Author: tianli

Liu, Cheng published the artcile< Solvent-induced synthesis and crystal structures of copper(II) complexes derived from 4-chloro-2-[(2-hydroxymethylphenylimino)methyl]phenol with antibacterial activity>, Synthetic Route of 5344-90-1, the main research area is copper hydroxymethylphenyliminophenolate multinuclear complex preparation bactericide; crystal structure copper hydroxymethylphenyliminophenolate multinuclear complex.

Two new polynuclear copper(II) complexes, [Cu2L2] (1) and [Cu4L4]CH2Cl2 (2), where L is 4-chloro-2-[(2-hydroxymethylphenylimino)methyl]phenolate, were synthesized and characterized by IR and UV-Vis spectroscopy. The mol. structures of the complexes were confirmed by single-crystal X-ray determination The Cu ions in dinuclear complex 1 are in square planar coordination, while those in tetranuclear complex 2 are in square pyramidal coordination. The solvents used in the synthesis and crystallization play an important role for the formation of the final structures of the complexes. The Schiff base and two copper complexes were assayed for antibacterial activities by the MTT method.

Journal of Coordination Chemistry published new progress about Antibacterial agents. 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Synthetic Route of 5344-90-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Tamoradi, Taiebeh; Ghadermazi, Mohammad; Ghorbani-Choghamarani, Arash published the artcile< Ni(II)-Adenine complex coated Fe3O4 nanoparticles as high reusable nanocatalyst for the synthesis of polyhydroquinoline derivatives and oxidation reactions>, Recommanded Product: 2-(Phenylthio)ethanol, the main research area is sulfoxide disulfide polyhydroquinoline preparation green chem; nickel complex immobilized adenine magnetic nanoparticle preparation oxidation catalyst.

In the present study, Fe3O4 nanoparticles were prepared via simple and versatile procedure. Then, a novel and green catalyst was synthesized by the immobilization of Ni on Fe3O4 nanoparticles coated with adenine. The activity of this nanostructure compound was examined for the oxidation of sulfides, oxidative coupling of thiols and synthesis of polyhydroquinolines. The prepared catalyst was characterized by Fourier transform IR spectroscopy (FT-IR), SEM (SEM), energy-dispersive X-ray spectroscopy (EDS), inductively coupled plasma optical emission spectroscopy (ICP-OES), X-ray Diffraction (XRD), thermal gravimetric anal. (TGA), and vibrating sample magnetometer (VSM) measurements. This organometallic catalyst was recovered by the assistance of an external magnetic field from the reaction mixture and reused for seven continuous cycles without noticeable change in its catalytic activity.

Applied Organometallic Chemistry published new progress about Aryl aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Recommanded Product: 2-(Phenylthio)ethanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Tang, Yun-Zhi; Tan, Yu-Hui; Zhu, Jian-Wu; Ji, Fa-Ming; Xiong, Ting-Ting; Xiao, Wen-Zhong; Liao, Chun-Fa; Xiong, Ren-Gen published the artcile< Novel Three-Dimensional Anion-Type Eight-Coordinated Cd(II) Coordination Polymer with Binuclear Cadmium Building Units>, Application of C14H8N2Na2O6, the main research area is cadmium dipentum DMF polymeric preparation structure; crystal structure cadmium dipentum eight coordinate polymeric.

The 3-dimensional polymeric complex {[Cd2(DPT)3(DMF)6]·(2H3O)+} n (DPT = dipentum = 3,3-azo-bis(6-hydroxybenzoic carboxylic acid), DMF = N,N’- dimethylformamide) with binuclear Cd as building block was obtained from hydrothermal reaction of CdCl2·4H2O with medicine dipentum Na.

Crystal Growth & Design published new progress about Coordination number, eight. 6054-98-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C14H8N2Na2O6, Application of C14H8N2Na2O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Khan, M. A.; Al-Attas, Tareq A.; Yasri, Nael G.; Zhao, Heng; Larter, Stephen; Hu, Jinguang; Kibria, Golam Md published the artcile< Techno-economic analysis of solar-powered biomass electrolysis pathway for coproduction of hydrogen and value-added chemicals>, Formula: C6H10O8, the main research area is hydrogen techno economic analysis solar biomass electrolysis.

Electrochem. oxidation of biomass to fuels and value-added chems. represents an emerging strategy for storing renewable energy and achieving a higher grade of sustainability in chem. industries. While research is still in its infancy, it is important to analyze the economic feasibility of such a process. In this study, we present a detailed techno-economic anal. (TEA) of a potential photo-biorefinery approach for sunlight-driven electro-oxidation of glucose to produce valuable fuels and chems. i.e., H2, gluconic acid (GNA) and glucaric acid (GRA). Under a base case scenario, the results are promising with a min. selling price (MSP) of GRA at $6.94 per kg, which will be ~70% lower than the current market price. The detailed breakdown and sensitivity anal. suggest that unlike conventional water electrolysis, the cost of raw materials and separation has a significant impact on the economics. Furthermore, we also establish performance targets for conversion (90%), selectivity (90%), feed concentration (0.5 M) and operating c.d. (0.4 A cm-2) such that if these targets are achieved, photo-electrochem. conversion of biomass to fuels and chems. can become a very profitable option with a MSP of GRA as low as $1.42 per kg.

Sustainable Energy & Fuels published new progress about Analysis (Techno-economic). 87-73-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H10O8, Formula: C6H10O8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Liu, Yinglong; Hou, Wenpeng; Jin, Jie; Christensen, Michael J.; Gu, Lijun; Cheng, Chen; Wang, Jianfeng published the artcile< Epichloe gansuensis increases the tolerance of Achnatherum inebrians to low-p stress by modulating amino acids metabolism and phosphorus utilization efficiency>, Formula: C6H10O8, the main research area is Epichloe Achnatherum growth phosphorus amino acid; Epichloë gansuensis; grass; low P stress; metabolomics.

In the long-term evolutionary process, Achnatherum inebrians and seed-borne endophytic fungi, Epichloe gansuensis, formed a mutually beneficial symbiosis relationship, and Epichloe gansuensis has an important biol. role in improving the tolerance of host grasses to abiotic stress. In this work, we first assessed the effects of Epichloe gansuensis on dry weight, the content of C, N, P and metal ions, and metabolic pathway of amino acids, and phosphorus utilization efficiency (PUE) of Achnatherum inebrians at low P stress. Our results showed that the dry weights, the content of alanine, arginine, aspartic acid, glycine, glutamine, glutamic acid, L-asparagine, lysine, phenylalanine, proline, serine, threonine, and tryptophan were higher in leaves of Epichloe gansuensis-infected (E+) Achnatherum inebrians than Epichloe gansuensis-uninfected (E-) Achnatherum inebrians at low P stress. Further, Epichloe gansuensis increased C content of roots compared to the root of E- plant at 0.01 mM P and 0.5 mM P; Epichloe gansuensis increased K content of leaves compared to the leaf of E- plant at 0.01 mM P and 0.5 mM P. Epichloe gansuensis reduced Ca content of roots compared to the root of E- plant at 0.01 mM P and 0.5 mM P; Epichloe gansuensis reduced the content of Mg and Fe in leaves compared to the leaf of E- plant at 0.01 mM P and 0.5 mM P. In addition, at low P stress, Epichloe gansuensis most probably influenced aspartate and glutamate metabolism; valine, leucine, and isoleucine biosynthesis in leaves; and arginine and proline metabolism; alanine, aspartate, and glutamate metabolism in roots. Epichloe gansuensis also affected the content of organic acid and stress-related metabolites at low P stress. In conclusion, Epichloe gansuensis improves Achnatherum inebrians growth at low P stress by regulating the metabolic pathway of amino acids, amino acids content, organic acid content, and increasing PUE.

Journal of Fungi published new progress about Achnatherum inebrians. 87-73-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H10O8, Formula: C6H10O8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Sebastiana, M.; Gargallo-Garriga, A.; Sardans, J.; Perez-Trujillo, M.; Monteiro, F.; Figueiredo, A.; Maia, M.; Nascimento, R.; Silva, M. Sousa; Ferreira, A. N.; Cordeiro, C.; Marques, A. P.; Sousa, L.; Malho, R.; Penuelas, J. published the artcile< Metabolomics and transcriptomics to decipher molecular mechanisms underlying ectomycorrhizal root colonization of an oak tree>, Computed Properties of 492-62-6, the main research area is metabolomic transcriptomic decipher mol mechanism ectomycorrhizal root colonization oak.

Mycorrhizas are known to have a pos. impact on plant growth and ability to resist major biotic and abiotic stresses. However, the metabolic alterations underlying mycorrhizal symbiosis are still understudied. By using metabolomics and transcriptomics approaches, cork oak roots colonized by the ectomycorrhizal fungus Pisolithus tinctorius were compared with non-colonized roots. Results show that compounds putatively corresponding to carbohydrates, organic acids, tannins, long-chain fatty acids and monoacylglycerols, were depleted in ectomycorrhizal cork oak colonized roots. Conversely, non-proteogenic amino acids, such as gamma-aminobutyric acid (GABA), and several putative defense-related compounds, including oxylipin-family compounds, terpenoids and B6 vitamers were induced in mycorrhizal roots. Transcriptomic anal. suggests the involvement of GABA in ectomycorrhizal symbiosis through increased synthesis and inhibition of degradation in mycorrhizal roots. Results from this global metabolomics anal. suggest decreases in root metabolites which are common components of exudates, and in compounds related to root external protective layers which could facilitate plant-fungal contact and enhance symbiosis. Root metabolic pathways involved in defense against stress were induced in ectomycorrhizal roots that could be involved in a plant mechanism to avoid uncontrolled growth of the fungal symbiont in the root apoplast. Several of the identified symbiosis-specific metabolites, such as GABA, may help to understand how ectomycorrhizal fungi such as P. tinctorius benefit their host plants.

Scientific Reports published new progress about Alkaloids Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Computed Properties of 492-62-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Teruel, Adrian H.; Perez-Esteve, Edgar; Gonzalez-Alvarez, Isabel; Gonzalez-Alvarez, Marta; Costero, Ana M.; Ferri, Daniel; Gavina, Pablo; Merino, Virginia; Martinez-Manez, Ramon; Sancenon, Felix published the artcile< Double Drug Delivery Using Capped Mesoporous Silica Microparticles for the Effective Treatment of Inflammatory Bowel Disease>, Safety of Sodium 5,5′-(diazene-1,2-diyl)bis(2-hydroxybenzoate), the main research area is silica microparticle hydrocortisone inflammatory bowel disease antiinflammatory; colon targeted release; gated materials; inflammatory bowel disease; mesoporous silica microparticles; smart drug delivery materials.

Silica mesoporous microparticles loaded with both rhodamine B fluorophore (S1) or hydrocortisone (S2), and capped with an olsalazine derivative, are prepared and fully characterized. Suspensions of S1 and S2 in water at an acidic and a neutral pH show negligible dye/drug release, yet a notable delivery took place when the reducing agent sodium dithionite is added because of hydrolysis of an azo bond in the capping ensemble. Addnl., olsalazine fragmentation induced 5-aminosalicylic acid (5-ASA) release. In vitro digestion models show that S1 and S2 solids are suitable systems to specifically release a pharmaceutical agent in the colon. In vivo pharmacokinetic studies in rats show a preferential rhodamine B release from S1 in the colon. Moreover, a model of ulcerative colitis is induced in rats by oral administration of 2,4,6-trinitrobenzenesulfonic acid (TNBS) solutions, which was also used to prove the efficacy of S2 for colitis treatment. The specific delivery of hydrocortisone and 5-ASA from S2 material to the colon tissue in injured rats markedly lowers the colon/body weight ratio and the clin. activity score. Histol. studies showed a remarkable reduction in inflammation, as well as an intensive regeneration of the affected tissues.

Molecular Pharmaceutics published new progress about Anti-inflammatory agents. 6054-98-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C14H8N2Na2O6, Safety of Sodium 5,5′-(diazene-1,2-diyl)bis(2-hydroxybenzoate).

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Liu, Jiahao; Li, Weikang; Li, Yinwu; Liu, Yan; Ke, Zhuofeng published the artcile< Selective C-alkylation between Alcohols Catalyzed by N-Heterocyclic Carbene Molybdenum>, Reference of 403-41-8, the main research area is primary secondary alc molybdenum complex alkylation chemoselectivity green chem; secondary alc preparation; Alcohols; Alkylation; Borrowing hydrogen; Molybdenum catalysis; N-heterocyclic carbene.

The implementation of a molybdenum complex with an easily accessible bis-N-heterocyclic carbene ligand to catalyze β-alkylation of secondary alcs. via borrowing-hydrogen (BH) strategy using alcs. as alkylating agents was reported. Remarkably high activity, excellent selectivity and broad substrate scope compatibility with advantages of catalyst usage low to 0.5 mol%, a catalytic amount of NaOH as the base and H2O as the byproduct were demonstrated in this green and step-economical protocol. Mechanistic studies indicated a plausible outer-sphere mechanism in which the alc. dehydrogenation is the rate-determining step.

Chemistry – An Asian Journal published new progress about Alkylation catalysts (chemoselective). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Reference of 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Murgia, Denise; Mauceri, Rodolfo; Campisi, Giuseppina; De Caro, Viviana published the artcile< Advance on resveratrol application in bone regeneration: progress and perspectives for use in oral and maxillofacial surgery>, Safety of (E)-5-(4-Hydroxystyryl)benzene-1,3-diol, the main research area is review resveratrol chronic bone regeneration surgery; Resveratrol; alveolar bone loss; bone defect; bone-regeneration; craniofacial tissue; resveratrol scaffold.

A review of the natural polyphenol Resveratrol (RSV) claims numerous pos. effects on health due to the well documented biol. effects demonstrating its potential as a disease-preventing agent and as adjuvant for treatment of a wide variety of chronic diseases. Since several studies, both in vitro and in vivo, have highlighted the protective bone aptitude of RSV both as promoter of osteoblasts’ proliferation and antagonist of osteoclasts’ differentiation, they could be interesting in view of applications in the field of dentistry and maxillofacial surgery. This review has brought together exptl. findings on the use of RSV in the regeneration of bone tissue comprising also its application associated with scaffolds and non-transfusional hemocomponents.

Biomolecules published new progress about Bone. 501-36-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C14H12O3, Safety of (E)-5-(4-Hydroxystyryl)benzene-1,3-diol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Slominski, Andrzej T.; Chaiprasongsuk, Anyamanee; Janjetovic, Zorica; Kim, Tae-Kang; Stefan, Joanna; Slominski, Radomir M.; Hanumanthu, Vidya Sagar; Raman, Chander; Qayyum, Shariq; Song, Yuwei; Song, Yuhua; Panich, Uraiwan; Crossman, David K.; Athar, Mohammad; Holick, Michael F.; Jetten, Anton M.; Zmijewski, Michal A.; Zmijewski, Jaroslaw; Tuckey, Robert C. published the artcile< Photoprotective Properties of Vitamin D and Lumisterol Hydroxyderivatives>, Quality Control of 434-16-2, the main research area is vitamin D lumisterol hydroxyderivative photoprotective property review; DNA damage; Lumisterol; Oxidative stress; Skin; Ultraviolet B; Vitamin D.

A review. Abstract: We have previously described new pathways of vitamin D3 activation by CYP11A1 to produce a variety of metabolites including 20(OH)D3 and 20,23(OH)2D3. These can be further hydroxylated by CYP27B1 to produce their C1α-hydroxyderivatives. CYP11A1 similarly initiates the metabolism of lumisterol (L3) through sequential hydroxylation of the side chain to produce 20(OH)L3, 22(OH)L3, 20,22(OH)2L3 and 24(OH)L3. CYP11A1 also acts on 7-dehydrocholesterol (7DHC) producing 22(OH)7DHC, 20,22(OH)27DHC and 7-dehydropregnenolone (7DHP) which can be converted to the D3 and L3 configurations following exposure to UVB. These CYP11A1-derived compounds are produced in vivo and are biol. active displaying anti-proliferative, anti-inflammatory, anti-cancer and pro-differentiation properties. Since the protective role of the classical form of vitamin D3 (1,25(OH)2D3) against UVB-induced damage is recognized, we recently tested whether novel CYP11A1-derived D3- and L3-hydroxyderivatives protect against UVB-induced damage in epidermal human keratinocytes and melanocytes. We found that along with 1,25(OH)2D3, CYP11A1-derived D3-hydroxyderivatives and L3 and its hydroxyderivatives exert photoprotective effects. These included induction of intracellular free radical scavenging and attenuation and repair of DNA damage. The protection of human keratinocytes against DNA damage included the activation of the NRF2-regulated antioxidant response, p53-phosphorylation and its translocation to the nucleus, and DNA repair induction. These data indicate that novel derivatives of vitamin D3 and lumisterol are promising photoprotective agents. However, detailed mechanisms of action, and the involvement of specific nuclear receptors, other vitamin D binding proteins or mitochondria, remain to be established.

Cell Biochemistry and Biophysics published new progress about Absorption Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 434-16-2 belongs to class alcohols-buliding-blocks, and the molecular formula is C27H44O, Quality Control of 434-16-2.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts