Author: tianli

Zhao, Pinjing published the artcileDirect Observation of β-Aryl Eliminations from Rh(I) Alkoxides, Quality Control of 596-38-3, the publication is Journal of the American Chemical Society (2006), 128(10), 3124-3125, database is CAplus and MEDLINE.

Rhodium(I) tris-phosphine triaryl alkoxides undergo β-Ph elimination, affording phenylrhodium complexes and diaryl ketones. Ligand substitution of [(PEt₃)₂Rh[N(SiMe₃)₂]] with ROH in the presence of PEt₃ afforded either [(PEt₃)₂RhOR] (2a,c; R = CPh₃, 9-phenyl-9-xanthenyl) or [(PEt₃)₃RhOR] [3b–e; R = CMePh₂, 9-phenyl-9-xanthenyl, 9-phenyl-9H-fluoren-9-yl, CMe₂(CF₃)]. Reaction of 2a with an excess of PEt₃ gave [(PEt₃)₃RhPh] and Ph₂CO; Ph β-elimination from 3b–d gave similarly [(PEt₃)₃RhPh] and acetophenone, xanthone and 9-fluorenone, resp. Kinetic results are most consistent with irreversible β-Ph elimination from a bisphosphine-ligated rhodium alkoxide complex. Such bisphosphine complexes result from ligand dissociation from the tris-phosphine complexes and were isolated in some cases. The bisphosphine complexes are stabilized by Rh-Ph interactions, as evidenced by an x-ray structure of 2a, and this structure with a metal-aryl interaction likely illustrates the pathway for C-C bond cleavage.

Journal of the American Chemical Society published new progress about 596-38-3. 596-38-3 belongs to alcohols-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Benzene,Alcohol, name is 9-Phenyl-9H-xanthen-9-ol, and the molecular formula is C6H13N3O2, Quality Control of 596-38-3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Maegawa, Yoshifumi published the artcileIridium-bipyridine periodic mesoporous organosilica catalyzed direct C-H borylation using a pinacolborane, Name: 5,5′-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,2′-bithiophene, the publication is Dalton Transactions (2015), 44(29), 13007-13016, database is CAplus and MEDLINE.

Heterogeneous catalysis for direct C-H borylation of arenes and heteroarenes in the combination of iridium (Ir) complex fixed on periodic mesoporous organosilica containing bipyridine ligands within the framework (Ir-BPy-PMO) and pinacolborane (HBpin) is reported. Ir-BPy-PMO showed higher catalytic activity toward the borylation of benzene with inexpensive HBpin compared to expensive bis(pinacolato)diboron (B₂pin₂). The precatalyst could be handled without the use of a glove box. The catalyst was easily recovered from reaction mixtures by simple filtration under air. The recovered catalyst still showed good catalytic activity for at least three more times for the borylation of benzene. A variety of arenes and heteroarenes were successfully borylated with high boron efficiency by Ir-BPy-PMO using HBpin, whereas almost no activity was observed for borylation of some heteroarenes with B₂pin₂. The system using Ir-BPy-PMO and HBpin was also utilized in syntheses of multi-boronated thiophene-based building blocks containing ladder-, acenefused-, and fused-thiophene skeletons. The combination of a stable and reusable solid catalyst and inexpensive HBpin is expected to be superior to conventional approaches for the development of industrial applications.

Dalton Transactions published new progress about 239075-02-6. 239075-02-6 belongs to alcohols-buliding-blocks, auxiliary class Thiophene,Boronic acid and ester,Boronate Esters, name is 5,5′-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,2′-bithiophene, and the molecular formula is C20H28B2O4S2, Name: 5,5′-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,2′-bithiophene.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Hayashi, Mikihiro published the artcileAchievement of a Highly Rapid Bond Exchange for Self-Catalyzed Polyester Vitrimers by Incorporating Tertiary Amino Groups on the Network Strands, HPLC of Formula: 111-29-5, the publication is ACS Applied Polymer Materials (2021), 3(9), 4424-4429, database is CAplus.

Herein, we describe the preparation of a self-catalyzed polyester vitrimer containing tertiary amino groups on the network strands that overcomes the significantly slow bond exchange often encountered in the reported systems. Starting from a polyester precursor bearing both carboxy and tertiary amino side groups, a selective reaction of the carboxyl groups with diepoxy cross-linkers affords a network that possesses hydroxy and tertiary amino groups. The tertiary amino groups on the network strands effectively work as internal catalysts for the trans-esterification bond exchange. Because of the high mobility of the incorporated internal amine catalyst, the bond exchange in the vitrimer material was much more rapid (more than 20 times) than that in reported self-catalyzed polyester vitrimers.

ACS Applied Polymer Materials published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C5H12O2, HPLC of Formula: 111-29-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Sandanayake, K. R. A. Samankumara published the artcileMolecular fluorescence sensor for saccharides based on amino coumarin, Name: 3-(Methylamino)phenol, the publication is Chemistry Letters (1995), 139-40, database is CAplus.

The intramol. neighboring group interaction of the amino group of the 7-aminocoumarin moiety with phenylboronic acid gave fluorescence intensity and spectral changes upon saccharide binding which could be used in fluorescence mapping of saccharides in biol. cells.

Chemistry Letters published new progress about 14703-69-6. 14703-69-6 belongs to alcohols-buliding-blocks, auxiliary class Amine,Benzene,Phenol, name is 3-(Methylamino)phenol, and the molecular formula is C7H9NO, Name: 3-(Methylamino)phenol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Herbinski, Aurelien published the artcileEco-conception of Highly Salt-Tolerant Alkyl Ether Carboxylate Hydrotropes with a Glyceryl Spacer, Name: 3-((2-Ethylhexyl)oxy)propane-1,2-diol, the publication is Chemistry – A European Journal (2022), 28(28), e202200274, database is CAplus and MEDLINE.

New alkyl ether carboxylates with a glyceryl spacer instead of ethylene glycol units had been synthesized using environmentally friendly methodol. A cascade synthesis of acetalization and hydrogenolysis was developed to obtain products containing an alkyl chain linked to a glycerol unit bearing a polar carboxylate head. These products were methylated by using tri-Me phosphate to observe the influence of a free or methoxylated alc. on the physicochem. properties. Finally, saponification gave the carboxylate anionic group of the new hydrotropes. Studying the amphiphilicity, the tolerance to sodium and calcium ions, and the solubilizing power of these bio-based ionic/nonionic hydrotropes has shown that they exhibited significantly improved application properties compared to similar petro-based hydrotropes.

Chemistry – A European Journal published new progress about 70445-33-9. 70445-33-9 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is 3-((2-Ethylhexyl)oxy)propane-1,2-diol, and the molecular formula is C11H24O3, Name: 3-((2-Ethylhexyl)oxy)propane-1,2-diol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Dimitrova, Maria published the artcileReactivity descriptors for the hydrogen bonding ability of aliphatic alcohols, HPLC of Formula: 2240-88-2, the publication is Journal of Molecular Structure (2003), 657(1-3), 317-324, database is CAplus.

A series of 18 aliphatic alcs. and their hydrogen-bonded complexes with ammonia are studied by applying d. functional theory computations at the B3LYP/631G(d,p) level. Theor. determined electronic parameters-partial at. charges and electrostatic potential at nuclei (EPN)-are employed to characterize the reactivity of the monomer alcs. The variations of binding energy are also interpreted in terms of the well-known exptl. solvatochromic parameters, α. It is shown that both the exptl. α constants and EPN values characterize quant. the reactivity of the studied mols. toward the complexation process. A linear link between α constants and EPN values was also found.

Journal of Molecular Structure published new progress about 2240-88-2. 2240-88-2 belongs to alcohols-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Aliphatic hydrocarbon chain,Alcohol, name is 3,3,3-Trifluoropropan-1-ol, and the molecular formula is C3H5F3O, HPLC of Formula: 2240-88-2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Cheng, Feixiong published the artcileIn Silico Assessment of Chemical Biodegradability, COA of Formula: C22H38O2, the publication is Journal of Chemical Information and Modeling (2012), 52(3), 655-669, database is CAplus and MEDLINE.

Biodegradation is the principal environmental dissipation process. Due to a lack of comprehensive exptl. data, high study cost and time-consuming, in silico approaches for assessing the biodegradable profiles of chems. are encouraged and is an active current research topic. We developed in-silico methods to estimate chem. biodegradability in the environment. At SST, 1440 diverse compounds tested under the Japanese Ministry of International Trade and Industry (MI-TI) protocol were used. Four different methods (support vector machine, k-nearest neighbor, naive B-ayes, and CU.5 decision tree) were used to build the combinatorial classification probability models of ready vs. not ready biodegradability using physicochem. descriptors and fingerprints sep. The overall predictive accuracies of the best models were >80% for the external test set of 164 diverse compounds Some privileged substructures were further identified for ready or not ready biodegradable chems. by combining information gain and substructure fragment anal. Here, 27 new predicted chems. were selected for exptl. assay through the Japanese MI-TI test protocols, which validated that all 27 compounds were predicted correctly. The predictive accuracies of our models outperform the commonly used software of the E-PI Suite. Our study provided critical tools for early assessment of biodegradability of new organic chems. in environmental hazard assessment.

Journal of Chemical Information and Modeling published new progress about 903-19-5. 903-19-5 belongs to alcohols-buliding-blocks, auxiliary class Benzene,Phenol, name is 2,5-Bis(2,4,4-trimethylpentan-2-yl)benzene-1,4-diol, and the molecular formula is C22H38O2, COA of Formula: C22H38O2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Tolmacheva, Irina A. published the artcileSynthesis and evaluation of antiviral activities of triterpenic conjugates with 2-aminobutan-1-ol as potent microbicidal agents, Recommanded Product: 2-Aminobutan-1-ol, the publication is Medicinal Chemistry Research (2019), 28(10), 1648-1660, database is CAplus.

The effect of the synthetic modifications of the triterpenic A ring on the level of antiviral activity of triterpenic C3, C28 amides with a residue of racemic, (S), or (R)-enantiomeric 2-aminobutan-1-ol against herpes simplex viruses type I (HSV-I) and type II (HSV-II), as well as against human immunodeficiency virus type I (HIV-1) was investigated. The 2,3-secolupane racemic amide 5a was selected as a potent microbicidal agent with the highest virus inhibitory (against HSV-I and HSV-II) and virucidal (against HSV-1 and HIV-1) actions, the antiviral activity of which was provided by the (S)-enantiomeric conjugate 5b.

Medicinal Chemistry Research published new progress about 96-20-8. 96-20-8 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 2-Aminobutan-1-ol, and the molecular formula is C19H21N3O, Recommanded Product: 2-Aminobutan-1-ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Aliaga-Lavrijsen, Melanie published the artcileHydrolysis and Methanolysis of Silanes Catalyzed by Iridium(III) Bis-N-Heterocyclic Carbene Complexes: Influence of the Wingtip Groups, Name: Triethylsilanol, the publication is Organometallics (2015), 34(11), 2378-2385, database is CAplus.

New [Ir(CH₃CN)₂(I)₂{κC,C’-bis(NHC)}]BF₄ complexes featuring bis-NHC ligands with a methylene bridge and different N substitution (-CH₂CH₂CH₂CH₃ and -CH₂CH₂OPh) were synthesized. NMR studies and x-ray diffraction structures evidenced that the wingtip group -CH₂CH₂OPh presents a hemilabile behavior in solution, with the oxygen atom coordinating and dissociating at room temperature, which contrasts with the strong coordination of the ether functions in the complex [Ir(I)₂{κC,C’,O,O’-bis(NHC^OMe)}]BF₄ (bis(NHC^OMe) = methylenebis(N,N’-bis(2-methoxyethyl)imidazol-2-ylidene)), previously reported by us. These complexes proved to be efficient catalysts for the hydrolysis and methanolysis of silanes, affording mol. hydrogen and silyl alcs. or silyl ethers as the main reaction products in excellent yields. The hydrogen generation rates were very much dependent on the nature of the hydrosilane and the coordination ability of the wingtip group. The latter also played a key role in the recyclability of the catalytic system.

Organometallics published new progress about 597-52-4. 597-52-4 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is Triethylsilanol, and the molecular formula is C6H16OSi, Name: Triethylsilanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Satoh, Yasushi published the artcileHighly selective synthesis of hydrosiloxanes by Au-catalyzed dehydrogenative cross-coupling reaction of silanols with hydrosilanes, Synthetic Route of 597-52-4, the publication is ACS Catalysis (2017), 7(3), 1836-1840, database is CAplus.

We report a highly selective synthesis of siloxane building blocks containing SiH₂or SiH functionalities. The system AuCl(PPh₃)/PPh₃ or AuCl(PPh₃)/PBu₃ catalyzed the reaction of trihydrosilanes with silanols giving SiH₂-containing siloxanes exclusively. On the other hand, a highly selective reaction of dihydrosilanes with silanols to afford SiH-containing siloxanes was achieved by simply changing the phosphine ligand to a bidentate one, xantphos. Usefulness of SiH₂-containing siloxanes was demonstrated by the synthesis of a trisiloxane, Et₃SiOSi(Ph)(H)OSi^tBuMe₂, and a pentasiloxane, Ph₂Si(OSiHPhOSiEt₃)₂, bearing SiH functionalities.

ACS Catalysis published new progress about 597-52-4. 597-52-4 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is Triethylsilanol, and the molecular formula is C6H16OSi, Synthetic Route of 597-52-4.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts