Author: tianli

Scharinger, Fabian;Palvolgyi, Adam Mark;Weisz, Melanie;Weil, Matthias;Stanetty, Christian;Schnuerch, Michael;Bica-Schroder, Katharina published 《Sterically Demanding Flexible Phosphoric Acids for Constructing Efficient and Multi-Purpose Asymmetric Organocatalysts》. The research results were published in《Angewandte Chemie, International Edition》 in 2022.SDS of cas: 119-47-1 The article conveys some information:

A novel approach for various asym. transformations of cyclic enones, e.g., 2-cyclohepten-1-one has been described. The combination of readily accessible chiral diamines and sterically demanding flexible phosphoric acids resulted in a simple and highly tunable catalyst framework. The careful optimization of the catalyst components led to the identification of a particularly powerful and multi-purpose organocatalyst, which was successfully applied for asym. epoxidations, aziridinations, aza-Michael-initiated cyclizations, as well as for a novel Robinson-like Michael-initiated ring closure/aldol cyclization. High catalytic activities and excellent stereocontrol were observed for all four reaction types, indicating the excellent versatility of the catalytic system. Furthermore, a simple change in the diamine’s configuration provided easy access to both product antipodes in all cases. The experimental procedure involved many compounds, such as 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) .

SDS of cas: 119-47-12,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

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HPLC of Formula: 599-64-4《A tiered high-throughput screening approach for evaluation of estrogen and androgen receptor modulation by environmentally relevant bisphenol A substitutes》 was published in 2020. The authors were Keminer, Oliver;Teigeler, Matthias;Kohler, Manfred;Wenzel, Andrea;Arning, Juergen;Kassner, Franziska;Windshuegel, Bjoern;Eilebrecht, Elke, and the article was included in《Science of the Total Environment》. The author mentioned the following in the article:

Bisphenol A (BPA) is a high production volume chem. with a broad application spectrum. As an endocrine disrupting chem., mainly by modulation of nuclear receptors (NRs), BPA has an adverse impact on organisms and is identified as a substance of very high concern under the European REACH regulation. Various BPA substitution candidates have been developed in recent years, however, information concerning the endocrine disrupting potential of these substances is still incomplete or missing. In this study, we intended to investigate the endocrine potential of BPA substitution candidates used in environmentally relevant applications such as thermal paper or epoxy resins. Based on an extensive literature and patent search, 33 environmentally relevant BPA substitution candidates were identified. In order to evaluate the endocrine potential of the BPA replacements, a screening cascade consisting of biochem. and cell-based assays was employed to investigate substance binding to the NRs estrogen receptor α and β, as well as androgen receptor, co-activator recruitment and NR-mediated reporter gene activation. In addition, a computational docking approach for retrospective prediction of receptor binding was carried out. Our results show that some BPA substitution candidates, for which so far no or only very few data were available, possess a substantial endocrine disrupting potential (TDP, BPZ), while several substances (BPS, D-8, DD70, DMP-OH, TBSA, D4, CBDO, ISO, VITC, DPA, and DOPO) did not reveal any NR binding. To complete the study, the researchers used 4-(2-Phenylpropan-2-yl)phenol (cas: 599-64-4) .

4-(2-Phenylpropan-2-yl)phenol(cas:599-64-4) is a natural product found in Panax ginseng.HPLC of Formula: 599-64-4 4-(2-Phenylpropan-2-yl)phenol is a useful reagent for preparing and characterizing aromatic polyphosphonates as high refractive index polymers.

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Dias, L. G.;Hacke, A.;Bergara, S. F.;Villela, O. V.;Mariutti, L. R. B.;Bragagnolo, N. published 《Identification of volatiles and odor-active compounds of aromatic rice by OSME analysis and SPME/GC-MS》. The research results were published in《Food Research International》 in 2021.Application In Synthesis of 4-tert-Amylphenol The article conveys some information:

During cooking, aromatic rice has a pleasant and characteristic aroma, a relevant factor to add sale value and attract consumer interest. This work studied the volatile compounds of aromatic rice (IAC 500) aiming at identifying those responsible for the aroma and flavor of the cooked rice. The description of the aromatic notes of the IAC 500 rice was carried out by a trained and selected sensory panel, followed by olfactometry (OSME) and identification by GC-MS of the rice volatile compounds extracted by SPME. A total of 80 volatiles was sensorially perceived and/or detected in the chromatog. effluent, of which 65 were identified, 44 presented some odor, and 36 were odorless. Among the odorous compounds, 15 were not detected by GC-FID or GC-MS. This study confirmed the compound 2-acetyl-1-pyrroline as the impacting volatile compound to the aroma of aromatic rice since it presented a very low percentage of area in the chromatogram and a high odor intensity. Other 43 compounds presented odor in lower intensities, but also contributed to the overall aroma of IAC 500 rice. From the 11 aromatic notes mentioned by the trained panel (cooked vegetable/seed, corn, hominy, green, porridge, popcorn, fresh baked cake/bread, milk, caramel, tapioca flour and flower), eight were related to the volatile compounds responsible for their aroma. And 4-tert-Amylphenol (cas: 80-46-6) was used in the research process.

4-tert-acylphenol (cas:80-46-6) contains hydroxyl group.Some low molecular weight alcohols of industrial importance are produced by the addition of water to alkenes. Ethanol, isopropanol, 2-butanol, and tert-butanol are produced by this general method. Application In Synthesis of 4-tert-Amylphenol

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《Certain High Production Volume Chemicals; Test Rule and Significant New Use Rule; Fourth Group of Chemicals》 was published in 2011. The article was appeared in 《Federal Register》. The authors have made some progress in their research.

EPA is proposing to issue a test rule under Toxic Substances Control Act (TSCA) section 4(a)(1)(B) to require manufacturers and processors of 23 high production volume (HPV) chem. substances to develop screening-level health, environmental, and fate data based on the potential for substantial exposures of workers and consumers to these chems. EPA is also proposing to issue simultaneously a significant new use rule (SNUR) for another 22 HPV chem. substances under tSCA section 5(a)(2). The SNUR would require persons to file a significant new use notice (SNUN) with EPA prior to manufacturing, importing, or processing any of these chem. substances for use in a consumer product or for any use, or combination of uses, that is reasonably likely to exposure 1,000 or more workers at a single corporate entity. The required notification would provide EPA with the opportunity to evaluate the intended use and, if necessary, to prohibit or limit that activity before it occurs. EPA is also soliciting comment on a number of issues with regard to both the test rule and the SNUR. The experimental procedure involved many compounds, such as 2,5-Dimethyl-2,5-hexanediol (cas: 110-03-2) .

2,5-Dimethyl-2,5-hexanediol(cas:110-03-2) on heteropoly acid catalyzed dehydration yields cyclic ethers via stereospecific intramolecular SN2 mechanism. It reacts with nitriles in concentrated sulfuric acid to yield Δ1-pyrrolines.Safety of 2,5-Dimethyl-2,5-hexanediol

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Jiang, Haifeng;Liu, Haipeng;Liu, Baolin;Zhang, Yu;Li, Shu;Chen, Jie published 《Effect of Cellulose-Lignin Interactions on Catalytic Pyrolysis over Formate Salt Catalysts》 in 2021. The article was appeared in 《ACS Sustainable Chemistry & Engineering》. They have made some progress in their research.HPLC of Formula: 119-47-1 The article mentions the following:

This work studied the effect of cellulose-lignin interactions under potassium formate (HCOOK) and nickel formate (Ni(HCOO)₂) on behavior and product distributions. The results indicated that the presence of HCOOK affected the whole thermal decomposition process, while the effect of Ni(HCOO)₂ was mainly manifested before 339°C. The interaction under the action of HCOOK favored the generation of carbonyl compounds, and the catalytic pyrolysis with Ni(HCOO)₂ was better for formating phenols. The high peak intensities of CO and CH₄ were achieved by adding nickel formate and potassium formate, resp. It was obviously different from noncatalytic pyrolysis. The evolution of a char structure further revealed that different formate salts had different effects on the interactions. The statistical method according to the distribution of the liquid component confirmed that HCOOK had the strongest effect for reducing the cellulose-lignin interactions. To complete the study, the researchers used 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) .

HPLC of Formula: 119-47-12,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

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Product Details of 2425-77-6《Essential oil obtained from Thlaspi arvense L. leaves and seeds using microwave-assisted hydrodistillation and extraction in situ by vegetable oil and its antifungal activity against Penicillium expansum》 was published in 2022. The authors were Zhao, Ru;Ben, Ailing;Wei, Mengxia;Ruan, Ming;Gu, Huiyan;Yang, Lei, and the article was included in《LWT–Food Science and Technology》. The author mentioned the following in the article:

An improved approach was developed to obtain essential oil from Thlaspi arvense L. leaves (TAL) and seeds (TAS) using microwave-assisted hydrodistillation and extraction in situ by vegetable oil. Some potential parameters that affected the yield of essential oils were systematically investigated. Under the obtained optimization conditions, the maximized yields of TAL and TAS essential oils were 0.77 ± 0.02 mg/g and 2.69 ± 0.08 mg/g, resp. The results analyzed by GC-MS revealed that the main component of TAS essential oil was allyl isothiocyanate (AITC), which accounted for 44.69% of the total essential oil content. The proportion of AITC in TAL essential oil, however, was only 9.66%. Results showed that they all had significant inhibition on P. expansum, with AITC exhibiting the greatest inhibition on P. expansum. The study of antifungal activity indicates that AITC has potential application value and broad application prospects in food preservation-related fields in the future.2-Hexyl-1-decanol (cas: 2425-77-6) were involved in the experimental procedure.

2-Hexyl-1-decanol(cas: 2425-77-6) may be employed as an organic solvent to study the extraction of non-polar acidic drugs from human plasma by parallel artificial liquid membrane extraction (PALME). Product Details of 2425-77-6

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LaBrecque, G. C.;Gouck, H. K. published 《Compounds affecting fertility in adult houseflies》. The research results were published in《Journal of Economic Entomology》 in 1963.Computed Properties of C8H12ClNO2 The article conveys some information:

Of 1100 compounds that were tested, 20 caused sterility in adult Musca domestica when given in the food. P,P-Bis(1-aziridinyl)-N-(p-methoxyphenyl)phosphinic amide, 5-fluoroorotic acid, and 1,4-piperazinediylbis[bis(1-aziridinyl)phosphinic oxide] induced sterility without apparent toxic effect over the broadest range of concentrations, from 5% to 0.1% or 0.25%. The experimental procedure involved many compounds, such as 5-(hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloride (cas: 148-51-6) .

5-(hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloride(cas:148-51-6 Computed Properties of C8H12ClNO2) is a strong antagonist of vitamin B6. Deoxypyridoxine hydrochloride has been used as an analytical reference standard for the quantification of the analyte in food samples using high performance liquid chromatography.

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Related Products of 119-47-1In 2021, Sicar, Milica Rankov;Micic, Radoslav;Tomic, Milan;Durisic-Mladenovic, Natasa published 《Efficiency of different additives in the improvement of the oxidation stability of fatty acid methyl esters with different properties》. 《Journal of the Serbian Chemical Society》published the findings. The article contains the following contents:

This study evaluates six formulations in improving the oxidation stability of different fatty acid Me esters (MEs). Two MEs differed in the unsaturation levels as they were synthesized from different feedstock: a blend of soybean and sunflower oils, and waste cooking oil; they did not fulfill the requirements of the EN 14214 standard concerning their oxidation stability (≈0.6 h) and some impurities. The third MEs (SoSuME-EN) were fully compliant with the standard Five formulations were phenolic-based, containing single or mixed antioxidant compounds of different mol. structures; one was amine-based. Different dosages of the formulations were added to the ME samples (corresponding to the addition range 50-48300 ppm). The MEs stability expressed as induction periods, IP, determined by the Rancimat method, were used for the calculation of stabilization factors, SF, indicating the efficiency of the applied formulation. The formulation containing 2-(1,1-dimethyl-ethyl)-1,4-benzenediol was the most efficient concerning the lowest consumption rate and the highest SF achieved for the low quality ME. 2,2′-Methylene-bis-(4-methyl-6-tert-butylphenol) was linked with higher antioxidant potency than the amine-based formulation and the phenolic compounds with two bulky tert-Bu groups. Among the 4 selected phenolic additives, butylated hydroxytoluene and 2,2′-methylene-bis-(4-methyl-6-tert-butylphenol) had similar efficiency in SoSuME-EN (at ≈500 ppm they produced SF ≈ 2), while it took twice of this amount for mixed butylphenols to achieve the same effect. The experimental procedure involved many compounds, such as 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) .

Related Products of 119-47-12,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

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Yamamoto, Daisuke;Soga, Masayuki;Ansai, Hiromasa;Makino, Kazuishi published 《Manganese-catalysed hydroperoxidation of carbon-carbon double bonds using molecular oxygen present in air and hydroxylamine under ambient conditions》. The research results were published in《Organic Chemistry Frontiers》 in 2016.Recommanded Product: rel-(1R,2S)-1,2-Diphenylethane-1,2-diol The article conveys some information:

A highly efficient manganese-catalyzed hydroperoxidn. of carbon-carbon double bonds of enynes as well as styrene derivatives using N-hydroxyphthalimide, N-hydroxybenzotriazole or N-hydroxysuccinimide was developed. This reaction proceeded at room temperature through the direct incorporation of mol. oxygen present in air. The required catalytic loading of manganese(III) acetylacetonate was extremely low (generally 0.02-0.5 mol%, and a min. of 0.001 mol%). The experimental procedure involved many compounds, such as rel-(1R,2S)-1,2-Diphenylethane-1,2-diol (cas: 579-43-1) .

rel-(1R,2S)-1,2-Diphenylethane-1,2-diol(cas: 579-43-1 Recommanded Product: rel-(1R,2S)-1,2-Diphenylethane-1,2-diol) has been used in the preparation of trans-methyl meso-hydrobenzoin phosphite.

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Bogacki, Jan;Marcinowski, Piotr;Bury, Dominika;Krupa, Monika;Sciezynska, Dominika;Prabhu, Prasanth published 《Magnetite, hematite and zero-valent iron as co-catalysts in advanced oxidation processes application for cosmetic wastewater treatment》. The research results were published in《Catalysts》 in 2021.Quality Control of 3,7-Dimethyloctan-3-ol The article conveys some information:

There is a need for more effective methods of industrial wastewater treatment. Cosmetic wastewater was collected and subjected to H₂O₂/Fe₃O₄/Fe₂O₃/Fe⁰ and UV/H₂O₂/Fe₃O₄/Fe₂O₃/Fe⁰ process treatment. Total organic carbon (TOC) was decreased from an initial 306.3 to 134.1 mg/L, 56.2% TOC removal, after 120 min of treatment for 1:1 H₂O₂/COD mass ratio and 500/500/1000 mg/L Fe₃O₄/Fe₂O₃/Fe⁰ catalyst doses. The application chromatog. anal. allowed for the detection and identification of pollutants present in the wastewater. Identified pollutants were removed during the treatment processes. Processes carried out at a pH greater than 3.0 were ineffective. The UV process was more effective than the lightless process. The applied processes are effective methods for wastewater treatment. Chromatog. results confirmed the effectiveness of the treatment method. The kinetics of the process were described by the modified second-order model. On the basis of ANOVA results, the hypothesis regarding the accuracy and reproducibility of the research was confirmed. To complete the study, the researchers used 3,7-Dimethyloctan-3-ol (cas: 78-69-3) .

3,7-Dimethyloctan-3-ol(cas:78-69-3) is a fatty alcohol that is 3-octanol substituted by methyl groups at positions 3 and 7.Quality Control of 3,7-Dimethyloctan-3-ol Metabolite observed in cancer metabolism. It has a role as a human metabolite.

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