resolves the dissociation of detergents from membrane proteins and protein unfolding. For satisfactorily solubilizing detergents, at concentrations much greater than the critical micelle concentration (CMC), the fluorescence anisotropy was independent of detergent concentration In contrast, at detergent concentrations comparable with or below the CMC, the anisotropy readout underwent a time-dependent decrease, showing a specific and sensitive protein unfolding signature. Functionally reconstituted membrane proteins into a bilayer membrane confirmed predictions made by these FP-based determinations with respect to varying refolding conditions. From a practical point of view, this 96-well anal. approach will facilitate a massively parallel assessment of the PDC interfacial interactions under a fairly broad range of micellar and environmental conditions. The authors expect that these studies will potentially accelerate research in membrane proteins pertaining to their extraction, solubilization, stabilization, and crystallization, as well as reconstitution into bilayer membranes.

Analytical Chemistry (Washington, DC, United States) published new progress about 85618-21-9. 85618-21-9 belongs to alcohols-buliding-blocks, auxiliary class Tetrahydropyran,Chiral,sulfides,Alcohol, name is (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(octylthio)tetrahydro-2H-pyran-3,4,5-triol, and the molecular formula is C18H24N6O6S4, Safety of (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(octylthio)tetrahydro-2H-pyran-3,4,5-triol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Shinkai, Takahiro published the artcileInfrared spectroscopy and theoretical structure analyses of protonated fluoroalcohol clusters: the impact of fluorination on the hydrogen bond networks, Application In Synthesis of 2240-88-2, the publication is Physical Chemistry Chemical Physics (2022), 24(20), 12631-12644, database is CAplus and MEDLINE.

To explore the impact of fluorination on the hydrogen bond networks of protonated alkylalcs., IR spectroscopy and theor. computations of protonated 2,2,2-trifluoroethanol clusters, H⁺(TFE)_n, (n = 4-7), were performed. It has been demonstrated that the development of the hydrogen bond networks from a linear type to cyclic types occurs in this size region for the protonated alkylalc. clusters. In contrast, IR spectroscopy of H⁺(TFE)_n in the OH/CH stretch region clearly indicated that the linear type structures are held in the whole size range, irresp. of temperature of the clusters. The extensive stable isomer structure search of H⁺(TFE)_n based on our latest sampling approach supported the strong preference of the linear type hydrogen bond networks. Detailed analyses of the free OH stretching vibrational bands evidenced the intra- and intermol. OH···FC interactions in the clusters. In addition, IR spectra of protonated clusters of 2,2-difluoroethanol, 2,2-difluoropropanol, and 3,3,3-trifluoropropanol were measured for n = 4 and 5, and their spectra also indicated the effective inhibition of the cyclic hydrogen bond network formation by the fluorination.

Physical Chemistry Chemical Physics published new progress about 2240-88-2. 2240-88-2 belongs to alcohols-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Aliphatic hydrocarbon chain,Alcohol, name is 3,3,3-Trifluoropropan-1-ol, and the molecular formula is C10H10N2, Application In Synthesis of 2240-88-2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Wang, TsingHai published the artcileImpact of microporous structures of esterified cellulose filter papers on Co (II) rejection in cross-flow microfiltration, Formula: C8H8O3, the publication is Separation and Purification Technology (2021), 119738, database is CAplus.

The Donnan exclusion effect is a unique phenomenon in which ions are electrostatically repelled by a surface bearing an identical charge. In this study, cellulose filter papers were esterified by ten different organic acids to systematically evaluate how surface properties regulate the development of the Donnan exclusion effect and subsequent Co(II) rejection. Among the esterified cellulose filter papers, those exhibiting high Co(II) rejection (>80% in 1.0 mg/L Co(II) in 1.0 mM NaCl background electrolyte solution) were noted to simultaneously possess pos. zeta potential when in contact with Co(II), low adsorption affinity, and a relatively high microporous environment. This behavior could be explained by the Gouy-Chapman-Stern (GCS) model, in which the ion retention in the overlapped elec. double layers (EDLs) regulates the zeta potential development and consequently the Co(II) rejection. In addition to introducing reactive carbonyl and carboxyl groups, we suggest that the creation of a relatively microporous environment is essential for high Co(II) rejection. Our results are valuable for developing low-energy filtration systems for environmentally friendly water and wastewater treatment.

Separation and Purification Technology published new progress about 90-64-2. 90-64-2 belongs to alcohols-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Alcohol,Natural product, name is 2-Hydroxy-2-phenylacetic acid, and the molecular formula is C6H3ClFNO2, Formula: C8H8O3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Chang, Gung-Pei published the artcileHigh-performance semiconductors based on oligocarbazole-thiophene derivatives for solution-fabricated organic field-effect transistors, Recommanded Product: 5,5′-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,2′-bithiophene, the publication is Thin Solid Films (2013), 291-298, database is CAplus.

Oligocarbazole-thiophenes based on a constant conjugate backbone (carbazole-bithiophene-carbazole) with various n-alkyl chain lengths were prepared for application to organic field-effect transistors (OFETs). The lengths of the n-alkyl substitutions attached on 9-position of carbazole moieties were Me (CCzT2), hexyl (C6CzT2), dodecyl (C12CzT2), and octadecyl (C18CzT2), called CxCzT2. Variations of n-alkyl chain lengths probably figure out the optimization of OFET performance via solution fabrication of the active layer. Before fabricating OFET devices, the thermal, optical, and electrochem. properties of CxCzT2 were fully characterized with TGA, DSC, UV-visible spectroscopy, and cyclic voltammetry to realize the relations of the structure to the properties. After fabricating CxCzT2 on Si/SiO₂ substrates via solution casting, the thin film morphologies were also studied with polarizing optical microscopy, at. force microscopy, and x-ray diffraction to study the structural relation to OFET performance. A higher hole mobility was observed with C12CzT2 (3.6 × 10^-2 cm² V^-1 s^-1) due to its liquid crystal properties, and the hole mobility could be further improved to 1.2 × 10^-1 cm² V^-1 s^-1 by the introduction of a phenyl-self-assembled monolayer on the Si/SiO₂ substrates. The excellent OFET performances of C12CzT2 by solution-fabrication could be considered as a promising candidate for high-end OFET application.

Thin Solid Films published new progress about 239075-02-6. 239075-02-6 belongs to alcohols-buliding-blocks, auxiliary class Thiophene,Boronic acid and ester,Boronate Esters, name is 5,5′-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,2′-bithiophene, and the molecular formula is C20H28B2O4S2, Recommanded Product: 5,5′-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,2′-bithiophene.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Kucinski, Krzysztof published the artcileO-Metalation of silanols and POSS silanols over Amberlyst-15 catalyst: A facile route to unsymmetrical siloxanes, borasiloxanes and germasiloxanes, Name: Triisopropylsilanol, the publication is Inorganica Chimica Acta (2019), 261-266, database is CAplus.

A simple and highly practical Amberlyst-catalyzed direct O-metalation of silanols, POSS silanols and alkoxysilanes under mild conditions is proposed. This protocol can be applied to the synthesis of a wide range of important organosilicon derivatives such as siloxanes, germasiloxanes, borasiloxanes and functionalized silsesquioxanes. It is worth noting that Amberlyst-15 can be reused for further experiments and its catalytic activity in this process is well-preserved for several recycling steps.

Inorganica Chimica Acta published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C9H22OSi, Name: Triisopropylsilanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Kucinski, Krzysztof published the artcileA Highly Effective Route to Si-O-Si Moieties through O-Silylation of Silanols and Polyhedral Oligomeric Silsesquioxane Silanols with Disilazanes, Quality Control of 17877-23-5, the publication is ChemSusChem (2019), 12(5), 1043-1048, database is CAplus and MEDLINE.

A simple and highly practical catalyst-free O-silylation of silanols with com. available disilazanes has been developed under mild conditions. In the case of polyhedral oligomeric silsesquioxane (POSS) silanols and some other silanols, it was necessary to use catalytic amounts of inexpensive Bi(OTf)₃ as addnl. catalyst. This efficient chlorine-free protocol involves the synthesis of a wide range of important organosilicon derivatives such as unsym. disiloxanes and functionalized silsesquioxanes.

ChemSusChem published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C9H22OSi, Quality Control of 17877-23-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Kazmierczak, Joanna published the artcileNafion as effective and selective heterogeneous catalytic system in O-metalation of silanols and POSS silanols, Quality Control of 17877-23-5, the publication is Journal of Catalysis (2018), 95-103, database is CAplus.

Herein, we demonstrate the first use of Nafion as heterogeneous catalyst in O-metalation of compounds containing Si-OH moiety (silanols and POSS silanols). Our methodol. permits efficient and highly selective formation of Si-O-E bonds (E = Si, Ge, B) within mols., under mild conditions with excellent yields. This approach allows syntheses of various unsym. disiloxanes, germasiloxanes and borasiloxanes, as well as introduction of a wide range of functional groups into silsesquioxanes. It is worth noting that Nafion can be reused for further experiments and its catalytic activity in this process is well-maintained for more than 10 recycling steps, without a decrease in yield or selectivity.

Journal of Catalysis published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C9H22OSi, Quality Control of 17877-23-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Kucinski, K. published the artcileChemoselective and Catalyst-Free O-Borylation of Silanols: A Facile Access to Borasiloxanes, Application In Synthesis of 597-52-4, the publication is ChemSusChem (2017), 10(23), 4695-4698, database is CAplus and MEDLINE.

This paper demonstrates the 1st highly chemoselective syntheses of various borasiloxanes from hydroboranes and silanols, achieved through catalyst-free dehydrogenative coupling at room temperature This green protocol, which uses easily accessible reagents, allows for the obtaining of borasiloxanes under air atm. and solvent-free conditions.

ChemSusChem published new progress about 597-52-4. 597-52-4 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is Triethylsilanol, and the molecular formula is C6H16OSi, Application In Synthesis of 597-52-4.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Kucinski, K. published the artcileChemoselective and Catalyst-Free O-Borylation of Silanols: A Facile Access to Borasiloxanes, Recommanded Product: Triisopropylsilanol, the publication is ChemSusChem (2017), 10(23), 4695-4698, database is CAplus and MEDLINE.

This paper demonstrates the 1st highly chemoselective syntheses of various borasiloxanes from hydroboranes and silanols, achieved through catalyst-free dehydrogenative coupling at room temperature This green protocol, which uses easily accessible reagents, allows for the obtaining of borasiloxanes under air atm. and solvent-free conditions.

ChemSusChem published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C9H22OSi, Recommanded Product: Triisopropylsilanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts