Month: December 2022

Direct formation of oxetanes by pyrolysis of diprimary diols in the presence of catalysts was written by Jaubert, Michele;Mazet, Michel;Yvernault, Theophile. And the article was included in Bulletin de la Societe Chimique de France in 1974.Application of 115-84-4 The following contents are mentioned in the article:

Oxetanes I (R = Et, Pr, Bu, CHMe2, H, Me; R1 = H, Me, Et, Pr, Bu, CHMe2, CMe3, CHPrMe, CHPrEt, (CH2)4Me) were prepared in ≤24% yield by pyrolyzing RR1C(CH2OH)2, the acetals II, or the formals III in the presence of pumice at 350°. A pumice-diol ratio of 5 gave the highest yields. The yields of I also increased with the size of R and R1. Pyrolysis of I (R = R1 = Et) gave Et2CHCHO, Et2C:CH2, EtPrCHCHO, EtMeCHCOEt, PrMeCHCOMe. This study involved multiple reactions and reactants, such as 2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4Application of 115-84-4).

2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Application of 115-84-4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

A convenient biphasic process for the monosilylation of symmetrical 1,n-primary diols was written by Yu, Chengzhi;Liu, Bin;Hu, Longqin. And the article was included in Tetrahedron Letters in 2000.SDS of cas: 115-84-4 The following contents are mentioned in the article:

A simple and mild biphasic process was developed for the selective protection of one of two chem. equivalent primary hydroxyl groups in 1,n-diols using t-butyldiphenyl silyl chloride in diisopropyl Et amine (DIEA) and DMF. E.g., a solution of 2-Butyl-2-ethylpropanediol in DMF (3 mL) was charged with DIEA (10 equiv), to which mixture was added TBDPSCl (1.05 equiv) with stirring to give the corresponding monosilylated product in 92% yield. This study involved multiple reactions and reactants, such as 2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4SDS of cas: 115-84-4).

2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.SDS of cas: 115-84-4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synthesis of high-boiling water resistance polyester used for outdoor powder coatings was written by Cao, Yongyi;Chen, Guomin. And the article was included in Guangdong Huagong in 2015.Name: 2-Butyl-2-ethylpropane-1,3-diol The following contents are mentioned in the article:

The paper modifies the polyester resin which is used for general outdoor engineering with 2-ethyl-2-butyl-1, 3-propanediol (BEPD) as monomer, discuss the effect of BEPD to the glass transition temperature, viscosity, boiling water resistance, weathering resistance and mech. behavior of coatings. By the means of adjust the branching degree, use amount of catalyzer, the prepared resin has nice boiling water resistance and weather resistance. This study involved multiple reactions and reactants, such as 2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4Name: 2-Butyl-2-ethylpropane-1,3-diol).

2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Name: 2-Butyl-2-ethylpropane-1,3-diol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Anionic Amphiphilic Cyclodextrins Bearing Oleic Grafts for the Stabilization of Ruthenium Nanoparticles Efficient in Aqueous Catalytic Hydrogenation was written by Cocq, Aurelien;Leger, Bastien;Noel, Sebastien;Bricout, Herve;Djedaini-Pilard, Florence;Tilloy, Sebastien;Monflier, Eric. And the article was included in ChemCatChem in 2020.Name: 3,7-Dimethyloctan-1-ol The following contents are mentioned in the article:

Oleic succinyl β-cyclodextrin was proved to be efficient for the stabilization of ruthenium nanoparticles (NPs) in aqueous medium. The catalytic activity of these NPs was evaluated in the aqueous hydrogenation of petrosourced and biosourced unsaturated compounds such as benzene and furfural derivatives The catalytic system can be easily recycled and reused up to nine runs without any loss of activity and selectivity, demonstrating its robustness. This study involved multiple reactions and reactants, such as 3,7-Dimethyloctan-1-ol (cas: 106-21-8Name: 3,7-Dimethyloctan-1-ol).

3,7-Dimethyloctan-1-ol (cas: 106-21-8) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Name: 3,7-Dimethyloctan-1-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Development of chiral catalysts by asymmetric activation for highly enantioselective diethylzinc addition to imines was written by Zhang, Hai-Le;Liu, Hua;Cui, Xin;Mi, Ai-Qiao;Jiang, Yao-Zhong;Gong, Liu-Zhu. And the article was included in Synlett in 2005.Reference of 851615-07-1 The following contents are mentioned in the article:

Based on the asym. activation concept, a library of chiral zinc complexes formed in situ by the combination of diimines derived from chiral 1,2-diphenyl-ethanene-1,2-diamine, BINOL derivatives, and diethylzinc are evaluated in the asym. addition of diethylzinc to N-acylimines. In the presence of 10 mol% catalyst I high enantioselectivities and yields were provided for a wide range of aromatic imines in 1,2-dichloroethane at -25 °C. This study involved multiple reactions and reactants, such as (R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol (cas: 851615-07-1Reference of 851615-07-1).

(R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol (cas: 851615-07-1) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Reference of 851615-07-1

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Structure determination and formation mechanism of procyanidin B2 oxidation products was written by Suwa, Yudai;Yanase, Emiko. And the article was included in Tetrahedron in 2022.Product Details of 29106-49-8 The following contents are mentioned in the article:

Procyanidins B2 and B1 were chem. oxidized to clarify the chem. changes in procyanidins upon oxidation Four compounds were structurally determined and could be produced using different oxidation methods, including enzymic oxidation with polyphenol oxidase. In the case of procyanidin B2, the different ratios of oxidized products formed in water compared with organic solvents are attributed to the procyanidin solvent-dependent conformational differences. This study involved multiple reactions and reactants, such as (2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol (cas: 29106-49-8Product Details of 29106-49-8).

(2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol (cas: 29106-49-8) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Product Details of 29106-49-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Continuous flow Reductive Alkylation of Methanol by Aldehydes. Synthesis of O-Methyl Ethers and 1,1-Dimethoxyacetals was written by Radjagobalou, Robbie;Rouffeteau, Virgile;Deleu, Alexia;Nabokoff, Pierre;Cossy, Janine;Len, Christophe. And the article was included in Molecular Catalysis in 2022.Application In Synthesis of 3,7-Dimethyloctan-1-ol The following contents are mentioned in the article:

A mild and efficient continuous-flow catalytic reductive alkylation of methanol by various linear and branched aliphatic aldehydes, at 140°C, using a Pd/C cartridge (1 wt% – 5 wt%) under 1 bar of hydrogen, was developed to produce O-Me ethers in high yields and tolyl derivatives from aryl aldehydes. When the pourcentage of Pd/C was lower than 1 wt%, 1,1-dimethoxyacetals were obtained from aldehydes. To rationalize these results, a mechanism was proposed. This study involved multiple reactions and reactants, such as 3,7-Dimethyloctan-1-ol (cas: 106-21-8Application In Synthesis of 3,7-Dimethyloctan-1-ol).

3,7-Dimethyloctan-1-ol (cas: 106-21-8) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Application In Synthesis of 3,7-Dimethyloctan-1-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

New 1-hetarylfuropyridines and chromenes based on pyridoxal and 4-hydroxycoumarin was written by Trifonov, Alexey V.;Kibardina, Lyudmila K.;Dobrynin, Alexey B.;Akhunov, Amirjon A. Ali;Pudovik, Mikhail A.;Burilov, Alexander R.. And the article was included in Mendeleev Communications in 2020.Electric Literature of C8H10ClNO3 The following contents are mentioned in the article:

Pyridoxal in the absence of a catalyst forms furo[3,4-c]pyridine species (ortho aldehyde and hydroxymethyl groups were involved) which is further transformed into C-C hybrid with 4-hydroxycoumarin. Different products of chromeno[3′,4′:5,6]pyrano[2,3-c]pyridine type were formed when pyridoxal hydrochloride or more sophisticated 2,4-dihydroxybenzaldehyde derivative were applied (herein, ortho aldehyde and hydroxy groups were involved into heterocyclization). This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Electric Literature of C8H10ClNO3).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Electric Literature of C8H10ClNO3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synthesis of Deuterated (E)-Alkene through Xanthate-Mediated Hydrogen-Deuterium Exchange Reactions was written by Li, Jiaming;Li, Jian;Ji, Xiaoliang;He, Runfa;Liu, Yang;Chen, Zebin;Huang, Yubing;Liu, Qiang;Li, Yibiao. And the article was included in Organic Letters in 2021.Safety of (2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol The following contents are mentioned in the article:

A reversible hydrogen-deuterium exchange reaction of nonactivated olefins was reported. By using EtOCS₂K as a mediator, the H/D exchange reaction was realized through repeated addition and elimination reactions, demonstrating reversible H/D exchange between ordinary olefins and deuterated olefins. Using the lowest cost D₂O without precious metal catalysts and ligands, a broad spectrum of compatibility of functional groups was achieved. This study involved multiple reactions and reactants, such as (2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (cas: 27208-80-6Safety of (2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol).

(2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (cas: 27208-80-6) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Safety of (2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Novel Axially Chiral Ligand-Enabled Copper-Catalyzed Asymmetric Oxidative Coupling of 2-Naphthols for the Synthesis of 6,6′-Disubstituted BINOLs was written by Wang, Pengyang;Cen, Shouyi;Gao, Jun;Shen, Ahui;Zhang, Zhipeng. And the article was included in Organic Letters in 2022.Computed Properties of C40H26O2 The following contents are mentioned in the article:

Novel axially chiral ligands such as I [R = H, 1-naphthyl, 9-anthryl, etc.] were designed and synthesized by merging the chelating picolinic acid with substituted BINOLs. The in-situ-prepared copper catalysts from the ligands and CuI enable the asym. oxidative coupling of 2-naphthols, affording 6,6′-disubstituted BINOLs such as II [R¹ = H, i-Pr, Ph, etc.] in up to 89% yield with good enantioselectivities (up to 96:4 e.r.). This study involved multiple reactions and reactants, such as (R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol (cas: 851615-07-1Computed Properties of C40H26O2).

(R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol (cas: 851615-07-1) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Computed Properties of C40H26O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts