Author: tianli

Ihsan, Mohammad published the artcileGenetic diversity in nutritional composition of oat (Avena sativa L.) germplasm reported from Pakistan, COA of Formula: C8H8O3, the publication is Saudi Journal of Biological Sciences (2022), 29(3), 1487-1500, database is CAplus and MEDLINE.

In the present study, 30 potential germplasm of oat (Avena sativa L.) were subjected to proximate, elemental, and HPLC anal. to provide a scientific basis to genetic diversity present among them. The extracts of the selected germplasms were also evaluated for their antioxidant potentials through DPPH and ABTS assays. Proximate anal. showed protein contents to be in the range 8.35-17.72% with the highest protein contents in the accession line 22,365 (17.72 ± 0.38%). The genotype-725 showed the highest carbohydrate, and dry matter (53.35 ± 0.01 and 93.50 ± 0.07% resp.) contents whereas, the germplasm-830 contained the highest fat (7.88 ± 0.12%) contents while the highest moisture contents were there in germplasm-22348 (11.95 ± 0.06%). The crude fiber contents (19.67 ± 0.19%) were found high in germplasm-832. The mentioned contents were also correlated to each other where a neg. (-0.431*) correlation was noted for crude protein and carbohydrate while ash content to crude protein has a pos. (0.38*) correlation. A pos. and a neg. correlation were there in Crude fats/crude protein (0.30*) and crude fats/moisture contents (-0.39*) resp. Principal component anal. showed an Eigenvalue of 0.76 with a total variation of 85.01% when applied to proximate components. Based on cluster anal. to proximate composition all the oat germplasms were divided into 5 sub-clusters, where accession numbers 769 and 817 were found to be the most diverse genotypes. The elemental anal. confirmed the presence of magnesium (2.89-7.62 mg/L), sodium (3.71-8.03 mg/L), manganese (0.93-3.71 mg/L), copper (0.35-3.36 mg/L), iron (2.15-6.82 mg/L), zinc (1.30-3.37 mg/L), chromium (0.37-3.34 mg/L), and potassium (50.70-59.60 mg/L) in the selected germplasms. Principal component anal. for elemental composition showed the total variation of 73.75% with the Eigenvalue of 0.97. Cluster anal. on an elemental basis divided all the oat germplasms into 7 sub-clusters where accession numbers 769 and 22,350 were found to be the most diverse germplasm. Phytochem. anal. performed through HPLC resulted in the identification of nine possible compounds (malic acid, epigallocatechin gallate, quercetin, morin, ellagic acid, catechin hydrate, rutin, pyrogallol, and mandelic acid) in various germplasm of oat. A concentration-dependent antioxidant response was recorded when extracts were tested as an inhibitor of DPPH and ABTS free radicals. The results revealed that oat grains are a good source of nutrients, minerals, and phytochems. that can be used as nutraceuticals and as food. The genetic differences revealed that this plant can be grown under varied environmental conditions.

Saudi Journal of Biological Sciences published new progress about 90-64-2. 90-64-2 belongs to alcohols-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Alcohol,Natural product, name is 2-Hydroxy-2-phenylacetic acid, and the molecular formula is C8H8O3, COA of Formula: C8H8O3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Tolnai, Gergely L. published the artcileEfficient O-Functionalization of Carbohydrates with Electrophilic Reagents, Computed Properties of 20880-92-6, the publication is Angewandte Chemie, International Edition (2016), 55(37), 11226-11230, database is CAplus and MEDLINE.

Novel methodol. for O-functionalization of carbohydrate derivatives has been established using bench-stable and easily prepared iodonium(III) reagents. Both electron-withdrawing and electron-donating aryl groups were introduced under ambient conditions and without precautions to exclude air or moisture. Furthermore, the approach was extended both to full arylation of cyclodextrin, and to trifluoroethylation of carbohydrate derivatives This is the first general approach to introduce traditionally non-electrophilic groups into any of the OH groups around the sugar backbone. The methodol. will be useful both in synthetic organic chem. and biochem., as important functional groups can be incorporated under simple and robust reaction conditions in a fast and efficient manner.

Angewandte Chemie, International Edition published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C13H10O2, Computed Properties of 20880-92-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Nizamov, I. S. published the artcileDithiophosphonation of 4-(1H-pyrrol-1-yl)phenol and 4-(1H-imidazol-1-yl)phenol, HPLC of Formula: 23351-09-9, the publication is Russian Journal of Organic Chemistry (2015), 51(9), 1272-1276, database is CAplus.

Reactions of 4-(1H-pyrrol-1-yl)phenol and 4-(1H-imidazol-1-yl)phenol with 2,4-diaryl-1,3,2λ⁵,4λ⁵– dithiadiphosphetane 2,4-disulfides gave the corresponding O-4-hetarylphenyl hydrogen arylphosphonodithioates which were converted into ammonium salts. The latter showed antimicrobial activity against Gram pos. bacteria and antifungal activity against fungi of the genus Candida.

Russian Journal of Organic Chemistry published new progress about 23351-09-9. 23351-09-9 belongs to alcohols-buliding-blocks, auxiliary class Pyrrole,Benzene,Alcohol, name is 4-(1H-Pyrrol-1-yl)phenol, and the molecular formula is C10H9NO, HPLC of Formula: 23351-09-9.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Tikker, Priit published the artcileOxidation of aqueous bisphenols A and S by pulsed corona discharge: Impacts of process control parameters and oxidation products identification, SDS of cas: 80-09-1, the publication is Chemical Engineering Journal (Amsterdam, Netherlands) (2022), 135602, database is CAplus.

Widespread usage of bisphenol A (BPA) and its potential replacement bisphenol S (BPS) has led to their presence in natural waterbodies. The exptl. research into degradation of both aqueous pollutants by application of gas-phase pulsed corona discharge (PCD) was undertaken with variation of process control parameters, pulse repetition frequency, gas-liquid contact surface and addition of surfactant OH-radical scavenger sodium dodecyl sulfate (SDS). Although the contact surface variation had only a moderate impact on bisphenols degradation, its effect was stronger in total organic carbon removal. The addition of SDS showed a moderately neg. impact on energy efficiency at all studied conditions. The obtained results showed energy efficiency surpassing the closest competitors, ozonation and other elec. discharge processes. The detected major oxidation intermediates were mainly formed through hydroxylation and cracking of benzene rings, followed by further degradation into short chained aliphatic acids. The oxidation end-products were quantified as acetate, formate and oxalate.

Chemical Engineering Journal (Amsterdam, Netherlands) published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C14H26O2, SDS of cas: 80-09-1.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Kapustina, N. I. published the artcileOxidation of 1-methylcyclobutanol with lead(IV) and manganese(III) compounds, Quality Control of 20117-47-9, the publication is Izvestiya Akademi Nauk, Seriya Khimicheskaya (1992), 2760-3, database is CAplus.

1-Phenyl-4-pentanone is formed as the main product of reaction between 1-methylcyclobutanol (I) and Pb(OAc)₄ in benzene. Oxidation of I with Mn(OAc)₃ in AcOH leads to a mixture of Me Pr ketone and 2,9-decanedione. Reaction of I with Pb(OAc)₄ or Mn(OAc)₃ in the presence of a metal halide yields selectively the corresponding 1-substituted (chloro, bromo, thiocyano or cyano) 4-pentanone.

Izvestiya Akademi Nauk, Seriya Khimicheskaya published new progress about 20117-47-9. 20117-47-9 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic cyclic hydrocarbon,Alcohol, name is 1-Methylcyclobutan-1-ol, and the molecular formula is C5H10O, Quality Control of 20117-47-9.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Sasikumar, M. published the artcileSimple and efficient synthesis of (S)-dapoxetine, Related Products of alcohols-buliding-blocks, the publication is Synthetic Communications (2012), 42(20), 3061-3067, database is CAplus.

A refinement in the synthetic strategy for (S)-dapoxetine was described. The key features of synthetic strategy include (a) a Sharpless asym. epoxidation and regioselective reductive ring opening of a 2,3-epoxy alc. to elaborate the hydroxy-bearing stereogenic center at the benzylic position; (b) regioselective functionalization of the 1-naphthol and the amine functionality through Mitsunobu procedures; and (c) Eschweiler-Clarke reductive methylation to access the target mol.

Synthetic Communications published new progress about 156453-53-1. 156453-53-1 belongs to alcohols-buliding-blocks, auxiliary class Chiral,Benzene,Naphthalene,Alcohol,Ether, name is (R)-3-(Naphthalen-1-yloxy)-1-phenylpropan-1-ol, and the molecular formula is C19H18O2, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Chen, Chen published the artcileDesign, synthesis and preliminary bioactivity studies of indomethacin derivatives as Bcl-2/Mcl-1 dual inhibitors, Application of 2-((4-(4-Bromophenylsulfonamido)-1-hydroxynaphthalen-2-yl)thio)acetic acid, the publication is Bioorganic & Medicinal Chemistry (2019), 27(13), 2771-2783, database is CAplus and MEDLINE.

Bcl-2 family proteins, which divides into pro-apoptosis proteins and anti-apoptosis proteins, are involved in cell apoptosis progression. As numerous studies illustrated, targeting Bcl-2 family proteins is more and more attractive and practicable to cancer treatment. In this work, we designed and synthesized a series of indomethacin derivatives as new inhibitors for Bcl-2 family proteins. Our results of binding assay to Bcl-2 proteins, MTT assay and apoptotic assay indicated that some compounds had potent binding affinity to Bcl-2/Mcl-1 but not Bcl-xL. Furthermore, compound 8j showed improved anti-proliferative activity than known Bcl-2 inhibitor WL-276.

Bioorganic & Medicinal Chemistry published new progress about 518303-20-3. 518303-20-3 belongs to alcohols-buliding-blocks, auxiliary class Apoptosis,Bcl-2, name is 2-((4-(4-Bromophenylsulfonamido)-1-hydroxynaphthalen-2-yl)thio)acetic acid, and the molecular formula is C18H14BrNO5S2, Application of 2-((4-(4-Bromophenylsulfonamido)-1-hydroxynaphthalen-2-yl)thio)acetic acid.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Chen, Yifei published the artcileStrontium oxides with enzyme-like activity: A colorimetric sensor array for highly sensitive discrimination of bisphenols, Safety of 4,4′-Sulfonyldiphenol, the publication is Sensors and Actuators, B: Chemical (2022), 131869, database is CAplus.

Bisphenols are widely used in food packaging materials, and because of their endocrine disrupting effects on the human body, fast yet facile detection is essential for food safety and human health. Traditional anal. methods face disadvantages of cumbersome operation and the need of bulk instruments. To circumvent these issues, we constructed colorimetric sensor arrays based on peroxidase-like activities of three strontium oxides for four bisphenols determination Bisphenols are absorbed on surface of strontium oxides, blocking catalytic sites and leading to decline of enzyme-like activities in turn. Different bisphenols have diverse inhibition effect on catalytic activities of the three nanozymes, and each bisphenol possesses a unique fingerprint. Though principal component anal., bisphenol A, bisphenol S, bisphenol B and bisphenol AF with concentrations ranging from 0.0002 to 1μg mL^-1 were discerned well by the developed sensor arrays. Addnl., different concentrations of each bisphenol and different ratios of mixed bisphenols were successfully discriminated, and canned fruit as real sample was applied to evaluate practical applicability of the nanozyme based sensor arrays. This work is expected to provide a simple and fast method for discrimination of structural analogs and contribute to food quality and safety monitoring aspects.

Sensors and Actuators, B: Chemical published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C12H10O4S, Safety of 4,4′-Sulfonyldiphenol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Luo, Zhicheng published the artcileTransition metal-like carbocatalyst, COA of Formula: C15H16O3, the publication is Nature Communications (2020), 11(1), 4091, database is CAplus and MEDLINE.

Catalytic cleavage of strong bonds including hydrogen-hydrogen, carbon-oxygen, and carbon-hydrogen bonds is a highly desired yet challenging fundamental transformation for the production of chems. and fuels. Transition metal-containing catalysts are employed, although accompanied with poor selectivity in hydrotreatment. Here we report metal-free nitrogen-assembly carbons (NACs) with closely-placed graphitic nitrogen as active sites, achieving dihydrogen dissociation and subsequent transformation of oxygenates. NACs exhibit high selectivity towards alkylarenes for hydrogenolysis of aryl ethers as model bio-oxygenates without over-hydrogeneration of arenes. Activities originate from cooperating graphitic nitrogen dopants induced by the diamine precursors, as demonstrated in mechanistic and computational studies. We further show that the NAC catalyst is versatile for dehydrogenation of ethylbenzene and tetrahydroquinoline as well as for hydrogenation of common unsaturated functionalities, including ketone, alkene, alkyne, and nitro groups. The discovery of nitrogen assembly as active sites can open up broad opportunities for rational design of new metal-free catalysts for challenging chem. reactions.

Nature Communications published new progress about 70110-65-5. 70110-65-5 belongs to alcohols-buliding-blocks, auxiliary class Benzene,Alcohol,Ether,Benzene Compounds, name is 2-Phenoxy-1-phenylpropane-1,3-diol, and the molecular formula is C15H16O3, COA of Formula: C15H16O3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Tan, Hongbo published the artcileEffect of organic alkali on compressive strength and hydration of wet-grinded granulated blast-furnace slag containing Portland cement, HPLC of Formula: 122-20-3, the publication is Construction and Building Materials (2019), 10-18, database is CAplus.

In this study, a com. available ground granulated blast-furnace slag (GGBS) was further processed by wet grinding, and WGGBS (wet-grinded GGBS) slurry with superfine particles was obtained. To avoid self-hydration of slag and augment the grinding efficiency, one com. available polycarboxylate superplasticizer was added. The binder, composed of 10.0% cement and 90.0% WGGBS with the addition of 0.05% triethanolamine (TEA) and 0.05% triisopropanolamine (TIPA), was designed; the cement was added to provide alkali environment and calcium ions, and organic alkali was used to promote the dissolution of GGBS. The compressive strength of mortar and hydration mechanism was investigated. The results showed that wet grinding exhibited high grinding efficiency; D(50) value of particle size distribution of WGGBS was reduced from 18μm to 2.10μm by wet grinding for one hour. Compressive strength of hardened WGGBS mortar was 20 MPa and 28 MPa at 7 d and 28 d, and 10% cement replacement ratio of the WGGBS increased the strength to 24.6 MP at 7 d and 32.2 MPa at 28 d. Furthermore, in C-WGGBS, 0.05% TEA increased the 7 d strength by 23%, with the value of 30.27 MPa, but 0.05%TIPA slightly reduced it to 23.5 MPa, with a decrease by 5%. Mechanism behind the increase was due to the accelerated formation of hydrotalcite-like phase, despite the retarding effect on formation of C-(A)S-H gel; the slight decline by TIPA was mainly because of the retarding effect of formation of C-(A)S-H gel as well as its air-entraining effect. Moreover, both TEA and TIPA increased the 28 d strength of cement-WGGBS system, because TEA and TIPA were able to facilitate ferric and aluminum dissolution and expedite the formation of C-(A)S-H gel as well as hydrotalcite-like phase. Addnl., it was worth noting that 0.05% TEA could make 28 d strength of the binder, composed of only 10% cement, reach 43.7 MPa, in accordance with the requirement of 42.5 grade cement.

Construction and Building Materials published new progress about 122-20-3. 122-20-3 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment, name is Triisopropanolamine, and the molecular formula is C25H23NO4, HPLC of Formula: 122-20-3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts