Author: tianli

Nakayama, Yumiko published the artcileEffect of whitening gel containing vitamins on skin conditions, Related Products of alcohols-buliding-blocks, the publication is Igaku to Yakugaku (2016), 73(7), 899-904, database is CAplus.

This paper presents exptl. results for the effect of whitening gel containing vitamins on skin conditions. A weighed amount of raw materials to obtain the whitening gel containing vitamins. Performing clin. test by evaluating melanin content, brightness, skin wrinkles, skin conditions, statistical anal., and adverse effects. A result which observed from the clin. anal. with improved safety, melanin content and skin brightness, capable of removing wrinkles on the corner of eyes, spots, and dullness, and avoiding toxic side effects.

Igaku to Yakugaku published new progress about 70445-33-9. 70445-33-9 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is 3-((2-Ethylhexyl)oxy)propane-1,2-diol, and the molecular formula is C11H24O3, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Kondo, Hiroki published the artcileσ-Bond Hydroboration of Cyclopropanes, Application of 4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-ol, the publication is Journal of the American Chemical Society (2020), 142(25), 11306-11313, database is CAplus and MEDLINE.

Hydroboration of alkenes is a classical reaction in organic synthesis, in which alkenes react with boranes to give alkylboranes, with subsequent oxidation resulting in alcs. The double bond (π-bond) of alkenes can be readily reacted with boranes owing to its high reactivity. However, the single bond (σ-bond) of alkanes has never been reacted. To pursue the development of σ-bond cleavage, the authors selected cyclopropanes as model substrates since they present a relatively weak σ-bond. Herein, the authors describe an Ir-catalyzed hydroboration of cyclopropanes, resulting in β-Me alkylboronates. These unusually branched boronates can be derivatized by oxidation or cross-coupling chem., accessing designer products that are desired by practitioners of natural product synthesis and medicinal chem. Also, mechanistic studies and theor. studies revealed the enabling role of the catalyst.

Journal of the American Chemical Society published new progress about 25240-59-9. 25240-59-9 belongs to alcohols-buliding-blocks, auxiliary class Boronic acid and ester,Boronic Acids,Boronate Esters, name is 4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-ol, and the molecular formula is C6H13BO3, Application of 4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Li, Yanru published the artcileRegioselective C(sp³)-H alkylation of a fructopyranose derivative by 1,6-HAT, Recommanded Product: ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, the publication is Organic & Biomolecular Chemistry (2021), 19(14), 3124-3127, database is CAplus and MEDLINE.

Regioselective C(sp³)-H alkylation of a fructopyranose derivative using electron-deficient alkenes as alkylation reagents was achieved. The reaction proceeded via 1,6-hydrogen atom transfer under photoredox iridium catalysis. Several functional groups were introduced into the fructopyranose derivative

Organic & Biomolecular Chemistry published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C12H20O6, Recommanded Product: ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Irie, Raku published the artcileStructure Revision of Protoaculeine B, a Post-translationally Modified N-Terminal Residue in the Peptide Toxin Aculeine B, Name: 4,4-Diethoxybutan-1-amine, the publication is Journal of Natural Products (2021), 84(4), 1203-1209, database is CAplus and MEDLINE.

The structure of protoaculeine B, the N-terminal residue of the marine peptide toxin aculeine B, is revised to the cis-1,3-disubstituted tetrahydro-β-carboline framework. We prepared two truncated model compounds that lack a long-chain polyamine using the one-step Pictet-Spengler reaction of tryptophan and compared their NMR, mass spectra, and chem. reactivity with those of the natural protoaculeine B. The synthetic models reproduced the profiles of the natural product well, which confirmed the appropriateness of the structure revision.

Journal of Natural Products published new progress about 6346-09-4. 6346-09-4 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Ether, name is 4,4-Diethoxybutan-1-amine, and the molecular formula is C8H19NO2, Name: 4,4-Diethoxybutan-1-amine.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Osman, Maged A. published the artcileEpoxy-Layered Silicate Nanocomposites and Their Gas Permeation Properties, Recommanded Product: 2-(Benzyl(methyl)amino)ethanol, the publication is Macromolecules (2004), 37(19), 7250-7257, database is CAplus.

Epoxy-OM (organo-montmorillonite) nanocomposites have been synthesized, and their permeability to oxygen and water vapor has been measured. The chem. structure of the organic monolayer ionically bonded to the montmorillonite surface has been varied, and its influence on the swelling, intercalation, and exfoliation behavior of the OM has been studied. Exfoliated aluminosilicate layers build a barrier for the permeating gas mols., while the polymer intercalated tactoids do not contribute much to the permeation barrier performance. The gas permeation through the composites was correlated to the volume fraction of the impermeable inorganic part of the OM. The incorporation of small volume fractions of the platelike nanoparticles in the polymer matrix decreased its permeability coefficient when the interface between the two heterogeneous phases was properly designed. Long alkyl chains enhanced the polymer intercalation but increased the permeability coefficient probably due to phase separation at the interface between the polymer and the inclusions. Matching the surface energy of the OM with that of the matrix as well as tethering polymer mols. to the silicate layers surface enhanced the exfoliation and decreased the permeation coefficient The exfoliation process is governed by interplay of entropic and energetic factors. A macroscopic volume average of the aspect ratio of montmorillonite platelets was deducted from the relative permeability of the nanocomposites by comparing the measured values to numerical predictions of gas permeation through composites of misaligned disk-shaped inclusions. The permeability coefficient of the epoxy matrix was reduced to one-fourth at 5 vol % Bz1OH loading, and the reduction was attributed to the tortuous pathway the gas mols. have to cover during their random walk to penetrate the composite. The transmission rate of water vapor through the composites is more influenced by the permeant-composite interactions and hence the hydrophobicity of the monolayer covering the inclusions surface. At 5 vol % BzC16 loading, the relative vapor transmission rate was reduced to half.

Macromolecules published new progress about 101-98-4. 101-98-4 belongs to alcohols-buliding-blocks, auxiliary class Amine,Benzene,Alcohol, name is 2-(Benzyl(methyl)amino)ethanol, and the molecular formula is C10H15NO, Recommanded Product: 2-(Benzyl(methyl)amino)ethanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Urayama, Teppei published the artcileO₂-enhanced catalytic activity of gold nanoparticles in selective oxidation of hydrosilanes to silanols, Recommanded Product: Triisopropylsilanol, the publication is Chemistry Letters (2015), 44(8), 1062-1064, database is CAplus.

O₂ acts as a nonconsumed activator for gold nanoparticles (AuNPs) in the oxidation of hydrosilanes to silanols with water under O₂ atm, providing an acceleration of more than 200 times relative to the reaction rate under Ar atm. The AuNP catalyst under aerobic conditions exhibits high activity in the oxidation with high turnover numbers (1230000). Various hydrosilanes including less-reactive bulky ones can be converted to the corresponding silanols in excellent yields. Moreover, the present AuNP catalyst is reusable while maintaining the high performance.

Chemistry Letters published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C22H18Cl2N2, Recommanded Product: Triisopropylsilanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Kurimoto, Yuji published the artcileEfficient Synthesis and Properties of [1]Benzothieno[3,2-b]thieno[2,3-d]furans and [1]Benzothieno[3,2-b]thieno[2,3-d]thiophenes, Recommanded Product: Thiophen-3-ol, the publication is Asian Journal of Organic Chemistry (2018), 7(8), 1635-1641, database is CAplus.

Efficient synthesis of benzodithienofurans (BDTF) e.g. I and benzodithienothiophenes (BDTT) e.g. II were achieved by the combination of an addition-elimination reaction, reduction and Pd-catalyzed dehydrogenative cyclization. The synthesis of Π-extended BDTF and BDTT derivatives through the use of coupling reactions was also achieved. The detailed phys. properties like DFT, cyclic voltametry, UV visible absorption and fluorescence of these compounds were investigated. The newly synthesized BDTFs exhibited strong fluorescence compared with BDTTs. 2,2′-bis([1]benzothieno[3,2-b]thieno[2,3-d]furan) (BBTTF) exhibited p-type organic field-effect transistor (OFET) properties.

Asian Journal of Organic Chemistry published new progress about 17236-59-8. 17236-59-8 belongs to alcohols-buliding-blocks, auxiliary class Thiophene,Alcohol, name is Thiophen-3-ol, and the molecular formula is C4H4OS, Recommanded Product: Thiophen-3-ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Butkevich, Alexey N. published the artcileFluorescent Rhodamines and Fluorogenic Carbopyronines for Super-Resolution STED Microscopy in Living Cells, Safety of 3-(Methylamino)phenol, the publication is Angewandte Chemie, International Edition (2016), 55(10), 3290-3294, database is CAplus and MEDLINE.

A range of bright and photostable rhodamines and carbopyronines with absorption maxima in the range of λ=500-630 nm were prepared, and enabled the specific labeling of cytoskeletal filaments using HaloTag technol. followed by staining with 1 μM solutions of the dye-ligand conjugates. The synthesis, photophys. parameters, fluorogenic behavior, and structure-property relationships of the new dyes are discussed. Light microscopy with stimulated emission depletion (STED) provided one- and two-color images of living cells with an optical resolution of 40-60 nm.

Angewandte Chemie, International Edition published new progress about 14703-69-6. 14703-69-6 belongs to alcohols-buliding-blocks, auxiliary class Amine,Benzene,Phenol, name is 3-(Methylamino)phenol, and the molecular formula is C7H9NO, Safety of 3-(Methylamino)phenol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zhou, Xiaoyuan published the artcileLignol Cleavage by Pd/C Under Mild Conditions and Without Hydrogen: A Role for Benzylic CH Activation?, COA of Formula: C15H16O3, the publication is ChemSusChem (2014), 7(6), 1623-1626, database is CAplus and MEDLINE.

The cleavage of CO bonds in lignin model compounds without hydrogen was developed using the com. available Pd/C. Hydrogen donor solvents are helpful for this reaction through transfer hydrogenation, but not necessary. A redox neutral process that utilizes the internal hydrogen source for the cleavage is also possible. An initial mechanistic study indicates that the β-benzylic-H atom in the substrate plays a critical role and that the present system undergoes a process different from previous reports.

ChemSusChem published new progress about 70110-65-5. 70110-65-5 belongs to alcohols-buliding-blocks, auxiliary class Benzene,Alcohol,Ether,Benzene Compounds, name is 2-Phenoxy-1-phenylpropane-1,3-diol, and the molecular formula is C24H20Ge, COA of Formula: C15H16O3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Grigg, R. published the artcileTransition metal-catalyzed N-alkylation of amines by alcohols, SDS of cas: 4543-95-7, the publication is Journal of the Chemical Society, Chemical Communications (1981), 611-12, database is CAplus.

Primary and secondary alcs. alkylate primary and secondary alkyl and heterocyclic amines in the presence of Rh, Ir and Ru compounds at ≤100° to give monoalkylated products. Thus, BuNH₂ was refluxed 8 h in MeOH with RhH(PPh₃)₄ (I) to give 98% BuNHMe. Heterocyclic rings were prepared by inter- or intramol. alkylation. E.g., BuN(CH₂)₄OH was refluxed in dioxane with I to give 56% N-butyltetrahydropyrrole.

Journal of the Chemical Society, Chemical Communications published new progress about 4543-95-7. 4543-95-7 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 4-(Butylamino)butan-1-ol, and the molecular formula is C8H19NO, SDS of cas: 4543-95-7.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts