Author: tianli

Manna, Cesar M. published the artcileStereoselective Catalysis Achieved through in Situ Desymmetrization of an Achiral Iron Catalyst Precursor, Synthetic Route of 597-52-4, the publication is Journal of the American Chemical Society (2015), 137(45), 14232-14235, database is CAplus and MEDLINE.

Stereoselective catalysis proceeds with catalyst control but without the need to synthesize preformed chiral catalysts or ligands. Fe-based catalysts were discovered to effect the stereoselective polymerization of lactides starting from a single achiral precursor and the proper choice of an achiral silanol additive. Spectroscopic anal. of the polymer revealed that the stereoselectivity originates from an enantiomorphic site rather than a chain end stereocontrol mechanism. Fe intermediates that are stereogenic at Fe probably form in situ as a result of desymmetrization that occurs from a change in the metal coordination number The proposed mechanism is supported by a combination of spectroscopic measurements, model complexes, kinetic measurements, and DFT calculations

Journal of the American Chemical Society published new progress about 597-52-4. 597-52-4 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is Triethylsilanol, and the molecular formula is C6H16OSi, Synthetic Route of 597-52-4.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Nishimura, Takahiro published the artcileRhodium-catalyzed aryl transfer from trisubstituted aryl methanols to α,β-unsaturated carbonyl compounds, Recommanded Product: 9-Phenyl-9H-xanthen-9-ol, the publication is Angewandte Chemie, International Edition (2007), 46(26), 4937-4939, database is CAplus and MEDLINE.

The rhodium-catalyzed arylation of α,β-unsaturated carbonyl compounds with 9-aryl-10-benzyl-9,10-dihydroacridin-9-ols as arylating reagents proceeds efficiently via β-aryl elimination of the rhodium alkoxide intermediates, to give the 1,4-addition products in high yields. E.g., reaction of MeCOCH:CHC₅H₁₁ with 9-phenyl-10-benzyl-9,10-dihydroacridin-9-ol gave 96% MeCOCH₂CHPhC₅H₁₁.

Angewandte Chemie, International Edition published new progress about 596-38-3. 596-38-3 belongs to alcohols-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Benzene,Alcohol, name is 9-Phenyl-9H-xanthen-9-ol, and the molecular formula is C19H14O2, Recommanded Product: 9-Phenyl-9H-xanthen-9-ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Matsuda, Yutaka published the artcileSynthetic studies on polymaxenolides: model studies for constructing dihydropyran portion and synthesis of lower portion, HPLC of Formula: 57044-25-4, the publication is Tetrahedron (2014), 70(6), 1154-1168, database is CAplus.

With a goal of the total synthesis of polymaxenolide, the first hybrid marine natural product, the model studies for constructing the dihydropyran portion based on the originally proposed biosynthesis (C-C bond formation followed by dehydrative cyclization) and the synthesis of the lower portion (the C1-C3, C7-C17 portion) based on an iodide-induced Morita-Baylis-Hillman type reaction (a three-component assembly) followed by Suzuki-Miyaura cross-coupling are described.

Tetrahedron published new progress about 57044-25-4. 57044-25-4 belongs to alcohols-buliding-blocks, auxiliary class Epoxides,Chiral,Aliphatic hydrocarbon chain,Alcohol, name is (R)-Oxiran-2-ylmethanol, and the molecular formula is C3H6O2, HPLC of Formula: 57044-25-4.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Kawawaki, Tokuhisa published the artcileCreation of High-Performance Heterogeneous Photocatalysts by Controlling Ligand Desorption and Particle Size of Gold Nanocluster, Name: 2-Phenylethanethiol, the publication is Angewandte Chemie, International Edition (2021), 60(39), 21340-21350, database is CAplus and MEDLINE.

Recently, the creation of new heterogeneous catalysts using the unique electronic/geometric structures of small metal nanoclusters (NCs) has received considerable attention. However, to achieve this, it is extremely important to establish methods to remove the ligands from ligand-protected metal NCs while preventing the aggregation of metal NCs. In this study, the ligand-desorption process during calcination was followed for metal-oxide-supported 2-phenylethanethiolate-protected gold (Au) 25-atom metal NCs using five exptl. techniques. The results clearly demonstrate that the ligand-desorption process consists of ligand dissociation on the surface of the metal NCs, adsorption of the generated compounds on the support and desorption of the compounds from the support, and the temperatures at which these processes occurred were elucidated. Based on the obtained knowledge, we established a method to form a metal-oxide layer on the surface of Au NCs while preventing their aggregation, thereby succeeding in creating a water-splitting photocatalyst with high activity and stability.

Angewandte Chemie, International Edition published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Name: 2-Phenylethanethiol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Hori, Mikio published the artcileDibenzothiepin derivatives and related compounds. III. Investigation of the reactivity of triphenylmethyl hexachloroantimonate and synthesis of 6,11-dihydrodibenzo[b,e]thiepin-11-ylium hexachloroantimonates, Related Products of alcohols-buliding-blocks, the publication is Yakugaku Zasshi (1978), 98(10), 1333-40, database is CAplus and MEDLINE.

In order to exam. the utility of Ph₃CSbCl₆ (I) for organic synthesis, various kinds of hexachloroantimonates of carbonium ions were prepared by the reaction of I with equimolar amounts of various kinds of appropriate cyclic compounds These products were obtained in a simple and stable manner compared to the synthesis of the corresponding perchlorates. Exptl. studies were also made on the limitation of I as an anion (H^–, OH^–, Cl^–, etc.) abstraction reagent, using various kinds of 6,11-dihydrodibenzo[b,e]thiepin derivatives

Yakugaku Zasshi published new progress about 596-38-3. 596-38-3 belongs to alcohols-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Benzene,Alcohol, name is 9-Phenyl-9H-xanthen-9-ol, and the molecular formula is C19H14O2, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Hori, Mikio published the artcileReactivities of heteroaromatic cations containing a group VIB element in nucleophilic reactions. Reactions of 9-phenyl-xanthylium, -thioxanthylium, and -selenoxanthylium salts with amines, sodium phenolate, and sodium benzenethiolate, Synthetic Route of 596-38-3, the publication is Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) (1988), 2271-6, database is CAplus.

Addition of amines RH (R = morpholino, piperidino, NEt₂, 4-MeNHC₆H₄, 4-Me₂NC₆H₄) to 9-phenylchalcogenoxanthylium perchlorates I (X = O, S) gave the expected addition products II (X = O, S; R = same) in 91-98% yields. Addition of PhNH₂ or PhONa to I (X = O, S, Se) gave mixtures of I (X = O, S, Se; R = NHPh, OPh, 4-H₂NC₆H₄, 4-HOC₆H₄) and 1:2 addition products III (X¹ = NH, O). II (R = NHPh) underwent Hofmann-Martius rearrangement to II (R = 4-H₂NC₆H₄). III (X¹ = O) underwent cleavage with HCl to give II (R = OH) and II (R = 4-HOC₆H₄). Addition of PhSNa to I (X = O, S, Se) gave only II (R = SPh).

Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) published new progress about 596-38-3. 596-38-3 belongs to alcohols-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Benzene,Alcohol, name is 9-Phenyl-9H-xanthen-9-ol, and the molecular formula is C19H14O2, Synthetic Route of 596-38-3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Kraetzschmar, Felix published the artcileSelenium-Catalyzed C(sp³)-H Acyloxylation: Application in the Expedient Synthesis of Isobenzofuranones, Name: 4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-ol, the publication is Chemistry – A European Journal (2015), 21(19), 7030-7034, database is CAplus and MEDLINE.

Oxidative Se-catalyzed C(sp³)-H bond acyloxylation has been used to construct a diverse array of isobenzofuranones from simple ortho-allyl benzoic acid derivatives The synthetic procedure employs mild reaction conditions and gives high chemoselectivity enabled by an inexpensive organodiselane catalyst. E.g., in presence of N-fluorobenzenesulfonimide and PhSeSePh, C(sp³)-H acyloxylation of o-allylated benzoic acid (I) gave 81% isobenzofuranone derivative (II). The presented approach offers a new synthetic pathway toward the core structures of phthalide natural products.

Chemistry – A European Journal published new progress about 25240-59-9. 25240-59-9 belongs to alcohols-buliding-blocks, auxiliary class Boronic acid and ester,Boronic Acids,Boronate Esters, name is 4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-ol, and the molecular formula is C6H13BO3, Name: 4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Meininger, Daniel J. published the artcileSynthesis of tetraphenylporphyrinate manganese(III) siloxides by silyl group transfer from silanethiols, SDS of cas: 17877-23-5, the publication is Journal of Coordination Chemistry (2016), 69(11-13), 1970-1978, database is CAplus.

Reaction of [Mn(OAc)(TPP)] (TPP = dianion of meso-tetraphenylporphine) with both HSSiⁱPr₃ and HSSiPh₃ in the presence of air gives the corresponding siloxide complexes, [Mn(OSiR₃)(TPP)] (R = ⁱPr, Ph), via silyl group transfer from S to O. The new compounds were fully characterized in solution and the solid state and represent rare examples of Mn(III) porphyrinates containing Lewis basic axial ligands. X-ray crystallog. analyses of both complexes reveal very short Mn-O bond distances consistent with the presence of a siloxide ligand. Investigations of the reaction pathway are consistent with initial reduction of [Mn(OAc)(TPP)] to [Mn^II(TPP)] by the silanethiol. Subsequent aerobic oxidation of the reaction mixture is proposed to generate a Mn(III) porphyrinate and the corresponding silanol, which combine to yield the observed siloxide complex. These findings stand in sharp contrast to those of iron(III) porphyrinates, where silanethiolate complexes are stable.

Journal of Coordination Chemistry published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C9H22OSi, SDS of cas: 17877-23-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Wojtunik-Kulesza, Karolina published the artcilePreliminary Studies on the Effect of Simulated Digestion on the Antioxidant Activity of Monoterpenes, HPLC of Formula: 106-25-2, the publication is Chemistry & Biodiversity (2022), 19(4), e202100995, database is CAplus and MEDLINE.

One of several possible ways of predicting substance bioactivity under in vivo conditions is through simulated studies based on conditions comparable to those within the organism. Having regards to pH and digestive enzymes, such an approach is through simulated digestion. Simulated studies allow gaining an understanding of physiol. conditions and a prediction of compound behavior. The presented studies are based on simulated digestion (SD) to which selected monoterpenes (γ-terpinene, α-terpinene, α-phellandrene, carvone, menthone, isopulegol, α-pinene, β-pinene, terpinene-4-ol, linalool, eucalyptol, p-cymene, citral, citronellal) have been subjected. The procedure included changes pH (2.0 and 8.5) and digestive enzymes (pepsine in gastric stage and pancreatin in duodenal stage) to better understand what goes on within the gastro-intestinal tract. The changes were observed for gastric and duodenal stages, as well as for two phases: oil and water. Obtained results revealed both pos. and neg. influence of gastrointestinal conditions on monoterpenes antioxidant activity. However, pos. impact prevailed (γ-terpinene, citral, eucalyptol, isopulegol, α-pinene). The differentiation in activity can be explained by solubility in oil/water phases and the biotransformation of studied compounds

Chemistry & Biodiversity published new progress about 106-25-2. 106-25-2 belongs to alcohols-buliding-blocks, auxiliary class Natural product, name is cis-3,7-Dimethyl-2,6-Octadien-1-Ol, and the molecular formula is C6H10F3NO, HPLC of Formula: 106-25-2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Ochowiak, M. published the artcileThe thermostated medical jet nebulizer: Aerosol characteristics, Quality Control of 23828-92-4, the publication is International Journal of Pharmaceutics (Amsterdam, Netherlands) (2019), 118475, database is CAplus and MEDLINE.

The sudden expansion of gas at the outlet of the jet (pneumatic) nebulizer significantly reduces the temperature of the solution, which may provoke bronchospasm, therefore it is recommended to use modern pneumatic inhalers equipped with a thermostat or a universal thermal attachment that allow to obtain a higher temperature aerosol, i.e. thermo-aerosol. The research was carried out for model Newtonian fluids. The droplet diameters of the aerosol spray were investigated using a Spraytec aerosol particle size measurement system. Anal. of the obtained results showed that the increase in solution viscosity caused a decrease in mean droplet diameters and prolonged nebulization time. The anal. of exptl. data made it possible to propose a correlation equation describing the mean diameter of the droplets depending on the properties of the liquid and the flow conditions in the thermostated medical nebulizer. The obtained data contributes to a better understanding of the complex liquid atomization process and can be helpful in the design of medical nebulizers and pharmaceutical preparations

International Journal of Pharmaceutics (Amsterdam, Netherlands) published new progress about 23828-92-4. 23828-92-4 belongs to alcohols-buliding-blocks, auxiliary class Membrane Transporter/Ion Channel,Sodium Channel, name is trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol hydrochloride, and the molecular formula is C13H19Br2ClN2O, Quality Control of 23828-92-4.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts