Month: December 2022

Zhang, Kai published the artcileClinical Significance of Galactose-Deficient IgA1 by KM55 in Patients with IgA Nephropathy, Related Products of alcohols-buliding-blocks, the main research area is IgA1 KM55 monoclonal antibody diagnosis IgA nephropathy; Complement activation; Galactose-deficient IgA1; IgA nephropathy; KM55 antibody.

Background: Aberrant galactose-deficient IgA1 mols. (Gd-IgA1) are important causal factors in IgA nephropathy (IgAN); however, the detection of Gd-IgA1 in IgAN is complicated and instable. A monoclonal antibody, KM55, which specifically recognizes Gd-IgA1 has been developed. In the present study, we further explored the clin. significance of Gd-IgA1 using KM55. Methods: In this study, we enrolled 75 patients with IgAN and 80 healthy controls and detected the plasma Gd-IgA1 levels using the KM55 ELISA method. We also stained -mesangial Gd-IgA1 deposition using KM55. Results: We observed that the levels of plasma Gd-IgA1 in IgAN patients were elevated compared to the corresponding levels of healthy controls. Patients were divided into 2 groups based on the median of Gd-IgA1. Patients with high Gd-IgA1 levels had significantly higher levels of uric acid (UA) and IgA. The other clin. manifestations demonstrated that there were no differences in age, sex, blood pressure, initial proteinuria, hematuria, estimated glomerular filtration rate and Oxford pathol. classification between the 2 groups of patients. In addition, pos. correlations were observed between Gd-IgA1 and Bb, C3a, C4d and MAC. Mesangial Gd-IgA1 was pos. in IgAN but neg. in the normal renal tissue adjacent to neoplasm. We next analyzed the correlation between plasma Gd-IgA1 and mesangial Gd-IgA1 deposition. The results showed that a high level of plasma Gd-IgA1 was related to the deposition of mesangial Gd-IgA1, although the difference was not significant. Conclusion: We verified the elevated level of plasma and -mesangial Gd-IgA1 in patients with IgAN by KM55, which provided an alternative, easy, and reliable tool for diagnosis and activity assessment of IgAN. The level of plasma Gd-IgA1 pos. correlated with levels of UA, total IgA levels, and complement activation products.

Kidney & Blood Pressure Research published new progress about Age groups. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Sciukaite, Agne published the artcileContents of some bioactive compounds in Norway spruce needles as affected by short-term storage at different conditions and implications for their industrial use, Safety of rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, the main research area is Norway spruce needle bioactive compound.

The main aim of the research was to evaluate changes in contents of essential oils and pigments in Norway spruce needles as affected by short-term storage under different conditions as well as to assess the potential resources of winter-harvested foliage obtainable from byproducts of forest felling as a natural source of these bioactives. One- and two-year-old needles were taken for the analyses fresh (control) and after five-week storage at three different conditions: at 4°C in fridge, at -24°C in freezer and in the forest of their origin. Essential oils were isolated from needles by hydrodistillation and analyzed by gas chromatog.-mass spectrometry. Analyses of chlorophylls and carotenoids were performed spectrophotometrically. The study showed that none of the tested storage conditions of P. abies needles had significant influence on the total amounts of essential oils in them varying from 0.16% to 0.20% per dry matter (v/w) in two- and one-year-old needles, resp. Bornyl acetate was the main compound identified in the essential oils amounting to 14.47-40.04%. The mean total contents of chlorophylls amounted to 1.10 mg/g in one-year-old needles and to 1.28 mg/g in two-year-old ones measured in fresh weight Statistically significant differences were established in the levels of all the pigments analyzed between fresh material, and stored under controlled, -24°C and 4°C, conditions both of 1-yr-old and 2-yr-old needles. The highest contents of the pigments were obtained after the storage at 4°C as well as under the natural forest condition. Based on the above data and the national forestry statistics, potential yields of essential oils (6.45 kg), total chlorophylls (9.27 kg) and total carotenoids (1.32 kg) were assessed per ha of a mature sprucewood stand in Lithuania.

Industrial Crops and Products published new progress about Age groups. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Safety of rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Pakrieva, Ekaterina published the artcileSupported gold nanoparticles as catalysts in peroxidative and aerobic oxidation of 1-phenylethanol under mild conditions, Recommanded Product: n-Octanol, the main research area is gold nanoparticle phenylethanol peroxidative aerobic oxidation; 1-phenylethanol; DFT; TBHP; alcohol oxidation; gold; heterogeneous catalysis.

The efficiency of Au/TiO2 based catalysts in 1-phenylethanol oxidation was investigated. The role of support modifiers (La2O3 or CeO2), influence of gold loading (0.5% or 4%) and redox pretreatment atm., catalyst recyclability, effect of oxidant, (tert-Bu hydroperoxide (TBHP) or O2), as well as the optimization of exptl. parameters of the reaction conditions in the oxidation of this alc. were studied and compared with previous studies on 1-octanol oxidation Samples were characterized by temperature-programmed oxygen desorption (O2-TPD) method. XPS measurements were carried out for used catalysts to find out the reason for deactivation in 1-phenylethanol oxidation The best catalytic characteristics were shown by catalysts modified with La2O3, regardless of the alc. and the type of oxidant. When O2 was used, the catalysts with 0.5% Au, after oxidative pretreatment, showed the highest activity in both reactions. The most active catalysts in 1-phenylethanol oxidation with TBHP were those with 4% Au and the H2 treatment, while under the same reaction conditions, 0.5% Au and O2 treatment were beneficial in 1-octanol oxidation Despite the different chem. nature of the substrates, it seems likely that Au+(Auδ+) act as the active sites in both oxidative reactions. D. functional theory (DFT) simulations confirmed that the gold cationic sites play an essential role in 1-phenylethanol adsorption.

Nanomaterials published new progress about Adsorption. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Recommanded Product: n-Octanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wu, Ke published the artcileA humidity sensor based on ionic liquid modified metal organic frameworks for low humidity detection, Safety of Pentaerythritol tetra(3-mercaptopropionate), the main research area is ionic liquid metal organic framework polyelectrolyte humidity sensor stability.

Low humidity detection has always been a challenge in the field of humidity detection. Humidity sensors base on ionic liquid modified metal organic frameworks (MOFs) derived polymer films were prepared in this work. The ionic liquid ligand was uniformly introduced in the frameworks of UIO-66 to enhance the hydrophilicity of sensing materials, the caused defects sites are beneficial for adsorption and desorption, and the MOFs based functional films were easily obtained by in situ photoinduced thiol-ene click reaction. The obtained humidity sensor exhibits a linear response in low relative humidity (RH) range (5% RH – 30% RH) with a tiny humidity hysteresis (∼0.2% RH) and short response time to humidity change (response/recovery time is 0.6 s/1.7 s, resp.).

Sensors and Actuators, B: Chemical published new progress about Adsorption. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Safety of Pentaerythritol tetra(3-mercaptopropionate).

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Aili published the artcileControllable click synthesis of poly(ionic liquid)s by surfactant-free ionic liquid microemulsions for selective dyes reduction, Computed Properties of 7575-23-7, the main research area is surfactant free polyionic liquid preparation dye reduction property.

This work reveals the synthesis of poly(ionic liquid)s (poly-ILs) with controllable beading network structure. The synthesis route involved the formation of novel surfactant-free ionic liquid microemulsions and the in situ photo-initiated thiol-ene “”click”” reaction. Notably, the beading size of poly-IL’s networks was adjusted by altering the component proportion of the designed surfactant-free ionic liquid microemulsion. To characterize the as-prepared polymers, FTIR, DLS, NMR, TGA, DSC, SEM and UV-vis were used, and the adsorption isotherm/kinetics studies were carried out. The results show that poly-ILs exhibit distinct adsorption selectivity and high adsorption capacity for nonionic dye disperse red (1080 mg/g), and these dye absorption polymers can be easily regenerated and recycled without a significant decrease. Therefore, the designed poly-ILs indicate remarkable potential in the application of dying wastewater treatment.

Reactive & Functional Polymers published new progress about Adsorption. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Computed Properties of 7575-23-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Psillakis, Elefteria published the artcileVacuum-assisted headspace single-drop microextraction: Eliminating interfacial gas-phase limitations, Application of n-Octanol, the main research area is vacuum headspace single drop microextraction interfacial gas phase limitation; Analyte evaporation; Analyte uptake; Gas constraints; Headspace single drop microextraction; Reduced pressure; Vacuum-assisted headspace single drop microextraction.

Gas-phase limitations have been neglected in headspace single-drop microextraction (HS-SDME) and rate control has been assumed to primarily reside in the liquid water and/or organic phases, but not in the headspace. Herein we demonstrate the presence of interfacial gas constraints and propose using reduced headspace pressures to remove them. To describe the pressure dependence of HS-SDME, the system was decoupled into two interfacial steps: (i) the evaporation step (water-headspace interface) formulated using the two-film theory and (ii) the analyte uptake by the microdrop (headspace-microdrop interface) formulated using the resistance model. Naphthalene, acenaphthene, and pyrene were chosen as model analytes for their large Henry’s law solubility constants in n-octanol (HOA > 103 M atm-1), and their low to moderate Henry’s law volatility constants in water as a solvent (KH). We have found that extraction times were significantly shortened for all analytes by sampling at pressures well below the 1 atm used in the standard HS-SDME procedure. The acceleration of naphthalene extraction, whose facile evaporation into the headspace had been assumed to be practically pressure independent, highlighted the role of mass transfer through the interfacial gas layer on the organic solvent drop. The larger accelerations observed for acenaphthene and (especially) pyrene upon reducing the sampling pressure, suggested that gas-sided constraints were important during both the evaporation and uptake steps. Model calculations incorporating mass transfers at the headspace-microdrop interface confirmed that gas-phase resistance is largely eliminated (>96%) when reducing the sampling pressure from 1 to 0.04 atm, an effect that is nearly independent of analyte mol. mass. The relative importance of the two interfacial steps and their gas- and liquid-phase limitations are discussed, next to the use of KH and HOA to predict the pos. effect of vacuum on HS-SDME.

Analytica Chimica Acta published new progress about Adsorption. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Application of n-Octanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Xin, Qingping published the artcileLight-responsive metal-organic framework sheets constructed smart membranes with tunable transport channels for efficient gas separation, Application In Synthesis of 97-67-6, the main research area is light metal organic framework sheet membrane gas separation.

Exploring a new type of smart membrane with tunable separation performance is a promising area of research. In this study, new light-responsive metal-organic framework [Co(azpy)] sheets were prepared by a facile microwave method for the first time, and were then incorporated into a polymer matrix to fabricate smart mixed matrix membranes (MMMs) applied for flue gas desulfurization and decarburization. The smart MMMs exhibited significantly elevated SO2(CO2)/N2 selectivity by 184(166)% in comparison with an unfilled polymer membrane. The light-responsive characteristic of the smart MMMs was investigated, and the permeability and selectivity of the Co(azpy) sheets-loaded smart MMMs were able to respond to external light stimuli. In particular, the selectivity of the smart MMM at the Co(azpy) content of 20% for the SO2/N2 system could be switched between 341 and 211 in situ irradiated with Vis and UV light, while the SO2 permeability switched between 58 Barrer and 36 Barrer, resp. This switching influence was mainly ascribed to the increased SO2 adsorption capacity in the visible light condition, as verified by adsorption test. The CO2 permeability and CO2/N2 selectivity of MMMs in the humidified state could achieve 248 Barrer and 103.2, surpassing the Robeson′s upper bound reported in 2019.

RSC Advances published new progress about Adsorption. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Application In Synthesis of 97-67-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Du, Cheng published the artcileDirect Surface Modification of Graphitic C3N4 with Porous Organic Polymer and Silver Nanoparticles for Promoting CO2 Conversion, COA of Formula: C8H14O, the main research area is surface graphitic carbon nitride porous organic polymer silver nanoparticle.

The development of novel heterogeneous catalysts for converting CO2 into fine chems. under mild conditions is extremely attractive but challenging. In this study, graphitic carbon nitride modified by porous organic polymer (POP) and highly dispersed Ag nanoparticles (Ag/POP@g-C3N4) was prepared as a highly efficient heterogeneous catalyst for CO2 conversion for the first time. The POP modifying g-C3N4 remarkably increases sp. surface area and nitrogen species (N-H and C=N); as a result, the abundant porous structures together with anchoring sites allow tight immobilization and homogeneous dispersion of Ag nanoparticles. Benefiting from the effective incorporation, Ag/POP@g-C3N4 exhibited superior catalytic performance for the carboxylative cyclization of propargyl alcs. with CO2 under mild conditions. From the perspective of CO2 adsorption and controlled 1H NMR analyses, a plausible synergistic catalytic mechanism was proposed for the adsorption and activation of CO2 in combination with Ag/POP@g-C3N4 and 1,8-diazabicyclo[5.4.0]undec-7-chin (DBU). Constructing a heterogeneous catalyst by surface modification was proposed to efficiently promote green and sustainable conversion of CO2 into fine chems.

ACS Sustainable Chemistry & Engineering published new progress about Adsorption. 107-54-0 belongs to class alcohols-buliding-blocks, name is 3,5-Dimethylhex-1-yn-3-ol, and the molecular formula is C8H14O, COA of Formula: C8H14O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhu, Kaili published the artcileOne-Pot Synthesis of Tensile-Strained PdRuCu Icosahedra toward Electrochemical Hydrogenation of Alkene, Computed Properties of 584-02-1, the main research area is alkene lead ruthenium copper icosahedra one pot synthesis.

Electrochem. hydrogenation (ECH) uses electricity to drive proton (H+) reduction for hydrogenation, which can greatly reduce energy supply and environmental pollution, representing an ideal alternative to traditional thermal hydrogenation. In this work, we put forward tensile-strained PdRuCu alloy to promote ECH. Tensile strain promotes the adsorption of C=C by changing the d-band center. Meanwhile, alloying Ru and Cu into Pd lattice facilitates hydrogenation by weakening Pd-H bonding. Therefore, PdRuCu icosahedra display excellent ECH performance of 2-methyl-3-buten-2-ol (MBE) with specific activity of 227.4μmolMBE nm-2 min-1 at -0.3 V vs. reversible hydrogen electrode (RHE), about 16.1 and 10.5 times higher than that of com. Pd/C and Ru/C, resp. In addition, PdRuCu icosahedra was excellent in the scaling up of substrate concentration combined with anisyl alc. oxidation to produce high-value added anisaldehyde at anode. This work provides a guideline for the rational design of highly active and durable metallic catalyst in ECH.

ChemElectroChem published new progress about Adsorption. 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Computed Properties of 584-02-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Santibanez, Luis published the artcileCuII- and CoII-based MOFs: {[La2Cu3(μ-H2O)(ODA)6(H2O)3]·3H2O}n and {[La2Co3(ODA)6(H2O)6]·12H2O}n. The relevance of physicochemical properties on the catalytic aerobic oxidation of cyclohexene, Application In Synthesis of 110-99-6, the main research area is lanthanum copper cobalt cyclohexene catalytic aerobic oxidation pore size.

The aerobic oxidation of cyclohexene was done using the heterometallic metal organic frameworks (MOFs) {[La2Cu3(μ-H2O)(ODA)6(H2O)3]·3H2O}n and {[La2Co3(ODA)6(H2O)6]·12H2O}n (LaCoODA) (2) as catalysts, in solvent free conditions (ODA, oxydiacetic acid). After 24 h of reaction, the catalytic system showed that LaCoODA had a better catalytic performance than that of LaCuODA (conversion 85% and 67%). The structures of both catalysts were very similar, showing channels running along the c axis. The physicochem. properties of both MOFs were determined to understand the catalytic performance. The Langmuir surface area of LaCoODA was shown to be greater than that of LaCuODA, while the acid strength and acid sites were greater for LaCuODA. On the other hand, the redox potential of the active sites was related to CoII/CoIII in LaCoODA and CuII/CuI in LaCuODA. Therefore, it is concluded that the Langmuir surface area and the redox potentials were more important than the acid strength and acid sites of the studied MOFs, in terms of the referred catalytic performance. Finally, the reaction conditions were also shown to play an important role in the catalytic performance of the studied systems. Especially, the type of oxidant and the way to supply it to the reaction medium influenced the catalytic results.

Catalysts published new progress about Adsorption. 110-99-6 belongs to class alcohols-buliding-blocks, name is 2,2′-Oxydiacetic acid, and the molecular formula is C4H6O5, Application In Synthesis of 110-99-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts