Author: tianli

Meinert, Cornelia published the artcileAnisotropy spectroscopy of chiral alcohols, amines, and monocarboxylic acids: Implications for the analyses of extraterrestrial samples, Recommanded Product: (R)-Oxiran-2-ylmethanol, the publication is Journal of Photochemistry and Photobiology, A: Chemistry (2016), 130-137, database is CAplus.

Stereoisomers of distinct chiral amino acids were observed to occur in L-enantioenriched form in carbonaceous chondrite meteorites. Meteoritic amines and monocarboxylic acids were recently shown to occur in racemic ratio. In this study we investigated the electronic CD and anisotropy spectra of chiral alcs., chiral amines, and chiral monocarboxylic acids. We recorded CD and anisotropy spectra from 280 to 170 nm in aqueous solution using a synchrotron-radiation UV CD spectrophotometer. The obtained anisotropy spectra are employed to discuss the likely role of UV circularly polarized light leading to enantioenriched amino acids, as well as racemic amines and monocarboxylic acids during their primordial interstellar synthesis. These data will moreover accompany the European Space Agency’s Rosetta mission, which successfully landed Philae on the nucleus of comet 67P/Churyumov-Gerasimenko to search for chiral organic mols.

Journal of Photochemistry and Photobiology, A: Chemistry published new progress about 57044-25-4. 57044-25-4 belongs to alcohols-buliding-blocks, auxiliary class Epoxides,Chiral,Aliphatic hydrocarbon chain,Alcohol, name is (R)-Oxiran-2-ylmethanol, and the molecular formula is C3H6O2, Recommanded Product: (R)-Oxiran-2-ylmethanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Bockova, Jana published the artcileChiroptical activity of hydroxycarboxylic acids with implications for the origin of biological homochirality, Synthetic Route of 90-64-2, the publication is Communications Chemistry (2021), 4(1), 86, database is CAplus.

Circularly polarised light (CPL) interacting with interstellar organic mols. might have imparted chiral bias and hence preluded prebiotic evolution of biomol. homochirality. The L-enrichment of extra-terrestrial amino acids in meteorites, as opposed to no detectable excess in monocarboxylic acids and amines, has previously been attributed to their intrinsic interaction with stellar CPL revealed by substantial differences in their chiroptical signals. Recent analyze of meteoritic hydroxycarboxylic acids (HCAs) – potential co-building blocks of ancestral proto-peptides – indicated a chiral bias toward the L-enantiomer of lactic acid. Here we report on novel anisotropy spectra of several HCAs using a synchrotron radiation electronic CD spectrophotometer to support the re-evaluation of chiral biomarkers of extra-terrestrial origin in the context of absolute photochirogenesis. We found that irradiation by CPL which would yield L-excess in amino acids would also yield L-excess in aliphatic chain HCAs, including lactic acid and mandelic acid, in the examined conditions. Only tartaric acid would show “unnatural” D-enrichment, which makes it a suitable target compound for further assessing the relevance of the CPL scenario.

Communications Chemistry published new progress about 90-64-2. 90-64-2 belongs to alcohols-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Alcohol,Natural product, name is 2-Hydroxy-2-phenylacetic acid, and the molecular formula is C8H8O3, Synthetic Route of 90-64-2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Albagli, A. published the artcileRate of ionization of some aromatic hydrocarbons in ethanolic dimethyl sulfoxide, COA of Formula: C19H14O2, the publication is Canadian Journal of Chemistry (1974), 52(7), 1059-61, database is CAplus.

The rates of detritiation of triphenylmethane, 9-phenylxanthene, fluorene, 9-ethylfluorene, 9-phenylfluorene, and 2,3-benzofluorene are measured in ethanolic Me2SO containing NaOEt. When the logarithm of the ionization rate is plotted against the logarithm of the ionization rate of Me2SO a straight line of near-to-unit slope is obtained in each case. There are significant differences, however, between relative ionization rates and equilibrium acidities.

Canadian Journal of Chemistry published new progress about 596-38-3. 596-38-3 belongs to alcohols-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Benzene,Alcohol, name is 9-Phenyl-9H-xanthen-9-ol, and the molecular formula is C19H14O2, COA of Formula: C19H14O2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Lansdown, Kate published the artcileInvestigations into the stable isotope ratios of 1-phenyl-2-propanone, Recommanded Product: 2-Hydroxy-2-phenylacetic acid, the publication is Drug Testing and Analysis (2022), 14(3), 496-504, database is CAplus and MEDLINE.

Stable isotope ratio mass spectrometry (IRMS) can be used to determine the precursor and precursor origin of methylamphetamine drug samples. Previous work has shown that methylamphetamine samples can be distinguished as derived from different sources of (pseudo)ephedrine or phenyl-2-propanone (P2P) through the use of IRMS alongside conventional chem. profiling techniques. To date, limited research has been conducted to investigate whether methylamphetamine samples of differing P2P origins can be distinguished through drug profiling. This was investigated by synthesizing methylamphetamine inhouse in a three-step process. Two ‘preprecursors’ were used in this study, phenylacetic acid (PAA) and α-phenylacetoacetonitrile (α-PAAN). Using a combination of profiling techniques, it was found that methylamphetamine samples of PAA preprecursor origin and methylamphetamine samples of α-PAAN preprecursor origin can be distinguished.

Drug Testing and Analysis published new progress about 90-64-2. 90-64-2 belongs to alcohols-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Alcohol,Natural product, name is 2-Hydroxy-2-phenylacetic acid, and the molecular formula is C8H8O3, Recommanded Product: 2-Hydroxy-2-phenylacetic acid.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Dashti, Amir published the artcileQuantitative structure property relationship schemes for estimation of autoignition temperatures of organic compounds, Synthetic Route of 122-20-3, the publication is Journal of Molecular Liquids (2020), 111797, database is CAplus.

We have extended a quant. structure-property relationship (QSPR) scheme to estimate the auto-ignition temperatures (AIT) of organic compounds by employing GA-ANFIS, PSO-ANFIS, DE-ANFIS and GP methods. The average absolute relative deviations (%AARD) are 7.96, 6.29, 8.85 and 8.26, resp. The range of these values appears to match that of exptl. error in AIT measurements, suggesting strong models. For organic compounds, the AIT can be estimated using the above-mentioned methods, from mol. structure. This goal is possible using only 9 theor. descriptors.

Journal of Molecular Liquids published new progress about 122-20-3. 122-20-3 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment, name is Triisopropanolamine, and the molecular formula is C9H21NO3, Synthetic Route of 122-20-3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Graves, Brian M. published the artcileComprehensive characterization of mainstream marijuana and tobacco smoke, Application of 4-Propylphenol, the publication is Scientific Reports (2020), 10(1), 7160, database is CAplus and MEDLINE.

Recent increases in marijuana use and legalization without adequate knowledge of the risks necessitate the characterization of the billions of nanoparticles contained in each puff of smoke. Tobacco smoke offers a benchmark given that it has been extensively studied. Tobacco and marijuana smoke particles are quant. similar in volatility, shape, d. and number concentration, albeit with differences in size, total mass and chem. composition Particles from marijuana smoke are on average 29% larger in mobility diameter than particles from tobacco smoke and contain 3.4 times more total mass. New measurements of semivolatile fractions determined that >97% of the mass and volume of the particles from either smoke source are comprised of semivolatile compounds For tobacco smoke and marijuana smoke, resp., 4350 and 2575 different compounds are detected, of which 670 and 536 (231 in common) are tentatively identified, and of these, 173 and 110 different compounds (69 in common) are known to cause neg. health effects through carcinogenic, mutagenic, teratogenic, or other toxic mechanisms. This study demonstrates striking similarities between marijuana and tobacco smoke in terms of their phys. and chem. properties.

Scientific Reports published new progress about 645-56-7. 645-56-7 belongs to alcohols-buliding-blocks, auxiliary class Liquid Crystal &OLED Materials, name is 4-Propylphenol, and the molecular formula is C9H12O, Application of 4-Propylphenol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Sguazzin, Matthew A. published the artcileHexafluoroisopropyl Sulfamate: A Useful Reagent for the Synthesis of Sulfamates and Sulfamides, Name: ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, the publication is Organic Letters (2021), 23(9), 3373-3378, database is CAplus and MEDLINE.

Sulfamates and sulfamides were most often synthesized from alcs. and amines with sulfamoyl chloride, which was an unstable reagent. Hexafluoroisopropyl sulfamate (HFIPS) as a bench-stable solid that reacts readily with a wide variety of alcs., amines, phenols, and anilines under mild reaction conditions was identified. The sole byproduct of the reaction was hexafluoroisopropanol (HFIP) and reaction products was often isolated in high purity after an aqueous workup (optional) and removal of solvents by evaporation

Organic Letters published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C15H21BO2, Name: ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Barker, Graeme published the artcileChirality Transfer in Gold(I)-Catalysed Direct Allylic Etherifications of Unactivated Alcohols: Experimental and Computational Study, Safety of 3,3,3-Trifluoropropan-1-ol, the publication is Chemistry – A European Journal (2015), 21(39), 13748-13757, database is CAplus and MEDLINE.

Gold(I)-catalyzed direct allylic etherifications have been successfully carried out with chirality transfer to yield enantioenriched, γ-substituted secondary allylic ethers. Our investigations include a full substrate-scope screen to ascertain substituent effects on the regioselectivity, stereoselectivity and efficiency of chirality transfer, as well as control experiments to elucidate the mechanistic subtleties of the chirality-transfer process. Crucially, addition of mol. sieves was found to be necessary to ensure efficient and general chirality transfer. Computational studies suggest that the efficiency of chirality transfer is linked to the aggregation of the alc. nucleophile around the reactive π-bound Au-allylic ether complex. With a single alc. nucleophile, a high degree of chirality transfer is predicted. However, if three alcs. are present, alternative proton transfer chain mechanisms that erode the efficiency of chirality transfer become competitive.

Chemistry – A European Journal published new progress about 2240-88-2. 2240-88-2 belongs to alcohols-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Aliphatic hydrocarbon chain,Alcohol, name is 3,3,3-Trifluoropropan-1-ol, and the molecular formula is C3H5F3O, Safety of 3,3,3-Trifluoropropan-1-ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Hill, Michael S. published the artcileSingle-source AACVD of composite cobalt-silicon oxide thin films, Category: alcohols-buliding-blocks, the publication is Inorganica Chimica Acta (2014), 47-56, database is CAplus.

A series of cobalt(II) complexes comprising either triorganosiloxide or tris(tert-butoxy)siloxide ligands were synthesized and characterized. A mononuclear constitution is enforced through the incorporation of bi- and tridentate N-donor ligands. The resultant 4- or 6-coordinate complexes were identified by single-crystal x-ray diffraction anal. and were assessed for their potential as mol. precursors to hybrid cobalt/silicon oxide thin film materials by TGA. A TMEDA adduct of the bis-ligated Co(II) tris(tert-butoxy)siloxide species was used as a single-source precursor for the AACVD of aesthetically attractive blue composite films. Anal. by PXRD, SEM, EDS and XPS indicated the production of amorphous, continuous films with the bulk compositions reflecting the cobalt, silicon and oxygen stoichiometry of the mol. precursor complex.

Inorganica Chimica Acta published new progress about 597-52-4. 597-52-4 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is Triethylsilanol, and the molecular formula is C6H16OSi, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Maya, R. J. published the artcileA bentonite-gold nanohybrid as a heterogeneous green catalyst for selective oxidation of silanes, Safety of Triisopropylsilanol, the publication is Chemical Communications (Cambridge, United Kingdom) (2016), 52(70), 10625-10628, database is CAplus and MEDLINE.

A highly efficient, environmentally benign and reusable heterogeneous bentonite-gold nanohybrid catalyst was designed and synthesized. This heterogeneous catalyst could efficaciously catalyze the oxidation of organosilanes to silanols. The reaction is 98.7% atom economical and the products were obtained in excellent yield without the formation of disiloxanes as byproducts. The catalyst was also well applicable for the gram scale preparation of silanols.

Chemical Communications (Cambridge, United Kingdom) published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C9H22OSi, Safety of Triisopropylsilanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts