Month: November 2022

Some anticonvulsant agents derived from 1,3-propanediols was written by Ludwig, B. J.;Piech, E. C.. And the article was included in Journal of the American Chemical Society in 1951.Quality Control of 2-Butyl-2-ethylpropane-1,3-diol The following contents are mentioned in the article:

Mono- and dicarbamate esters of 2,2-disubstituted-1,3-propanediols were prepared for evaluation as anticonvulsants. Preparation of 2,2-disubstituted-1,3-propanediol dicarbamates. General method: COCl₂ (20 g.) in 200 cc. PhMe at -10° treated with a cooled solution of 13.2 g. (HOCH₂)₂CEt₂ and 38 g. antipyrine in 100 cc. CHCl₃ (temperature kept at -5 to 0°), the mixture let stand overnight at room temperature, filtered, the filtrate treated with NH₃ (moderate cooling), the amide filtered off, extracted with 250 cc. cold water, and recrystallized from water yielded 17.5 g. di-Et compound (I). The PhMe-CHCl₃ filtrate concentrated and the residue distilled in vacuo yielded 75% 2,2-diethyl-1,3-propanediol bis(chlorocarbonate), b_4.5 108°, n_D²⁵ 1.4628. For the compounds RR’C(CH₂OCONH₂)₂, R, R’, yield (%), and m.p. (all m.ps. uncorrected) are: Me, Me, 82, 151.5-2.5°; Et, Me, 65, 135-6°; Me, Pr, 90, 105-6°; Me, iso-Pr, 61, 99-100°; Et, Et, 80, 149-50°; Et, Bu, 63, 117-18°; Et, Ph, 70, 119-20°; Pr, Pr, 87, 152-3°; RR’ = (CH₂)₅, 60, 112-13°. N-Substituted-2,2-diethyl-1,3-propanediol dicarbamates were prepared by the same procedure (R, yield (%), and m.p. given): Me, 56, 85-6°; Ph, 67, 135.5-6.5°; Ac, 65, 123-4°; PhCH₂CO₂, 20, 204-5°; Et, 50,-[bis(diethylamino) derivative b₅ 130-2°, n_D²⁵ 1.4569]. The following method yielded cyclic carbonate derivatives: a cooled 10% solution of 0.1 mole of COCl₂ in PhMe added to 13.2 g. I and 0.2 mole antipyrine in a min. of CHCl₃ (temperature held at 25°), the mixture held at 25° overnight, filtered, the filtrate concentrated, the residue dissolved in Et₂O, the Et₂O solution extracted with water, and the Et₂O evaporated yielded 10.5 g. 5,5-diethyl-2-m-dioxanone, b₂ 131-2°, m. 45-6° (from C₆H₆-petr. ether). For other 5,5-disubstituted-2-m-dioxanones, R, R’, yield (%), and m.p. are: Me, Me, 60, 110-11°; Me, Pr, 74, b_0.25 95-104°, n_D²⁵ 1.4550; Et, Et, 66, 45-6°; Et, Bu, 80, b₁ 125-30°, n_D²⁵ 1.4638; Et, Ph, 85, 99.5-100.5°. A 5,5-disubstituted-2-m-dioxanone (5 g.) in a stainless-steel pressure bomb cooled in Dry Ice, 7.5 cc. NH₃ added, the vessel closed and shaken 48 hrs. at room temperature, and the NH₃ evaporated yielded 2,2-disubstituted-3-hydroxypropyl carbamates, HOCH₂CRR’CH₂OCONH₂ (R, R’, yield (%), and m.p. given): Me, Me, 53, 60-1°; Me, Pr, 60, 61.5-2.5°; Et, Et, 75, 75-6°; (N-Me derivative, n_D²⁵ 1.4640, b_0.5 110-16°; N,N-di-Et derivative, n_D²⁵ 1.4587, b_0.5 104-8°); Et, Bu, 73, 66.5-7.5°; Et, Ph, 69, 89-90°. This study involved multiple reactions and reactants, such as 2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4Quality Control of 2-Butyl-2-ethylpropane-1,3-diol).

2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Quality Control of 2-Butyl-2-ethylpropane-1,3-diol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synthesis of some cyclopropane and spiran hydrocarbons was written by Shortridge, R. W.;Craig, R. A.;Greenlee, K. W.;Derfer, J. M.;Boord, C. E.. And the article was included in Journal of the American Chemical Society in 1948.Application In Synthesis of 2-Butyl-2-ethylpropane-1,3-diol The following contents are mentioned in the article:

Details are given of the preparation from Me₂CHCHO and HCHO of 76% Me₂C(CH₂OH)₂ which with PBr₃ yields 46% Me₂C(CH₂Br)₂, b₉ 68°, n²_D 1.5050, d²⁰₄ 1.6934 (all n and d. are at 20°). A mixture 1900 ml. 95% EtOH, 90 ml. H₂O, and 628 g. Zn dust, brought to gentle reflux and treated dropwise with 562 g. Me₂C(CH₂Br)₂, with heating and stirring 24 hrs., gives 162 g. 1,1-dimethylcyclopropane, b₇₆₀ 19.9°, f.p. -108.4 to -107.3°. MeEtCHCH₂CHO gives 91% 2,2-diethyl-1,3-propanediol, b₁₃ 131°, m. 61-1.6°; PBr₃ yields 40% 1,3-dibromo-2,2-diethylpropane, b₁₀ 97°, m. 39.2-40.6°; this gives 92% 1,1-diethylcyclopropane (I), b₇₆₀ 88.67°, f.p. -105.91°, n 0.7318, d. 1.4042. EtPrCHCH₂CHO yields 70% 2-ethyl-2-butyl-1,3-propanediol, b₁₀ 152°, m. 41.4-1.9°; PBr₃ gives about 47% 1,3-dibromo-2-ethyl-2-butylpropane, b₁₆ 133°, d. 1.4400, n 1.5018; this yields 94% 1-ethyl-1-butylcyclopropane, b₇₆₀ 140.41°, f.p. -102.68°, d. 0.7559, n 1.4183. Five mols. each of (CH:CH₂)₂ and CH₂:CHCHO and 5 g. hydroquinone, heated to 130° (temperature rise to 185°), give 74% 3-cyclohexene-1-carboxaldehyde, b₇₆₀ 164°, f.p. -96.1°, d. 0.9709, n 1.4725; this yields 84% 4,4-bis(hydroxymethyl)cyclohexene, b₃ 128°, m. 92°, giving on catalytic reduction in MeOH over Raney Ni at 45° and 1000 lb./sq. in. 1,1-bis(hydroxymethyl)cyclohexane, which yields 27% 1,1-bis(bromomethyl)cyclohexane, b₆ 117°, d. 1.6302, n 1.5390; cyclization yields 91% spiro[2.5]octane (II), b₇₆₀ 125.5°, f.p. -86.2°, d. 0.8282, n 1.4476. (CH:CH₂)₂ and MeCH:CHCHO give 46% 6-methyl-3-cyclohexene-1-carboxaldehyde, b₆₄ 99°, b₇₆₀ 117.8°, d. 0.9500, n 1.4680; this yields 4,4-bis(hydroxymethyl)-5-methylcyclohexene, b₆ 134°, m. 45°. 1,1-Bis(hydroxymethyl)-2-methylcyclohexane (m. 77°, 51%) yields 28% 1,1-bis(bromomethyl)-2-methylcyclohexane, b₄ 115°, n 1.5380; cyclization yields 89% 4-methylspiro[2.5]octane (III), b₇₆₀ 149°, f.p. -53.6°, d. 0.8386, n 1.4529. I, hydrogenated over Raney Ni at 180° and 2000 lb./sq. in., gives 80% Me₂CEt₂; at 155° and 1900 lb./sq. in., II over Raney Ni gives 91% 1,1-dimethylcyclohexane; III gives 1,1,2-trimethylcyclohexane, b₇₆₀ 145.2°, f.p. -29.2°, d. 0.7986, n 1.4385. When a gem-dialkylcyclopropane or a spirane containing a cyclopropane ring is hydrogenated under the above conditions, rupture of the cyclopropane ring occurs almost exclusively at the bond opposite the gem-disubstituted C atom. Thus, hydrogenation under controlled conditions can provide an easy, reliable method for proving the structure of these types of compounds and in some cases it may prove to be a good preparative reaction for synthesizing gem-dimethylcycloalkanes with rings containing more than 3 C atoms. This study involved multiple reactions and reactants, such as 2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4Application In Synthesis of 2-Butyl-2-ethylpropane-1,3-diol).

2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Application In Synthesis of 2-Butyl-2-ethylpropane-1,3-diol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

The preparation of N-substituted 1,3-propanediol dicarbamates was written by Schneider, G.;Halmos, M.;Meszaros, P.;Kovaes, O.. And the article was included in Monatshefte fuer Chemie in 1963.SDS of cas: 115-84-4 The following contents are mentioned in the article:

As part of a study of 1,3-diols, a number of substituted 1,3-propanediol dicarbamates was prepared The 2,2-dialkyl-1,3-propanediol dicarbamates rand the sym. N,N’-di- (I) or N,N,N’,N’-tetrasubstituted (II) derivatives were obtained by treating the corresponding dichlorides with aqueous NH₃ or dry alkylamine. A typical preparation of I involved treatment of a solution of 1 mole of diol in 500 cc. absolute C₆H₆ with COCl₂ at 0-5°, followed by reaction with concentrated NH₃. After separation of the aqueous phase, the C₆H₆ solution was washed with H₂O, dried (Na₂SO₄), and concentrated to yield a solid product. By this method were prepared the following I, RR¹C(CH₂O₂CNH₂)₂ (R,R¹,and m.p. given): Me, Me, 152°; Et, Et, 158°; Me, Pr, 99-100°; Et, Bu, 118°. The preparation of II was carried out in a manner analogous to that of I, except that the reaction with COCl₂ was carried out in the presence of R₂NH. The mixture was kept 1 day at room temperature, the amine hydrochloride was removed, and gaseous alkylamine passed into the dichloride solution at 5°. After removal of the amine hydrochloride, II was isolated as described above. In this manner were prepared the following II, RR¹C(CH₂O₂CNR²R³)₂ (R, R¹, R², R³, and m.p. or n²⁵_D given): Me, Me, Me, H, 39-40°; Et, Et, Me, H, 85-6°; Me, Pr, Me, H, 1.4872; Et, Bu, Me, H, 1.4686; Me, Me, Me, Me, 14562; Et, Et, Me, Me, 30-2°; Me, Pr, Me, Me, 1.4596; Et, Bu, Me, Me, 1.4661; Me, Me, iso-Pr, H, 92-3°; Et, Et, iso-Pr, H, 44-5°, Me, Pr, iso-Pr, H, 68-9°; Et, Bu, iso-Pr, H, 1.4627. N-Monoalkyl and mixed N,N’-dialkyl-1,3-propanediol dicarbamates (III) were obtained from the appropriate monocarbamates (IV). The latter were frequently prepared by reaction of 1.5 moles of the corresponding cyclic carbonate with 2 moles of liquid alkylamine for 6 hrs. at 80° in an autoclave. The cooled reaction mixture was dissolved in C₆H₆, the C₆H₆ and excess amine removed, and IV isolated. By this method were prepared the following IV, RR¹C(CH₂OH)CH₂O₂CNR²R³ (R, R¹, R², R³, and m.p. or n²⁵_D given): Me, Me, iso-Pr, H, 58-60°, Et, Et, iso-Pr, H, 53°; Me, Pr, iso-Pr, H, 1.4594; Et, Bu, iso-Pr, H, 1.4540; Me, Pr, Bu, H, 1.4547. V, n²⁵5_D 1.4480, was prepared in 95% yield by reaction of the corresponding diol with diethyl carbonate and Na at 90°; use of a large amount of Na avoided formation of polymers. The N-monoalkyl-2,2-dialkyl-1-3-propanediol dicarbamates were prepared by treatment of a C₆H₆ solution of 1 mole IV with 1 mole COCl₂, followed by reaction with aqueous NH₃. The mixed N,N-dialkyl derivatives of III were prepared similarly, except that the reaction with COCl₂ was carried out in the presence of 1 mole R₂NH. The remainder of this procedure was similar to that described for the preparation of II. By this method were prepared the following RR¹C(CH₂O₂CNR²Ra³CH₂O₂CNR⁴Rp5 (R, R1, R², R³, R⁴, R⁵,and m.p. or n²⁵_D given): Me, Me, iso-Pr, H, H, H, 118-20°; Et, Et, iso-Pr, H, H, H, 88-90°; Me, Pr, iso-Pr, H, H, H, 91-3°; Et, Bu, iso-Pr, H, H, H, 74-6°; Me, Me, iso-Pr, H, Me, H, 75°; Et, Et, iso-Pr, H, Me, H, 63-5°; Me, Pr, iso-Pr, H, Me, H, 76-8°; Et, Bu, iso-Pr, H, Me, H, 34-5°; Me, Me, iso-Pr, H, Me, Me, 43°; Et, Et, iso-Pr, H, Me, Me, 48-50°; Me, Pr, iso-Pr, H, Me, Me, 1.4560; Et, Bu, iso-Pr, H, Me, Me, 1.4587; Me, Pr, Bu, H, H, H, 1.4603; Me, Pr, Bu, H, Me, H, 1.4594; Me, Pr, Bu, H, Me, Me, 1.4612. This study involved multiple reactions and reactants, such as 2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4SDS of cas: 115-84-4).

2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.SDS of cas: 115-84-4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

O-Alkyl substituted hydroxycarbamates was written by Major, Randolph T.;Dursch, Friedrich;Hess, Hans Jurgen. And the article was included in Journal of Organic Chemistry in 1959.Computed Properties of C9H20O2 The following contents are mentioned in the article:

Some O-alkyl substituted hydroxylamine derivatives possess pharmacol. properties similar to those of related amines. HONHCO₂Et (I), the related compound MeONHCSOEt (II) and various 2,2-dialkyl-1,3-propanediol bis(alkoxyalkylcarbamates), RR¹C(CHOCONR²OR³)₂ (III) were prepared Finely powd. HONH₂.HCl(195 g.) and anhydrous K₂CO₃ (380 g.) stirred in 1500 mL. Et₂O with addition of 20 mL. H₂O, the cooled (ice bath) mixture stirred 1 h. with gradual addition of 300 g. ClCO₂Et (immediate evolution of CO₂) and then overnight at room temperature, the filtered solution evaporated in a slight vacuum and the residue distilled through a 15-cm. Vigreux column in vacuo yielded 66% I, b₃ 113-16°, giving a deep purple color with aqueous FeCl₃. ClCH₂CO₂H (39 g.) slowly neutralized with 17 g. NaOH in 180 mL. ice-cold H₂O and the solution added to 0.30 mol aqueous EtOCS₂Na, the mixture kept overnight and concentrated to 150 mL. in vacuo on a steam bath, the cooled concentrate treated with 21 g. MeONH₂ and the mixture kept overnight, neutralized with AcOH and extracted with Et₂O, the dried (Na₂SO₄) extract evaporated at room temperature and the residual solid (37 g.) recrystallized (petr. ether, b. 30-60°) yielded 66% II, m. 33-6°. Freshly distilled COCl₂ (16.0 g.) in 400 mL. dry PhMe slowly added to 220 g. 1,5-dimethyl-2-phenyl-3-pyrazolone and 70 g. Me₂C(CH₂OH)₂ in 50 mL. CHCl₃ at – 10 to 0° (ice-NaCl bath) and the mixture stirred overnight at room temperature, filtered from antipyrine-HCl (almost quant. yield) and the salt washed with Et₂O, the combined filtrates evaporated in vacuo and the yellow oily residue distilled yielded 2,2-dimethyl-1,3-propanediol bis(chloroformate), RR¹C(CH₂OCOCl)₂ (IV, R = R¹ = Me) (V). Similarly were prepared the analogous IV (R, R¹, b.p./mm., and % yield given): Me, Me, 122-5°/17, 56; Et, Et (VI), 153-5°/24, 64; Et, Bu, 165-8°/20, 60. MeONHMe (3.0 g.) and 5.0 g. powd. anhydrous K₂CO₃ stirred in 30 mL. absolute Et₂O (ice-cooling) with gradual addition of 5.0 g. V (slow evolution of CO₂), and the mixture stirred 24 h. at room temperature, the Et₂O evaporated and the residue taken up in 25 mL. H₂O, extracted with Et₂O and the oily product distilled yielded 86% III (R = R¹ = R² = R³ = Me) (method A). VI (25.7 g.) in 150 mL. absolute Et₂O treated dropwise with 30.5 g. MeON HMe with shaking and cooling, the mixture kept overnight at room temperature and filtered from MeONHMe.HCl, the washed (25 mL. H₂O) and dried (Na₂SO₄) filtrate evaporated and the oily residue distilled yielded 60% III (R = R¹ = Et, R² = R³ = Me) (method B). Similarly were prepared the carbamates III (R, R¹, R², R³, method and b.p./mm. given): Me, Me, Me, Me (VII), A, 183-4°/20; Me, Me, H, Me (VIII), A, 194-5°/1.0; Me, Me, Et, Et (IX), B, 136-8°/0.15; Me, Me, H, Et (X), B, 175-80°/0.5; Et, Et, Me, Me (XI), B, 163-5°/0.3; Et, Et, Et, Et, B, 133.8°/0.1; Et, Bu, Me, Me (XII), B, 166-9°/0.3; Et, Bu, Et, Et, B, 142.8°/0.2. None of the compounds I, MeONHCO₂Et, EtONHCO₂Et (XIII), II, VIII, X, and XII inhibited Sarcoma 180 in vivo at non-toxic doses. XIII showed little effect in mice (i.p. in Mazola oil) in doses below the toxic level of 441 mg./kg. but EtONEtCO₂Et (XIV) produced depression at or near the lethal level of 1069 mg./kg. XIV (1% suspension in tragacanth) abolished the corneal reflex 18 min. on instillation into the rabbit eye. VIII-XII were inactive in tests designed to test their activity in mice similar to that produced by meprobamate. This study involved multiple reactions and reactants, such as 2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4Computed Properties of C9H20O2).

2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Computed Properties of C9H20O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《Experimental investigation and comparison of bio-oil from hybrid microalgae via super/subcritical liquefaction》 was written by Xu, Yufu; Liu, Kai; Hu, Yuanhua; Dong, Yinghui; Yao, Lulu. Quality Control of 3-Pyridinemethanol And the article was included in Fuel in 2020. The article conveys some information:

The development of liquid bioenergy bio-oil from microalgae has recently attracted much attention, while most of them focused on single feedstock. Super/subcritical liquefaction was applied for bio-oil production from hybrid microalgae. The effects of liquefaction conditions on yield of products were studied. The hybrid microalgae Chlorella and Spirulina with an appropriate mass ratio present synergistic effects for liquefaction. La oxide as catalysts in hydrothermal liquefaction system can improve the quality of the bio-oil. Supercritical alc. liquefaction systems have much higher bio-oil yield, and the maximum yield of bio-oil reaches 74.71%. The solvent MeOH and EtOH in supercritical conditions could upgrade the components of the bio-oils and enhance their combustion performances. The comprehensive properties of the bio-oil from hybrid microalgae under supercritical liquefaction conditions show a potential prospect for application. In addition to this study using 3-Pyridinemethanol, there are many other studies that have used 3-Pyridinemethanol(cas: 100-55-0Quality Control of 3-Pyridinemethanol) was used in this study.

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridine is a relatively complex molecule and exhibits a number of different bands in IR spectra. Among others, the bands characterizing the ν8a and ν19b modes have been found to be sensitive to the coordination or protonation of the molecule. Note that the band that is diagnostic for the PyH+ ion at about 1545 cm− 1 (ν19b mode) does not overlap with any of the other bands.Quality Control of 3-Pyridinemethanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Liu, Qing; Ding, Jierong; Huang, Wenjie; Yu, Hang; Wu, Shaowen; Li, Wenyan; Mao, Xingxue; Chen, Wenfeng; Xing, Junlian; Li, Chen; Yan, Shijuan published their research in Rice on December 31 ,2022. The article was titled 《OsPP65 Negatively Regulates Osmotic and Salt Stress Responses Through Regulating Phytohormone and Raffinose Family Oligosaccharide Metabolic Pathways in Rice》.Related Products of 54-17-1 The article contains the following contents:

Although type 2C protein phosphatases (PP2Cs) have been demonstrated to play important roles in regulating plant development and various stress responses, their specific roles in rice abiotic stress tolerance are still largely unknown. In this study, the functions of OsPP65 in rice osmotic and salt stress tolerance were investigated. Here, we report that OsPP65 is responsive to multiple stresses and is remarkably induced by osmotic and salt stress treatments. Significantly higher induction of genes involved in jasmonic acid (JA) and abscisic acid (ABA) biosynthesis or signaling, as well as higher contents of endogenous JA and ABA, were observed in the OsPP65 knockout plants compared with the wild-type plants after osmotic stress treatment. Further anal. indicated that JA and ABA function independently in osmotic stress tolerance conferred by loss of OsPP65. Moreover, metabolomics anal. revealed higher endogenous levels of galactose and galactinol but a lower content of raffinose in the OsPP65 knockout plants than in the wild-type plants after osmotic stress treatment. These results together suggest that OsPP65 neg. regulates osmotic and salt stress tolerance through regulation of the JA and ABA signaling pathways and modulation of the raffinose family oligosaccharide metabolism pathway in rice. OsPP65 is a promising target for improvement of rice stress tolerance using gene editing. In the experiment, the researchers used rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol(cas: 54-17-1Related Products of 54-17-1)

rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol(cas: 54-17-1) is oxidized in various tissues under either aerobic or anaerobic conditions through glycolysis; the oxidation reaction produces carbon dioxide, water, and ATP.Related Products of 54-17-1

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2017,Hu, Lei; Lu, Yue; Li, Xiaona; Liang, Jianwen; Huang, Tao; Zhu, Yongchun; Qian, Yitai published 《Optimization of Microporous Carbon Structures for Lithium-Sulfur Battery Applications in Carbonate-Based Electrolyte》.Small published the findings.Computed Properties of C4H12KNaO10 The information in the text is summarized as follows:

Developing appropriate sulfur cathode materials in carbonate-based electrolyte is an important research subject for lithium-sulfur batteries. Although several microporous carbon materials as host for sulfur reveal the effect, methods for producing microporous carbon are neither easy nor well controllable. Moreover, due to the complexity and limitation of microporous carbon in their fabrication process, there has been rare investigation of effect on electrochem. behavior in the carbonate-based electrolyte for lithium-sulfur batteries by tuning different micropore size(0-2 nm) of carbon host. Here, an immediate carbonization process, self-activation strategy, is demonstrated which can produce microporous carbon for a sulfur host from alkali-complexes. Besides, by changing different alkali-ion in the previous complex, the obtained microporous carbon exhibits a major portion of ultramicropore (< 0.7 nm, from 54.9-25.8%) and it is demonstrated that the micropore structure of the host material plays a vital role in confining sulfur mol. When evaluated as cathode materials in a carbonate-based electrolyte for Li-S batteries, such microporous carbon/sulfur composite can provide high reversible capacity, cycling stability, and good rate capability. The experimental part of the paper was very detailed, including the reaction process of Potassium sodium (2R,3R)-2,3-dihydroxysuccinate tetrahydrate(cas: 6381-59-5Computed Properties of C4H12KNaO10)

Potassium sodium (2R,3R)-2,3-dihydroxysuccinate tetrahydrate(cas: 6381-59-5) is a ferroelectric crystal with a high piezoelectric effect and electromechanical coupling coefficient. Computed Properties of C4H12KNaO10 It may be used as a constituent to prepare DNS (3,5- dinitrosalicylic acid) reagent and Fehling′s solution B, which are used in the determination of reducing sugar.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Safety of 6-Aminohexan-1-olIn 2019 ,《Three-Component Sequential Reactions for Polymeric Nanoparticles with Tailorable Core and Surface Functionalities》 appeared in Chem. The author of the article were Liu, Bin; Thayumanavan, S.. The article conveys some information:

Efficient strategies for the preparation of nanostructures with tailorable functionalities have implications in enhancing the repertoire of nanomaterials in many applications. Multi-component reactions (MCRs) are very attractive because they are synthetically simple while providing unique access to incorporation of functional groups onto a system. This highly efficient process has not been brought to bear in the preparation of functional polymeric nanostructures. In this paper, we report a three-component sequential reaction that is capable of concurrently functionalizing the core and the surface of the nanoparticles and crosslinking the polymeric assemblies, along with excellent control over size (~10 nm to ~1μm). Variations in core offer the opportunity to optimize the host-guest properties for non-covalent drug encapsulation, while the surface features provide the ability to tune interfacial interactions and achieve organelle targeting in cells. Encapsulation of drug mols. and their triggered release features have been utilized for intracellular drug delivery. In the experiment, the researchers used 6-Aminohexan-1-ol(cas: 4048-33-3Safety of 6-Aminohexan-1-ol)

6-Aminohexan-1-ol(cas: 4048-33-3) can undergo cyclization over copper supported on γ-alumina and magnesia to form hexahydro-1H-azepine. It may be used along with glutaric acid to generate poly(ester amide)s with excellent film- and fiber forming properties.Safety of 6-Aminohexan-1-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synthetic Route of C3H9NO2In 2019 ,《Towards mechanical robust yet self-healing polyurethane elastomers via combination of dynamic main chain and dangling quadruple hydrogen bonds》 was published in Polymer. The article was written by Hu, Jin; Mo, Ruibin; Jiang, Xiang; Sheng, Xinxin; Zhang, Xinya. The article contains the following contents:

One of the greatest challenges of robust self-healing materials is the confliction between high chain mobility for self-healing and a stable structure for mech. strength. Herein, dangling 2-ureido-4[1H]-pyrimidione (UPy)-functionalized side groups were introduced into the hard segments of thermoplastic polyurethane (TPU) elastomers, where embedded the dynamic disulfide bonds in the main chain. The strong quadruple H-bonding interaction between UPy side groups acts as supramol. crosslinkers enabling the TPU elastomer to have improved mech. properties (tensile strength up to 25 MPa and toughness ∼100 MJ m-3), and simultaneously the plasticizer effect of dangling side chain endows it with efficient healing ability at elevated temperatures (80-100 °C) comparable to its linear analogs. This strategy shows great potential in designing robust self-healing TPU elastomer employing weak dynamic covalent bonds, with wide promising applications as wearable electronics, coatings and adhesives. In addition to this study using 2-Aminopropane-1,3-diol, there are many other studies that have used 2-Aminopropane-1,3-diol(cas: 534-03-2Synthetic Route of C3H9NO2) was used in this study.

2-Aminopropane-1,3-diol(cas: 534-03-2) belongs to anime. In organic chemistry, amines are compounds and functional groups that contain a basic nitrogen atom with a lone pair. Amines are formally derivatives of ammonia (NH3), wherein one or more hydrogen atoms have been replaced by a substituent such as an alkyl or aryl group (these may respectively be called alkylamines and arylamines; amines in which both types of substituent are attached to one nitrogen atom may be called alkylarylamines).Synthetic Route of C3H9NO2

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Alcohol – Wikipedia,
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《Visible-Light-Induced Nickel-Catalyzed Cross-Coupling with Alkylzirconocenes from Unactivated Alkenes》 was published in Chem in 2020. These research results belong to Gao, Yadong; Yang, Chao; Bai, Songlin; Liu, Xiaolei; Wu, Qingcui; Wang, Jing; Jiang, Chao; Qi, Xiangbing. Application of 821-41-0 The article mentions the following:

Visible-light-induced single nickel-catalyzed C(sp3)-C(sp3), C(sp3)-C(sp2) and C(sp3)-C(sp) cross-coupling reactions were reported using alkylzirconocenes, which were easily generated in-situ from terminal or internal unactivated alkenes through hydrozirconation and chain walking. This method was mild and applicable for a large range of substrates including primary, secondary, tertiary alkyl, aryl, alkenyl, alkynyl halides and a variety of alkenes. Mechanistic studies suggested a novel nickel-catalyzed radical cross-coupling pathway, which represented the first visible-light-induced transformation of alkylzirconocenes. The experimental process involved the reaction of 5-Hexen-1-ol(cas: 821-41-0Application of 821-41-0)

5-Hexen-1-ol(cas: 821-41-0) is a volatile organic compound. Further, it is used to prepare 6-bromo-hex-1-ene by reaction with phosphorus tribromide.Application of 821-41-0

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts