Month: November 2022

In 2019,Applied Surface Science included an article by Qu, Ke; Kondengaden, Shukkoor M.; Li, Jian; Wang, Xuewei; Sevilla, Michael D.; Li, Lei; Zeng, Xiangqun. Application of 627-18-9. The article was titled 《Carbohydrate-functionalized polythiophene biointerface: design, fabrication, characterization and application for protein analysisã€? The information in the text is summarized as follows:

In this study, a general method for fabricating glycosylated conductive polymer (CP) biointerface was demonstrated for a label-free electrochem. biosensor. A 3-(3-azidopropoxy) thiophene monomer was designed and synthesized. By electrochem. polymerizing this monomer in ionic liquid [Bmim][BF4], a unique conductive polymer was formed, allowing grafting of lactose or ferrocene via post-polymerization Cu(I)-catalyzed click reaction. X-ray photoelectron spectra validated the covalent 1, 2, 3-triazole ring formation during this click functionalization. SEM study showed an increasing of the crystallinity of the CPs after click functionalization with lactose or ferrocene. The binding of the fabricated lactosylated polythiophene biointerface with Erythrina Cristagalli lectin (ECL) was characterized with differential pulse voltammetry, showing excellent sensitivity and selectivity for ECL anal. This study illustrated a new glycosylated CP biointerface design and fabrication method that can be applied for developing real-time and label-free electrochem. biosensor to study protein-carbohydrate interactions for protein anal. In the part of experimental materials, we found many familiar compounds, such as 3-Bromopropan-1-ol(cas: 627-18-9Application of 627-18-9)

3-Bromopropan-1-ol(cas: 627-18-9) was used in the synthesis of fluorescent halide-sensitive quinolinium dyes and molten salt-polymers. Furthermore, it was used in the synthesis of chiral, quaternary prolines via cyclization of quaternary amino acids.Application of 627-18-9

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2019,Green Chemistry included an article by Sun, Kang-kang; Sun, Jia-lin; Lu, Guo-Ping; Cai, Chun. Reference of 3-Pyridinemethanol. The article was titled 《Enhanced catalytic activity of cobalt nanoparticles encapsulated with an N-doped porous carbon shell derived from hollow ZIF-8 for efficient synthesis of nitriles from primary alcohols in waterã€? The information in the text is summarized as follows:

A cobalt catalyst derived from a unique core-shell structure based on hollow ZIF-8 and ZIF-67 (ZIF-67@ZIF-8) is prepared, which exhibits excellent catalytic efficiency for the synthesis of nitriles from alcs. in water under mild conditions (1 atm O2, 50°C) owing to its large BET surface area, high pore volume, high basicity and hydrophilicity.3-Pyridinemethanol(cas: 100-55-0Reference of 3-Pyridinemethanol) was used in this study.

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. Reference of 3-Pyridinemethanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2019,Molecules included an article by Montgomery, Deanna; Anand, Jessica P.; Baber, Mason A.; Twarozynski, Jack J.; Hartman, Joshua G.; Delong, Lennon J.; Traynor, John R.; Mosberg, Henry I.. COA of Formula: C6H7BO3. The article was titled 《Structure-activity relationships of 7-substituted dimethyltyrosine-tetrahydroisoquinoline opioid peptidomimeticsã€? The information in the text is summarized as follows:

The opioid receptors modulate a variety of biol. functions, including pain, mood, and reward. As a result, opioid ligands are being explored as potential therapeutics for a variety of indications. Multifunctional opioid ligands, which act simultaneously at more than one type of opioid receptor, show promise for use in the treatment of addiction, pain, and other conditions. Previously, we reported the creation of bifunctional kappa opioid receptor (KOR) agonist/mu opioid receptor (MOR) partial agonist ligands from the classically delta opioid receptor (DOR) antagonist selective dimethyltyrosine-tetrahydroisoquinoline (Dmt-Tiq) scaffold through the addition of a 7-benzyl pendant on the tetrahydroisoquinoline ring. This study further explores the structure-activity relationships surrounding 7-position pendants on the Dmt-Tiq scaffold. Some analogs maintain a KOR agonist/MOR partial agonist profile, which is being explored in the development of a treatment for cocaine addiction. Others display a MOR agonist/DOR antagonist profile, which has potential to be used in the creation of a less addictive pain medication. Ultimately, we report the synthesis and in vitro evaluation of novel opioid ligands with a variety of multifunctional profiles. The experimental process involved the reaction of 2-Hydroxyphenylboronic acid(cas: 89466-08-0COA of Formula: C6H7BO3)

2-Hydroxyphenylboronic acid(cas: 89466-08-0) belongs to acyl phenylboronic acid. Phenylboronic acid (PBA) has been used to extract β-blockers (a class of aminoalcohol-containing drugs) from aqueous solution, rat, and human plasma. COA of Formula: C6H7BO3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

The author of 《An efficient multicomponent synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles catalyzed by a magnetic nanoparticle supported Lewis acidic deep eutectic solventã€?were Nguyen, Thanh Thi; Thi Le, Ngoc-Phuong; Nguyen, The Thai; Tran, Phuong Hoang. And the article was published in RSC Advances in 2019. Computed Properties of C7H6O2 The author mentioned the following in the article:

A mild and highly efficient reaction for the synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles I (R = 2-hydroxyphenyl, 2-fluorophenyl, 1H-indol-3-yl, etc.; R1 = H, phenyl) catalyzed by a magnetically supported Lewis acidic deep eutectic solvent on magnetic nanoparticles (LADES@MNP) has been developed via one-pot multicomponent processes under solvent-free sonication. These reactions have good to excellent yields, mild conditions, and work-up simplicity. This method represents a new method for the preparation of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles I. More importantly, LADES@MNP can be easily recovered by magnetic separation and reused five times without significant loss of catalytic activity. In the experiment, the researchers used 3-Hydroxybenzaldehyde(cas: 100-83-4Computed Properties of C7H6O2)

3-Hydroxybenzaldehyde(cas: 100-83-4) can be used as a reactant along with ethyl acetoacetate and thiourea in the synthesis of corresponding dihydropyrimidine-2-thione (monastrol), using Yb(OTf)3 as a catalyst by Biginelli cyclocondensation reaction.Computed Properties of C7H6O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

The author of 《Ni-Catalyzed reductive arylalkylation of unactivated alkenesã€?were Jin, Youxiang; Wang, Chuan. And the article was published in Chemical Science in 2019. Synthetic Route of C3H7BrO The author mentioned the following in the article:

In this protocol Ni-catalyzed reductive arylalkylation of unactivated alkenes tethered to aryl bromides with primary alkyl bromides was accomplished, which provided a new path to construct diverse benzene-fused carbo- and heterocyclic cores including indanes, tetrahydroisoquinolines, indolines and isochromanes I [R1 = Me, Et, i-Pr, cyclohexyl; R2 = H, Me, Et; R3 = 5-OMe, 5-F, 4-Cl, etc.; R4 = CN, OAc, F, etc.; X = CH2, NH, NMe, O; m = 0,3,4,5,6; n = 0,1]. Notably, this new method circumvented the pregeneration of organometallics and demonstrated high tolerance to a wide range of functional groups. The preliminary mechanistic investigations suggested a reaction pathway with an intermediate reduction In addition to this study using 3-Bromopropan-1-ol, there are many other studies that have used 3-Bromopropan-1-ol(cas: 627-18-9Synthetic Route of C3H7BrO) was used in this study.

3-Bromopropan-1-ol(cas: 627-18-9) was used in the synthesis of fluorescent halide-sensitive quinolinium dyes and molten salt-polymers. Furthermore, it was used in the synthesis of chiral, quaternary prolines via cyclization of quaternary amino acids.Synthetic Route of C3H7BrO

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

The author of 《All-organic covalent organic framework/polyaniline composites as stable electrode for high-performance supercapacitorsã€?were Liu, Shuai; Yao, Lu; Lu, Yi; Hua, Xiaolin; Liu, Jiaqiang; Yang, Zhi; Wei, Hao; Mai, Yiyong. And the article was published in Materials Letters in 2019. SDS of cas: 34374-88-4 The author mentioned the following in the article:

A novel all-organic composite of covalent organic framework (COF) and polyaniline (PANI) was designed and prepared By combining the highly porous and redox active TpPa-COF and conductive PANI, TpPa-COF@PANI composite electrodes showed greatly improved performance in supercapacitor application. After 30,000 cycles, the capacity retention rate of the battery is as high as 83%, which indicates that the electrode has great cycling stability. The strategy reported in this work may shed light on the design of new redox active COFs based Faradaic supercapacitors and have a great potential for other electrochem. devices.2,4,6-Trihydroxybenzene-1,3,5-tricarbaldehyde(cas: 34374-88-4SDS of cas: 34374-88-4) was used in this study.

2,4,6-Trihydroxybenzene-1,3,5-tricarbaldehyde(cas: 34374-88-4) is a member of phloroglucinol derivatives. Regarding monomeric phloroglucinols, this group encompasses acryl phloroglucinols, phloroglucinol-terpene adducts, phloroglucinol glycosides, halogenated phloroglucinols, prenylated phloroglucinols, and cyclicroup polyketides.SDS of cas: 34374-88-4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

The author of 《A photo-selective chain-end modification of polyacrylate-iodide and its application in patterned polymer brush synthesisã€?were Chen, Chen; Wang, Chen-Gang; Guan, Wenxun; Goto, Atsushi. And the article was published in Polymer Chemistry in 2019. Name: 4-Aminobutan-1-ol The author mentioned the following in the article:

A photo-selective chain-end modification of polyacrylate-iodide (polymer-I) was developed. In the presence of a functional primary amine (NH2-R-X with an X functionality) and formic acid, by simply switching the UV light on and off, polymer-I was selectively converted to hydrogen-terminated polymer-H and chain-end functionalized polymer-NH-R-X (polymer-X), resp. The scopes of the amenable functional X groups and polyacrylates are wide, and hence this method may serve as a general and versatile method for selective chain-end modification. As a useful application, this method was successfully used to fabricate chain-end patterned binary polymer brushes on surfaces. This method is free from metal, amenable to various functionalities, and useful for designing a range of chain-end functionalized polymers and surface-functionalized materials. The results came from multiple reactions, including the reaction of 4-Aminobutan-1-ol(cas: 13325-10-5Name: 4-Aminobutan-1-ol)

4-Aminobutan-1-ol(cas: 13325-10-5) is used in the synthesis of NSAIDs with anti-inflammatory properties. Also used in the synthesis of polyamine transport ligands with specificity against human cancers allowing easy access to specific cancer cells.Name: 4-Aminobutan-1-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《Microwave-heated γ-Alumina Applied to the Reduction of Aldehydes to Alcoholsã€?was published in ChemCatChem in 2020. These research results belong to Dhokale, Bhausaheb; Susarrey-Arce, Arturo; Pekkari, Anna; Runemark, August; Moth-Poulsen, Kasper; Langhammer, Christoph; Haerelind, Hanna; Busch, Michael; Vandichel, Matthias; Sunden, Henrik. Recommanded Product: 3-Pyridinemethanol The article mentions the following:

The development of cheap and robust heterogeneous catalysts for the Meerwein-Ponndorf-Verley (MPV) reduction is desirable due to the difficulties in product isolation and catalyst recovery associated with the traditional use of homogeneous catalysts for MPV. Microwave heated γ-Al2O3 which can be used for the reduction of aldehydes RCHO (R = CH2C6H5, 2-furyl, 4-pyridyl, etc.) to alcs. RCH2OH has been described. The reaction is efficient and has a broad substrates scope. The products can be isolated by simple filtration, and the catalyst can be regenerated. With the use of microwave heating, the heating can be directed to the catalyst rather than to the whole reaction medium. Furthermore, DFT was used to study the reaction mechanism, and it was conclude that a dual-site mechanism is operative where the aldehyde and 2-propoxide are situated on two adjacent Al sites during the reduction Addnl., volcano plots were used to rationalize the reactivity of Al2O3 in comparison to other metal oxides. In addition to this study using 3-Pyridinemethanol, there are many other studies that have used 3-Pyridinemethanol(cas: 100-55-0Recommanded Product: 3-Pyridinemethanol) was used in this study.

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Recommanded Product: 3-Pyridinemethanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《Ambipolar organic field-effect transistors based on N-Unsubstituted thienoisoindigo derivativesã€?was published in Dyes and Pigments in 2020. These research results belong to Yoo, Dongho; Hasegawa, Tsukasa; Kohara, Akihiro; Sugiyama, Haruki; Ashizawa, Minoru; Kawamoto, Tadashi; Masunaga, Hiroyasu; Hikima, Takaaki; Ohta, Noboru; Uekusa, Hidehiro; Matsumoto, Hidetoshi; Mori, Takehiko. Name: Oxetan-3-ol The article mentions the following:

To investigate a hybrid of isoindigo and thienoisoindigo (TIIG), a new series of unsym. TIIG analogs, in which one of the outer thiophene rings of TIIG is replaced by benzene (CS) or pyridine (NS) are prepared In addition, the π-skeleton extension effects are studied by examining α-substituted TIIG derivatives with thienyl (Dth-TIIG), furyl (Dfu-TIIG), and 1-phenyl-5-pyrazolyl groups (Bis(1-ph-5-py)-TIIG). These materials exhibit ambipolar transistor properties as expected from the energy levels. Dth-TIIG and Dfu-TIIG show hole mobilities exceeding 0.05 cm2 V-1 s-1, and electron mobilities about 0.04 cm2 V-1 s-1, which are close to those of the di-Ph derivative These mols. are arranged nearly perpendicularly to the substrates in the thin films, and Dth-TIIG has a brickwork-like structure, whereas Dfu-TIIG has uniform columns. CS and Bis(1-ph-5-py)-TIIG have uniform stacking structures, but NS has a dimerized stacking structure due to the slightly bent mol. plane that results from largely unbalanced electron d. In the experimental materials used by the author, we found Oxetan-3-ol(cas: 7748-36-9Name: Oxetan-3-ol)

Oxetan-3-ol(cas: 7748-36-9) is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.Name: Oxetan-3-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《One-Pot Synthesis of 4-Quinolone via Iron-Catalyzed Oxidative Coupling of Alcohol and Methyl Areneã€?was published in Organic Letters in 2020. These research results belong to Lee, Seok Beom; Jang, Yoonkyung; Ahn, Jiwon; Chun, Simin; Oh, Dong-Chan; Hong, Suckchang. Recommanded Product: 3-Pyridinemethanol The article mentions the following:

Herein, we describe the iron(III)-catalyzed oxidative coupling of alc./methyl arene with 2-amino Ph ketone to synthesize 4-quinolone. Alcs. and Me arenes are oxidized to the aldehyde in the presence of an iron catalyst and di-tert-Bu peroxide, followed by a tandem process, condensation with amine/Mannich-type cyclization/oxidation, to complete the 4-quinolone ring. This method tolerates various kinds of functional groups and provides a direct approach to the synthesis of 4-quinolones from less functionalized substrates. In the experimental materials used by the author, we found 3-Pyridinemethanol(cas: 100-55-0Recommanded Product: 3-Pyridinemethanol)

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Recommanded Product: 3-Pyridinemethanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts