Month: November 2022

Apparent properties of waterborne polyurethane emulsion was written by Ma, De-rong;Hu, Zheng-shui. And the article was included in Qingdao Keji Daxue Xuebao, Ziran Kexueban in 2013.Quality Control of 2-Butyl-2-ethylpropane-1,3-diol The following contents are mentioned in the article:

A high solid-containing waterborne polyurethane emulsion was prepared using IPDI, polyester polyol and dimethylolbutyric acid (DMBA) by self-emulsification method. Effects of emulsification temperature, small mol. diol and chain extender on emulsion viscosity, particle size and colloid morphol. were investigated. The results showed that the solid content of emulsion with low viscosity and good stability could reach 45% when DMBA mass fraction was 5.5% and emulsification temperature was 2°C. By adding 2-butyl-2-ethyl-1, 3-propanediol (BEPD) or chain extender isophorone diamine (IPDA), the particle size became smaller and the emulsion viscosity became lower by adjustment of intermol. interaction. Moreover, emulsion stability could be improved by using non-ionic hydrophilic chain extender trimethylolpropane polyethylene glycol monomethyl ether (TMPEG) which could shield the micelle electrostatic repulsion by means of synergy. This study involved multiple reactions and reactants, such as 2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4Quality Control of 2-Butyl-2-ethylpropane-1,3-diol).

2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Quality Control of 2-Butyl-2-ethylpropane-1,3-diol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Effect of high hydrostatic pressure on pasting properties, volatile flavor components, and water distribution of cooked black rice was written by Meng, Ling;Zhang, Wencheng;Hui, Ailing;Wu, Zeyu. And the article was included in Journal of Food Processing and Preservation in 2020.Category: alcohols-buliding-blocks The following contents are mentioned in the article:

The effect of high hydrostatic pressure (HHP) on pasting properties, volatile flavor components, and water distribution of cooked black rice (BR) was investigated. BR samples were subjected to HHP treatments at 200, 300, 400, and 500 MPa for 15 min, and then cooked for further evaluation. Results showed that HHP-treated samples exhibited lower viscosity compared to the control group, with the lowest value at 500 MPa. Among 126 flavor compounds identified in cooked BR stored for 7 days, the total contents of three key flavor components (alcs., ketones, and aldehydes) were greatly enhanced, indicating that HHP contributed to the aroma quality of cooked BR. Water characteristics were determined by low-field NMR (LF-NMR), and three water fractions were detected and identified as T21, T22, and T23. The value of T21 gradually decreased with the increase of pressure, suggesting that HHP reduced the retrogradation degree of cooked BR. This study involved multiple reactions and reactants, such as 3,7-Dimethyloctan-1-ol (cas: 106-21-8Category: alcohols-buliding-blocks).

3,7-Dimethyloctan-1-ol (cas: 106-21-8) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Category: alcohols-buliding-blocks

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Intramolecular n-type proton/hydrogen network in basic structures of vitamin B6 investigated by IRMPD spectroscopy was written by Fraschetti, Caterina;Guarcini, Laura;Speranza, Maurizio;Filippi, Antonello. And the article was included in International Journal of Mass Spectrometry in 2019.Computed Properties of C8H10ClNO3 The following contents are mentioned in the article:

A combined IRMPD and DFT study of the isomeric forms of protonated pyridoxine, pyridoxamine and pyridoxal has allowed to establish the spectroscopic and some peculiar structural features of these basic components of the vitamin B6 group in the gas phase, with the aim to offer a standpoint free from the environmental effects, which could help in understanding their behavior in the condensed phase typical of biol. systems. The imine-enamine and the neutral-zwitterion tautomerism have been considered. Analyzing the exptl. and theor. data a detailed characterization of the protonation sites and intramol. proton/hydrogen bonding interactions emerged. The comparison between exptl. and theor. signals of free N-H and O-H bonds and when they are involved as proton/hydrogen bond donors towards n-acceptors suggests a correspondence between their anharmonicity and the intensity of the IRMPD signals, up to the so called IRMPD transparency. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Computed Properties of C8H10ClNO3).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Computed Properties of C8H10ClNO3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Enzymatic modification of oat globulin enables covalent interaction with procyanidin B2 was written by Korpela, Bei;Pitkanen, Leena;Heinonen, Marina. And the article was included in Food Chemistry in 2022.COA of Formula: C30H26O12 The following contents are mentioned in the article:

The effect of enzyme treatment on protein-tannin interactions was investigated using up-to-date anal. approaches for improving their phys. properties. The formation of ligands between procyanidin B2 and native oat globulin (OG) was observed to be affected by the ratio of procyanidin B2 to OG and the availability of tryptophan. For the transglutaminase-treated OG, the results obtained from CD (CD) and size exclusion chromatog. (SEC) revealed that procyanidin B2 acted as an acyl acceptor in the process of OG deamidation. Procyanidin B2 also inhibited the non-covalent protein-protein interactions occurring between the aromatic side-chains or sedimentation of tryptophan aggregates. For trypsin-treated OG, procyanidin B2 interacted with phenylalanine and the tryptophan side-chain of OG. The inhibition of procyanidin B2 towards protein-protein aggregation was proved by the observation of CD, SEC and asym. flow field-flow fractionation. This study involved multiple reactions and reactants, such as (2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol (cas: 29106-49-8COA of Formula: C30H26O12).

(2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol (cas: 29106-49-8) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.COA of Formula: C30H26O12

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Immobilization of microbial consortium for glutaric acid production from lysine was written by Gao, Cong;Wang, Jiaping;Guo, Liang;Hu, Guipeng;Liu, Jia;Song, Wei;Liu, Liming;Chen, Xiulai. And the article was included in ChemCatChem in 2021.Synthetic Route of C9H18O5S The following contents are mentioned in the article:

Glutaric acid is an important C5 platform compound for the synthesis of nylon polymers. However, its production titer and cost are limited by the need for expensive cofactors addition as well as the difficulty of reusing microbial catalysts. Herein, to address these problems, two regeneration systems each for NAD(P)+ and α-ketoglutaric acid were introduced into a five-enzyme cadaverine pathway for a whole-cell biocatalytic approach. We demonstrated the efficient conversion of lysine to glutaric acid in a synthetic microbial consortium manner, producing 73.2 g/L glutaric acid with a 74% molar yield in a 5-L bioreactor scale. Moreover, with a colloidal chitin-based immobilization, the engineered microbial consortium exhibited good stability and reusability in a five-cycle bioconversion. This study provides an efficient microbial platform for glutaric acid production by developing a cheaper and universal cell immobilization approach. This study involved multiple reactions and reactants, such as (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1Synthetic Route of C9H18O5S).

(2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Synthetic Route of C9H18O5S

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Coupled Membrane Lipid Miscibility and Phosphotyrosine-Driven Protein Condensation Phase Transitions was written by Chung, Jean K.;Huang, William Y. C.;Carbone, Catherine B.;Nocka, Laura M.;Parikh, Atul N.;Vale, Ronald D.;Groves, Jay T.. And the article was included in Biophysical Journal in 2021.Synthetic Route of C37H74NO8P The following contents are mentioned in the article:

Lipid miscibility phase separation has long been considered to be a central element of cell membrane organization. More recently, protein condensation phase transitions, into three-dimensional droplets or in two-dimensional lattices on membrane surfaces, have emerged as another important organizational principle within cells. Here, we reconstitute the linker for activation of T cells (LAT):growth-factor-receptor-bound protein 2 (Grb2):son of sevenless (SOS) protein condensation on the surface of giant unilamellar vesicles capable of undergoing lipid phase separations Our results indicate that the assembly of the protein condensate on the membrane surface can drive lipid phase separation This phase transition occurs isothermally and is governed by tyrosine phosphorylation on LAT. Furthermore, we observe that the induced lipid phase separation drives localization of the SOS substrate, K-Ras, into the LAT:Grb2:SOS protein condensate. This study involved multiple reactions and reactants, such as (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5Synthetic Route of C37H74NO8P).

(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Synthetic Route of C37H74NO8P

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Evaluating the changes in phytochemical composition, hypoglycemic effect, and influence on mice intestinal microbiota of fermented apple juice was written by Wang, Xiaowei;Wang, Yaqin;Han, Mengzhen;Liang, Jingjing;Zhang, Meina;Bai, Xue;Yue, Tianli;Gao, Zhenpeng. And the article was included in Food Research International in 2022.Computed Properties of C30H26O12 The following contents are mentioned in the article:

Apples are rich in phenolic antioxidants, which have various beneficial effects on human health. The purposes of our study were to evaluate the effects of Lactobacillus fermentum 21828 fermentation on the phytochem. composition and bioactivity of Aksu (Fuji) apple juice (AJ), and to evaluate the hypoglycemic effect of fermented AJ (FAJ) and its effect on intestinal flora. Fermentation altered the phytochem. and enhanced the biol. activity (hypoglycemic and antioxidant activities) of AJ. FAJ improved fasting blood glucose and insulin levels in diabetic mice, regulated blood lipid metabolism, reduced oxidative damage, restored damaged islet cells, and reshaped the intestinal flora of diabetic mice by increasing the relative abundance of Actinobacteria, Bifidobacteria, and Faecalibaculum. The results indicate that FAJ is a fermented product that is rich in bioactive components and has potential hypoglycemic and antioxidant activities. This study involved multiple reactions and reactants, such as (2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol (cas: 29106-49-8Computed Properties of C30H26O12).

(2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol (cas: 29106-49-8) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Computed Properties of C30H26O12

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yb(III), Sm(III) and La(III) complexes of a tetradentate pyridoxal Schiff base ligand: Their DNA-binding activity and bio-imaging applications was written by Chakraborty, Moumita;Mondal, Satyajit;Cardin, Christine;Rheingold, Arnold L.;Das Mukhopadhyay, Chitrangada;Kumar Chattopadhyay, Shyamal. And the article was included in Polyhedron in 2020.HPLC of Formula: 65-22-5 The following contents are mentioned in the article:

Yb(III), Sm(III) and La(III) complexes of a tetradentate Schiff base ligand, bis(pyridoxylidene)ethyelenediamine, are reported. Single crystal x-ray structures of the complexes reveal that in all the three complexes the Ln(III) ions are in a distorted dodecahedral geometry with N₄O₄-coordination environment provided by two coordinated ligands. Fluorescence spectroscopy shows that in the Yb(III) and Sm(III) complexes energy transfer from ligand centered excited state leads to population of an emissive f-f excited state. The complexes bind to ct-DNA, with high binding constant (K_b) comparable to those compounds (like ethydium bromide) which bind by intercalative mode. Cytotoxicity study shows that the complexes have quite low cytotoxicity towards HeLa cells. Further, they exhibited fast response, bright fluorescence and stability at physiol. pH, making them suitable for use in fluorescence bio-imaging. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5HPLC of Formula: 65-22-5).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.HPLC of Formula: 65-22-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Effects of high pressure in combination with the type of aging on the eating quality and biochemical changes in pork loin was written by Hwang, Su-In;Hong, Geun-Pyo. And the article was included in Meat Science in 2020.COA of Formula: C10H22O The following contents are mentioned in the article:

This study investigated the effects of high pressure (0.1, 150 and 400 MPa) and the aging method (wet- and dry-aging) on the quality characteristics of pork loin. Pork pressurized at the target pressure levels was aged at 1°C for 3 wk in vacuum packaging (wet-aging) or a moisture/vapor permeable bag (dry-aging). The water binding properties, shear force, color, volatile compounds and microbial counts were estimated as the quality characteristics of aged pork. Despite dry-aged pork having distinctive flavor characteristics, high moisture loss during aging was estimated as the most important factor that affected the quality of aged pork. Alternately, wet aging showed advantages of producing tender and juicy pork, and moderate pressurization (150 MPa) modified or improved the qualities of wet-aged pork. Consequently, this study indicated that pressurization followed by wet-aging had potential application as a meat tenderizing technique. This study involved multiple reactions and reactants, such as 3,7-Dimethyloctan-1-ol (cas: 106-21-8COA of Formula: C10H22O).

3,7-Dimethyloctan-1-ol (cas: 106-21-8) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.COA of Formula: C10H22O

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

SIRT1 provides new pharmacological targets for polydatin through its role as a metabolic sensor was written by Sun, Zhicheng;Wang, Xiyang;Xu, Zhenchao. And the article was included in Biomedicine & Pharmacotherapy in 2021.Synthetic Route of C20H22O8 The following contents are mentioned in the article:

A review. The SIRT family of proteins constitutes highly conserved deacetylases with diverse and extensive functions. These proteins have specific biol. functions, including regulation of transcription, cell cycle, cell differentiation, apoptosis, stress, metabolism, and genomic stability. Polydatin is a monocrystalline compound isolated from a Chinese herb, Polygonum cuspidatum. The pharmacol. mechanisms of polydatin are mostly unclear but involve members of the SIRT protein family, among which SIRT1 plays a vital role. Polydatin is usually considered a potential SIRT1 activator. This review summarizes the signaling mechanism of polydatin involving SIRT1 and discusses the roles of related signal mols. such as PGC-1α, Nrf2, p38-MAPK, NLPR3 inflammasome, and p53. Further, we describe the metabolic regulation of related biol. macromols. and demonstrate that SIRT1, as a metabolic sensor, may act as a new pharmacol. target for polydatin. This study involved multiple reactions and reactants, such as (2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (cas: 27208-80-6Synthetic Route of C20H22O8).

(2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (cas: 27208-80-6) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Synthetic Route of C20H22O8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts