Month: November 2022

Pierce, Cason; Keniston, Angela; Albert, Richard K published an article in 2019, the title of the article was Imaging in Acute Pyelonephritis: Utilization, Findings, and Effect on Management..Electric Literature of 78-26-2 And the article contains the following content:

OBJECTIVES: To determine the frequency, timing, and types of imaging obtained in patients with a discharge diagnosis of acute pyelonephritis, and how often imaging findings affect therapy. METHODS: This was a retrospective chart review of 1062 adults with a diagnosis of acute pyelonephritis discharged from an urban, safety-net hospital between January 1, 2008 and December 31, 2012. From the 739 patients selected after exclusions, we determined the number and proportion of patients imaged within the first 24 hours of admission, stratified by risk factors for pyelonephritis complications, and the frequency of positive findings leading to invasive interventions. RESULTS: Of 739 patients, 468 (63%) were imaged within 24 hours of admission, 262/414 (63%) of whom had risk factors for complications and 206/325 of whom (63%) did not. Among these, studies were positive in 117/468 (25%), 78/262 (30%) in those with risk factors, and 39/206 (19%) of those without risk factors. Of the 117 patients with positive imaging findings within 24 hours of admission, 58 (50%) underwent invasive procedures, 47 (60%) with risk factors and 11 (28%) without. Among all of the patients, interventions were directed at relieving obstructions much more commonly than treating abscess (51 patients vs 8). CONCLUSIONS: Among this population, imaging is frequently done earlier than recommended. Because the majority of interventions targeted stone disease, ultrasound may be the preferred initial modality rather than contrasted tomography when obtaining imaging early. Current guidelines may need to be revisited. The experimental process involved the reaction of 2-Methyl-2-propylpropane-1,3-diol(cas: 78-26-2).Electric Literature of 78-26-2

The Article related to acute disease, adolescent, adult, aged, aged, 80 and over, disease management, emergency service, hospital, female, hospitalization: statistics & numerical data, humans, male, middle aged, pyelonephritis: diagnosis, pyelonephritis: therapy, retrospective studies, risk factors, tomography, x-ray computed: statistics & numerical data and other aspects.Electric Literature of 78-26-2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On February 7, 2022, Cao, Yuefeng; Fan, Xiangming published an article.Electric Literature of 78-26-2 The title of the article was Surgical Repair of Secondary Subaortic Stenosis in Congenital Heart Disease Without Initial Subaortic Obstruction.. And the article contained the following:

BACKGROUND: Secondary subaortic stenosis (SSS) is a rare heart disease of the left ventricular outflow tract (LVOT). It usually occurs after cardiovascular correction with or without initial left ventricular outflow tract obstruction (LVOTO). Because most patients with SSS are asymptomatic, many do not realize the need for reoperation until the obstruction worsens. Few studies suggest the characteristics and reasons of SSS without initial SAS. We conducted a retrospective study to describe the characteristics and surgical outcomes of these patients. METHODS: In this study, we examined a single-center retrospective cohort of SSS patients without initial SAS undergoing resection from 2010 to 2019. Patients are defined as secondary subaortic obstruction requiring surgery after cardiovascular correction. Demographics, perioperative findings, and clinical data were analyzed. RESULTS: Twenty-three patients had undergone secondary cardiac surgery for SSS without initial SAS during 10 years in our center. The median age at operation was 7.3 (4.0-13.5) years. In this study, the most commonly associated cardiac lesions were ventricular septal defect (VSD), atrioventricular septal defect (AVSD), patent ductus arteriosus (PDA), and coarctation arch hypoplasia (COA). The surgical techniques included membranous resection of five patients, fibromuscular resection of 17 patients, and reconstruction of the intraventricular baffle of one patient. The results of surgery in these patients are satisfied. The average LVOT gradient at the last follow up was 14.9 (7.8-26.2) mmHg. There was no operative mortality. Two patients had postoperative complications. The median follow-up period was 2.9 (1.1-4.3) years with one late death. Two patients (8.7%) had recurrence of stenosis. CONCLUSIONS: Secondary subaortic stenosis is an uncommon heart disease. The reason is related to several causes, including missed diagnosis, unnoticed abnormalities of LVOT, and further changes of geometric morphology by intracardiac surgery. The results of surgery in these patients are satisfied. However, the recurrence of stenosis is still frequent. The experimental process involved the reaction of 2-Methyl-2-propylpropane-1,3-diol(cas: 78-26-2).Electric Literature of 78-26-2

The Article related to aortic stenosis, subvalvular: complications, aortic stenosis, subvalvular: diagnosis, aortic stenosis, subvalvular: surgery, constriction, pathologic: surgery, heart defects, congenital: complications, heart defects, congenital: diagnosis, heart defects, congenital: surgery, heart septal defects: surgery, humans, infant, reoperation and other aspects.Electric Literature of 78-26-2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On March 31, 2020, Ben Harb, Marwa; Abubshait, Samar; Etteyeb, Naceur; Kamoun, Madiha; Dhouib, Adnene published an article.Category: alcohols-buliding-blocks The title of the article was Olive leaf extract as a green corrosion inhibitor of reinforced concrete contaminated with seawater. And the article contained the following:

In reinforced concrete, a high alk. medium, steel is commonly protected by formation a passive oxide film. Nevertheless, contamination with chlorides or carbonation causes the deterioration of protective film and the initiation of pitting corrosion. Hence, the need to enrich the fresh concrete solution with a good corrosion inhibitor. In accordance with green chem. to evade toxicity and minimize waste, we have chosen to replace the usual inhibitors with an alternative not only ecol. but also derived from biol. wastes, in a perspective of circular economy emphasizing that waste can offer important compounds at an affordable price and easily available. In this context this work seeks to valorize the dried olive leaves extract as an inhibitor in alk. chloride solution (pH 13). The targeted plant was grown in arid zones of Saudi Arabia and their leaves are usually disposed of as solid waste or animal feed. Four extraction solvents of different polarities were used; methanol, Et acetate, dichloromethane and hexane. The anticorrosive activity was performed using different electrochem. techniques; polarization curves, electrochem. impedance spectroscopy and Mott-Schottky analyses. The polarization studies proved that extract from olive leaves is a mixed type inhibitor in a solution of NaOH (0.1 M) + NaCl (0.5 M),with a predominant anodic effectiveness. The best inhibition of 91.9% is provided with methanol extract GC-MS anal. showed the presence of compounds containing the heteroatoms N and O with the 蟺 electrons which are responsible for the corrosion inhibition activity. The olive leaves have been found to be high in phenol and flavonoid content. Inhibition efficiency of the olive leaves extracts increases with the polarity of extraction solvents but also it appears that it depends on another factors. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).Category: alcohols-buliding-blocks

The Article related to olea leaf green corrosion inhibitor reinforced concrete seawater contamination, biodegradation, carbonation, current density, flavonoids role: tem (technical or engineered material use), uses (uses), leaf, olea europaea, olive, oxidation, ph, phenols role: tem (technical or engineered material use), uses (uses), pitting corrosion, reinforced concrete, solubility and other aspects.Category: alcohols-buliding-blocks

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On June 4, 2019, Godlewski, Grzegorz; Cinar, Resat; Coffey, Nathan J.; Liu, Jie; Jourdan, Tony; Mukhopadhyay, Bani; Chedester, Lee; Liu, Ziyi; Osei-Hyiaman, Douglas; Iyer, Malliga R.; Park, Joshua K.; Smith, Roy G.; Iwakura, Hiroshi; Kunos, George published an article.Safety of H-Phg(4-OH)-OH The title of the article was Targeting Peripheral CB1 Receptors Reduces Ethanol Intake via a Gut-Brain Axis. And the article contained the following:

Endocannabinoids acting on the cannabinoid-1 receptor (CB1R) or ghrelin acting on its receptor (GHS-R1A) both promote alc.-seeking behavior, but an interaction between the two signaling systems has not been explored. Here, we report that the peripheral CB1R inverse agonist JD5037 reduces ethanol drinking in wild-type mice but not in mice lacking CB1R, ghrelin peptide or GHS-R1A. JD5037 treatment of alc.-drinking mice inhibits the formation of biol. active octanoyl-ghrelin without affecting its inactive precursor desacyl-ghrelin. In ghrelin-producing stomach cells, JD5037 reduced the level of the substrate octanoyl-carnitine generated from palmitoyl-carnitine by increasing fatty acid 尾-oxidation Blocking gastric vagal afferents abrogated the ability of either CB1R or GHS-R1A blockade to reduce ethanol drinking. We conclude that blocking CB1R in ghrelin-producing cells reduces alc. drinking by inhibiting the formation of active ghrelin and its signaling via gastric vagal afferents. Thus, peripheral CB1R blockade may have therapeutic potential in the treatment of alcoholism. The experimental process involved the reaction of H-Phg(4-OH)-OH(cas: 32462-30-9).Safety of H-Phg(4-OH)-OH

The Article related to behavior role: bsu (biological study, unclassified), biol (biological study), body weight role: bsu (biological study, unclassified), biol (biological study), signal transduction role: bsu (biological study, unclassified), biol (biological study), 尾-oxidation role: bsu (biological study, unclassified), biol (biological study), and other aspects.Safety of H-Phg(4-OH)-OH

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On February 1, 2021, Zhong, Shifa; Zhang, Kai; Wang, Dong; Zhang, Huichun published an article.Computed Properties of 111-29-5 The title of the article was Shedding light on “Black Box” machine learning models for predicting the reactivity of HO路 radicals toward organic compounds. And the article contained the following:

Developing quant. structure-activity relationships (QSARs) is an important approach to predicting the reactivity of HO radicals toward newly emerged organic compounds However, it is yet unknown whether this method makes predictions by choosing meaningful structural features rather than spurious ones, which is vital for trusting the models. In this study, we developed QSAR models for the logkHO路 values of 1089 organic compounds in the aqueous phase by two ML algorithms-deep neural networks (DNN) and eXtreme Gradient Boosting (XGBoost), and interpreted the built models by the SHapley Additive exPlanations (SHAP) method. The results showed that for the contribution of a given structural feature to logkHO. for different compounds, DNN and XGBoost treated it as a fixed and variable value, resp. We then developed an ensemble model combining the DNN with XGBoost, which achieved satisfactory predictive performance for all three datasets: Training dataset: R-square (R2) 0.89-0.91, root-mean-squared-error (RMSE) 0.21-0.23, and mean absolute error (MAE) 0.15-0.17; Validation dataset: R2 0.63-0.78, RMSE 0.29-0.32, and MAE 0.21-0.25; and Test dataset: R2 0.60-0.71, RMSE 0.30-0.35, and MAE 0.23-0.25. This study offered some much-needed mechanistic insights into a ML-assisted environmental task, which are important for evaluating the trustworthiness of the ML-based models, further improving the models for specific applications, and leveraging the implicit knowledge the models carry. The experimental process involved the reaction of Pentane-1,5-diol(cas: 111-29-5).Computed Properties of 111-29-5

The Article related to black box machine learning model radical organic compound, Water: Analysis and other aspects.Computed Properties of 111-29-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On March 31, 2020, Xie, Wenping; Zhao, Jiangang; Zhang, Qiyuan; Ye, Changpeng; Zheng, Guangming; Shan, Qi; Li, Lichun; Shao, Xiaofeng published an article.Recommanded Product: 2,4-Di-tert-butylphenol The title of the article was Occurrence, distribution and bioaccumulation of alkylphenols in the Pearl River networks, South China. And the article contained the following:

The concentrations and distributions of selected alkylphenols (APs; 4-nonylphenols, 4-n-octylphenol, 4-tert-octylphenol, 4-tert-butylphenol and 2,4-di-tert-butylphenol) in water, sediment and aquatic organism samples in the Pearl River networks were determined using gas chromatog.-mass spectrometry. The results showed that 4-nonylphenols (NPs) were dominant in both water samples and sediment samples. For APs, downtown and populated regions showed higher concentrations than rural regions; furthermore, the concentrations of APs in eastern tributaries were higher than those in western tributaries. In aquatic organism samples, the content range of APs, NPs, and octylphenols (OPs; 4-n-octylphenol and 4-tert-octylphenol) were 174.74-648.10 ng/g, 143.95-582.51 ng/g, and 8.10-37.10 ng/g, resp., with mean values of 346.52, 281.90, and 24.13 ng/g, accordingly. The accumulated level of APs in nine different species of aquatic organism species declined as follows: perch (Lateolabrax japonicus) > bighead fish (Aristichthys nobilis) > silver carp (Hypophthalmichthys molitrix) > carp (Cyprinus carpio) > barbel chub (Squaliobarbus curriculus) > shellfish (Corbicula fluminea) > grass carp (Ctenopharyngodon idellus) > cyprinid fish (Megalobrama hoffmanni) > shrimp (Macrobranchium nipponense). Carnivorous and filter-feeding fish tended to accumulate more APs than other dietic fish, shellfish and shrimps. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).Recommanded Product: 2,4-Di-tert-butylphenol

The Article related to alkylphenol bioaccumulation occurrence aquatic ecosystem water pollution monitoring, Water: Analysis and other aspects.Recommanded Product: 2,4-Di-tert-butylphenol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Sugiyama, Fuya; Iwamoto, Shinji published an article in 2020, the title of the article was Morphology and pore structure of zirconia particles preparedby the thermal treatment of zirconium tetra-n-propoxide in glycols.Category: alcohols-buliding-blocks And the article contains the following content:

Zirconia particles were prepared by thermal treatment of zirconium(IV) tetra-n-propoxide (ZNP) in C2-C6 glycols (Glycothermal method) at 300掳C and morphol. and pore structures of the products were examined Xray diffraction results revealed that nanocrystals of tetragonal zirconia phase were mainly obtained in all cases. However, the morphol. and pore structures of the products were quite different depending on the glycols used. The products prepared in 1,4-butanediol (1,4-BG) were spherical particles with ca. 5渭 m size while aggregations of fine particles were observed for other glycols. The samples obtained in 1,4-BG had large surface areas and showed narrow pore-size distributions in the mesopore region. To investigate the formation process of the products having such a unique morphol. and pore system, the mixtures of ZNP and glycols were heated at lower temperatures It was found that the thermal reaction of ZNP in 1,4-BG at 200掳C afforded intermediates with layered structures, which subsequently changed into nanocrystalline ZrO2 at elevated temperatures These stepwise crystallization processes attribute to the unique morphol. and pore system of the products obtained by the thermal treatment of ZNP in 1,4-BG. The experimental process involved the reaction of Pentane-1,5-diol(cas: 111-29-5).Category: alcohols-buliding-blocks

The Article related to zirconia tetra n propoxide glycol thermal treatment pore structure, Ceramics: Ceramics and other aspects.Category: alcohols-buliding-blocks

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ono, Kenjiro; Tsuji, Mayumi; Yamasaki, Tritia R.; Pasinetti, Giulio M. published an article in 2020, the title of the article was Anti-aggregation effects of phenolic compounds on 伪-synuclein.SDS of cas: 621-37-4 And the article contains the following content:

A review. The aggregation and deposition of 伪-synuclein (伪S) are major pathol. features of Parkinson’s disease, dementia with Lewy bodies, and other 伪-synucleinopathies. The propagation of 伪S pathol. in the brain plays a key role in the onset and progression of clin. phenotypes. Thus, there is increasing interest in developing strategies that attenuate 伪S aggregation and propagation. Based on cumulative evidence that 伪S oligomers are neurotoxic and critical species in the pathogenesis of 伪-synucleinopathies, we and other groups reported that phenolic compounds inhibit 伪S aggregation including oligomerization, thereby ameliorating 伪S oligomer-induced cellular and synaptic toxicities. Heterogeneity in gut microbiota may influence the efficacy of dietary polyphenol metabolism Our recent studies on the brain-penetrating polyphenolic acids 3-hydroxybenzoic acid (3-HBA), 3,4-dihydroxybenzoic acid (3,4-diHBA), and 3-hydroxyphenylacetic acid (3-HPPA), which are derived from gut microbiota-based metabolism of dietary polyphenols, demonstrated an in vitro ability to inhibit 伪S oligomerization and mediate aggregated 伪S-induced neurotoxicity. Addnl., 3-HPPA, 3,4-diHBA, 3-HBA, and 4-hydroxybenzoic acid significantly attenuated intracellular 伪S seeding aggregation in a cell-based system. This review focuses on recent research developments regarding neuroprotective properties, especially anti-伪S aggregation effects, of phenolic compounds and their metabolites by the gut microbiome, including our findings in the pathogenesis of 伪-synucleinopathies. The experimental process involved the reaction of 3-Hydroxyphenylacetic acid(cas: 621-37-4).SDS of cas: 621-37-4

The Article related to review phenolics anti aggregation alpha synuclein neurotoxicity, parkinson鈥檚 disease, gut microbiome, phenolic compounds, 伪-synuclein, Toxicology: Reviews and other aspects.SDS of cas: 621-37-4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts