Tag: M.W=50-100

Filannino, Pasquale published the artcileVolatilome and bioaccessible phenolics profiles in lab-scale fermented bee pollen, Formula: C5H12O, the main research area is fermented bee pollen volatilome bioaccessible phenolics; fermentation; flavonoids; lactic acid bacteria; phenolics; pollen; volatile compounds.

Bee-collected pollen (BCP) is currently receiving increasing attention as a dietary supplement for humans. In order to increase the accessibility of nutrients for intestinal absorption, several biotechnol. solutions have been proposed for BCP processing, with fermentation as one of the most attractive. The present study used an integrated metabolomic approach to investigate how the use of starter cultures may affect the volatilome and the profile of bioaccessible phenolics of fermented BCP. BCP fermented with selected microbial starters (Started-BCP) was compared to spontaneously fermented BCP (Unstarted-BCP) and to unprocessed raw BCP (Raw-BCP). Fermentation significantly increased the amount of volatile compounds (VOC) in both Unstarted- and Started-BCP, as well as modifying the relative proportions among the chem. groups. Volatile free fatty acids were the predominant VOC in Unstarted-BCP. Started-BCP was differentiated by the highest levels of esters and alcs., although volatile free fatty acids were always prevailing. The profile of the VOC was dependent on the type of fermentation, which was attributable to the selected Apilactobacillus kunkeei and Hanseniaspora uvarum strains used as starters, or to the variety of yeasts and bacteria naturally associated to the BCP. Started-BCP and, to a lesser extent, Unstarted-BCP resulted in increased bioaccessible phenolics, which included microbial derivatives of phenolic acids metabolism

Foods published new progress about Aldehydes Role: BSU (Biological Study, Unclassified), PUR (Purification or Recovery), BIOL (Biological Study), PREP (Preparation). 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Formula: C5H12O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Li, Yuguo published the artcileComprehensive chemical characterization of dissolved organic matter in typical point-source refinery wastewaters, Related Products of alcohols-buliding-blocks, the main research area is organic compound petroleum refinery wastewater FTIR GC MS fluorometry; Chemical composition; Dissolved organic matter; EEM; FT-ICR MS; GC-MS; Point-source wastewater.

In petroleum refineries, the elec. desalting, distillation, and stripping processes could generate large amounts of wastewaters that contain toxic substances. In this study, eight wastewater samples were collected from the three typical refining processes for comprehensive chem. characterization of the dissolved organic matter (DOM) using excitation emission matrix fluorescence spectroscopy, gas chromatog.-mass spectrometry, and Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS). Results showed that protein-like components and benzene were ubiquitous in all these wastewaters. Oxygen-containing volatile organic compounds had higher contents in crude distillation and stripping wastewater than those in elec. desalting wastewater. Among the three refinery processes, mol. composition of DOM in the stripping wastewater had the highest complexity. The Ox and OxSy class species assigned from the neg.-ion electrospray ionization FT-ICR MS were dominant in all wastewaters. The OxS2 class species which were effectively removed during stripping treatment had highest relative abundance in stripping influent. These results are instructive to guide the development of ”divide and conquer” and would improve the treatment and management of refinery wastewater streams.

Chemosphere published new progress about Chemical oxygen demand. 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Nagalakshmi, Veerasamy published the artcileSynthesis and characterization of new ruthenium(III) complexes derived from fluoreneamine-based Schiff base ligands and their catalytic activity in transfer hydrogenation of ketones, Category: alcohols-buliding-blocks, the main research area is ruthenium fluoreneamine Schiff base complex preparation transfer hydrogenation catalyst.

An easy and convenient synthesis of a new series of octahedral ruthenium(III) complexes bearing Schiff base ligands of general formula [RuCl2(EPh3)2(L)] (E = P, As and L = O,N-donor Schiff bases) is reported. The composition of all complexes was unequivocally characterized by spectral (IR, UV-visible, EPR) and ESI-MS techniques. The substituted Schiff base ligands behave as bidentate O,N-donors and coordinate to ruthenium via the phenolic oxygen, the azomethine nitrogen. Complexes were proven to catalyze the transfer hydrogenation of linear, cyclic and aromatic ketones to their corresponding secondary alcs. in the presence of i-PrOH/KOH at 80° with conversion up to 99%. The effect of other variables on the transfer hydrogenation reaction such as solvent, base, and catalyst loading is also reported.

Journal of Coordination Chemistry published new progress about Ketones Role: RCT (Reactant), RACT (Reactant or Reagent). 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yuan, Qian published the artcileTriptycene-based dicationic guanidinium ionic liquid: A novel stationary phase of high selectivity towards a wide range of positional and structural isomers, Product Details of C5H12O, the main research area is triptycene derivative dicationic guanidinium ionic liquid stationary GC isomer; Aromatic and aliphatic isomers; Dicationic guanidinium ionic liquid, gas chromatography; Essential oil; Separation performance; Triptycene-based stationary phase.

This work presents a new triptycene-based dicationic guanidinium ionic liquid (TPG) as the stationary phase for gas chromatog. (GC). To knowledge, this is the 1st example of employing a dicationic guanidinium ionic liquid (GIL) for chromatog. analyses. As a result, the TPG column exhibited moderate polarity and column efficiency of 3840 plates/m and 3120 plates/m measured by naphthalene and 1-octanol at 120°, resp. Particularly, the TPG column exhibited distinctly advantageous performance for the challenging Grob test mixture and the isomer mixture of phenols and anilines over the monocationic GIL and its counterpart with dicationic immidazolium units (TP-2IL). Also, it showed higher selectivity towards the isomers of alkanes, alcs., diethylbenzenes, bromotoluenes, bromonitrobenzenes than the com. DB-35MS column. Also, the TPG column achieved improved thermal stability over the GIL column and excellent repeatability with the relative standard deviation values of 0.01-0.05% for run-to-run, 0.11-0.24% for day-to-day and 2.4-4.1% for column-to-column. Its application to GC-MS anal. of the essential oil of Mentha haplocalyx proved its good potential for anal. of complex samples.

Journal of Chromatography A published new progress about Alkanes Role: ANT (Analyte), PEP (Physical, Engineering or Chemical Process), PRP (Properties), ANST (Analytical Study), PROC (Process). 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Product Details of C5H12O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ponomarev, A. V. published the artcileEffect of Boiling on the Mechanism of Formation and Decay of Hydroxyalkyl Radicals, Recommanded Product: 3-Pentanol, the main research area is propanol radial reaction mechanism.

The effect of the boiling state on the reaction mechanism of 11 free radicals formed upon irradiation of 1-propanol with 8 MeV accelerated electrons is considered. Compared to radiolysis at room temperature, radiolysis at boiling results in an increase in 1-propanol degradation yield from (10.1 ± 0.9) to (13.3 ± 0.9) mol./100 eV. Boiling shows the largest effect on the radiolytic cleavage of the C(1)-H and C(2)-H bonds and almost doubles the yield of hydroxyalkyl radicals. In particular, the boiling effect is due to the suppression of the cage effect, a decrease in the relative role of intermol. relaxation, and an increase in the processes of radicals exchange and combination.

Russian Journal of Physical Chemistry B published new progress about Boiling. 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Recommanded Product: 3-Pentanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ponomarev, A. V. published the artcileAcceleration of radical exchange and combination in 1-propanol under irradiation and boiling, Application In Synthesis of 584-02-1, the main research area is propanol radical bond cleavage radiolysis reaction mechanism.

The yield of radiolytic degradation of 1-propanol is 13.3 ± 0.9 mols./100 eV in a boiling state and 10.1 ± 0.9 mols./100 eV in ambient conditions when irradiated with 8 MeV accelerated electrons. Boiling increases the yields of diols by 1.7 times and of heavy monohydric alcs. arising via the radical combination by 1.3 times. At the same time, due to boiling, the total yield of methanol and ethanol decreases 2.1 times, and the yield of aldehydes and hydrocarbons – 1.3 times. Boiling accelerates the dissociation of some radicals and radical-cations, facilitates the radical exchange and favors a combination of hydroxypropyl radicals. However, both in liquid and boiling alc., the total yield of splitting of C-H bonds remains approx. twice as high as C-C bonds.

Radiation Physics and Chemistry published new progress about C-C bond cleavage. 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Application In Synthesis of 584-02-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ding, Shi published the artcileDesign, synthesis and structure-activity relationship evaluation of novel LpxC inhibitors as Gram-negative antibacterial agents, Related Products of alcohols-buliding-blocks, the publication is Bioorganic & Medicinal Chemistry Letters (2018), 28(2), 94-102, database is CAplus and MEDLINE.

LpxC inhibitors are new-type antibacterial agents developed in the last twenty years, mainly against Gram-neg. bacteria infections. To develop novel LpxC inhibitors with good antibacterial activities and biol. metabolism, the authors summarized the basic skeleton of reported LpxC inhibitors, designed and synthesized several series of compounds and tested their antibacterial activities against Escherichia coli and Pseudomonas aeruginosa in vitro. Structure-activity relations are discussed. The metabolism stability of YDL-2, YDL-5, YDL-8, YDL-14, YDL-20-YDL-23 were evaluated in liver microsomes, which indicated that the 2-amino iso-Pr group may be a preferred structure than the 2-hydroxy Et group in the design of LpxC inhibitors.

Bioorganic & Medicinal Chemistry Letters published new progress about 57044-25-4. 57044-25-4 belongs to alcohols-buliding-blocks, auxiliary class Epoxides,Chiral,Aliphatic hydrocarbon chain,Alcohol, name is (R)-Oxiran-2-ylmethanol, and the molecular formula is C3H6O2, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Powis, Ivan published the artcileA photoionization investigation of small, homochiral clusters of glycidol using circularly polarized radiation and velocity map electron-ion coincidence imaging, Recommanded Product: (R)-Oxiran-2-ylmethanol, the publication is Physical Chemistry Chemical Physics (2014), 16(2), 467-476, database is CAplus and MEDLINE.

A detailed study of the valence photoionization of small homochiral glycidol (C₃O₂H₆) clusters is carried out with the help of circularly-polarized VUV synchrotron radiation by recording photoionization-based spectroscopic data detected by velocity map electron imaging with coincidence ion selection. We show that information on the stability of cationic as well as neutral chiral clusters can be obtained with enhanced sensitivity by examining the chiral fingerprint encapsulated in Photoelectron CD (PECD) spectra. In particular, by varying the clustering conditions we demonstrate that the PECD signal effectively carries the signature of the neutral precursor species, prior to any fragmentation of the ion, as may be inferred from the below-threshold monomer measurements (including ion imaging). Here the monomer’s direct ionization channel is closed and the monomer ion hence must result exclusively as a fragment from dissociative ionization of the dimer (or higher) clusters. At higher photon energies, the mass-selection on the electron spectroscopy data, achieved through filtering the electron images in coincidence with selected ion masses, evidently succeeds in providing a degree of size-selection on the neutral clusters being ionized with, in particular, a clear differentiation of monomer and dimer PECD, showing the strong sensitivity of this chiroptical effect to the non-local long-range mol. potential.

Physical Chemistry Chemical Physics published new progress about 57044-25-4. 57044-25-4 belongs to alcohols-buliding-blocks, auxiliary class Epoxides,Chiral,Aliphatic hydrocarbon chain,Alcohol, name is (R)-Oxiran-2-ylmethanol, and the molecular formula is C3H6O2, Recommanded Product: (R)-Oxiran-2-ylmethanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Gaiser, Birgit I. published the artcileProbing the Existence of a Metastable Binding Site at the β₂-Adrenergic Receptor with Homobivalent Bitopic Ligands, Application In Synthesis of 57044-25-4, the publication is Journal of Medicinal Chemistry (2019), 62(17), 7806-7839, database is CAplus and MEDLINE.

Herein, we report the development of bitopic ligands aimed at targeting the orthosteric binding site (OBS) and a metastable binding site (MBS) within the same receptor unit. Previous mol. dynamics studies on ligand binding to the β₂-adrenergic receptor (β₂AR) suggested that ligands pause at transient, less-conserved MBSs. We envisioned that MBSs can be regarded as allosteric binding sites and targeted by homobivalent bitopic ligands linking two identical pharmacophores. Such ligands were designed based on docking of the antagonist (S)-alprenolol into the OBS and an MBS and synthesized. Pharmacol. characterization revealed ligands with similar potency and affinity, slightly increased β₂/β₁AR-selectivity, and/or substantially slower β₂AR off-rates compared to (S)-alprenolol. Truncated bitopic ligands suggested the major contribution of the metastable pharmacophore to be a hydrophobic interaction with the β₂AR, while the linkers alone decreased the potency of the orthosteric fragment. Altogether, the study underlines the potential of targeting MBSs for improving the pharmacol. profiles of ligands.

Journal of Medicinal Chemistry published new progress about 57044-25-4. 57044-25-4 belongs to alcohols-buliding-blocks, auxiliary class Epoxides,Chiral,Aliphatic hydrocarbon chain,Alcohol, name is (R)-Oxiran-2-ylmethanol, and the molecular formula is C3H6O2, Application In Synthesis of 57044-25-4.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Delgado, Jose A. C. published the artcileBiocompatible photoinduced alkylation of dehydroalanine for the synthesis of unnatural α-amino acids, Category: alcohols-buliding-blocks, the publication is Organic Letters (2021), 23(13), 5251-5255, database is CAplus and MEDLINE.

A site-selective alkylation of dehydroalanine to access protected unnatural amino acids is described. The protocol is characterized by the wide nature of alkyl radicals employed, mild conditions, and functional group compatibility. This protocol is further extended to access peptides, late-stage functionalization of pharmaceuticals, and enantioenriched amino acids.

Organic Letters published new progress about 96-20-8. 96-20-8 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 2-Aminobutan-1-ol, and the molecular formula is C4H11NO, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts