Author: tianli

Wang, Cheng published the artcileIdentifying Key Metabolites Associated with Glucosinolate Biosynthesis in Response to Nitrogen Management Strategies in Two Rapeseed (Brassica napus) Varieties, Application In Synthesis of 90-64-2, the publication is Journal of Agricultural and Food Chemistry (2022), 70(2), 634-645, database is CAplus and MEDLINE.

A high glucosinolate (GSL) concentration, an undesirable substance, has severely restricted rapeseed (Brassica species) development. We performed widely targeted metabolomics anal. based on the ultra-high-performance liquid chromatog.-electrospray ionization-tandem mass spectrometry (UPLC-ESI-MS/MS) technol. to analyze the metabolic profiles and identify the differential metabolites and GSL components in response to different nitrogen (N) levels in two rapeseed varieties. A total of 341 metabolites and 38 GSL components were detected in the seeds. A total of 188 differential metabolites, including 34 GSL components, were identified in response to different treatments, which were mapped into 2-oxocarboxylic acid metabolism, tryptophan metabolism, and GSL biosynthesis. Key indicators of GSL components highly responsible for different N levels under two contrasting varieties were recognized, i.e., 1-methylpropyl GSL and 4-methylthiobutyl GSL. This study suggests that the efficient N management and variety selection are important strategies for developing rapeseed with low GSLs.

Journal of Agricultural and Food Chemistry published new progress about 90-64-2. 90-64-2 belongs to alcohols-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Alcohol,Natural product, name is 2-Hydroxy-2-phenylacetic acid, and the molecular formula is C4H5NS2, Application In Synthesis of 90-64-2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Li, Yaowen published the artcileNovel low-bandgap oligothiophene-based donor-acceptor alternating conjugated copolymers: synthesis, properties, and photovoltaic applications, Related Products of alcohols-buliding-blocks, the publication is Journal of Polymer Science, Part A: Polymer Chemistry (2010), 48(13), 2765-2776, database is CAplus.

A series of novel soluble donor-acceptor low-bandgap-conjugated polymers consisting of different oligothiophene (OTh) coupled to electron-accepting moiety 2-pyran-4-ylidenemalononitrile (PM)-based unit were synthesized by Stille or Suzuki coupling polymerization The combination of electron-accepting PM building block with varied OTh_n (the number of thiophene unit increases from 3 to 5) results in enhanced π-π stacking in solid state and intramol. charge transfer (ICT) transition, which lead to an extension of the absorption spectra of the copolymers. Cyclic voltammetry measurements and MO distribution calculations indicate that the highest occupied MOs (HOMO) energy levels could be fine-tuned by changing the number of thiophene units of the copolymers, and the resulting copolymers possessed relatively low HOMO energy levels promising good air stability and high-open circuit voltage (V_oc) for photovoltaic application. Bulk heterojunction photovoltaic devices were fabricated by using the copolymers as donors and (6,6)-Ph C₆₁-butyric acid Me ester as acceptor. The highest V_oc reached 0.94 V, and the short circuit currents (J_sc) were improved from 1.78 to 2.54 mA/cm², though the power conversion efficiencies of the devices were measured between 0.61 and 0.99% under simulated AM 1.5 solar irradiation of 100 mW/cm², which indicated that this series copolymers can be promising candidates for the photovoltaic applications.

Journal of Polymer Science, Part A: Polymer Chemistry published new progress about 239075-02-6. 239075-02-6 belongs to alcohols-buliding-blocks, auxiliary class Thiophene,Boronic acid and ester,Boronate Esters, name is 5,5′-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,2′-bithiophene, and the molecular formula is C20H28B2O4S2, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Li, Xiaowei published the artcileNickel-Catalyzed Arylation of C(sp³)-O Bonds in Allylic Alkyl Ethers with Organoboron Compounds, Recommanded Product: ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, the publication is Organic Letters (2021), 23(17), 6612-6616, database is CAplus and MEDLINE.

A nickel-catalyzed cross-coupling of allylic alkyl ethers with organoboron compounds through the cleavage of the inert C(sp³)-O(alkyl) bonds is described. Several types of allylic alkyl ethers can be coupled with various boronic acids or their derivatives to give the corresponding products in good to excellent yields with wide functional group tolerance and excellent regioselectivity. The gram-scale reaction and late-stage modification of biol. active compounds further prove the practicality of this synthetic method.

Organic Letters published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C12H20O6, Recommanded Product: ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zhou, Pan published the artcileMolybdenum-Catalyzed Cross-Coupling of Benzyl Alcohols: Direct C-OH Bond Transformation via [2 + 2]-Type Addition and Elimination, Product Details of C19H14O2, the publication is Organic Letters (2022), 24(23), 4218-4223, database is CAplus and MEDLINE.

Traditional cross-couplings catalyzed by transition metal catalysts generally rely on the classic oxidative addition-transmetalation-reductive elimination process, which requires low-valent precious metals and an inert atm. and which initiates from carbon-alide or pesudo carbon-halide bonds. Herein, an unprecedented molybdenum-oxo-complex-catalyzed intermol. cross-coupling of benzyl alcs. has been reported. Various alcs. including primary, secondary, and tertiary substrates can proceed efficiently under these conditions. Several functional groups sensitive to the low-valent transition metals, such as aryl halides, can be well tolerated. The mechanistic studies and DFT calculations suggest that an intramol. concerted cyclization was involved in the reverse [2 + 2]-type elimination process.

Organic Letters published new progress about 596-38-3. 596-38-3 belongs to alcohols-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Benzene,Alcohol, name is 9-Phenyl-9H-xanthen-9-ol, and the molecular formula is C10H14O, Product Details of C19H14O2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Cao, Zhi published the artcileTotal Synthesis of Two Pyrrole Spiroketal Alkaloids: Pollenopyrroside A and Capparisine B, Name: ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, the publication is Synlett (2015), 26(7), 921-926, database is CAplus.

Pollenopyrroside A (I) and capparisine B (II), two diastereoisomers of pyrrole spiroketal alkaloids isolated from Brassica campestris pollen and Capparis spinosa, were synthesized by an improved microwave-assisted bishydroxymethylation of pyrrole and acid-catalyzed spirocyclization as key steps with total yields of 2.7 and 8.8%, resp.

Synlett published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C12H20O6, Name: ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Wang, Gang published the artcileLiquid-Phase Epoxidation of Propylene with H₂O₂ over TS-1 Zeolite: Impurity Formation and Inhibition Study, Safety of 2-Aminobutan-1-ol, the publication is Industrial & Engineering Chemistry Research (2021), 60(32), 12109-12122, database is CAplus.

The liquid-phase epoxidation of propylene with H₂O₂ over titanium silicalite-1 (TS-1) zeolite was investigated in detail with a focus on the formation and inhibition of various trace impurities like acetaldehyde, propionaldehyde, acetone, hydroxyacetone, acetals, esters, etc. The results showed that the formation of trace impurities involved the transformation of propylene oxide (PO), its oxidation/isomerization/ring-opening (solvolysis and hydrolysis) byproducts, methanol solvent, and even propylene. Roughly speaking, the epoxidation conditions, viz., low temperature, short residence time, and slightly alk. reaction medium, that are beneficial to suppress the ring-opening byproducts of PO, were seen facilitating the inhibition of trace impurities as well. To lower the trace impurities via modification of the TS-1 catalyst, the hydrothermal modification of TS-1 with organic amines such as amino-2-propanol (MIPA) was attempted and its effectiveness was demonstrated. The TS-1 zeolite suitably modified by MIPA exhibited abundant Ti-OH groups (3672 cm^-1) together with remarkably decreased PO adsorption.

Industrial & Engineering Chemistry Research published new progress about 96-20-8. 96-20-8 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 2-Aminobutan-1-ol, and the molecular formula is C5H10O, Safety of 2-Aminobutan-1-ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Wang, Xinglin published the artcileEfficient visible light initiated hydrothiolations of alkenes/alkynes over Ir₂S₃/ZnIn₂S₄: Role of Ir₂S₃, Name: 2-Phenylethanethiol, the publication is Chinese Journal of Catalysis (2021), 42(3), 409-416, database is CAplus.

The hydrothiolations of alkynes/alkenes with thiols is an atom-economic and thus attractive method for the constructions of C-S bonds. Here, Ir₂S₃/ZnIn₂S₄ nanocomposites with varied Ir₂S₃ loadings were obtained by one-pot solvothermal method from ZnCl₂, InCl₃ and thioacetamide with IrCl₃. The loading of Ir₂S₃ on the surface of ZnIn₂S₄ promoted the hydrothiolations of alkenes and alkynes, with an optimum performance observed over 0.5 mol% Ir₂S₃/ZnIn₂S₄ nanocomposite. Based on the studies on the performance of several other cocatalysts (MoS₂, NiS and Pd) loaded ZnIn₂S₄ and the EIS analyses, it was proposed that the superior performance over Ir₂S₃/ZnIn₂S₄ nanocomposite can be ascribed to an improved efficiency on the photogeneration of the thiyl radicals by loading Ir₂S₃ as well as its inactivity for photocatalytic hydrogen evolution, a side reaction in the light-initiated hydrothiolation reaction over ZnIn₂S₄. This study not only demonstrates an efficient and green strategy to synthesize thiolated products under visible light based on semiconductor photocatalysis, but also provides some guidance for the design and development of photocatalytic systems for light-induced organic syntheses.

Chinese Journal of Catalysis published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C12H14BNO2, Name: 2-Phenylethanethiol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

He, Xuefeng published the artcileHighly efficient synthesis of benzodioxins with a 2-site quaternary carbon structure by secondary amine-catalyzed dual Michael cascade reactions, Name: 2-Hydroxy-4-(trifluoromethyl)benzoic acid, the publication is Organic & Biomolecular Chemistry (2018), 16(30), 5533-5538, database is CAplus and MEDLINE.

Salicylic acids and substituted ynones were employed as substrates to afford a class of valuable 4H-benzo[d][1,3]dioxin-4-ones with a 2-site quaternary carbon structure in up to 92% yield by secondary amine-catalyzed dual Michael cascade reactions under mild reaction conditions. The α,β-unsaturated ketone as the key intermediate in the cascade process was successfully separated and characterized. As a result, a new reaction route for ynone species is demonstrated, which is totally different from the existing allenamine activation model.

Organic & Biomolecular Chemistry published new progress about 328-90-5. 328-90-5 belongs to alcohols-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Carboxylic acid,Benzene,Phenol, name is 2-Hydroxy-4-(trifluoromethyl)benzoic acid, and the molecular formula is C8H5F3O3, Name: 2-Hydroxy-4-(trifluoromethyl)benzoic acid.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Yang, Cai-hong published the artcileAnalysis of clinical efficacy and safety of carboprost tromethamine combined with Barkri balloon in treatment of postpartum hemorrhage, Application In Synthesis of 58551-69-2, the publication is Xiandai Zhenduan Yu Zhiliao (2017), 28(16), 3003-3005, database is CAplus.

To explore the clin. efficacy and safety of carboprost tromethamine combined with Barkri balloon in the treatment of postpartum hemorrhage. A total of 90 patients with postpartum hemorrhage admitted to our hospital from Jan. 2015 to Dec. 2016 were selected and randomly divided into a control group and an observation group with 45 cases each. In the control group, a Bakri balloon was injected from the vagina or uterine incision during cesarean section, and 300mL of normal saline was injected. Patients in the observation group were injected with carboprost tromethamine for combination therapy on the basis of the control group. Both groups of patients were treated for 24 h. The clin. efficacy of the two groups of patients was compared, systolic blood pressure (SBP), diastolic blood pressure (DBP) and blood oxygen saturation (SaO₂), blood loss and adverse reactions were compared for safety evaluation of the combination. Results: After treatment, the total effective rates of the observation group and the control group were 93.33% and 80.00%, resp., and there was a statistical difference between the two groups (P < 0.05). There was no statistical difference in the amount of bleeding before treatment between the two groups of patients with postpartum hemorrhage (P > 0.05). After 2h and 24h of hemostatic treatment, the bleeding volume of the observation group was significantly less than that of the control group (P < 0.05). There was no significant difference in SBP, DBP and SaO₂ between the two groups of patients with postpartum hemorrhage before and after treatment (P > 0.05). There was no significant difference in the occurrence of adverse reactions between the two groups (P > 0.05). There was no statistically significant difference in the incidence of adverse reactions between the two groups. Carprost tromethamine combined with Bakri balloon has good clin. efficacy and high safety in the treatment of postpartum hemorrhage, and it is worthy of clin. application.

Xiandai Zhenduan Yu Zhiliao published new progress about 58551-69-2. 58551-69-2 belongs to alcohols-buliding-blocks, auxiliary class Chiral,Alkenyl,Amine,Aliphatic cyclic hydrocarbon,Ester,Alcohol,Inhibitor,, name is 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid, and the molecular formula is C26H41N5O7S, Application In Synthesis of 58551-69-2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Liu, Zhongyu published the artcileObservation of Core Phonon in Electron-Phonon Coupling in Au₂₅ Nanoclusters, Name: 2-Phenylethanethiol, the publication is Journal of Physical Chemistry Letters (2021), 12(6), 1690-1695, database is CAplus and MEDLINE.

Temperature-dependent optical properties are of paramount importance for fundamentally understanding the electron-phonon interactions and phonon modes in atomically precise nanocluster materials. In this work, low-temperature optical absorption spectra of the icosahedral [Au₂₅(SR)₁₈]^– nanocluster are measured from room temperature down to liquid helium temperature by adopting a thin-film-based technique. The thin-film measurement is further compared with results from the previous solution-based method. Interestingly, the previously missing core phonon is revealed by a quant. anal. of the film data through peak deconvolution and fitting of the temperature trend with a theor. model. The two lowest-energy absorption peaks (at 1.6 and 1.8 eV) of Au₂₅ are determined to couple with the staple-shell phonon (average energy ~350 cm^-1) in the solution state, but in the solid state these electronic transitions couple with the core phonon (average energy ~180 cm^-1). The suppression of the staple-shell phonon in the solid state is attributed to the intracluster and cluster-matrix interactions.

Journal of Physical Chemistry Letters published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Name: 2-Phenylethanethiol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts