Tag: M.W=50-100

Yu, Hang published the artcilePotential of resveratrol in mitigating advanced glycation end-products formed in baked milk and baked yogurt, Name: 3-Pentanol, the main research area is baked milk yogurt resveratrol mitigating glycation end product; Advanced glycation end-products; Baked milk; Baked yogurt; Maillard reaction; Resveratrol.

Throughout the processing, a long-time-high-temperature baking procedure was involved to enhance the formation of a brownish color and desirable flavors; meanwhile, advanced glycation end-products (AGEs) were extensively produced through Maillard reaction (MR). The resveratrol at 1μmol/L was achieved the highest inhibitory rate against the formation of dicarbonyl compounds in the baked milk (3-deoxyglucosone (3-DG): 68.77%, methylglyoxal (MG): 50.46%) and baked yogurt (3-DG: 35.50%, MG: 37.11%). The content of N-(carboxymethyl)lysine (CML) and N-(hydroxyethyl) lysine (CEL) as the two commonly detected AGEs were decreased by higher than 30% and 27% in the baked milk and baked yogurt, resp., when the concentration of resveratrol was 0.1μmol/L. Moreover, the generation of furosine was significantly inhibited by 1μmol/L resveratrol, which was decreased to less than 40% and 60% in the baked milk and baked yogurt, resp. Furthermore, the addnl. level of 0.1μmol/L resveratrol achieved a high inhibitory effect of AGEs, and such an addnl. level would not alter the color and flavor profile of the baked milk and baked yogurt. Considering the high solubility of resveratrol in milk fat, it is speculated that resveratrol mainly acted at an early stage of the degradation, i.e., through the inhibition of the autocatalytic lipid oxidation that generates dicarbonyl compounds but played less as a dicarbonyl compounds scavenger.

Food Research International published new progress about Maillard reaction. 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Name: 3-Pentanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Li, Jing published the artcileN-donor ligand supported “”ReO2+””: a pre-catalyst for the deoxydehydration of diols and polyols, Name: 3-Pentanol, the main research area is ligand supported rhenium oxide catalyst diol polyol deoxydehydration.

A selected number of tetradentate N2Py2 ligand-supported ReO2+ complexes and a monodentate pyridine-supported ReO2+ complex have been investigated as catalysts for the deoxydehydration (DODH) of diols and polyols. In situ 1H NMR experiments showed that these N-donor ligand-supported ReO2+ complexes are only the pre-catalyst of the DODH reaction. Treatment of (N2Py2) ReO2+ with an excess amount of water generates an active species for DODH catalysis; use of the Re-product of this reaction shows a much shorter induction period compared to the pristine complex. No ligand is coordinated to the “”water-treated”” complex indicating that the real catalyst is formed after ligand dissociation IR anal. suggested this catalyst to be a rhenium-oxide/hydroxide oligomer. The monodentate pyridine ligand is much easier to dissociate from the metal center than a tetradentate N2Py2 ligand, which makes the Py4ReO2+ -initiated DODH reaction more efficient. For the Py4ReO2+ -initiated DODH of diols and biomass-based polyols, both PPh3 and 3-pentanol could be used as a reductant. Excellent olefin yields are achieved.

Catalysts published new progress about Crystal structure. 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Name: 3-Pentanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Saidi, Chourouk Nait published the artcilePredictions of solvation Gibbs free energies with COSMO-SAC approaches, Safety of 3-Pentanol, the main research area is liquid phase solvation Gibbs free energy activity coefficient simulation.

The modeling of a detailed kinetics mechanism in the liquid phase is still not well understood, and the description of solvent effect on reaction rates remains a challenge. Green and co-workers proposed an approach to predict the kinetic constants in liquid phases, which is based on a correction of the kinetic constants in the gas phase. The correction term in Green′s approach involves the solvation Gibbs free energies of the chem. species involved in the reactions. Examples of applications of the method are the kinetic modeling of the oxidation of liquid fuels or the catalytic pyrolysis of biomass. However, an accurate thermodn. model is required to predict the solvation energies. In this work, several predictive models of solvation energies are compared to the large set of exptl. data reported recently by Moine et al. [J. Phys. Chem. Reference Data, 46, 2017] in the CompSol database. Activity coefficients and solvation Gibbs free energies were calculated with different versions of the COSMO-SAC thermodn. model. We propose a re-optimization of the universal parameters of these COSMO-SAC models, and extend them to CPCM cavities. It is found that these approaches are in general much more accurate than the Abraham solvation model that is usually employed in Green′s approach.

Fluid Phase Equilibria published new progress about Chemical potential. 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Safety of 3-Pentanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ramesh, Madhan published the artcileHalf-Sandwich η6-p-Cymene) Ruthenium(II) complexes bearing 5-Amino-1-Methyl-3-Phenylpyrazole Schiff base ligands: Synthesis, structure and catalytic transfer hydrogenation of ketones, Related Products of alcohols-buliding-blocks, the main research area is ruthenium Schiff base complex preparation; alc preparation; ketone transfer hydrogenation ruthenium catalyst.

New (η6-p-cymene)ruthenium(II) complexes containing Schiff base ligands of the general composition [RuCl(η-p-cymene)(L)] were synthesized and screened for their efficiency as catalysts in the transfer hydrogenation of various ketones to alcs. RCH(OH)R1 [R = Et, Ph, 4-ClC6H4, etc.; R1 = Me, Et, Ph; RR1 = (CH2)4, (CH2)5] showing excellent conversion up to 99%. The complexes were characterized by anal. and spectral (FT-IR, UV-Vis, 1H NMR and 13C NMR) methods and the mol. structure of complex I was determined by single crystal X-ray diffraction studies, revealing a pseudo-octahedral piano stool geometry around ruthenium(II) ion. Under the optimized conditions, the influence of base, reaction temperature and substrate scope was also reported.

Journal of Organometallic Chemistry published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Weber, Stefan published the artcileRethinking Basic Concepts-Hydrogenation of Alkenes Catalyzed by Bench-Stable Alkyl Mn(I) Complexes, Recommanded Product: 3-Pentanol, the main research area is alkene hydrogenation alkyl manganese complex catalyst.

An efficient additive-free manganese-catalyzed hydrogenation of alkenes to alkanes with mol. hydrogen is described. This reaction is atom economic, implementing an inexpensive, earth-abundant nonprecious metal catalyst. The most efficient precatalyst is the bench-stable alkyl bisphosphine Mn(I) complex fac-[Mn(dippe)(CO)3CH2CH2CH3Pr]. The catalytic process is initiated by migratory insertion of a CO ligand into the Mn-alkyl bond to yield an acyl intermediate which undergoes rapid hydrogenolysis to form the active 16e Mn(I) hydride catalyst [Mn(dippe)(CO)2(H)]. A range of mono- and disubstituted alkenes were efficiently converted into alkanes in good to excellent yields. The hydrogenation of 1-alkenes and 1,1-disubstituted alkenes proceeds at 25°, while 1,2-disubstituted alkenes require a reaction temperature of 60°. In all cases, a catalyst loading of 2 mol % and a hydrogen pressure of 50 bar were applied. A mechanism based on DFT calculations is presented, which is supported by preliminary exptl. studies.

ACS Catalysis published new progress about Alkanes Role: SPN (Synthetic Preparation), PREP (Preparation). 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Recommanded Product: 3-Pentanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Karakas, Duygu Elma published the artcileKetone transfer hydrogenation reactions catalyzed by catalysts based on a phosphinite ligand, COA of Formula: C5H12O, the main research area is furanylethyldiphenylphosphinite preparation ruthenium iridium complexation; ketone transfer hydrogenation catalyzed furanylethyldiphenylphosphinite ruthenium iridium complex.

Reaction of (±)-1-(2-furyl)ethanol with an equivalent Ph2PCl in the presence of Et3N proceeds in dry toluene under an argon atm. to give 1-(furan-2-yl)ethyldiphenylphosphinite (1) in good yield. Mononuclear complexes [dichloro(η6-p-cymene)(1-furan-2-ylethyldiphenylphosphinite)ruthenium(II)] (2), [dichloro(η6-benzene)(1-furan-2-ylethyldiphenylphosphinite)ruthenium(II)] (3), [chloro(η4-1,5-cyclooctadiene)(1-furan-2-ylethyldiphenylphosphinite)rhodium(I)] (4) and [dichloro(η5-pentamethylcyclopentadienyl)(1-furan-2-ylethyldiphenylphosphinite)iridium(III)] (5) were synthesized and characterized by microanal., IR, MS, and NMR spectroscopies. The complexes are employed as catalysts in transfer hydrogenation of aromatic ketones. The complexes catalyzed reduction of a variety of aromatic ketone substrates bearing electron-withdrawing or donating substituents with very high conversion rates (up to 99%); 5 was the most efficient catalyst for the transfer hydrogenation of ketones.

Journal of Coordination Chemistry published new progress about Aryl ketones Role: RCT (Reactant), RACT (Reactant or Reagent). 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, COA of Formula: C5H12O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yan, Linjie published the artcileDesign, synthesis and evaluation of 2′-acetylene-7-deaza-adenosine phosphoamidate derivatives as anti-EV71 and anti-EV-D68 agents, Recommanded Product: 3-Pentanol, the main research area is alkylaminopyrrolopyrimidinylethynyl tetrahydrofuranylmethoxyphenoxyphosphorylaminopropanoate preparation diastereoselective antiviral SAR pharmacokinetic; Antiviral; Enterovirus; NITD008; Nucleoside/nucleotide inhibitor.

A series of phosphoamidate derivatives I [R1 = Me, iso-Bu, cyclohexyl etc.; R2 = H, Me, benzyl etc.] (NITD008) were synthesized and evaluated for their in-vitro antiviral activities against the enteroviruses EV71 and EV-D68. The phosphoamidate containing I [R1 = n-hexyl; R2 = Me] a hexyl ester of L-alanine exhibited the most promising activity against EV71 (IC50 = 0.13 ± 0.08 μM) and were 4-times more potent than NITD008. Meanwhile, the derivative containing a cyclohexyl ester of L-alanine I [R1 = cyclohexyl; R2 = Me] exhibited the most potent activity with high selectivity index against both EV71 (IC50 = 0.19 ± 0.27 μM, SI = 117.00) and EV-D68 (IC50 = 0.17 ± 0.16 μM, SI = 130.76), which were both higher than that of NITD008. The results indicated that the phosphoamidate I [R1 = cyclohexyl; R2 = Me] were the most promising candidate for further development as antiviral agents for the treatment of both EV71 and EV-D68 infection.

European Journal of Medicinal Chemistry published new progress about Amino acids Role: RCT (Reactant), RACT (Reactant or Reagent). 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Recommanded Product: 3-Pentanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yang, Ji published the artcileDirect synthesis of adipic acid esters via palladium-catalyzed carbonylation of 1,3-dienes, Recommanded Product: 3-Pentanol, the main research area is palladium pyridyl bidentate phosphine ligand catalyzed carbonylation diene alc; adipic acid ester green preparation carbonylation diene alc.

The direct carbonylation of 1,3-butadiene offers the potential for a more cost-efficient and environmentally benign route to industrially important adipic acid derivatives However, owing to the complex reaction network of regioisomeric carbonylation and isomerization pathways, a selective practical catalyst for this process has thus far proven elusive. Here, we report the design of a pyridyl-substituted bidentate phosphine ligand (HeMaRaphos) that, upon coordination to palladium, catalyzes adipate diester formation from 1,3-butadiene, carbon monoxide, and butanol with 97% selectivity and 100% atom-economy under industrially viable and scalable conditions (turnover number > 60,000). This catalyst system also affords access to a variety of other di- and triesters from 1,2- and 1,3-dienes.

Science (Washington, DC, United States) published new progress about 1,3-Alkadienes Role: RCT (Reactant), RACT (Reactant or Reagent). 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Recommanded Product: 3-Pentanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Man published the artcileMerging N-Hydroxyphthalimide into Metal-Organic Frameworks for Highly Efficient and Environmentally Benign Aerobic Oxidation, Safety of 3-Pentanol, the main research area is hydroxyphthalimide metal organic framework green oxidation catalyst; N-hydroxyphthalimide; aerobic oxidation; heterogeneous catalysis; metal-organic frameworks; nitroxyl radicals.

Two highly efficient metal-organic framework catalysts TJU-68-NHPI and TJU-68-NDHPI have been successfully synthesized through solvothermal reactions of which the frameworks are merged with N-hydroxyphthalimide (NHPI) units, resulting in the decoration of pore surfaces with highly active nitroxyl catalytic sites. When t-Bu nitrite (TBN) is used as co-catalyst, the as-synthesized MOFs are demonstrated to be highly efficient and recyclable catalysts for a novel three-phase heterogeneous oxidation of activated C-H bond of primary and secondary alcs., and benzyl compounds under mild conditions. Based on the high efficiency and selectivity, an environmentally benign system with good sustainability, mild conditions, simple work-up procedure has been established for practical oxidation of a wide range of substrates.

Chemistry – A European Journal published new progress about Aldehydes Role: SPN (Synthetic Preparation), PREP (Preparation). 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Safety of 3-Pentanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Panda, Surajit published the artcileEfficient α-Alkylation of Arylacetonitriles with Secondary Alcohols Catalyzed by a Phosphine-Free Air-Stable Iridium(III) Complex, Category: alcohols-buliding-blocks, the main research area is iridium complex catalyzed alkylation arylacetonitrile secondary alc.

A well-defined and readily available air-stable dimeric iridium(III) complex catalyzed α-alkylation of arylacetonitriles using secondary alcs. with the liberation of water as the only byproduct is reported. The α-alkylations were efficiently performed at 120°C under solvent-free conditions with very low (0.1-0.01 mol %) catalyst loading. Various secondary alcs. including cyclic and acyclic alcs. and a wide variety of arylacetonitriles bearing different functional groups were converted into the corresponding α-alkylated products in good yields. Mechanistic study revealed that the reaction proceeds via alc. activation by metal-ligand cooperation with the formation of reactive iridium-hydride species.

Journal of Organic Chemistry published new progress about Acetonitriles Role: RCT (Reactant), RACT (Reactant or Reagent). 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts