Author: tianli

Wu, Rui published the artcileCopper-catalyzed aerobic oxidative dehydrogenative ring-opening reaction of glycine esters with α’-angelicalactone: Approach to construct α-amino-γ-ketopimelates, HPLC of Formula: 20880-92-6, the publication is Advanced Synthesis & Catalysis (2019), 361(14), 3436-3440, database is CAplus.

A copper-catalyzed aerobic oxidative dehydrogenative reaction of glycine derivatives with α’-angelicalactone is achieved under mild and simple reaction conditions. This strategy can be applicable to a wide range of glycine esters, including complex substrates derived from (+)-dehydroisoandrosterone or menthol, thus enabling the oxidative dehydrogenative ring-opening reaction for producing diverse functionalized α-amino-γ-ketopimelate derivatives in an atom-economic manner.

Advanced Synthesis & Catalysis published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C20H18BrN3, HPLC of Formula: 20880-92-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Wang, Chao published the artcileSalting-out re-distillation combined with sensory-directed analysis to recover odor-active compounds for improving the flavor quality of instant Pu-erh tea, HPLC of Formula: 106-25-2, the publication is Food Chemistry: X (2022), 100310, database is CAplus and MEDLINE.

The objective of this study was to develop an effective recovery technol. of odor-active compounds (OACs) to improve the flavor quality of instant Pu-erh tea (IPT) based on their released behaviors. Salting-out re-distillation (SRD) combined with sensory-directed anal. was developed. The contributing factors, including the soaking time of tea, recovery volume of condensed water of first distillation, amount of sodium chloride, recovery volume of condensed water of SRD, and re-use times of sodium chloride, were studied systematically. Under optimized conditions, 41 OACs were recovered in the first distillation, and the total recovery rate was 83.94%. Forty-one OACs were recovered via SRD, and the total recovery rate reached 72.29%, significantly better than membrane method (33.46%). The IPT prepared by adding OACs that recovered via SRD showed strong aroma attributes intensities and good coordination. This developed method can provide a more effective scheme to improve the flavor quality of IPT.

Food Chemistry: X published new progress about 106-25-2. 106-25-2 belongs to alcohols-buliding-blocks, auxiliary class Natural product, name is cis-3,7-Dimethyl-2,6-Octadien-1-Ol, and the molecular formula is C12H13F2N3O4S, HPLC of Formula: 106-25-2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Feng, Fan published the artcileDesign, Ultrasonic-assisted Synthesis and Evaluation In vitro Antimicrobial Activity of Bis-isoxazole Derivatives Bearing Chloro-pyridinyl Group, Computed Properties of 438565-33-4, the publication is Chemical Research in Chinese Universities (2021), 37(3), 668-673, database is CAplus.

An ultrasonic-assisted synthesis of bis-isoxazole derivatives was developed. Eight 3-(6-chloropyridin-3-yl)-5-{[(3-arylisoxazol-5-yl)methoxy]methyl}isoxazoles I [R¹ = H, 4-Me, 2-Cl, etc.] were synthesized by 1,3-dipolar cycloaddition reaction between substituted isoxazolyl alkyne compounds and 6-chloro-N-hydroxynicotinimidoyl chloride. The structures of the synthesized compounds were confirmed by HRMS, FTIR, ¹H and ¹³C NMR spectroscopy. Wherein, the antifungal and antibacterial activities of target compounds were tested. The synthesized compounds I [R¹ = 2-methoxy, 2-Cl] exhibited better antifungal activity in comparison with the standard drug itraconazole. The min. inhibitory concentrations(MICs) of compound I [R¹ = 2-methoxy, 2-Cl] were both 4μg/mL against Candida albicans ATCC 10231.

Chemical Research in Chinese Universities published new progress about 438565-33-4. 438565-33-4 belongs to alcohols-buliding-blocks, auxiliary class Isoxazole,Chloride,Benzene,Alcohol, name is 3-(2-Chlorophenyl)-5-isoxazolemethanol, and the molecular formula is C10H8ClNO2, Computed Properties of 438565-33-4.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Su, De-Quan published the artcileClinical Analysis of 122 Cases with Mycoplasma Pneumonia Complicated with Atelectasis: A Retrospective Study, Name: trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol hydrochloride, the publication is Advances in Therapy (2020), 37(1), 265-271, database is CAplus and MEDLINE.

Introduction: This study aims to explore the clin. characteristics, treatment, and prognosis of mycoplasma pneumonia complicated with atelectasis. Methods: A retrospective anal. was performed on 122 children with mycoplasma pneumonia complicated with atelectasis. These children were hospitalized in the Xiamen Campus of the Pediatric Hospital of Fudan University and the Children’s Hospital of Xiamen between Dec. 2015 and Dec. 2018. A diagnosis was made for each case on the basis of the clin. symptoms and signs, Mycoplasma pneumoniae-specific IgM antibody, and imaging results. Results: Among the 122 cases with mycoplasma pneumonia complicated with atelectasis, all cases had retractable M. pneumoniae infection, 102 cases underwent fibrobronchoscopic lavage treatment, and all cases were treated with macrolide antibiotics after a definite diagnosis was made. Furthermore, 107 cases improved and were discharged. Follow-up was performed for 3-4 wk for all patients, and all patients, including the five cases with retractable disease, recovered well. Conclusion: The major clin. manifestations for M. pneumoniae pneumonia are fever and stimulatory dry cough. Macrolide antibiotics remain the treatment of choice.

Advances in Therapy published new progress about 23828-92-4. 23828-92-4 belongs to alcohols-buliding-blocks, auxiliary class Membrane Transporter/Ion Channel,Sodium Channel, name is trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol hydrochloride, and the molecular formula is C12H9NO, Name: trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol hydrochloride.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Cheng, Can published the artcileThe absorption of SO₂ by morpholine cyclic amines with sulfolane as the solvent for flue gas, Formula: C6H13NO2, the publication is Journal of Hazardous Materials (2021), 124462, database is CAplus and MEDLINE.

The absorption properties of N-(2-hydroxyethyl) morpholine (HEM), morpholine (MP) and N-(2-aminoethyl) morpholine (AEM) for SO₂ were studied using sulfolane (SUL) as solvent in this work. Among these solvent combinations, HEM/SUL shows the best cyclic absorption performance, and the capacity of HEM-SUL-40 (40 wt% of HEM and 60 wt% of SUL) to absorb 8580 mg/m³ SO₂ (the remainder is N₂) is 192.18 mg/g at 293.15 K. The absorption capacity of the second cycle is 97.5% of the first absorption cycle, which is higher than 70% of the Cansolv amine solution in a com. application with similar exptl. conditions. However, MP/SUL is difficult to desorb at high temperature, and the absorption capacity of AEM/SUL is much lower than HEM/SUL and MP/SUL. According to the FTIR, ¹H NMR and ¹³C NMR, all three cyclic amines have charge transfer effects with SO₂. The structure of HEM/SUL can be recovered after heating, but MP cannot be recovered. Δ_rG_m° in the reaction against HEM with SO₂ increases significantly with increasing temperature The Δ_rG_m° of HEM-SO₂ and MP-SO₂ at 353.15 K is -12.56 kJ/mol and -16.29 kJ/mol, resp., which further explains the easy desorption of HEM-SO₂ and the difficult desorption of MP-SO₂ at high temperaturesulfur dioxide morpholine cyclic amine sulfolane solvent flue gas.

Journal of Hazardous Materials published new progress about 622-40-2. 622-40-2 belongs to alcohols-buliding-blocks, auxiliary class Morpholine,Alcohol, name is 2-Morpholinoethanol, and the molecular formula is C6H13NO2, Formula: C6H13NO2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Niu, Lijun published the artcileTuning the reactivity of permanganate by naturally occurring DNA bases: Enhanced efficiency of micropollutant abatement, Application In Synthesis of 80-09-1, the publication is Separation and Purification Technology (2022), 120654, database is CAplus.

The transformation of extracellular DNA (e.g., antibiotic resistance genes) in water has attracted increasing attention over the last decades. To date, the effect of the resulting byproducts (e.g., DNA bases) on the degradation of micropollutants by oxidants remains largely unknown. In this study, four DNA bases (i.e., deoxyadenosine (dA), deoxythymidine (dT), deoxycytidine (dC), and deoxyguanosine (dG)) were investigated as potential permanganate (Mn(VII)) activators for the oxidation of tetracycline (TC) in water. The dC exhibited the best performance, e.g., the first-order rate constant of TC increased from 0.082 min-1 in the absence of dC (i.e., Mn(VII) alone) to 0.290 min^-1 in the presence of 500μM dC (i.e., Mn(VII)/dC system). The degradation of three other emerging micopollutants (i.e., bisphenol F (BPF), bisphenol S (BPS), and methotrexate (MTX)) by Mn(VII)/dC was also greater than Mn(VII) alone. Multiple lines of evidence suggested that the synergistic effect of in-situ formed MnO2 colloids and Mn(VII) had a major role in the observed enhancement compared to radicals, Mn(VI), Mn(V) or Mn(III). The transformation products (TPs) of TC by Mn(VII) with and without dC were tentatively identified, from which the reaction pathways were proposed. Despite the high degradation of micropollutants by Mn(VII)/dC system, the majority of TPs were recalcitrant to biodegradation with multi-endpoint adverse health effects on different aquatic organisms, as indicated by in silico prediction software. Overall, this study unveiled the free DNA bases as in-situ Mn(VII) activators for removing emerging contaminants of global concern from water. However, the secondary environmental risks related to the TPs need to be considered in terms of water safety assessment.

Separation and Purification Technology published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C12H10O4S, Application In Synthesis of 80-09-1.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Wang, Yixuan published the artcileWidely targeted metabolomics analysis of enriched secondary metabolites and determination of their corresponding antioxidant activities in Elaeagnus angustifolia var. orientalis (L.)Kuntze fruit juice enhanced by Bifidobacterium animalis subsp. Lactis HN-3 fermentation, Quality Control of 621-37-4, the publication is Food Chemistry (2022), 131568, database is CAplus and MEDLINE.

Elaeagnus angustifolia var. orientalis (L.)Kuntze fruit contains a large number of naturally occurring mols. present as glycoside, methylated, and Me ester conjugates, which should be hydolyzed or transformed to become bioactive forms. For this purpose, Bifidobacterium animalis subsp. lactis HN-3 was selected to ferment Elaeagnus angustifolia var. orientalis (L.)Kuntze fruit juice (EOJ). After fermentation, the total phenolic content (TPC) and antioxidant capacity of the EOJ increased significantly compared to the non-fermented EOJ. Using widely-targeted metabolomics anal., polyphenolic compounds involved in the flavonoid biosynthetic pathway were determined to be up-regulated in the fermented EOJ. In addition, the metabolites generated by 8 deglycosidation, 5 demethylation, 5 hydrogenation, and 28 other reactions were detected in higher concentrations in the fermented EOJ compared to the non-fermented EOJ. Interestingly, these up-regulated metabolites have higher antioxidant and other biol. activities than their metabolic precursors, which provide a theor. basis for the development of Bifidobacterium-fermented plant products with stronger functional activities.

Food Chemistry published new progress about 621-37-4. 621-37-4 belongs to alcohols-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Phenol,Natural product, name is 3-Hydroxyphenylacetic acid, and the molecular formula is C27H39ClN2, Quality Control of 621-37-4.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Liang, Xinjie published the artcileCopper and L-(-)-quebrachitol catalyzed hydroxylation and amination of aryl halides under air, Quality Control of 621-37-4, the publication is Tetrahedron Letters (2020), 61(33), 152222, database is CAplus.

L-(-)-Quebrachitol, a natural product obtained from waste water of the rubber industry, was utilized as an efficient ligand for the copper-catalyzed hydroxylation and amination of aryl halides to selectively give phenols and aryl amines in water or 95% ethanol. In addition, the hydroxylation of 2-chloro-4-hydroxybenzoic acid was validated on a 100-g scale under air.

Tetrahedron Letters published new progress about 621-37-4. 621-37-4 belongs to alcohols-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Phenol,Natural product, name is 3-Hydroxyphenylacetic acid, and the molecular formula is C8H8O3, Quality Control of 621-37-4.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Dai, Hongjun published the artcileAnalysis on the degradation of organic pollutants in textile wastewater treatment process by GC-MS, COA of Formula: C9H22OSi, the publication is Zhejiang Daxue Xuebao, Lixueban (2014), 41(1), 72-77, database is CAplus.

Textile wastewater is intractable industrial wastewater because of its big quantity and high concentration of complicated constituents. The research object was the wastewater from each unit of a sewage treatment plant in Zhejiang province, and gas chromatog.-mass spectrometry(GC-MS) was used to determine the degradation process of organic pollutants in treatment processes. The results show that wastewater samples from the primary settling tank, the secondary sedimentation tank and the final settling tank resp. contained 50, 40 and 30 kinds of organic matters, including chloroform, 1, 2-dichloroethane, 1, 1, 2-trichloroethane and other eight kinds of organic matters which belong to environmental priority control contaminants. Acetophenone, chloroform, 2-chloro-2-Me butane and other five kinds of organic matters are chosen as the characteristic pollutants in textile wastewater. The research has important significance on the treatment and reuse of textile wastewater.

Zhejiang Daxue Xuebao, Lixueban published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C9H22OSi, COA of Formula: C9H22OSi.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Liu, Huifang published the artcilePhotocatalytic Cleavage of C-C Bond in Lignin Models under Visible Light on Mesoporous Graphitic Carbon Nitride through π-π Stacking Interaction, Related Products of alcohols-buliding-blocks, the publication is ACS Catalysis (2018), 8(6), 4761-4771, database is CAplus.

Photocatalysis is a potentially promising approach to harvest aromatic compounds from lignin. However, the development of an active and selective solid photocatalyst is still challenging for lignin transformation under ambient conditions. We herein report a mild photocatalytic oxidative strategy for C-C bond cleavage of lignin β-O-4 and β-1 linkages using a mesoporous graphitic carbon nitride catalyst. Identifications by solid-state NMR techniques and d. functional theory (DFT) calculations indicate that π-π stacking interactions are most likely present between the flexible carbon nitride surface and lignin model mol. Besides, low charge recombination efficiency and high sp. surface area (206.5 m² g^-1) of the catalyst also contribute to its high catalytic activity. Mechanistic investigations reveal that photogenerated holes, as the main active species, trigger the oxidation and C-C bond cleavage of lignin models. This study sheds light on the interaction between complex lignin structures and the catalyst surface and provides a new strategy of photocatalytic cleavage of lignin models with heterogeneous photocatalysts.

ACS Catalysis published new progress about 70110-65-5. 70110-65-5 belongs to alcohols-buliding-blocks, auxiliary class Benzene,Alcohol,Ether,Benzene Compounds, name is 2-Phenoxy-1-phenylpropane-1,3-diol, and the molecular formula is C15H16O3, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts