Month: October 2022

In 2019,Acta Crystallographica, Section E: Crystallographic Communications included an article by Wiedemann, Dennis; Kulko, Roman-David; Grohmann, Andreas. Category: alcohols-buliding-blocks. The article was titled 《Synthesis, characterization, and crystal structure of aquabis(4,4′-dimethoxy-2,2′-bipyridine)[μ-(2R,3R)-tartrato(4-)]dicopper(II) octahydrate》. The information in the text is summarized as follows:

Typical electroless copper baths (ECBs), which are used to chem. deposit copper on printed circuit boards, consist of an aqueous alkali hydroxide solution, a copper(II) salt, formaldehyde as reducing agent, an L-(+)-tartrate as complexing agent, and a 2,2-bipyridine derivative as stabilizer. Actual speciation and reactivity are, however, largely unknown. Herein, we report on the synthesis and crystal structure of aqua-1κO-bis(4,4-dimethoxy-2,2-bipyridine)-1κ2N,N;2κ2N,N-[μ-(2R,3R)-2,3-dioxidosuccinato-1κ2O1,O2:2κ2O3,O4]dicopper(II) octahydrate, [Cu2(C12H12N2O2)2(C4H2O6)(H2O)]·8H2O, from an ECB mock-up. The title compound crystallizes in the Sohncke group P21 with one chiral dinuclear complex and eight mols. of hydrate water in the asym. unit. The expected retention of the tartrato ligand′s absolute configuration was confirmed via determination of the absolute structure. The complex mols. exhibit an ansa-like structure with two planar, nearly parallel bipyridine ligands, each bound to a copper atom that is connected to the other by a bridging tartrato ′handle′. The complex and water mols. give rise to a layered supramol. structure dominated by alternating π stacks and hydrogen bonds. The understanding of structures ex situ is a first step on the way to prolonged stability and improved coating behavior of ECBs.Potassium sodium (2R,3R)-2,3-dihydroxysuccinate tetrahydrate(cas: 6381-59-5Category: alcohols-buliding-blocks) was used in this study.

Potassium sodium (2R,3R)-2,3-dihydroxysuccinate tetrahydrate(cas: 6381-59-5) is a ferroelectric crystal with a high piezoelectric effect and electromechanical coupling coefficient. Category: alcohols-buliding-blocks Potassium sodium tartrate tetrahydrate has been used in the preparation of Lowry reagent for the determination of microsomal protein concentration in rat hepatic microsomes by Lowry method.

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《Magnetic dextrin nanobiomaterial: An organic-inorganic hybrid catalyst for the synthesis of biologically active polyhydroquinoline derivatives by asymmetric Hantzsch reaction》 was written by Maleki, Ali; Hassanzadeh-Afruzi, Fereshte; Varzi, Zahra; Esmaeili, Mir Saeed. Related Products of 100-83-4 And the article was included in Materials Science & Engineering, C: Materials for Biological Applications in 2020. The article conveys some information:

Magnetic dextrin nanobiocomposite was prepared and used as a green organocatalyst. Subsequently, to evaluate the catalytic performance of the synthetic hybrid catalyst, it was tested for the synthesis of biol. active polyhydroquinoline derivatives I [Ar = Ph, 4-MeC6H4, 4-ClC6H4, etc.] by four-component condensation reactions of aromatic aldehyde, Et acetoacetate, dimedone, ammonium acetate in ethanol under refluxing conditions. Exptl. observations indicated some advantages of the present method, such as the use of green and biopolymer-based catalyst, simple procedure, mild reaction conditions, short reaction times (15-45 min), appropriate yield of products (70-95%) and catalyst reusability after five consecutive runs without considerable catalytic performance decrease. In the experiment, the researchers used many compounds, for example, 3-Hydroxybenzaldehyde(cas: 100-83-4Related Products of 100-83-4)

3-Hydroxybenzaldehyde(cas: 100-83-4) is used as an ionophore, during the development of an highly selective and sensitive PVC membrane sensor, which can be used as a Tb3+ ion selective electrode.Related Products of 100-83-4

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Alcohol – Wikipedia,
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Gampa, Muralimohan; Padmaja, Pannala; Aravind, Seema; Reddy, Pedavenkatagari Narayana published an article in 2021. The article was titled 《An efficient one-pot synthesis of indolyl-4H-chromene derivatives》, and you may find the article in Chemistry of Heterocyclic Compounds (New York, NY, United States).Category: alcohols-buliding-blocks The information in the text is summarized as follows:

A new one-pot three-component reaction for the synthesis of indolyl-4H-chromene derivatives I (R1 = H, 6-Cl, 6-Br, 6,8-(Cl)2; R2 = 2-Me, 5-OH, 6-Br, etc.; R3 = CH, N) has been developed. The synthesis was achieved by reacting salicylaldehydes 1-CHO-2-OHC6H3R1 (R1 = H, 5-Cl, 5-Br, 3,5-Cl2), (E)-N-methyl-1-(methylsulfanyl)-2-nitroethenamine, and indoles II in the absence of solvent using triethylamine as a catalyst. The final products I were isolated by precipitation after the addition of ethanol to the reaction mixture This transformation involves the formation of indole-substituted chromene ring by creation of two C-C bonds and one C-O bond in a single synthetic operation. This rapid one-pot reaction does not require chromatog. purification and provides the indolyl-4H-chromene derivatives I in good yields. The experimental process involved the reaction of Oxetan-3-ol(cas: 7748-36-9Category: alcohols-buliding-blocks)

Oxetan-3-ol(cas: 7748-36-9) is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.Category: alcohols-buliding-blocks

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Shen, Wenbo; Liu, Jiaoshi; Du, Bin; Zhuo, Haitao; Chen, Shaojun published an article in 2021. The article was titled 《Thermal- and light-responsive programmable shape-memory behavior of liquid crystalline polyurethanes with pendant photosensitive groups》, and you may find the article in Journal of Materials Chemistry A: Materials for Energy and Sustainability.Synthetic Route of C3H7BrO The information in the text is summarized as follows:

In this study, a liquid crystalline polyurethane that exhibits thermal- and light-responsive programmable shape-memory behavior was prepared via the quaternization reaction between a mesogenic azobenzene compound and a conventional polyurethane (PU). In the film, the variation in the configuration of mesogenic azobenzene units afforded the internal stress to actuate the motion of the polymer chains and induced the chains to adopt a coiled conformation, leading to the macroscopic deformation of the film under light stimulation. The hard segments of PU provided the skeleton that froze the conformation of the polymer chains and ensured that the temporary shape was maintained after removing the stimuli. The variation of the tensile stress required for maintaining the elongation of the film under different stimuli was measured, and a possible mechanism for the multiple stimuli-responsive shape deformation of the material from the point of view of the evolution of polymer chain conformations was also discussed. Moreover, flexible photomech. devices based on the liquid crystalline polyurethane film were fabricated, and the soft devices could catch an object even in the absence of stimuli. This work can provide a creative route for the fabrication and practical application of novel photomech. devices and soft robotics more in line with the requirements of energy-saving and intelligence. After reading the article, we found that the author used 3-Bromopropan-1-ol(cas: 627-18-9Synthetic Route of C3H7BrO)

3-Bromopropan-1-ol(cas: 627-18-9) is used in the synthesis of fluorescent halide-sensitive quinolinium dyes, chiral, quaternary prolines through cyclization of quaternary amino acids and molten salt-polymers. It is utilized for the study of micellar media and in microemulsions based on cationic or a nonionic surfactant by reacting with phenols.Synthetic Route of C3H7BrO

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Computed Properties of C7H6O3In 2021 ,《A simple strategy for simultaneously enhancing photostability and mitochondrial-targeting stability of near-infrared fluorophores for multimodal imaging-guided photothermal therapy》 appeared in Journal of Materials Chemistry B: Materials for Biology and Medicine. The author of the article were Zhang, Shuping; Chen, Hua; Wang, Liping; Liu, Chunli; Liu, Li; Sun, Yu; Shen, Xing-can. The article conveys some information:

Near-IR fluorophores are emerging as promising mol. tools for cancer theranostics because of their inherent biodegradability, low toxicity, and synthetic flexibility. However, they still suffer from several limitations, such as poor photostability and insufficient organelle-targeting stability during photothermal therapy. In this work, we introduce an “”aldehyde functionalization”” strategy for simultaneously enhancing photostability and mitochondria-immobilization of near-IR fluorophores for the first time. Based on the proposed strategy, representative near-IR organic mols., namely AF-Cy, were rationally designed and synthesized. Upon aldehyde modification, the AF-Cy dyes displayed both remarkable photostability and mitochondrial-targeting stability. The strong absorption in the near-IR region confers the AF-Cy dyes with outstanding fluorescent/photoacoustic imaging and photothermal therapy capabilities. Finally, in vitro and in vivo studies revealed the enhanced performance in inhibiting the growth of breast tumors under NIR laser radiation, and these results suggested the strong potential of AF-Cy dyes as efficient multimodal imaging-guided photothermal therapy agents, further highlighting the value of this simple strategy in the design high performance near-IR fluorophores for tumor theranostics. In addition to this study using 3,5-Dihydroxybenzaldehyde, there are many other studies that have used 3,5-Dihydroxybenzaldehyde(cas: 26153-38-8Computed Properties of C7H6O3) was used in this study.

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is a building block. It has been used in the synthesis of 2,4-dimethylbenzoylhydrazones with antileishmanial and antioxidant activities.Computed Properties of C7H6O3

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Synthetic Route of C7H9NO2In 2020 ,《A novel rhodamine-based optical probe for mercury(II) ion in aqueous medium: A nanomolar detection, wide pH range and real water sample application》 appeared in Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy. The author of the article were Patil, Sagar K.; Das, Dipanwita. The article conveys some information:

In present work, we designed and synthesized new chemosensor RPy (I), containing the rhodamine and 2,6-pyridinedicarboxaldehyde functionality, for the selective detection of mercury (II) (Hg2+) ion in aqueous DMSO solvents. The RPy acts as “”turn ON”” probe for Hg2+ ion with high selectivity and sensitivity over the series of other competing metal ions based on colorimetric and fluorimetric techniques. Due to the incorporation of two rhodamine moieties enhance the chelation sites for mercury binding, which reflects in the lowering of the detection limit up to 26 nM. The Job plot method confirms the 1:2 stoichiometric interactions between the RPy and Hg2+ ion. The formation of the chelation complex between RPy and Hg2+ ion with spirolactam ring opening was thoroughly investigated by absorption, emission, 1H NMR, and mass anal. The detection of Hg2+ ion by RPy is retained at broad pH range 4-9. Further, the probe RPy is successfully explored to measure the contamination of Hg2+ ion in the real water samples using spike and recovery method.2,6-Pyridinedimethanol(cas: 1195-59-1Synthetic Route of C7H9NO2) was used in this study.

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridine and pyridine-derived structures are privileged pharmacophores in medicinal chemistry and an essential functionality for organic chemists. As the prototypical π-deficient heterocycle, pyridine illustrates distinctive chemistry as both substrate and reagent. Synthetic Route of C7H9NO2

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The author of 《Novel imine-linked covalent organic frameworks: preparation, characterization and application》 were Wu, Xingchun; Wang, Bowei; Yang, Ziqi; Chen, Ligong. And the article was published in Journal of Materials Chemistry A: Materials for Energy and Sustainability in 2019. Electric Literature of C7H9NO2 The author mentioned the following in the article:

Covalent organic frameworks (COFs) have attracted considerable interest over the past few years, but the available type of monomers is still limited. Herein, two novel imine-linked COFs (TaDAP and TaDA) were constructed by the condensation of 1,3,5-tris-(4-aminophenyl) triazine with 2,6-diformylpyridine (forming TaDAP) and 1,3-benzenedialdehyde (forming TaDA) under solvothermal conditions. The structures of the COFs were confirmed and characterized by solid state 13C NMR, FT-IR, PXRD, TGA, SEM, TEM and nitrogen sorption isotherms. They appear as regular spherical particles and possess excellent thermal stability. It was also found that their dispersions emit strong fluorescence, and display quick response to certain metal ions. In particular, TaDAP can detect Fe3+ with sensitivity and selectivity. Moreover, both the COFs present excellent catalytic activity towards the Knoevenagel reaction. Accordingly, this study not only provides a new way to enrich the family of COFs, but also develops their potential applications in metal ion detection. In the part of experimental materials, we found many familiar compounds, such as 2,6-Pyridinedimethanol(cas: 1195-59-1Electric Literature of C7H9NO2)

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridines form stable salts with strong acids. Pyridine itself is often used to neutralize acid formed in a reaction and as a basic solvent. Electric Literature of C7H9NO2

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《Facile synthesis of a covalently connected rGO-COF hybrid material by in situ reaction for enhanced visible-light induced photocatalytic H2 evolution》 was published in Journal of Materials Chemistry A: Materials for Energy and Sustainability in 2020. These research results belong to Yao, Yu-Hao; Li, Jing; Zhang, Hao; Tang, Hong-Liang; Fang, Liang; Niu, Gu-Dan; Sun, Xiao-Jun; Zhang, Feng-Ming. Electric Literature of C9H6O6 The article mentions the following:

Covalent organic frameworks (COFs) have shown promising visible-light-driven hydrogen evolution activity, but improving the separation and migration of photogenerated electron-hole pairs is still the key point for further increasing their activity. In this work, for the first time, we designed and synthesized a new type of covalently connected rGO-COF photocatalyst for enhanced hydrogen evolution. A series of rGO-TpPa-1-COFs was obtained by a facile one-pot reaction through adding GO to the synthetic system of TpPa-1-COF with DMF as a solvent, which led to the reduction and functionalization of GO and further covalent connection with the COF as confirmed by various characterization techniques. The resulting rGO(5%)-TpPa-1-COF showed a H2 evolution rate of 11.98 mmol g-1 h-1 under visible-light irradiation, which was 4.85 and 2.50 times higher than those of pure TpPa-1-COF and 5%rGO/TpPa-1-COF without any covalent connection between the two components, resp. Further investigations confirmed that the covalent connection between the rGO and TpPa-1-COF components not only served as a “”band”” to tightly combine these two types of 2D material together, but also acted as a “”bridge”” to largely improve the separation of photogenerated charges of the COF as well as the migration of photogenerated electrons to rGO, thus leading to the resulting enhanced H2 evolution activity. The experimental process involved the reaction of 2,4,6-Trihydroxybenzene-1,3,5-tricarbaldehyde(cas: 34374-88-4Electric Literature of C9H6O6)

2,4,6-Trihydroxybenzene-1,3,5-tricarbaldehyde(cas: 34374-88-4) is a member of phloroglucinol derivatives.Electric Literature of C9H6O6For acyl phloroglucinols, it is considered the largest category of compounds among phloroglucinols of natural characteristics.

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In 2019,Journal of Materials Chemistry A: Materials for Energy and Sustainability included an article by Yuan, Jinqiu; Wu, Mengyuan; Wu, Hong; Liu, Yanan; You, Xinda; Zhang, Runnan; Su, Yanlei; Yang, Hao; Shen, Jianliang; Jiang, Zhongyi. Name: 2,4,6-Trihydroxybenzene-1,3,5-tricarbaldehyde. The article was titled 《Covalent organic framework-modulated interfacial polymerization for ultrathin desalination membranes》. The information in the text is summarized as follows:

The demand for thin-film composite nanofiltration membranes bearing unprecedented water permeance and desirable salt rejection is ever increasing in desalination. Conventional interfacial polymerization usually generates a thick (∼100 nm) skin layer on hydrophobic substrate having low-porosity, leading to limited water permeance. Herein, we engineered a highly porous and superhydrophilic composite substrate to modulate the interfacial polymerization and generate an ultrathin polyamide skin layer, even below 10 nm. The composite substrate was constructed by depositing covalent organic framework nanosheets (CONs) on a microfiltration membrane via vacuum-assistant assembly. Owing to the highly porous structure and superhydrophilic nature of CONs, the composite substrate favored a high storage capacity and uniform distribution of the amine monomers. We manipulated the monomer storage capacity of the substrate by varying the loading content of CONs and demonstrated that higher amino monomer concentration could accelerate the self-sealing and self-termination of the interfacial polymerization, thus generating a thinner skin layer from ∼70 nm to sub-10 nm. Moreover, the highly porous structure of CONs imparted little addnl. water transport resistance. The sub-10 nm film composite membrane exhibited a superior water permeance of 535.5 L m-2 h-1 MPa-1 with a high rejection of 94.3% for Na2SO4, which was about 2-8 times higher than that of state-of-the-art nanofiltration membranes with comparable rejection. In addition to this study using 2,4,6-Trihydroxybenzene-1,3,5-tricarbaldehyde, there are many other studies that have used 2,4,6-Trihydroxybenzene-1,3,5-tricarbaldehyde(cas: 34374-88-4Name: 2,4,6-Trihydroxybenzene-1,3,5-tricarbaldehyde) was used in this study.

2,4,6-Trihydroxybenzene-1,3,5-tricarbaldehyde(cas: 34374-88-4) is a member of phloroglucinol derivatives.Name: 2,4,6-Trihydroxybenzene-1,3,5-tricarbaldehydePhloroglucinols are known for their broad-spectrum antiviral, antibacterial, antifungal, antihelminthic, and phytotoxic activities.

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Alcohol – Wikipedia,
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《Covalent organic framework-based ultrathin crystalline porous film: manipulating uniformity of fluoride distribution for stabilizing lithium metal anode》 was published in Journal of Materials Chemistry A: Materials for Energy and Sustainability in 2020. These research results belong to Zhao, Zedong; Chen, Wuji; Impeng, Sarawoot; Li, Mengxiong; Wang, Rong; Liu, Yicheng; Zhang, Long; Dong, Lei; Unruangsri, Junjuda; Peng, Chengxin; Wang, Changchun; Namuangruk, Supawadee; Lee, Sang-Young; Wang, Yonggang; Lu, Hongbin; Guo, Jia. Related Products of 34374-88-4 The article mentions the following:

Lithium metal is regarded as the “”Holy Grail”” for rechargeable batteries yet it still suffers from low coulombic efficiency caused by its high reactivity toward the electrolyte. The so-formed solid-electrolyte interphases (SEIs) are ununiform and sluggish-ion-conducting further inducing severe dendrite growth. Herein, we report the in situ LiF-embedded covalent organic framework (COF) as a novel artificial lithium/electrolyte interphase. Briefly, an electrochem. active COF ultrathin film is synthesized by interfacial aldimine condensation, in which lithiophilic moieties reside in the high-surface-area COF film and can locally concentrate Li-salts from a dilute electrolyte. This promotes the electrochem. in situ formation of anion-derived LiF-rich SEI during the first cycling. Owing to the coaxially oriented microporous channels displayed in the COF, the as-formed LiF grains are confined in the micropores and evenly distributed throughout the COF matrix, thereby enhancing the mech. strength of the SEI against dendrite growth as well as retaining flexibility to tolerate the anode volume change over cycling. Also, the Li+ diffusion pathway is highly ordered along the 1D pore walls of the COF so as to spatially homogenize Li+ flux. Therefore, the LiF-embedded COF interphase exhibits cooperative effectiveness to greatly stabilize the lithium metal anode. The full cell maintains its excellent performances with stable cycling and high efficiency in the close-to-practice conditions. In addition to this study using 2,4,6-Trihydroxybenzene-1,3,5-tricarbaldehyde, there are many other studies that have used 2,4,6-Trihydroxybenzene-1,3,5-tricarbaldehyde(cas: 34374-88-4Related Products of 34374-88-4) was used in this study.

2,4,6-Trihydroxybenzene-1,3,5-tricarbaldehyde(cas: 34374-88-4) is a member of phloroglucinol derivatives.Related Products of 34374-88-4For acyl phloroglucinols, it is considered the largest category of compounds among phloroglucinols of natural characteristics.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts