Month: February 2023

Synthesis of Cu(II) aminoalkoxide complexes and their unusual thermolysis to Cu(0) was written by Park, Jung Woo;Jang, Hong Suk;Kim, Minchan;Sung, Kiwhan;Lee, Sun Sook;Chung, Taek-Mo;Koo, Sangman;Kim, Chang Gyoun;Kim, Yunsoo. And the article was included in Inorganic Chemistry Communications in 2004.Formula: C6H15NO This article mentions the following:

The F free Cu(II) aminoalkoxide complexes Cu(OCMe₂CH₂NR₂)₂ (R = Me(I), Et(II)) were synthesized and characterized as a low melting solid (I) and a viscous liquid (II). The complexes are thermally decomposed at <200° to produce metallic Cu by unusual γ-H elimination reaction. In the experiment, the researchers used many compounds, for example, 1-(Dimethylamino)-2-methylpropan-2-ol (cas: 14123-48-9Formula: C6H15NO).

1-(Dimethylamino)-2-methylpropan-2-ol (cas: 14123-48-9) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Formula: C6H15NO

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Iridium-Catalyzed Branch-Selective and Enantioselective Hydroalkenylation of α-Olefins through C-H Cleavage of Enamides was written by Sun, Xin;Lin, En-Ze;Li, Bi-Jie. And the article was included in Journal of the American Chemical Society in 2022.Name: (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol This article mentions the following:

Catalytic branch-selective hydrofunctionalization of feedstock α-olefins to form enantioenriched chiral compounds is a particularly attractive yet challenging transformation in asym. catalysis. Herein, an iridium-catalyzed asym. hydroalkenylation of α-olefins through directed C-H cleavage of enamides was reported. This atom-economical addition process is highly branch-selective and enantioselective, delivering trisubstituted alkenes with an allylic stereocenter. DFT calculations reveal the origin of regio- and enantioselectivity. In the experiment, the researchers used many compounds, for example, (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5Name: (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol).

(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Name: (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Site-Selective 1,2-Dicarbofunctionalization of Vinyl Boronates through Dual Catalysis was written by Sun, Shang-Zheng;Duan, Yaya;Mega, Riccardo S.;Somerville, Rosie J.;Martin, Ruben. And the article was included in Angewandte Chemie, International Edition in 2020.Application In Synthesis of 2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane This article mentions the following:

A modular, site-selective photochem. 1,2-dicarbofunctionalization of vinyl boronate CH₂:CHBpin with organic halides RBr and ArBr through dual catalysis afforded double addition products RCH₂CHAr(Bpin) (4a–t; R = ^tBu, tertiary alkyl, cycloalkyl; Ar = substituted Ph, naphthyl). This reaction proceeds under mild conditions and is characterized by excellent chemo- and regioselectivity. It thus represents a complementary new technique for preparing densely functionalized alkyl boron architectures from simple and accessible precursors. In the experiment, the researchers used many compounds, for example, 2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 68716-49-4Application In Synthesis of 2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane).

2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 68716-49-4) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Application In Synthesis of 2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Strategy of solution process precursors for phase change memory was written by Hwang, Jeong Min;Lee, Ji Hun;Kim, Hyo-Suk;Park, Chan Woo;Yoo, Dagyum;Park, Bo Keun;Kim, Chang Gyoun;Chung, Taek-Mo. And the article was included in Polyhedron in 2020.Formula: C6H15NO This article mentions the following:

The relation between the steric hindrance of the alpha carbon substituent group of aminoalkoxy ligand and formation of germanium telluride (GeTe) and antimony telluride (Sb₂Te₃) was elucidated. Germanium and antimony precursors were prepared using aminoalkoxide-type bidentate ligands of different sizes such as dmampH, dmapH and dmaeH. These precursor materials were further treated with bis(trimethylsilyl)telluride in hexadecane through thermal reaction and studied with powder x-ray diffraction (pXRD) to compare the formation of germanium telluride (GeTe) and antimony telluride (Sb₂Te₃) alloys which are potential precursor materials for phase change random access memory devices. While the pXRD patterns of the thermal reaction materials of compounds 2 and 3 at 190° revealed a rhombohedral phase of GeTe and tellurium, compounds 5 and 6 at 190° showed a rhombohedral phase of Sb₂Te₃ and tellurium at this temperature Probably the formation of chalcogenide alloys was more favorable when relatively less bulk ligand was used. In the experiment, the researchers used many compounds, for example, 1-(Dimethylamino)-2-methylpropan-2-ol (cas: 14123-48-9Formula: C6H15NO).

1-(Dimethylamino)-2-methylpropan-2-ol (cas: 14123-48-9) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Formula: C6H15NO

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Protocol for the analyzing of terpin hydrate in a multi-component sugar coated tablet named Pectol D by GC was written by Ha, Minh Hien;Tran, Thi Bich Ha;Bo, Nguyen Thuy Duoung. And the article was included in Tap Chi Duoc Hoc in 2006.Name: rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate This article mentions the following:

Anal. of terpin hydrate in multi-component sugar coated tablets namely Pectol D by UV-Vis method was not possible due to the interference of excipients. Alternatively, a GC method using a packed column of 50% di-Me 50% di-Ph polysiloxane was suggested and validated based on ASEAN Guidelines for Validation of Anal. Procedures. The method was proved to be accurate, precise and sufficiently selective. In the experiment, the researchers used many compounds, for example, rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6Name: rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate).

rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Name: rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Palladium-catalyzed Heck cyclization/carbonylation with formates: synthesis of azaindoline-3-acetates and furoazaindolines was written by Ye, Hao;Wu, Linhui;Zhang, Minrui;Jiang, Guomin;Dai, Hong;Wu, Xin-Xing. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2022.Application In Synthesis of Benzo[d][1,3]dioxol-4-ol This article mentions the following:

Herein a palladium-catalyzed domino cyclization/carbonylation to access ester-functionalized azaindolines, e.g., I applying formates, e.g., phenylformate as a convenient carbonyl source was reported. All four azaindoline isomers were constructed, exhibiting good functional group compatibility. On this basis, modifying the starting tether on the aminopyridine led to furoazaindolines, e.g., II via an intramol. reductive cyclization after the palladium-catalyzed process. In the experiment, the researchers used many compounds, for example, Benzo[d][1,3]dioxol-4-ol (cas: 69393-72-2Application In Synthesis of Benzo[d][1,3]dioxol-4-ol).

Benzo[d][1,3]dioxol-4-ol (cas: 69393-72-2) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Application In Synthesis of Benzo[d][1,3]dioxol-4-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Manganese-Catalyzed Asymmetric Hydrosilylation of Aryl Ketones was written by Ma, Xiaochen;Zuo, Ziqing;Liu, Guixia;Huang, Zheng. And the article was included in ACS Omega in 2017.SDS of cas: 120121-01-9 This article mentions the following:

Nonracemic (oxazolinyl)pyridinylimine manganese complexes I (R = i-Pr, Ph₂CH; R¹ = H, Me; R² = PhCH₂, i-Pr, t-Bu) were prepared as catalysts for the enantioselective hydrosilylation of aralkyl ketones. In the presence of I (R = Ph₂CH; R¹ = Me; R² = t-Bu), aralkyl ketones such as 4-R³C₆H₄COMe (R³ = Cl, i-Bu, t-Bu, cyclohexyl, n-Pr, MeO, Br, I, H) with Ph₃SiH and NaBHEt₃ in toluene to yield nonracemic benzylic alcs. such as (R)-4-R³C₆H₄CH(OH)Me (R³ = Cl, i-Bu, t-Bu, cyclohexyl, n-Pr, MeO, Br, I, H) in 48-99% yields and 66:34-96.5:3.5 er. The structure of I·2 CH₂Cl₂ (R = Ph₂CH; R¹ = Me; R² = t-Bu) was determined by X-ray crystallog. In the experiment, the researchers used many compounds, for example, (R)-1-(3-Chlorophenyl)ethanol (cas: 120121-01-9SDS of cas: 120121-01-9).

(R)-1-(3-Chlorophenyl)ethanol (cas: 120121-01-9) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.SDS of cas: 120121-01-9

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Regulation of mechanical properties of diene rubber cured by oxa-Michael Reaction via manipulating network structure was written by Zhang, Xuhui;Tang, Zhenghai;Guo, Baochun. And the article was included in Polymer in 2018.Recommanded Product: 4074-88-8 This article mentions the following:

As diene rubber products are generally fabricated with complicated curing package involving toxic additives, the exploration of alternative green curing chem. for diene rubber is of great importance. In this contribution, we demonstrate a curing chem. based on oxa-Michael reaction for diene rubber to achieve the combination of simple curing system and tunable mech. properties. Specifically, pendent hydroxyls are introduced onto the solution-polymerized styrene-butadiene rubber (SSBR) via thiol-ene click reaction and the modified SSBR is effectively cured by various acrylates without the use of any addnl. additives. The mech. behaviors of vulcanizates can be widely regulated by manipulating the network structures, which is tuned by curing temperature, hydroxyl content of SSBR, content and functionality of acrylates. The correlation between mech. properties and network structure is accordingly achieved, which provides essential basis for the future application of the diene rubbers cured by oxa-Michael reaction. In the experiment, the researchers used many compounds, for example, Diethyleneglycoldiacrylate (cas: 4074-88-8Recommanded Product: 4074-88-8).

Diethyleneglycoldiacrylate (cas: 4074-88-8) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Recommanded Product: 4074-88-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Physical constants of substituted acetophenones was written by Guzman-Lopez, Enrique;Rosas, Noe;Walls, Fernando. And the article was included in Boletin del Instituto de Quimica de la Universidad Nacional Autonoma de Mexico in 1970.Quality Control of 2′,6′-Dihydroxy-4′-methylacetophenone This article mentions the following:

An attempt to prepare perezone and the 2 pipitzols gave a mixture of 2-(4-methyl-2,5-dimethoxyphenyl)-6-methyl-1,5-heptadiene and 2-(4-methyl-2,5-dimethoxyphenyl)-6-methyl-2,5-heptadiene, and 12 substituted acetophenones, and 5 related products. Their ir, uv, and NMR spectra were described. In the experiment, the researchers used many compounds, for example, 2′,6′-Dihydroxy-4′-methylacetophenone (cas: 1634-34-0Quality Control of 2′,6′-Dihydroxy-4′-methylacetophenone).

2′,6′-Dihydroxy-4′-methylacetophenone (cas: 1634-34-0) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Quality Control of 2′,6′-Dihydroxy-4′-methylacetophenone

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Effect of synthesis conditions on the non-uniformity of nanofiltration membrane pore size distribution was written by Zhang, Ting;Fu, Ruo-Yu;Wang, Kun-Peng;Gao, Ya-Wei;Li, Hong-Rui;Wang, Xiao-Mao;Xie, Yuefeng F.;Hou, Li’an. And the article was included in Journal of Membrane Science in 2022.SDS of cas: 149-32-6 This article mentions the following:

The uniformity of membrane pore sizes, which is essentially determined by the membrane synthesis conditions, significantly affects the rejection performance of nanofiltration (NF) membranes. In this study, we applied two modeling methods, i.e., the DSPM (Donnan Steric Pore Model) and the log-normal distribution methods, for the determination of the average membrane pore size and pore size uniformity of lab-made NF membranes. The synthesis conditions included concentration of monomers (e.g., piperazine and trimesoyl chloride), (thermal) curing temperature and time, and activation solvent type and duration. Results showed that both high piperazine (PIP) concentration (≥0.5 wt%) and curing temperature (≥40°C) could enhance the membrane pore size uniformity. Although the average membrane pore size calculated by the DSPM method was higher than that by the log-normal distribution method, they significantly correlated. It appears that the log-normal distribution method could more directly characterize membrane pore size uniformity. Obviously, the pore uniformity of NF membranes affected the rejection of small mols., such as trace organic compounds These insights provided a theor. foundation for the characterization of membrane pore size distribution with more accuracy and the fabrication of membranes with higher pore size uniformity. In the experiment, the researchers used many compounds, for example, (2R,3S)-rel-Butane-1,2,3,4-tetraol (cas: 149-32-6SDS of cas: 149-32-6).

(2R,3S)-rel-Butane-1,2,3,4-tetraol (cas: 149-32-6) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.SDS of cas: 149-32-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts