Month: November 2022

The author of 《Location determination of metal nanoparticles relative to a metal-organic framework》 were Chen, Yu-Zhen; Gu, Bingchuan; Uchida, Takeyuki; Liu, Jiandang; Liu, Xianchun; Ye, Bang-Jiao; Xu, Qiang; Jiang, Hai-Long. And the article was published in Nature Communications in 2019. Formula: C7H7BrO The author mentioned the following in the article:

Metal nanoparticles (NPs) stabilized by metal-organic frameworks (MOFs) have been intensively studied in recent decades, while investigations on the location of guest metal NPs relative to host MOF particles remain challenging and very rare. In this work, we have developed several characterization techniques, including high-angle annular dark-field scanning transmission electron microscopy (HAADF-STEM) tomog., hyperpolarized 129Xe NMR spectroscopy and positron annihilation spectroscopy (PAS), which are able to determine the specific location of metal NPs relative to the MOF particle. The fine PdCu NPs confined inside MIL-101 exhibit excellent catalytic activity, absolute selectivity and satisfied recyclability in the aerobic oxidation of benzyl alc. in pure water. As far as we know, the determination for the location of metal NPs relative to MOF particles and pore structure information of metal NPs/MOF composites by 129Xe NMR and PAS techniques has not yet been reported. In the experiment, the researchers used many compounds, for example, (4-Bromophenyl)methanol(cas: 873-75-6Formula: C7H7BrO)

(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.Formula: C7H7BrO It is used in the synthesis of amphiphilic, symmetric rod-coil, triblock copolymer of poly(9,9-didodecylfluorene-2,7-diyl) and poly(hydroxyl ethyl methacrylate)

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

銆奊raphene layers functionalized with a Janus pyrrole-based compound in natural rubber nanocomposites with improved ultimate and fracture properties銆?was written by Prioglio, Gea; Agnelli, Silvia; Conzatti, Lucia; Balasooriya, Winoj; Schrittesser, Bernd; Galimberti, Maurizio. Application In Synthesis of 2-Aminopropane-1,3-diol And the article was included in Polymers (Basel, Switzerland) in 2020. The article conveys some information:

The ultimate properties and resistance to fracture of nanocomposites based on poly(1,4-cis-isoprene) from Hevea Brasiliensis (natural rubber, NR) and a high surface area nanosized graphite (HSAG) were improved by using HSAG functionalized with 2-(2,5-dimethyl-1H-pyrrol-1-yl)propane-1,3-diol (serinol pyrrole) (HSAG-SP). The functionalization reaction occurred through a domino process, by simply mixing HSAG and serinol pyrrole and heating at 180掳C. The polarity of HSAG-SP allowed its dispersion in NR latex and the isolation of NR/HSAG-SP masterbatches via coagulation. Nanocomposites, based either on pristine HSAG or on HSAG-SP, were prepared through traditional melt blending and cured with a sulfur-based system. The samples containing HSAG-SP revealed ultimate dispersion of the graphitic filler with smaller aggregates and higher amounts of few layers stacks and isolated layers, as revealed by transmission electron microscopy. With HSAG-SP, better stress and elongation at break and higher fracture resistance were obtained. Indeed, in the case of HSAG-SP-based composites, fracture occurred at larger deformation and with higher values of load and, at the highest filler content (24 phr), deviation of fracture propagation was observed These results have been obtained with a moderate functionalization of the graphene layers (about 5%) and normal lab facilities. This work reveals a simple and scalable way to prepare tougher NR-based nanocomposites and indicates that the dispersion of a graphitic material in a rubber matrix can be improved without using an extra-amount of mech. energy, just by modifying the chem. nature of the graphitic material through a sustainable process, avoiding the traditional complex approach, which implies oxidation to graphite oxide and subsequent partial reduction In the experimental materials used by the author, we found 2-Aminopropane-1,3-diol(cas: 534-03-2Application In Synthesis of 2-Aminopropane-1,3-diol)

2-Aminopropane-1,3-diol(cas: 534-03-2) belongs to anime.Typically the presence of an amine functional group is deduced by a combination of techniques, including mass spectrometry as well as NMR and IR spectroscopies. 1H NMR signals for amines disappear upon treatment of the sample with D2O. In their infrared spectrum primary amines exhibit two N-H bands, whereas secondary amines exhibit only one.Application In Synthesis of 2-Aminopropane-1,3-diol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Purt, G. published an article in 1962, the title of the article was The binary system BaO-WO3.Formula: C8H19NO2 And the article contains the following content:

With more than 40 samples of different compositions, the equilibrium diagram BaO-WO3 could be established, m.p. determinations and Debye-Scherrer pictures being used. Two congruently melting compounds appear, leading to 3 eutectics in the system. The experimental process involved the reaction of 2,2′-(tert-Butylazanediyl)diethanol(cas: 2160-93-2).Formula: C8H19NO2

2,2′-(tert-Butylazanediyl)diethanol(cas:2160-93-2) belongs to alcohols. In general, the hydroxyl group makes alcohols polar. Those groups can form hydrogen bonds to one another and to most other compounds. Owing to the presence of the polar OH alcohols are more water-soluble than simple hydrocarbons. Formula: C8H19NO2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On March 29, 1954, Zima, Otto; von Werder, Fritz published a patent.Category: alcohols-buliding-blocks The title of the patent was Choline derivatives. And the patent contained the following:

The compatibility of compounds ROCH2CH2NR12CH2SMe+X- is improved by oxidation of the thio to the sulfoxide group. To a solution of 30 g. dimethyl(尾-hydroxyethyl)(methylthiomethyl)ammonium chloride in 45 cc. water is added 22 g. 30% aqueous H2O2. The yield of dimethyl(尾-hydroxyethyl)(methylsulfinylmethyl)ammonium chloride is 28 g., m. 96掳, also prepared by oxidation of chloromethyl sulfide with H2O2 and condensation with dimethylaminoethanol. In a similar manner is prepared diethyl(尾-hydroxyethyl)(methylsulfinylmethyl)ammonium chloride, m. 126掳. The experimental process involved the reaction of 2-(Methylamino)ethan-1-ol hydrochloride(cas: 62640-03-3).Category: alcohols-buliding-blocks

2-(Methylamino)ethan-1-ol hydrochloride(cas:62640-03-3) belongs to alcohols. In general, the hydroxyl group makes alcohols polar. Those groups can form hydrogen bonds to one another and to most other compounds. Owing to the presence of the polar OH alcohols are more water-soluble than simple hydrocarbons. Category: alcohols-buliding-blocks

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On September 1, 2021, Maudhoo, Ashwini; Maharaj, Avinaash; Buonocore, Federica; Martos-Moreno, Gabriel Angel; Argente, Jes煤s; Achermann, John C; Chan, Li F; Metherell, Lou A published an article.COA of Formula: C7H16O2 The title of the article was Missplicing due to a synonymous, T96= exonic substitution in the T-box transcription factor TBX19 resulting in isolated ACTH deficiency.. And the article contained the following:

SUMMARY: Congenital isolated ACTH deficiency (IAD) is a rare condition characterised by low plasma ACTH and serum cortisol with normal production of other pituitary hormones. TBX19 (also known as TPIT) is a T-box pituitary restricted transcription factor important for POMC gene transcription and terminal differentiation of POMC-expressing cells. TBX19 gene mutations have been shown to cause neonatal-onset congenital IAD. We report a neonate of Romanian origin, who presented at 15 h of life with respiratory arrest and hypoglycaemia which recurred over the following 2 weeks. Biochemical investigations revealed IAD, with undetectable serum cortisol (cortisol < 1 渭g/dL; normal range (NR): 7.8-26.2) and plasma ACTH levels within the normal range (22.1 pg/mL; NR: 4.7-48.8). He responded to hydrocortisone treatment. Patient DNA was analysed by a HaloPlex next-generation sequencing array targeting genes for adrenal insufficiency. A novel homozygous synonymous mutation p.Thr96= (Chr1:168260482; c.288G>A; rs376493164; allele frequency 1 脳 10-5, no homozygous) was found in exon 2 of the TBX19 gene. The effect of this was assessed by an in vitro splicing assay, which revealed aberrant splicing of exon 2 giving rise to a mutant mRNA transcript whereas the WT vector spliced exon 2 normally. This was identified as the likely cause of IAD in the patient. The predicted protein product would be non-functional in keeping with the complete loss of cortisol production and early presentation in the patient. LEARNING POINTS: Synonymous variants (a nucleotide change that does not alter protein sequence) usually thought to be benign may still have detrimental effects on RNA and protein function causing disease. Hence, they should not be ignored, especially if very rare in public databases. In vitro splicing assays can be employed to characterise the consequence of intronic and exonic nucleotide gene changes that may alter splicing. Establishing a diagnosis due to a TBX19 mutation is important as it defines a condition of isolated ACTH deficiency not associated with additional pituitary deficiencies. The experimental process involved the reaction of 2-Methyl-2-propylpropane-1,3-diol(cas: 78-26-2).COA of Formula: C7H16O2

2-Methyl-2-propylpropane-1,3-diol(cas:78-26-2) belongs to alcohols. In general, the hydroxyl group makes alcohols polar. Those groups can form hydrogen bonds to one another and to most other compounds. Owing to the presence of the polar OH alcohols are more water-soluble than simple hydrocarbons. COA of Formula: C7H16O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Fishbein, Lawrence; Cavanaugh, M. A. published an article in 1965, the title of the article was Detection and paper chromatography of N-substituted hydroxy, 2-hydroxyethyl, 2-chloroethyl, and N,N-bis(2-hydroxyethyl) derivatives.Product Details of 2160-93-2 And the article contains the following content:

Studies of the metabolism, degradation, and mutagenicity of N-substituted 2-hydroxyethyl, and 2-chloroethyl pesticides, N-hydroxy carbamates and related N and C substituted OH derivatives prompted the need to evaluate various categories of detecting reagents as to their possible utility for subsequent differentiation, and identification of the above moieties in a variety of aliphatic, aromatic, and cyclic compounds One-dimensional descending chromatography was carried out on Whatman Number 1 filter paper by using the following solvent systems: BuOH-HOAc-H2O (5:1:4); BuOH-EtOH-H2O (7:1:2); and iso-PrOH-NH4OH-H2O (80:5:15). Detecting reagents were: (1) 5% Na nitroprusside-10% MeCHO mixed with an equal volume of 2% aqueous Na2CO3; (2) FCNP reagent (mixture of equal volumes of 10% NaOH, 10% Na nitroprusside, and 10% K ferricyanide diluted with 3 volumes of H2O, and mixed with an equal volume of Me2CO); (3) 0.2% ninhydrin in Me2CO; (4) 0.2% ninhydrin in Me2CO with 5% C5H5N; (5) 1% FeCl3 in MeOH; (6) 10% p-dimethylaminobenzaldehyde in 1:4 Me2CO-concentrated HCl; (7) 2 ml. trans-cinnamaldehyde in 95 ml. EtOH, 18.5 ml. H2O, and 6 ml. concentrated HCl; (8) 5% 4-(p-nitrobenzyl)pyridine in Me2CO; (9) 0.5% barbituric acid in EtOH containing 2 ml. 85% H3P4O (10) equal volumes of C5H5N and MeCHO; (11) 1% isatin in iso-PrOH containing 1% C5H5N and 1.5% Zn(OAc)2; (12) 0.5% Cu(OAc)2 in EtOH containing 0.1% Me2NH and 2% (HOC2H4)3N; (13) 0.5 % 2,6-dibromo-N-chloro-p-quinone imine in 4:1 dioxane-Me2CO; (14) 5% N,2,6-trichlorobenzoquinone imine in 4:1 dioxane-Me2CO; (15) 3% K nitrosodisulfonate in N NaOH; (16) 1% KMnO4. The Rf values and color of spots with the reagents are given for 76 N and C substituted N-hydroxy, 2-hydroxyethyl, 2-chloroethyl, and N,N-bis(2-hydroxyethyl) derivatives and related compounds The experimental process involved the reaction of 2,2′-(tert-Butylazanediyl)diethanol(cas: 2160-93-2).Product Details of 2160-93-2

2,2′-(tert-Butylazanediyl)diethanol(cas:2160-93-2) belongs to alcohols. In general, the hydroxyl group makes alcohols polar. Those groups can form hydrogen bonds to one another and to most other compounds. Owing to the presence of the polar OH alcohols are more water-soluble than simple hydrocarbons. Product Details of 2160-93-2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Liteanu, C.; Gocan, S. published an article in 1961, the title of the article was Paper thermochromatography. I. Separation of the mixture Cu++ and Cd++ with butanol + HCl.Category: alcohols-buliding-blocks And the article contains the following content:

Rf values change as the temperature gradient increases. Changes in Rf values for Cd++ and Cu++ are different in 80% butanol + 3N 20% HCl, so that better separation is obtained. The experimental process involved the reaction of 2,2′-(tert-Butylazanediyl)diethanol(cas: 2160-93-2).Category: alcohols-buliding-blocks

2,2′-(tert-Butylazanediyl)diethanol(cas:2160-93-2) belongs to alcohols. In general, the hydroxyl group makes alcohols polar. Those groups can form hydrogen bonds to one another and to most other compounds. Owing to the presence of the polar OH alcohols are more water-soluble than simple hydrocarbons. Category: alcohols-buliding-blocks

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On August 30, 1956, Abe, Kyuji published a patent.Electric Literature of 62640-03-3 The title of the patent was Monoalkylaminoethanols. And the patent contained the following:

Hydroxyethylsaccharin (11.3 g.) is boiled with 25 cc. 20% NaOH solution 10 min., 16.5 g. Me2SO4 added, and warmed at 50-60掳 1 hr. to afford sirupy N-methyl-N-(hydroxyethyl)-慰-carboxybenzenesulfonamide (I). I is boiled with NaOH solution prepared from 4.4 g. NaOH, 13 cc. H2O, and 20 cc. alc. 1 hr., slightly acidified by dilute HCl, the alc. evaporated in vacuo, heated with 20 cc. 10% HCl 2 hrs., cooled, made alk. by NaOH, distilled with steam, the product caught in dilute HCl, evaporated, and dried to afford 72% monomethylaminoethanol hydrochloride, hygroscopic crystals; picrate, m. 146-7掳. Similarly were prepared monoethylaminoethanol hydrochloride, hygroscopic crystals (picrate, m. 125-6掳); and monomethylaminoethyl Ph ether hydrochloride, m. 174-5掳. These are useful as starting materials for antihistaminic drugs. The experimental process involved the reaction of 2-(Methylamino)ethan-1-ol hydrochloride(cas: 62640-03-3).Electric Literature of 62640-03-3

2-(Methylamino)ethan-1-ol hydrochloride(cas:62640-03-3) belongs to alcohols. In general, the hydroxyl group makes alcohols polar. Those groups can form hydrogen bonds to one another and to most other compounds. Owing to the presence of the polar OH alcohols are more water-soluble than simple hydrocarbons. Electric Literature of 62640-03-3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chremos, George N.; Zimmerman, Howard K. published an article in 1962, the title of the article was Protolysis equilibrium of N-substituted diethanolamines.Formula: C8H19NO2 And the article contains the following content:

Limiting pK values for the acidic dissociation of 6 N-substituted diethanolammonium ions in sq. solution are given, each at a series of temperatures in the range 15-55掳. The effect of the 3rd substituent on the N atom on the equilibrium appears to be chiefly an influence on the mutual interaction between the 2 hydroxyethyl groups present in each mol., although the ex- pected basicity-depressing effects are also found for the N-phenyl and N-benzyl compounds The experimental process involved the reaction of 2,2′-(tert-Butylazanediyl)diethanol(cas: 2160-93-2).Formula: C8H19NO2

2,2′-(tert-Butylazanediyl)diethanol(cas:2160-93-2) belongs to alcohols. In general, the hydroxyl group makes alcohols polar. Those groups can form hydrogen bonds to one another and to most other compounds. Owing to the presence of the polar OH alcohols are more water-soluble than simple hydrocarbons. Formula: C8H19NO2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Mazitova, F. N.; Ermakova, S. K.; Virobyants, R. A. published an article in 1962, the title of the article was The analysis of gaseous hydrocarbons by chromatographic adsorption on alumina.HPLC of Formula: 2160-93-2 And the article contains the following content:

cf. Korol, CA 54, 18176f; Kondrat’ev, et al., CA 54, 8468a. By use of 20-50 mesh Al2O3, to which 2% silicone oil (MS-2) has been added in a 6 mm. 脳 2 m. column at 30掳, the separation at a gas-carrier velocity of 50 cc./mm. of a mixture of 11 C1-4 gases is accomplished in 1 hr. A microflame detector with a registering instrument is illustrated. The experimental process involved the reaction of 2,2′-(tert-Butylazanediyl)diethanol(cas: 2160-93-2).HPLC of Formula: 2160-93-2

2,2′-(tert-Butylazanediyl)diethanol(cas:2160-93-2) belongs to alcohols. In general, the hydroxyl group makes alcohols polar. Those groups can form hydrogen bonds to one another and to most other compounds. Owing to the presence of the polar OH alcohols are more water-soluble than simple hydrocarbons. HPLC of Formula: 2160-93-2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts