Month: October 2022

Wang, Xiaoda; Gao, Yuan; Li, Chaoqun; Huang, Zhixian; Qiu, Ting published the artcile< Liquid-Liquid Equilibria for the Ternary Systems of Water + Thioglycolic Acid + 2-Ethyl-1-hexyl Thioglycolate and Water + 2-Ethyl-1-hexyl Thioglycolate + 2-Ethyl-1-hexanol at 293.15, 303.15, and 313.15 K under 101 kPa>, Formula: C8H18O, the main research area is liquid equilibrium ternary system; water thioglycolic acid ethylhexyl thioglycolate ethylhexanol.

Liquid-liquid equilibrium data were determined for the two ternary systems of water + thioglycolic acid (TGA) + 2-ethyl-1-hexyl thioglycolate (ETE) and water + 2-ethyl-1-hexyl thioglycolate (ETE) + 2-ethyl-1-hexanol (EHL) at 293.15, 303.15, and 313.15 K under 101 kPa. The nonrandom two-liquid (NRTL) and universal quasi-chem. (UNIQUAC) activity coefficient models were used to correlate the exptl. LLE data. The LLE data calculated by the NRTL and UNIQUAC models were in good agreement with the exptl. ones.

Journal of Chemical & Engineering Data published new progress about Liquid-liquid equilibrium. 104-76-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H18O, Formula: C8H18O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Xu, Jing-xiu; Pan, Nan-lian; Chen, Jia-xi; Zhao, Jin-wu published the artcile< Visible-light-mediated oxidative cyclization of 2-aminobenzyl alcohols and secondary alcohols enabled by an organic photocatalyst>, Computed Properties of 5344-90-1, the main research area is photocatalysis photocyclization benzyl alc quinoline.

This paper describes a visible-light-mediated oxidative cyclization of 2-aminobenzyl alcs. and secondary alcs. to produce quinolines at room temperature This photocatalytic method employed anthraquinone as an organic small-mol. catalyst and DMSO as an oxidant. According to this present procedure, a series of quinolines were prepared in satisfactory yields.

Journal of Organic Chemistry published new progress about Aralkyl alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Computed Properties of 5344-90-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yang, Lichen; Uemura, Nao; Nakao, Yoshiaki published the artcile< meta-Selective C-H Borylation of Benzamides and Pyridines by an Iridium-Lewis Acid Bifunctional Catalyst>, Related Products of 660867-80-1, the main research area is meta selective borylation benzamide pyridine iridium aluminum bifunctional catalyst; borane pyridyl benzamide derivative preparation.

The authors report herein the Ir-catalyzed meta-selective C-H borylation of benzamides by using a newly designed 2,2′-bipyridine (bpy) ligand bearing an alkylaluminum biphenoxide moiety. The authors also demonstrate the Ir-catalyzed C3-selective C-H borylation of pyridine with a 1,10-phenanthroline (Phen) ligand bearing an alkylborane moiety. Probably the Lewis acid-base interaction between the Lewis acid moiety and the aminocarbonyl group or the sp2-hybridized N atom accelerates the reaction and controls the site-selectivity.

Journal of the American Chemical Society published new progress about Benzamides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 660867-80-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C12H18BNO2, Related Products of 660867-80-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Munoz-Gonzalez, Carolina; Canon, Francis; Feron, Gilles; Guichard, Elisabeth; Pozo-Bayon, Maria Angeles published the artcile< Assessment wine aroma persistence by using an in vivo PTR-ToF-MS approach and its relationship with salivary parameters>, Formula: C10H18O, the main research area is wine aroma persistence salivary parameter; PTR-ToF-MS; commercial tannin extracts; in vivo aroma release; interindividual differences; saliva; wine aroma persistence.

To better understand wine aroma persistence, the nasal cavity of nine volunteers was monitored by Proton Transfer Reaction-Time of Flight-Mass Spectrometry (PTR-ToF-MS) after they rinsed their mouths with three rose wines (one control and the same wine supplemented with two tannin extracts) during four minutes. Wines were aromatized with a mixture of five target aroma compounds Results showed that wine aroma persistence was highly compound-dependent: while esters disappeared very fast, other compounds such as linalool remained in the oral cavity for longer times after wine expectoration. A low effect of tannins (at 50 mg/L) on nasal cavity parameters was observed, with the exception for the compound Et decanoate that was significantly higher released in the presence of tannins. Strong interindividual differences on aroma persistence were also found. Significant pos. correlations with the salivary total protein content and neg. with the salivary flow were observed for specific compounds This work has studied for the first time in vivo wine aroma persistence in real time from an anal. perspective.

Molecules published new progress about Decay (biological). 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, Formula: C10H18O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Fu, Yuan; Yuan, Qin; Lin, Shang; Liu, Wen; Du, Gang; Zhao, Li; Zhang, Qing; Lin, De-Rong; Liu, Yun-Tao; Qin, Wen; Li, De-Qiang; Wu, Ding-Tao published the artcile< Physicochemical characteristics and biological activities of polysaccharides from the leaves of different loquat (Eriobotrya japonica) cultivars>, Formula: C6H12O6, the main research area is Eriobotrya leaf physicochem polysaccharide; Binding properties; Enzyme inhibition; Eriobotrya japonica; Loquat; Polysaccharides; Weight-average molecular weights.

In order to explore polysaccharides from loquat leaves (LLPs) as functional food ingredients for prevention and treatment of obesity and type 2 diabetes, the physicochem. characteristics, in vitro binding properties, and inhibitory effects on α-amylase and α-glucosidase of polysaccharides from the leaves of different loquat cultivars, including ‘Baiyu’, ‘Chuannong8’, ‘Yuanbao’, and ‘Dawuxing’, were investigated and compared. Results showed that the contents of total uronic acids and degree of esterification in LLPs ranged from (27.04 ± 1.76)% to (41.46 ± 1.91)%, and from (20.54 ± 0.11)% to (26.90 ± 0.10)%, resp. The weight-average mol. weights of LLPs ranged from 4.307 × 106 Da to 5.101 × 106 Da, and the major constituent monosaccharides of LLPs were rhamnose, galacturonic acid, arabinose, and galactose. Furthermore, LLPs exerted strong in vitro fat binding, cholesterol binding, and bile acid binding capacities, as well as remarkable inhibitory effects on α-amylase and α-glucosidase, which might be attributed to their mol. weights, mol. weight distributions, and degree of esterification. Results are helpful for better understanding of chem. structures and bioactivities of polysaccharides from loquat leaves, and LLPs had good potential to be explored as functional food ingredients for prevention and treatment of obesity and type 2 diabetes.

International Journal of Biological Macromolecules published new progress about Bile acids Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 3458-28-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Formula: C6H12O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Singh, Vivek Kumar; Donthireddy, S. N. R.; Pandey, Vipin K.; Rit, Arnab published the artcile< RuII-Complexes of heteroditopic chelating NHC ligands: effective catalysts for the β-alkylation of secondary alcohols and the synthesis of 2-alkylaminoquinoline derivatives following the dehydrogenative protocol>, Application In Synthesis of 5344-90-1, the main research area is ruthenium NHC imidazolylidene triazolylidene cymene complex preparation coupling catalyst; coupling primary secondary alc preparation aralkyl alc ruthenium catalyst; quinoline amine preparation cyclization amino alc nitrile ruthenium catalyst.

RuII-Complexes of chelating heteroditopic N-heterocyclic carbene ligands I·BF4 (1a-c; R = 2,4,6-Me3, 4-OMe, 4-CF3) featuring imidazol-2-ylidene (ImNHC) and 1,2,3-triazol-5-ylidene (tzNHC) donors connected via a CH2 spacer, were found to be very effective catalysts for the cross-coupling of secondary alcs. ArCH(OH)Me and primary alcs. RCH2OH with the elimination of H2O, yielding aralkyl alcs. ArCH(OH)CH2CH2R (Ar = substituted Ph, 2-naphthyl, 2-thienyl; R = aryl, hetaryl, C5H11). Diverse β-alkylated secondary alcs. were thus obtained by following this method in excellent yields of up to 95% by employing a very low catalyst 1a loading of 0.01-0.001 mol% along with the inexpensive base KOH. Mechanistically, the present protocol follows the borrowing hydrogen strategy which was established by various control experiments including deuterium labeling experiments and importantly, 1H NMR and ESI-MS analyses validated the participation of a Ru-H species in the catalytic cycle. Remarkably, the present system displayed the highest Ru-based TON of 396 000 for the β-benzylation of 1-phenylethanol with a catalyst loading of 1 ppm (0.0001 mol%). Addnl., diverse 2-alkylaminoquinoline derivatives were synthesized in a one-pot manner from 2-aminobenzyl alc., 2-arylacetonitrile, and various primary alcs.

Organic & Biomolecular Chemistry published new progress about Alkylation. 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Application In Synthesis of 5344-90-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Azizi, Kobra; Akrami, Sedigheh; Madsen, Robert published the artcile< Manganese(III) Porphyrin-Catalyzed Dehydrogenation of Alcohols to form Imines, Tertiary Amines and Quinolines>, Application of C7H9NO, the main research area is manganese porphyrin chloride catalyst dehydrogenative coupling alcs amine; imine synthesis; tertiary amine synthesis; quinoline synthesis; alcohols; dehydrogenation; homogeneous catalysis; manganese; synthetic methods.

Manganese(III) porphyrin chloride complexes have been developed for the first time as catalysts for the acceptorless dehydrogenative coupling of alcs. and amines. The reaction has been applied to the direct synthesis of imines, tertiary amines and quinolines where only hydrogen gas and/or water are formed as the byproduct(s). The mechanism is believed to involve the formation of a manganese(III) alkoxide complex which degrades into the aldehyde and a manganese(III) hydride species. The latter reacts with the alc. to form hydrogen gas and thereby regenerates the alkoxide complex.

Chemistry – A European Journal published new progress about Aliphatic alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Application of C7H9NO.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhao, Hui; Gao, Kai; Ma, Haichen; Yip, Tsz Chun; Dai, Wei-Min published the artcile< Synthesis of the C19-C30 bis-THF fragment of iriomoteolide-13a via stepwise SN2 cyclization and intramolecular syn-oxypalladation>, Application In Synthesis of 627-27-0, the main research area is iriomoteolide fragment preparation; alkyne cyclization asym dihydroxylation.

The C19-C30 bis-THF fragment I [stereo = R or S] of the proposed structure of iriomoteolide-13a were synthesized. The ω-mesyloxy-substituted stereotetrad possessing three continuous hydroxy groups was generated by an anti-aldol reaction and asym. dihydroxylation was the key steps. Upon heating in pyridine, the stereotetrad underwent an SN2 cyclization to form the C19-C22 THF ring chemoselectively. The propargylic alc., after cleavage of the C28-OPMB ether, was reduced to the corresponding allylic alc. with spontaneous removal of the C23-OTBS protecting group. Finally, the ene triol was subjected to the Pd(II)-catalyzed intramol. syn-oxypalladation to give the C23-C26 THF ring. It was found that the C21-OH group, which might form a chelated Pd(II) complex along with the C23-OH group, was tolerated during the syn-oxypalladation process.

Organic Chemistry Frontiers published new progress about Cyclization, stereoselective. 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Application In Synthesis of 627-27-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Hai-ou; Liu, Si-hong; Zhou, Xue-jie; Yang, Xiao-yue; Gao, Qi; Tanokura, Masaru; Xue, You-lin published the artcile< Treatment with hydrogen peroxide improves the physicochemical properties of dietary fibres from Chinese yam peel>, Computed Properties of 492-62-6, the main research area is hydrogen peroxide Chinese yam peel dietary fiber physicochem property.

Summary : Yam is a common ‘medicine food homol.’ vegetable in Asia, and its peel is often considered a food residue during processing or cooking. In this work, the effects of hydrogen peroxide modification on the dietary fibers (DFs) from Chinese yam peel (CYP) were investigated. The structural characteristics of soluble dietary fiber (SDF), insoluble dietary fiber (IDF), modified soluble dietary fiber (MSDF) and modified insoluble dietary fiber (MIDF) were analyzed using Fourier-transform IR spectroscopy, X-ray diffraction, differential scanning calorimetry, granularity anal., SEM and GC-MS (monosaccharide composition). As results, after modification with hydrogen peroxide, the sizes of the DFs were reduced and MIDF exposed more cellulose. Experiments on the physicochem. and functional properties of DFs showed that MSDF and MIDF obtained a better water holding capacity, oil absorption capacity, swelling capacity and absorption abilities with altered structures, which is of great importance in food processing and development.

International Journal of Food Science and Technology published new progress about Crystallinity. 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Computed Properties of 492-62-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hu, Guodong; Zhong, Miao; Zhao, Jintao; Gao, Hao; Gan, Lu; Zhang, Hong; Zhang, Shengxiang; Fang, Jianguo published the artcile< Fluorescent Probes for Imaging Protein Disulfides in Live Organisms>, Product Details of C19H16O, the main research area is fluorescent probe imaging protein disulfide in vivo; environment-sensitive probes; fluorescent probes; in vivo imaging; mouse stroke model; protein disulfides; two-photon.

Cellular redox homeostasis is predominantly controlled by the ratio of thiols and disulfides, and reversible thiol-disulfide exchange reactions are fundamental of the biol. redox regulation. However, due to the dynamic exchanges of thiols and disulfides, the detection, especially the in situ detection, of protein disulfides (PDS) is challenging. We employ the strategy, i.e., the increase of emission upon an environment-sensitive dye binding to proteins, to design PDS probes and discover a two-photon probe PDSTP590 (S6) (I) that selectively recognizes PDS in live organisms. With the aid of the probe, we further disclose the elevation of PDS in brains of the mouse stroke model.

ACS Sensors published new progress about Bovine serum albumin Role: ANT (Analyte), BSU (Biological Study, Unclassified), ANST (Analytical Study), BIOL (Biological Study). 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Product Details of C19H16O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts