Month: November 2022

The pro-apoptotic and cytotoxic efficacy of polydatin encapsulated poly(lactic-co-glycolic acid) (PLGA) nanoparticles was written by Vijayalakshmi, Sankaran;Rajasekar, Aruliah;Veeraraghavan, Vishnu Priya;Ghidan, Alaa Yousef;M. Al Antary, Tawfiq;Karthikkumar, Venkatachalam;Damodaran, Lakshmi Priya Malarveni;Vinayagam, Ramachandran;David, Ernest. And the article was included in Process Biochemistry (Oxford, United Kingdom) in 2021.Recommanded Product: 27208-80-6 The following contents are mentioned in the article:

Polydatin (POL) is an ingredient of many herbal medications and has pharmacol. properties. The present study aimed to determine the antitumor potential of Polydatin loaded poly(lactic-co-glycolic acid) (PLGA) nanoparticles (POL-PLGA-NPs) against the cancerous KB cell line. We evaluated the efficiency of synthesized nanoparticles on cell proliferation and apoptosis markers, in addition to the generation of reactive oxygen species (ROS) and its potential to induce damages on the mitochondrial membrane. Morphol. changes in the cells (damage to DNA incurred due to cell lysis) were observed under Ethidium Bromide and Acridine orange staining techniques. The results evidenced the loss of cell viability, increased ROS, altered lipid peroxidation levels, increased DNA damage and loss of mitochondrial membrane potential in target cancerous KB cells. Further, immunoblot anal. quantified the expression of caspases-3, -9 and poly(ADP-ribose) polymerase (PARP) also supports the cell damage. Thus, the findings of the study suggested that POL-PLGA-NPs effectively induced oxidative stress by initiating cellular damage leading to apoptosis in KB cells. This study involved multiple reactions and reactants, such as (2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (cas: 27208-80-6Recommanded Product: 27208-80-6).

(2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (cas: 27208-80-6) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Recommanded Product: 27208-80-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Evaluation of repellents against mosquitoes in Panama was written by Gilbert, I. H.;Gouck, H. K.. And the article was included in Florida Entomologist in 1955.Quality Control of 2-Butyl-2-ethylpropane-1,3-diol The following contents are mentioned in the article:

Protection time for skin applications of dimethyl phthalate (I) is 304 min. Protection time in min. for other compounds and mixtures is allyl mandelate 387; 1-(o-methoxyphenyl)-3-buten-1-ol 366; propyl mandelate 362; α-tert-butylpiperonyl alc. 361; o-ethoxy-N,N-diethylbenzamide (II) 356; N,N-diethyl-m-toluamide 349; amyl mandelate 344; N,N-diethyl-o-toluamide 332; dimethyl carbate (III) 318; 2-ethyl-1,3-hexanediol (IV) 313; propyl ester of N,N-diethylsuccinamic acid (V) 311; o-chloro-N,N-diethylbenzamide (VI) 308; 2-[2-(2-butoxyethoxy)ethoxy]ethyl senecioate 291; citral-malonic acid condensate Number 1 259; 60% I, 20% IV, and 20% indalone 328; 50% IV and 50% II 346; 40% I, 30% IV, and 30% V 325; 40% IV, 30% V, and 30% VI 318; 40% I, 30% IV, and 30% III 305; 16% I, 12% IV, 12% III, 10% ZnO, 10% Delta Prime (VII), 0.75% Veegum (VIII), 3% Span 80 (IX), 2% Tween 80 (X), and 34.25% H₂O 195; and 16% I, 12% IV, 12% III, 10% ZnO, 10% VII, 2.4% IX, 1.6% X, 0.25% VIII, 1.75% Pluronic F-68, and 34% H₂O 180. Addition of a few percent of α-cyano-2-furanacrylate to I and II of the above mixtures slightly increases protection time. This study involved multiple reactions and reactants, such as 2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4Quality Control of 2-Butyl-2-ethylpropane-1,3-diol).

2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Quality Control of 2-Butyl-2-ethylpropane-1,3-diol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Rational design of 2D ultrathin BiO(HCOO)_xI_1-x composite nanosheets: The synergistic effect of ultrathin structure and hybridization in the effective elimination of BPA under visible light irradiation was written by Wang, Qiao;Lv, Guanheng;Cao, Yiting;Chen, Zhenhui;Jia, Jialin;Qin, Yanlin;Lin, Zhenxuan;Xie, Xuan;Wang, Zhihong. And the article was included in Separation and Purification Technology in 2022.Safety of 4,4′-Methylenediphenol The following contents are mentioned in the article:

Here, a novel series of 2D bismuth oxide formate-x composites were first fabricated with a ultrathin thickness (∼2.47 nm). Among them, the optimal BiO(HCOO)_0.75I_0.25 nanosheets exhibited a superior photocatalytic performance with the kinetic constant reaching up to 0.2148 min-1, which was 5.9, 97.6 and 27.2 folds higher than that of pristine BiOI, BiOCOOH and BiO(HCOO)_0.75I_0.25-P nanoplates, resp. Benefiting from the synergistic effect of ultrathin two-dimensional structure and hybrid composite, the photocatalytic performance was signally improved. Based on the optical and photoelectrochem. characterizations, the fabrication of hybrid composite delivered the optimal balance of visible-light absorption and redox capacity, endowing the photoinduced holes a higher oxidation potential. Meanwhile, the construction of 2D ultrathin structure reduced the migration distance of charge carriers, consequently accelerated those separated rate. This study provides a new insight for designing high active Bi-based photocatalysts, which is hopeful to make a great contribution to aquatic environmental restoration. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Safety of 4,4′-Methylenediphenol).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Safety of 4,4′-Methylenediphenol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Pulsed electric fields (PEF), pressurized liquid extraction (PLE) and combined PEF + PLE process evaluation: Effects on Spirulina microstructure, biomolecules recovery and Triple TOF-LC-MS-MS polyphenol composition was written by Zhou, Jianjun;Wang, Min;Berrada, Houda;Zhu, Zhenzhou;Grimi, Nabil;Barba, Francisco J.. And the article was included in Innovative Food Science & Emerging Technologies in 2022.Quality Control of (2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol The following contents are mentioned in the article:

This study aims at evaluating the impact of different processes-pulsed elec. fields (PEF), pressurized liquid extraction (PLE) and a multistep process combining PEF + PLE on the yield of antioxidant compounds (protein, polyphenols, chlorophyll a, chlorophyll b, and carotenoids) from Spirulina. Firstly, the effects of PEF or PLE treatment on the extraction yield of Spirulina biomols. were evaluated. To further increase the extraction yield, PEF + PLE was used, as an innovative extraction approach. The results showed that PEF + PLE greatly improved the extraction yield compared with the PEF or PLE treatments alone. Compared with Folch extraction (conventional control technique), PEF + PLE significantly (P < 0.05) shortened the extraction time (-165 min) and increased the protein, polyphenol, chlorophyll a and antioxidant capacity values of Spirulina extracts by 1328%, 979%, 11% and 47% resp. Furthermore, Triple TOF-LC-MS-MS results showed that PEF + PLE increased both the type and content of phenolic compounds The above results were attributed to PEF-induced damage on Spirulina helical structure, which was verified by fluorescence and SEM. This study involved multiple reactions and reactants, such as (2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (cas: 27208-80-6Quality Control of (2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol).

(2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (cas: 27208-80-6) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Quality Control of (2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Can polydatin have a beneficial role against bisphenol an exposure in rats? was written by Aslan, Recep;Demirel, Hasan Huseyin;Avdatek, Fatih;Bulbul, Aziz;Eryavuz, Abdullah;Gulay, Mehmet Sukru. And the article was included in Songklanakarin Journal of Science and Technology in 2022.Recommanded Product: 27208-80-6 The following contents are mentioned in the article:

The present study was conducted to evaluate the effects of chronic bisphenol A (BPA) exposure and the possible protective effects of polydatin (PD) on different organs, oxidant-antioxidant status and spermatol. parameters in male Wistar rats. Male Wistar rats (2 to 3 mo old) were randomly divided into 5 groups (n = 6). Group 1 was the control (daily 0.5ml distilled water). Groups 2, 3, 4 and 5 daily received 0.5 mL olive oil (OO), 25 mg/kg bisphenol A in 0.5 olive oil (BPA), 150 mg/kg polydatin (PD), and a mixture of 25 mg/kg bisphenol A in 0.5 olive oil + 150 mg/kg polydatin (BPA-PD), resp., daily for 45 days. BPA had neg. effects on percent abnormal sperm and Hypo-osmotic swelling-Eosin (HE) test (P<0.01). BPA caused neg. histopathol. alterations to the brain, heart, liver, kidney, and testis tissues. PD administration was able to ameliorate the neg. effects of BPA. Moreover, PD had pos. effects on percent motility (P<0.02), head defects of sperm (P<0.01), and HE test (P<0.01) when compared to the controls. The results indicate that PD decreases BPA-induced sperm defects and repaired tissue damage in the various organs in rats. This study involved multiple reactions and reactants, such as (2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (cas: 27208-80-6Recommanded Product: 27208-80-6).

(2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (cas: 27208-80-6) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Recommanded Product: 27208-80-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Application of bacteriophage to develop indicator for Escherichia coli detection and modulation of its biochemical reaction to improve detection ability: A proof-of-concept study was written by Choi, Inyoung;Lee, Jung-Soo;Han, Jaejoon. And the article was included in Food Control in 2022.Electric Literature of C9H18O5S The following contents are mentioned in the article:

Bacteria indicators have been widely developed but still need complicated techniques, instruments, or well-trained users. This is a proof-of-concept study to develop a straightforward and colorimetric bacterial indicator using bacteriophages (phages) as bio-receptors and simple biochem. reactions for high sensitivity. Among the various phages, phage T4 with a high specificity to Escherichia coli was used. Hydrophilic polyvinyl alc. and trehalose were used as matrix polymers, and the optimal formulation ratio was examined to enhance the phage stability in the indicator matrix. Its sensitivity and detection rate were improved by investigating the interactions between phage T4 and iso-Pr β-D-thiogalactopyranoside. The final indicator showed high sensitivity detecting up to 10 CFU/mL after 11 h, even in the food application test such as drinking water and milk samples containing different fat contents. Although some challenges remain to satisfy the regulatory requirements for bacteria in foods and be applied to various foods, the introduced simple approach can pave the way to develop indicators to detect E. coli present in real food using phages. This study involved multiple reactions and reactants, such as (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1Electric Literature of C9H18O5S).

(2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Electric Literature of C9H18O5S

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Efficient Production of γ-GABA Using Recombinant E. coli Expressing Glutamate Decarboxylase (GAD) Derived from Eukaryote Saccharomyces cerevisiae was written by Xiong, Qiang;Xu, Zheng;Xu, Lu;Yao, Zhong;Li, Sha;Xu, Hong. And the article was included in Applied Biochemistry and Biotechnology in 2017.Recommanded Product: 65-22-5 The following contents are mentioned in the article:

γ-Aminobutyric acid (γ-GABA) is a non-proteinogenic amino acid, which acts as a major regulator in the central nervous system. Glutamate decarboxylase (namely GAD, EC 4.1.1.15) is known to be an ideal enzyme for γ-GABA production using L-glutamic acid as substrate. In this study, we cloned and expressed GAD gene from eukaryote Saccharomyces cerevisiae (ScGAD) in E. coli BL21(DE3). This enzyme was further purified and its optimal reaction temperature and pH were 37 °C and pH 4.2, resp. The cofactor of ScGAD was verified to be either pyridoxal 5′-phosphate (PLP) or pyridoxal hydrochloride. The optimal concentration of either cofactor was 50 mg/L. The optimal medium for E. coli-ScGAD cultivation and expression were 10 g/L lactose, 5 g/L glycerol, 20 g/L yeast extract, and 10 g/L sodium chloride, resulting in an activity of 55 U/mL medium, three times higher than that of using Luria-Bertani (LB) medium. The maximal concentration of γ-GABA was 245 g/L whereas L-glutamic acid was near completely converted. These findings provided us a good example for bio-production of γ-GABA using recombinant E. coli expressing a GAD enzyme derived from eukaryote. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Recommanded Product: 65-22-5).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Recommanded Product: 65-22-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Integrative analysis of transcriptome and metabolome reveals the mechanism of foliar application of Bacillus amyloliquefaciens to improve summer tea quality (Camellia sinensis) was written by Huang, Xiangxiang;Tang, Qian;Li, Qin;Lin, Haiyan;Li, Juan;Zhu, Mingzhi;Liu, Zhonghua;Wang, Kunbo. And the article was included in Plant Physiology and Biochemistry in 2022.Product Details of 29106-49-8 The following contents are mentioned in the article:

Bacillus amyloliquefaciens is a promising microbial agent for quality improvement in crops; however, the effects of B. amyloliquefaciens biofertilizers on tea leaf metabolites are relatively unknown. Herein, a combination of metabolome profiling and transcriptome anal. was employed to investigate the effects of foliar spraying with B. amyloliquefaciens biofertilizers on tea leaf quality. The tea polyphenol to amino acid ratio (TP/AA), catechin, and caffeine levels decreased, but theanine level increased in tea leaves after foliar spraying with B. amyloliquefaciens. The differentially accumulated metabolites included flavonoids, phenolic acids, organic acids, amino acids, and carbohydrates. The decrease in catechin was correlated with the catechin/flavonoid biosynthesis pathway. The AMPD gene was highly associated with caffeine content, while the GOGAT gene was associated with theanine accumulation. Foliar spraying with B. amyloliquefaciens biofertilizers may improve summer tea quality. Our findings provide a basis for the application of B. amyloliquefaciens biofertilizers in tea plants and new insights on summer tea leaf resource utilization. This study involved multiple reactions and reactants, such as (2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol (cas: 29106-49-8Product Details of 29106-49-8).

(2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol (cas: 29106-49-8) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Product Details of 29106-49-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Novel Tdp1 inhibitors based on adamantane connected with monoterpene moieties via heterocyclic fragments was written by Munkuev, Aldar A.;Mozhaitsev, Evgenii S.;Chepanova, Arina A.;Suslov, Evgeniy V.;Korchagina, Dina V.;Zakharova, Olga D.;Ilina, Ekaterina S.;Dyrkheeva, Nadezhda S.;Zakharenko, Alexandra L.;Reynisson, Johannes;Volcho, Konstantin P.;Salakhutdinov, Nariman F.;Lavrik, Olga I.. And the article was included in Molecules in 2021.SDS of cas: 106-21-8 The following contents are mentioned in the article:

Tyrosyl-DNA phosphodiesterase 1 (Tdp1) is a promising target for anticancer therapy due to its ability to counter the effects topoisomerase 1 (Top1) poison, such as topotecan, thus, decreasing their efficacy. Compounds containing adamantane and monoterpenoid residues connected via 1,2,4-triazole or 1,3,4-thiadiazole linkers were synthesized and tested against Tdp1. All the derivatives exhibited inhibition at low micromolar or nanomolar concentrations with the most potent inhibitors having IC₅₀ values in the 0.35-0.57 μM range. The cytotoxicity was determined in the HeLa, HCT-116 and SW837 cancer cell lines; moderate CC₅₀ (μM) values were seen from the mid-teens to no effect at 100 μM. Furthermore, citral derivative 20c, α-pinene-derived compounds 20f, 20g and 25c, and the citronellic acid derivative 25b were found to have a sensitizing effect in conjunction with topotecan in the HeLa cervical cancer and colon adenocarcinoma HCT-116 cell lines. The ligands are predicted to bind in the catalytic pocket of Tdp1 and have favorable physicochem. properties for further development as a potential adjunct therapy with Top1 poisons. This study involved multiple reactions and reactants, such as 3,7-Dimethyloctan-1-ol (cas: 106-21-8SDS of cas: 106-21-8).

3,7-Dimethyloctan-1-ol (cas: 106-21-8) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.SDS of cas: 106-21-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Comprehensive analysis of antibacterial and anti-hepatoma activity of metabolites from jujube fruit was written by Shi, Qianqian;Li, Xi;Zhu, Dajun;Jiang, Junjun;Li, Xingang. And the article was included in Food Bioscience in 2022.Application of 29106-49-8 The following contents are mentioned in the article:

Jujube is one of the most produced dried fruits in China, and it is also a traditional Chinese medicine that enhances immunity and has anti-cancer activity. Jujube fruit is rich in phenolic compounds, but few reports are available on its biol. activities. To evaluate the biol. activities of the phenolic compounds in dried jujube fruit, the composition and content of metabolites in dried jujube fruit were determined by metabolomics, and the antibacterial and anticancer activities of the phenolic compounds were analyzed in dried jujube fruit. The results showed that 463 compounds were identified in dried ′Junzao′ fruit, including 102 phenolic compounds The in vitro activity test showed that the jujube phenolic metabolites had extensive antibacterial effects and caused disruption and nuclear sclerosis of hepatocellular carcinoma (HepG2) cells. Canonical correlation anal. showed that total phenolic content, quercetin-3-rutinose, and procyanidin B1 were the main active antibacterial and anticancer components. The study provides data supporting the application of dried jujube fruit in the development of functional foods, pharmaceuticals and cosmetics. This study involved multiple reactions and reactants, such as (2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol (cas: 29106-49-8Application of 29106-49-8).

(2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol (cas: 29106-49-8) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Application of 29106-49-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts