Author: tianli

Daw, Prosenjit published the artcileSynthesis of Pyrazines and Quinoxalines via Acceptorless Dehydrogenative Coupling Routes Catalyzed by Manganese Pincer Complexes, Safety of 2-Aminobutan-1-ol, the publication is ACS Catalysis (2018), 8(9), 7734-7741, database is CAplus and MEDLINE.

Base-metal catalyzed dehydrogenative self-coupling of 2-amino alcs. to selectively form functionalized 2,5-substituted pyrazine derivatives is presented. Also, 2-substituted quinoxaline derivatives are synthesized by dehydrogenative coupling of 1,2-diaminobenzene and 1,2-diols. In both cases, water and hydrogen gas are formed as the sole byproducts. The reactions are catalyzed by acridine-based pincer complexes of earth-abundant manganese.

ACS Catalysis published new progress about 96-20-8. 96-20-8 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 2-Aminobutan-1-ol, and the molecular formula is C4H11NO, Safety of 2-Aminobutan-1-ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Oleszek, Sylwia published the artcileMitigation of bromine-containing products during pyrolysis of polycarbonate-based tetrabromobisphenol A in the presence of copper(I) oxide, Name: 4-Propylphenol, the publication is Journal of Hazardous Materials (2021), 124972, database is CAplus and MEDLINE.

Polycarbonate (PC) is an engineering thermoplastic that is widely used in elec. and electronic equipment. This plastic often contains tetrabromobisphenol A (TBBA), the most common brominated flame retardant. Thermal degradation of the PC-TBBA leads to generation of numerous bromo-organic products in the pyrolytic oil, hindering its appropriate utilization, as well as corrosive hydrogen bromide gas. The purpose of this study was to exptl. investigate and compare the pyrolysis products of PC-TBBA and PC-TBBA + Cu₂O at various temperatures, with an emphasis on the yield and distribution of brominated compounds In pyrolysis of PC-TBBA + Cu₂O, at the maximum degradation temperature (600 °C), as much as 86% of total Br was trapped in the residue, while 3% and 11% were distributed in the condensate and gas fractions, resp. In contrast, the distribution of Br from non-catalytic pyrolysis of PC-TBBA (600 °C) was 0.5% residue, 40% condensate, and 60% gas. The results of this study revealed that in the presence of Cu₂O, organo-bromine products were most likely involved in Ullman-type coupling reactions, leading to early crosslinking of the polymer network that efficiently hinders their vaporization. HBr in the gas fraction was suppressed due to effective fixation of bromine in residue in the form of CuBr.

Journal of Hazardous Materials published new progress about 645-56-7. 645-56-7 belongs to alcohols-buliding-blocks, auxiliary class Liquid Crystal &OLED Materials, name is 4-Propylphenol, and the molecular formula is C9H12O, Name: 4-Propylphenol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Monton, Chaowalit published the artcileCharacterization of crosslinked hard gelatin capsules for a structural assembly of elementary osmotic pump delivery system, Recommanded Product: trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol hydrochloride, the publication is Journal of Pharmaceutical Investigation (2019), 49(6), 655-665, database is CAplus.

The objective of this study was to characterize the crosslinked hard gelatin capsules (HGCs) for use as a structural assembly of elementary osmotic pumps (EOP). HGCs were crosslinked in formaldehyde vapor for 6, 12, and 24 h. Weight loss after immersing in various mediums, water soluble protein fraction, loss on drying, and formaldehyde residue were investigated. Fourier transform IR (FTIR) spectra were used to detect the crosslinking formation. The EOP capsules were prepared for delivery of diltiazem hydrochloride (DIL HCl) and ambroxol hydrochloride (AMB HCl), which are freely and sparingly water soluble drugs, resp. Physicochem. stability of storage crosslinked HGC shells was investigated. All crosslinked HGC shells were water insoluble FTIR spectra exhibited intermediate lysine methylol and arginine methylol peaks. Storage time increased, moisture content increased and formaldehyde residue decreased. The developing EOP capsules were more appropriate for delivery of high water soluble rather than low water soluble drug. EOP capsule contained 100 mg DIL HCl using HGCs crosslinked for 12 h provided release profiles for 12 h with a lag time of 2.6-3.1 h. It was also found that DIL HCl EOP capsules prepared using crosslinked HGC shells stored for 90 days maintained the similar drug release profiles. AMB HCl EOP capsules exhibited low drug release. In summary, the crosslinked HGCs were applicable as a structural assembly of the osmotic controlled drug delivery system.

Journal of Pharmaceutical Investigation published new progress about 23828-92-4. 23828-92-4 belongs to alcohols-buliding-blocks, auxiliary class Membrane Transporter/Ion Channel,Sodium Channel, name is trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol hydrochloride, and the molecular formula is C13H19Br2ClN2O, Recommanded Product: trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol hydrochloride.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Vaghela, Chetana published the artcileSelective electrochemical sensing of bisphenol derivatives using novel bioelectrode of agarose-guar gum-graphene oxide immobilized with tyrosinase, Category: alcohols-buliding-blocks, the publication is Journal of Environmental Chemical Engineering (2022), 10(3), 107360, database is CAplus.

Bisphenols (BPs) are widely used in manufacturing of recyclable plastic products that are potentially toxic to human beings. In the current investigation, an electrochem. sensor based on a novel bioelectrode of agarose-guar gum-graphene oxide (A-G-GO) immobilized with tyrosinase was developed for bisphenols detection. The sensor was responsive toward six BP derivatives (A, F, E, B, Z and AP) while being non-responsive toward bisphenols S and AF. Formation of A-G-GO composites was confirmed by various anal. techniques. The electrochem. characterization indicated enhanced charge transfer abilities of the composites that helped in improving sensitivity. Mechanism of sensing involved enzymic oxidation of bisphenols to corresponding o-bisphenols and subsequently their reduction on designed bioelectrodes at a potential of 80 mV. The sensor exhibited differential sensitivity toward varied BPs with linear dynamic response in the concentration range of 50-1000 μM and limit of detection ranging from 5 to 50 μM. Based on apparent Km values exhibited by tyrosinase, differential sensitivity toward BPs could be explained. The biosensor was found to be highly selective for bisphenol detection over other tyrosinase substrates with enhanced storage stability of 150 d. The proposed bioelectrode could successfully be used for measurement of bisphenols from plastic food packing material thus demonstrating its practical utility.

Journal of Environmental Chemical Engineering published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C31H25F2N5O7S, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Balandin, A. A. published the artcileCatalytic properties of zirconium phosphate, Formula: C5H11BrO, the publication is Doklady Akademii Nauk SSSR (1965), 161(4), 851-2, database is CAplus.

Catalytic properties of Zr phosphate prepared according to the method described formerly (Amphlett, et al., CA 52, 14281b), were studied. The sp. surface of the catalyst was 335 sq. m./g. and the total acidity 1.2 milliequivalents/g. The kinetics of the dehydration of C₂-C₄ paraffinic alcs. and of cyclohexanol was measured. The conversions at 350-450° were 93-4%. Part of the olefins formed during the dehydration was isomerized. The experiments proved that Zr phosphate is an active catalyst for the reactions, where redistribution of H takes place: isomerization, alkylation, and etherification. Through the changes in preparation of this catalyst it is possible to obtain catalysts of convenient selectivity.

Doklady Akademii Nauk SSSR published new progress about 2588-77-4. 2588-77-4 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is 2-Methyl-3-bromo-2-butanol, and the molecular formula is C5H11BrO, Formula: C5H11BrO.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Buckley, Jessie P. published the artcileExposure to Contemporary and Emerging Chemicals in Commerce among Pregnant Women in the United States: The Environmental influences on Child Health Outcome (ECHO) Program, Application In Synthesis of 80-09-1, the publication is Environmental Science & Technology (2022), 56(10), 6560-6573, database is CAplus and MEDLINE.

Prenatal chem. exposures can influence maternal and child health; however, a few industrial chems. are routinely biomonitored. We assessed an extensive panel of contemporary and emerging chems. in 171 pregnant women across the United States (U.S.) and Puerto Rico in the Environmental influences on Child Health Outcome (ECHO) Program. We simultaneously measured urinary concentrations of 89 analytes (103 total chems. representing 73 parent compounds) in nine chem. groups: bactericides, benzophenones, bisphenols, fungicides and herbicides, insecticides, organophosphate esters (OPEs), parabens, phthalates/alternative plasticizers, and polycyclic aromatic hydrocarbons (PAHs). We estimated associations of creatinine-adjusted concentrations with sociodemog. and specimen characteristics. Among our diverse prenatal population (60% non-Hispanic Black or Hispanic), we detected 73 of 89 analytes in � participant and 36 in >50% of participants. Five analytes not currently included in the U.S. biomonitoring were detected in �0% of samples: benzophenone-1, thiamethoxam, mono-2-(propyl-6-carboxy-hexyl) phthalate, monocarboxy isooctyl phthalate, and monohydroxy-iso-decyl phthalate. Many analyte concentrations were higher among individuals of Hispanic ethnicity compared to those of non-Hispanic White women. Concentrations of certain chems. decreased with the calendar year, whereas concentrations of their replacements increased. Our largest study to date identified widespread exposures to prevalent and understudied chems. in a diverse sample of pregnant women in the U. S.

Environmental Science & Technology published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C12H10O4S, Application In Synthesis of 80-09-1.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Kazmierczak, Joanna published the artcileRu-Catalyzed Dehydrogenative Silylation of POSS-Silanols with Hydrosilanes: Its Introduction to One-Pot Synthesis, Category: alcohols-buliding-blocks, the publication is Inorganic Chemistry (2019), 58(2), 1201-1207, database is CAplus and MEDLINE.

A com. available and stable ruthenium dodecacarbonyl catalyst Ru₃(CO)₁₂ allows very efficient and convenient access to functionalized silsesquioxanes (SQs) containing siloxane moiety (Si-O-Si) via dehydrogenative coupling of POSS-silanols with hydrosilanes. With the aid of SiH-containing silsesquioxanes, an unprecedented one-pot procedure has been revealed, and the usefulness of this approach was demonstrated by the synthesis of various derivatives via O-silylation, as well as C:C and C:N hydrosilylation.

Inorganic Chemistry published new progress about 597-52-4. 597-52-4 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is Triethylsilanol, and the molecular formula is C6H16OSi, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Kazmierczak, Joanna published the artcileIntroduction of Boron Functionalities into Silsesquioxanes: Novel Independent Methodologies, Product Details of C9H22OSi, the publication is Chemistry – A European Journal (2018), 24(10), 2509-2514, database is CAplus and MEDLINE.

Owing to their versatile application possibilities, silsesquioxanes (SQs) are of considerable interest for creating hybrid inorganic-organic materials. In this report, two novel and independent strategies for the direct attachment of boron functionalities to silsesquioxanes are presented. Encouraged by our previous work concerning the synthesis of borasiloxanes through the catalyst-free dehydrogenative coupling of silanols and boranes, we decided to apply our method to a synthesis of various boron-functionalized silsesquioxanes. During our tests, we also investigated the activity of scandium(III) triflate, which we have previously used as an excellent catalyst for the obtaining of Si-O-Si and Si-O-Ge moieties. As a result, we also discovered a novel approach for the O-borylation of Si-OH groups in silsesquioxanes with allylborane. Both routes are highly chemoselective and efficiently lead to the obtaining of Si-O-B moiety under air atm. and at room temperature

Chemistry – A European Journal published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C9H22OSi, Product Details of C9H22OSi.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Shimizu, Ken-ichi published the artcileSurface Oxygen-Assisted Pd Nanoparticle Catalysis for Selective Oxidation of Silanes to Silanols, SDS of cas: 597-52-4, the publication is Chemistry – A European Journal (2012), 18(8), 2226-2229, S2226/1-S2226/12, database is CAplus and MEDLINE.

Oxygen-adsorbed Pd surfaces show higher reactivity for water dissociation than clean Pd surfaces. Thus, carbon-supported Pd nanoparticles with surface oxygen atoms show higher activity for hydrolytic oxidation of silanes than previously reported catalysts. The synthetic utility of this catalyst is quite high because the catalyst, readily prepared from com. Pd/C, is easily recovered and reused, and shows high activity in oxidation of various silanes. This is a surface-science driven strategy of catalyst design for green organic synthesis. E.g., hydration of Et₃SiH in presence of carbon-supported Pd nanoparticles covered with O gave >99% Et₃SiOH, with TON = 20,000.

Chemistry – A European Journal published new progress about 597-52-4. 597-52-4 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is Triethylsilanol, and the molecular formula is C4HN5, SDS of cas: 597-52-4.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Shimizu, Ken-ichi published the artcileSurface Oxygen-Assisted Pd Nanoparticle Catalysis for Selective Oxidation of Silanes to Silanols, Computed Properties of 17877-23-5, the publication is Chemistry – A European Journal (2012), 18(8), 2226-2229, S2226/1-S2226/12, database is CAplus and MEDLINE.

Oxygen-adsorbed Pd surfaces show higher reactivity for water dissociation than clean Pd surfaces. Thus, carbon-supported Pd nanoparticles with surface oxygen atoms show higher activity for hydrolytic oxidation of silanes than previously reported catalysts. The synthetic utility of this catalyst is quite high because the catalyst, readily prepared from com. Pd/C, is easily recovered and reused, and shows high activity in oxidation of various silanes. This is a surface-science driven strategy of catalyst design for green organic synthesis. E.g., hydration of Et₃SiH in presence of carbon-supported Pd nanoparticles covered with O gave >99% Et₃SiOH, with TON = 20,000.

Chemistry – A European Journal published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C48H47FeP, Computed Properties of 17877-23-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts